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The map label for this gene is endo I [H]

Identifier: 153937431

GI number: 153937431

Start: 811226

End: 813079

Strand: Direct

Name: endo I [H]

Synonym: CLC_0785

Alternate gene names: 153937431

Gene position: 811226-813079 (Clockwise)

Preceding gene: 153937814

Following gene: 153936477

Centisome position: 21.57

GC content: 31.88

Gene sequence:

>1854_bases
ATGAAAAACACCAAATTAATAAAATTAGTAGCTGGTATTATGGCTGCTACATTTTCACTGTCGCTTTTAACAACAAAAGT
AGAGGCAAAAAATATTGAAAATAAAAATACTAAAAATGAAGTTAAACAAACTGTTAATAGTAAAGATTTAGAAAGAAAGT
TAATTGGATATTTCCCAGAGTGGGCCTATAATAGTGAAGCTCAAGGATATTTTAAGGTTACTGATTTACAATGGGATTCT
TTAACTCATATTCAATATTCCTTTGCAATGGTGGATCAAGCTACAAATAAAATTAAATTAGGGGACAAACATGCCGCATT
GGAAGAGGAATTTAAAAATTATAATTTATCTTATAAAGGGAAAAAGGTAGAGTTAGATCCTAATCTCCCGTATAAAGGTC
ACTTTAATTTATTACAAACTATGAAAAAACAATATCCTGATGTTAATTTGCTTATATCAGTAGGTGGATGGGCTGGAAGT
AGAGGATTTTATACAATGCTTGATACGGATGAAGGAATAAATACCTTTGCAGATTCTTGCGTTGATTTTATAAAGAAGTA
TAATTTTGATGGTGTTGATATTGATTTTGAATATCCATCTTCAACAAGTCAGTCAGGAAATCCAGCAGATTTTGACTTAT
CTGAACCTAGAAGGGCTAAATTAAATGAGAGATATAATATACTCATGAAAACACTAAGAGAAAAAATAGATGCAGCTTCT
AAAAAGGATAATAAAGATTATATATTATCTGCTGCAGTTACAGCATCACCTTGGGTACTAGGTGGGGTTAAAGATAACAC
CTATGCTAAGTATCTAGATTTCTTAAGTGTTATGTCCTATGACTATCATGGTGGATGGAATGAATATGTTGAAAATTTAG
CAGGTATTTATCCAGATCCAAAAGATAGGGAAACTGCCAGTCAAATCATGCCAACACTTTGTATGGATTGGGCTTATAGA
TATTACAGAGGAATTTTGCCACCTGAAAAAATATTAATGGGTATACCATACTATACTAGAGGATGGGAAAATGTACAAGG
TGGACAAAATGGACTTCATGGATCAAGTAGAACCCCTGCATCTGGTAAGTATAATATTTGGGGAGACGATTTAGATAACG
ATGGAAAGTTAGAACCAGCAGGTGCTAATCCGTTATGGCATGTATTAAACCTTATGGAAAAGGATAATAATTTAAAAGTA
TATTGGGATGATGTAGAAAAGGTGCCATATGTTTGGCAAAATCAAGAAAGAGTTTTCTTATCCTTTGAAAATGAAAGATC
TATTGATGAGAGACTTAATTATATTAAAAATAAAAATCTAGGTGGAGCATTAATTTGGGTTATGAACGGTGATTATGGAC
TAAATCCTAACTATGAAGAAGGTTCAAGTGATATAAATAAAGGTAAGTATACTTTTGGTGATACTTTAACTAAGAGATTA
AGCAATGGCTTAACTAATATGGGAGCATGCAGTAAAACACCAGAGGATTCTAATAATTCCCTAGAACCTATAAATGTTTC
AGTGAACTTCGGTGGTAGCTATGATCATCCGAATTACACTTATGATATAAAGGTGAAAAATTATACAGGTAAAGAAATTA
AGGGAGGATGGGAAGTATCCTTTGATTTACCAAAATCAGCATTATATAAGTCTTCTTGGGGAGGTAACTACACTTTAAAA
GATAATGGAGATTTTACAACAGTTACAATAAAATCTGGTAACTGGCAAAATATTAATGCTGGTGCTACTGTTAACCTTCA
AGGAATGATAGGACTATGCTTTTCAGACGTTAGAAATATTAAATTTAATGATATGAAACCTGTAGGAGATCAAAAAATTA
TTCAACAAAAATAG

Upstream 100 bases:

>100_bases
AATTACTAAAACAATATAACCAAAATTTATATTTGAAACCAAATGGCAAGATTATCATAGCATAGTATTATAATATAGAA
ATAAAATAGGAGGATTTACA

Downstream 100 bases:

>100_bases
ATAGTAAAAAATTAAAATAAATGTTTCTATTATTCCGTTTATAAATAAGACAGTGCCTATGTATTTTTATAGTACTAGCA
CTGTCTTGTTAATGTGTAGC

Product: putative chitinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 617; Mature: 617

Protein sequence:

>617_residues
MKNTKLIKLVAGIMAATFSLSLLTTKVEAKNIENKNTKNEVKQTVNSKDLERKLIGYFPEWAYNSEAQGYFKVTDLQWDS
LTHIQYSFAMVDQATNKIKLGDKHAALEEEFKNYNLSYKGKKVELDPNLPYKGHFNLLQTMKKQYPDVNLLISVGGWAGS
RGFYTMLDTDEGINTFADSCVDFIKKYNFDGVDIDFEYPSSTSQSGNPADFDLSEPRRAKLNERYNILMKTLREKIDAAS
KKDNKDYILSAAVTASPWVLGGVKDNTYAKYLDFLSVMSYDYHGGWNEYVENLAGIYPDPKDRETASQIMPTLCMDWAYR
YYRGILPPEKILMGIPYYTRGWENVQGGQNGLHGSSRTPASGKYNIWGDDLDNDGKLEPAGANPLWHVLNLMEKDNNLKV
YWDDVEKVPYVWQNQERVFLSFENERSIDERLNYIKNKNLGGALIWVMNGDYGLNPNYEEGSSDINKGKYTFGDTLTKRL
SNGLTNMGACSKTPEDSNNSLEPINVSVNFGGSYDHPNYTYDIKVKNYTGKEIKGGWEVSFDLPKSALYKSSWGGNYTLK
DNGDFTTVTIKSGNWQNINAGATVNLQGMIGLCFSDVRNIKFNDMKPVGDQKIIQQK

Sequences:

>Translated_617_residues
MKNTKLIKLVAGIMAATFSLSLLTTKVEAKNIENKNTKNEVKQTVNSKDLERKLIGYFPEWAYNSEAQGYFKVTDLQWDS
LTHIQYSFAMVDQATNKIKLGDKHAALEEEFKNYNLSYKGKKVELDPNLPYKGHFNLLQTMKKQYPDVNLLISVGGWAGS
RGFYTMLDTDEGINTFADSCVDFIKKYNFDGVDIDFEYPSSTSQSGNPADFDLSEPRRAKLNERYNILMKTLREKIDAAS
KKDNKDYILSAAVTASPWVLGGVKDNTYAKYLDFLSVMSYDYHGGWNEYVENLAGIYPDPKDRETASQIMPTLCMDWAYR
YYRGILPPEKILMGIPYYTRGWENVQGGQNGLHGSSRTPASGKYNIWGDDLDNDGKLEPAGANPLWHVLNLMEKDNNLKV
YWDDVEKVPYVWQNQERVFLSFENERSIDERLNYIKNKNLGGALIWVMNGDYGLNPNYEEGSSDINKGKYTFGDTLTKRL
SNGLTNMGACSKTPEDSNNSLEPINVSVNFGGSYDHPNYTYDIKVKNYTGKEIKGGWEVSFDLPKSALYKSSWGGNYTLK
DNGDFTTVTIKSGNWQNINAGATVNLQGMIGLCFSDVRNIKFNDMKPVGDQKIIQQK
>Mature_617_residues
MKNTKLIKLVAGIMAATFSLSLLTTKVEAKNIENKNTKNEVKQTVNSKDLERKLIGYFPEWAYNSEAQGYFKVTDLQWDS
LTHIQYSFAMVDQATNKIKLGDKHAALEEEFKNYNLSYKGKKVELDPNLPYKGHFNLLQTMKKQYPDVNLLISVGGWAGS
RGFYTMLDTDEGINTFADSCVDFIKKYNFDGVDIDFEYPSSTSQSGNPADFDLSEPRRAKLNERYNILMKTLREKIDAAS
KKDNKDYILSAAVTASPWVLGGVKDNTYAKYLDFLSVMSYDYHGGWNEYVENLAGIYPDPKDRETASQIMPTLCMDWAYR
YYRGILPPEKILMGIPYYTRGWENVQGGQNGLHGSSRTPASGKYNIWGDDLDNDGKLEPAGANPLWHVLNLMEKDNNLKV
YWDDVEKVPYVWQNQERVFLSFENERSIDERLNYIKNKNLGGALIWVMNGDYGLNPNYEEGSSDINKGKYTFGDTLTKRL
SNGLTNMGACSKTPEDSNNSLEPINVSVNFGGSYDHPNYTYDIKVKNYTGKEIKGGWEVSFDLPKSALYKSSWGGNYTLK
DNGDFTTVTIKSGNWQNINAGATVNLQGMIGLCFSDVRNIKFNDMKPVGDQKIIQQK

Specific function: Hydrolyzes chitin oligosaccharides; (GlcNAc)4 to (GlcNAc)2 and (GlcNAc)5,6 to (GlcNAc)2 and (GlcNAc)3. Inactive towards chitin, glucosamine oligosaccharides, glycoproteins and glycopeptides containing (GlcNAc)2 [H]

COG id: COG3325

COG function: function code G; Chitinase

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 18 family [H]

Homologues:

Organism=Homo sapiens, GI4502809, Length=438, Percent_Identity=26.2557077625571, Blast_Score=132, Evalue=9e-31,
Organism=Homo sapiens, GI58386720, Length=409, Percent_Identity=25.9168704156479, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI133893286, Length=461, Percent_Identity=25.1626898047722, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI68533255, Length=415, Percent_Identity=24.578313253012, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI68533253, Length=415, Percent_Identity=24.578313253012, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI42542398, Length=347, Percent_Identity=25.9365994236311, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI144226251, Length=403, Percent_Identity=22.3325062034739, Blast_Score=103, Evalue=6e-22,
Organism=Homo sapiens, GI68533260, Length=333, Percent_Identity=25.8258258258258, Blast_Score=101, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71995504, Length=412, Percent_Identity=28.3980582524272, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17559362, Length=414, Percent_Identity=28.5024154589372, Blast_Score=142, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17563680, Length=411, Percent_Identity=27.2506082725061, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17551250, Length=488, Percent_Identity=23.7704918032787, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17535565, Length=331, Percent_Identity=29.3051359516616, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17531695, Length=442, Percent_Identity=23.7556561085973, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17535567, Length=314, Percent_Identity=27.3885350318471, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17535569, Length=480, Percent_Identity=26.4583333333333, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI32564165, Length=484, Percent_Identity=23.1404958677686, Blast_Score=99, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17536195, Length=317, Percent_Identity=27.4447949526814, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17539198, Length=324, Percent_Identity=24.6913580246914, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17531683, Length=312, Percent_Identity=24.3589743589744, Blast_Score=91, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320579, Length=395, Percent_Identity=23.5443037974684, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI221330815, Length=473, Percent_Identity=27.2727272727273, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24655584, Length=411, Percent_Identity=26.2773722627737, Blast_Score=129, Evalue=7e-30,
Organism=Drosophila melanogaster, GI45550474, Length=405, Percent_Identity=26.4197530864197, Blast_Score=125, Evalue=8e-29,
Organism=Drosophila melanogaster, GI21358195, Length=408, Percent_Identity=25.2450980392157, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI116007452, Length=407, Percent_Identity=24.0786240786241, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI22024049, Length=402, Percent_Identity=24.1293532338308, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI221329807, Length=413, Percent_Identity=21.5496368038741, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI161077700, Length=413, Percent_Identity=21.5496368038741, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24640248, Length=417, Percent_Identity=25.1798561151079, Blast_Score=87, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003610
- InterPro:   IPR009470
- InterPro:   IPR011583
- InterPro:   IPR001223
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF02839 CBM_5_12; PF06483 ChiC; PF00704 Glyco_hydro_18 [H]

EC number: =3.2.1.14 [H]

Molecular weight: Translated: 69920; Mature: 69920

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS01095 CHITINASE_18

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNTKLIKLVAGIMAATFSLSLLTTKVEAKNIENKNTKNEVKQTVNSKDLERKLIGYFPE
CCCCHHHHHHHHHHHHHHHHHHHEEEHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHCCCC
WAYNSEAQGYFKVTDLQWDSLTHIQYSFAMVDQATNKIKLGDKHAALEEEFKNYNLSYKG
CCCCCCCCCEEEEEECCCCCCCCEEEHHHHHHHCCCEEEECCHHHHHHHHHHCCCCEECC
KKVELDPNLPYKGHFNLLQTMKKQYPDVNLLISVGGWAGSRGFYTMLDTDEGINTFADSC
CEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEEEECCCCHHHHHHHH
VDFIKKYNFDGVDIDFEYPSSTSQSGNPADFDLSEPRRAKLNERYNILMKTLREKIDAAS
HHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
KKDNKDYILSAAVTASPWVLGGVKDNTYAKYLDFLSVMSYDYHGGWNEYVENLAGIYPDP
CCCCCCEEEEEEEECCCEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCC
KDRETASQIMPTLCMDWAYRYYRGILPPEKILMGIPYYTRGWENVQGGQNGLHGSSRTPA
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCHHHCCCCCCCCCCCCCCCCCCCCC
SGKYNIWGDDLDNDGKLEPAGANPLWHVLNLMEKDNNLKVYWDDVEKVPYVWQNQERVFL
CCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEECCCCEEEE
SFENERSIDERLNYIKNKNLGGALIWVMNGDYGLNPNYEEGSSDINKGKYTFGDTLTKRL
EECCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHH
SNGLTNMGACSKTPEDSNNSLEPINVSVNFGGSYDHPNYTYDIKVKNYTGKEIKGGWEVS
HCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCEEEE
FDLPKSALYKSSWGGNYTLKDNGDFTTVTIKSGNWQNINAGATVNLQGMIGLCFSDVRNI
ECCCHHHHHHCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCEEEECHHHHHHHHHHCCC
KFNDMKPVGDQKIIQQK
CCCCCCCCCCHHHHCCC
>Mature Secondary Structure
MKNTKLIKLVAGIMAATFSLSLLTTKVEAKNIENKNTKNEVKQTVNSKDLERKLIGYFPE
CCCCHHHHHHHHHHHHHHHHHHHEEEHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHCCCC
WAYNSEAQGYFKVTDLQWDSLTHIQYSFAMVDQATNKIKLGDKHAALEEEFKNYNLSYKG
CCCCCCCCCEEEEEECCCCCCCCEEEHHHHHHHCCCEEEECCHHHHHHHHHHCCCCEECC
KKVELDPNLPYKGHFNLLQTMKKQYPDVNLLISVGGWAGSRGFYTMLDTDEGINTFADSC
CEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEEEECCCCHHHHHHHH
VDFIKKYNFDGVDIDFEYPSSTSQSGNPADFDLSEPRRAKLNERYNILMKTLREKIDAAS
HHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
KKDNKDYILSAAVTASPWVLGGVKDNTYAKYLDFLSVMSYDYHGGWNEYVENLAGIYPDP
CCCCCCEEEEEEEECCCEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCC
KDRETASQIMPTLCMDWAYRYYRGILPPEKILMGIPYYTRGWENVQGGQNGLHGSSRTPA
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCHHHCCCCCCCCCCCCCCCCCCCCC
SGKYNIWGDDLDNDGKLEPAGANPLWHVLNLMEKDNNLKVYWDDVEKVPYVWQNQERVFL
CCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEECCCCEEEE
SFENERSIDERLNYIKNKNLGGALIWVMNGDYGLNPNYEEGSSDINKGKYTFGDTLTKRL
EECCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHH
SNGLTNMGACSKTPEDSNNSLEPINVSVNFGGSYDHPNYTYDIKVKNYTGKEIKGGWEVS
HCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCEEEE
FDLPKSALYKSSWGGNYTLKDNGDFTTVTIKSGNWQNINAGATVNLQGMIGLCFSDVRNI
ECCCHHHHHHCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCEEEECHHHHHHHHHHCCC
KFNDMKPVGDQKIIQQK
CCCCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969204 [H]