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The map label for this gene is thrS [H]

Identifier: 153937058

GI number: 153937058

Start: 226612

End: 228270

Strand: Direct

Name: thrS [H]

Synonym: CLC_0252

Alternate gene names: 153937058

Gene position: 226612-228270 (Clockwise)

Preceding gene: 153935961

Following gene: 153934840

Centisome position: 6.03

GC content: 26.94

Gene sequence:

>1659_bases
ATGGAGGGATTAAAATTATATATGCCTAATGGTAGTAATATTCTAGCATCTGGAGATAAAACCTTATATGATGTAGTAAA
AGAAAATAAATTACAAGATAATATACCTATTGTTTTAGGAAAAATAGATGAAGAATATTATGAACTAACTTCCACAGTGA
AAAAAGAGGGAGTATTCATTCCTGTAGATATAACAGATAGCATGGGATTAAAAACTTATGTTAGAACTTTGCAGTTTATA
TTTATAAAGGCGGTTTTAGATTTATATCCTGAATCTACTGTTGTTATAGAGCATTCTTTAGGCAAAGGACTATATGGTGA
AATTCATAAGACGCTATCACTAAATGAAAATGACATATTAAAGATTAAAAATAGAATGAATGAAATAATAAATAAAGACA
TAAAGATAAAAAAAATTTCAGTTAAAAAAGAAAGAGCTATAGAAATATTTAATGAATATAAAATGAAAGATAAAGTTAGA
CTTTTAAATCATATTCCACATGAAGAAGTGAAACTATATGAATTAGATGAAAGATATGATTATTTTTATGGACCTATGGC
ATATTCAACAGGGGCAATTAAAAATTTTGATATTATGTATTATGATCCAGGTTTTATATTAAGATACCCTAGAGAAAAAG
ATCCATTTAATATACCAGAGTTTGTTGAATATAAAAAGCTTACGAAAATATTTAGAGAAACAGAAAAATGGGCTAAAATT
TTAGATGTAGGGGATGTAGGAGCCCTAAACGATAAAGTTGTATATGGCGAAATAAAAGATATAATAAGAGTATCAGAGGC
CCTGCATGAAAAGAAAATAGCAAACATAGCAGATATGATATATGATAAAGAGAAGATAAAAATGGTATTAATATCAGGAC
CTTCATCATCAGGAAAAACTACCTTTGCTAATAGATTAGGGATTCAATTAAGAGTTAACGCTTTGATACCTGTGCCTATT
TCATTAGATAATTATTTTGTTAATAGAGAGGATACTCCCAAAGATGAAAATGGAGATTATGATTTTGAATCCATTGATGC
TCTAGATATAGATTTATTTAATGAAGATTTAAAACATATATTAAACGGAGAAGAGGTACCAATACCTACTTTCAACTTTA
AAAAAGGTAAAAGGGAATATGATGGTAAAAAGATAAAACTTCCTAAAAATGGGATACTCATTGTAGAGGGAATACATGGA
TTAAATCCAATATTAACAAGAGAAATACCGGATAAAAATAAATTTAAAATATATATAAGTGCATTAACTCAATTAAATAT
AGATAATCATAACAGAGTATCTACAACAGATGTAAGGATAATAAGAAGACTAGTTAGAGATTATTTATCAAGGGGTTATA
AAGGAGAAGAAACCTTAAAAATGTGGCCATCTATAAAAAGAGGAGAAGATAGAAATATATTTGTATTCCAAGAAAATGCA
GATGTAATGTTTAATTCCACAATAGTCTATGAACTTTGTATATTAAAAAAATATGCTCTTGCAGAACTTAACAAAATAGA
TAAAAACAGTACTGTTCATTATGAAGCAACTAGGTTAAAAAGTTTTTTAAACTTTTTTAAAGAAGTTGATATGAACTTAG
TTCCAAGTAATTCTATATTAAGGGAATTTATAGGTGGAAGTTGTTTCTATGAATATTAA

Upstream 100 bases:

>100_bases
TGTGGCAAGTTTAAATAAAAAATATGAATAAATATAGGTAACAAAATATAATAAATTGAATTATAATAATAGTACAGCCT
AAAATAAGGAGATGAATAAA

Downstream 100 bases:

>100_bases
TGAAATAAGGAAAGTGCGCTGCACTTTCCTTATTTTGCTTTAGTAACAACTTTATAGGGTAAGAATAAAATGAATATAAA
TAAAAATATTTTAAAGTATA

Product: putative threonyl-tRNA synthetase/uridine kinase

Products: NA

Alternate protein names: Threonine--tRNA ligase; ThrRS [H]

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MEGLKLYMPNGSNILASGDKTLYDVVKENKLQDNIPIVLGKIDEEYYELTSTVKKEGVFIPVDITDSMGLKTYVRTLQFI
FIKAVLDLYPESTVVIEHSLGKGLYGEIHKTLSLNENDILKIKNRMNEIINKDIKIKKISVKKERAIEIFNEYKMKDKVR
LLNHIPHEEVKLYELDERYDYFYGPMAYSTGAIKNFDIMYYDPGFILRYPREKDPFNIPEFVEYKKLTKIFRETEKWAKI
LDVGDVGALNDKVVYGEIKDIIRVSEALHEKKIANIADMIYDKEKIKMVLISGPSSSGKTTFANRLGIQLRVNALIPVPI
SLDNYFVNREDTPKDENGDYDFESIDALDIDLFNEDLKHILNGEEVPIPTFNFKKGKREYDGKKIKLPKNGILIVEGIHG
LNPILTREIPDKNKFKIYISALTQLNIDNHNRVSTTDVRIIRRLVRDYLSRGYKGEETLKMWPSIKRGEDRNIFVFQENA
DVMFNSTIVYELCILKKYALAELNKIDKNSTVHYEATRLKSFLNFFKEVDMNLVPSNSILREFIGGSCFYEY

Sequences:

>Translated_552_residues
MEGLKLYMPNGSNILASGDKTLYDVVKENKLQDNIPIVLGKIDEEYYELTSTVKKEGVFIPVDITDSMGLKTYVRTLQFI
FIKAVLDLYPESTVVIEHSLGKGLYGEIHKTLSLNENDILKIKNRMNEIINKDIKIKKISVKKERAIEIFNEYKMKDKVR
LLNHIPHEEVKLYELDERYDYFYGPMAYSTGAIKNFDIMYYDPGFILRYPREKDPFNIPEFVEYKKLTKIFRETEKWAKI
LDVGDVGALNDKVVYGEIKDIIRVSEALHEKKIANIADMIYDKEKIKMVLISGPSSSGKTTFANRLGIQLRVNALIPVPI
SLDNYFVNREDTPKDENGDYDFESIDALDIDLFNEDLKHILNGEEVPIPTFNFKKGKREYDGKKIKLPKNGILIVEGIHG
LNPILTREIPDKNKFKIYISALTQLNIDNHNRVSTTDVRIIRRLVRDYLSRGYKGEETLKMWPSIKRGEDRNIFVFQENA
DVMFNSTIVYELCILKKYALAELNKIDKNSTVHYEATRLKSFLNFFKEVDMNLVPSNSILREFIGGSCFYEY
>Mature_552_residues
MEGLKLYMPNGSNILASGDKTLYDVVKENKLQDNIPIVLGKIDEEYYELTSTVKKEGVFIPVDITDSMGLKTYVRTLQFI
FIKAVLDLYPESTVVIEHSLGKGLYGEIHKTLSLNENDILKIKNRMNEIINKDIKIKKISVKKERAIEIFNEYKMKDKVR
LLNHIPHEEVKLYELDERYDYFYGPMAYSTGAIKNFDIMYYDPGFILRYPREKDPFNIPEFVEYKKLTKIFRETEKWAKI
LDVGDVGALNDKVVYGEIKDIIRVSEALHEKKIANIADMIYDKEKIKMVLISGPSSSGKTTFANRLGIQLRVNALIPVPI
SLDNYFVNREDTPKDENGDYDFESIDALDIDLFNEDLKHILNGEEVPIPTFNFKKGKREYDGKKIKLPKNGILIVEGIHG
LNPILTREIPDKNKFKIYISALTQLNIDNHNRVSTTDVRIIRRLVRDYLSRGYKGEETLKMWPSIKRGEDRNIFVFQENA
DVMFNSTIVYELCILKKYALAELNKIDKNSTVHYEATRLKSFLNFFKEVDMNLVPSNSILREFIGGSCFYEY

Specific function: Thrs Is Also A Translational Repressor Protein, It Controls The Translation Of Its Own Gene By Binding To Its mRNA. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: 700 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR012675
- InterPro:   IPR004095
- InterPro:   IPR012676
- InterPro:   IPR002320
- InterPro:   IPR018163
- InterPro:   IPR012947 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF02824 TGS; PF00587 tRNA-synt_2b; PF07973 tRNA_SAD [H]

EC number: =6.1.1.3 [H]

Molecular weight: Translated: 64020; Mature: 64020

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGLKLYMPNGSNILASGDKTLYDVVKENKLQDNIPIVLGKIDEEYYELTSTVKKEGVFI
CCCCEEECCCCCEEEECCCHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCEEE
PVDITDSMGLKTYVRTLQFIFIKAVLDLYPESTVVIEHSLGKGLYGEIHKTLSLNENDIL
EEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCCCCHH
KIKNRMNEIINKDIKIKKISVKKERAIEIFNEYKMKDKVRLLNHIPHEEVKLYELDERYD
HHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCC
YFYGPMAYSTGAIKNFDIMYYDPGFILRYPREKDPFNIPEFVEYKKLTKIFRETEKWAKI
EEECCHHCCCCCCCCEEEEEECCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LDVGDVGALNDKVVYGEIKDIIRVSEALHEKKIANIADMIYDKEKIKMVLISGPSSSGKT
HCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCC
TFANRLGIQLRVNALIPVPISLDNYFVNREDTPKDENGDYDFESIDALDIDLFNEDLKHI
CHHHHCCEEEEEEEEEECEEECCCEEECCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHH
LNGEEVPIPTFNFKKGKREYDGKKIKLPKNGILIVEGIHGLNPILTREIPDKNKFKIYIS
HCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCHHCCCCCCCCCEEEEEE
ALTQLNIDNHNRVSTTDVRIIRRLVRDYLSRGYKGEETLKMWPSIKRGEDRNIFVFQENA
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCEEEEEECCC
DVMFNSTIVYELCILKKYALAELNKIDKNSTVHYEATRLKSFLNFFKEVDMNLVPSNSIL
CEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCHHHH
REFIGGSCFYEY
HHHHCCCEEECC
>Mature Secondary Structure
MEGLKLYMPNGSNILASGDKTLYDVVKENKLQDNIPIVLGKIDEEYYELTSTVKKEGVFI
CCCCEEECCCCCEEEECCCHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCEEE
PVDITDSMGLKTYVRTLQFIFIKAVLDLYPESTVVIEHSLGKGLYGEIHKTLSLNENDIL
EEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCCCCHH
KIKNRMNEIINKDIKIKKISVKKERAIEIFNEYKMKDKVRLLNHIPHEEVKLYELDERYD
HHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCC
YFYGPMAYSTGAIKNFDIMYYDPGFILRYPREKDPFNIPEFVEYKKLTKIFRETEKWAKI
EEECCHHCCCCCCCCEEEEEECCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LDVGDVGALNDKVVYGEIKDIIRVSEALHEKKIANIADMIYDKEKIKMVLISGPSSSGKT
HCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCC
TFANRLGIQLRVNALIPVPISLDNYFVNREDTPKDENGDYDFESIDALDIDLFNEDLKHI
CHHHHCCEEEEEEEEEECEEECCCEEECCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHH
LNGEEVPIPTFNFKKGKREYDGKKIKLPKNGILIVEGIHGLNPILTREIPDKNKFKIYIS
HCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCHHCCCCCCCCCEEEEEE
ALTQLNIDNHNRVSTTDVRIIRRLVRDYLSRGYKGEETLKMWPSIKRGEDRNIFVFQENA
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCEEEEEECCC
DVMFNSTIVYELCILKKYALAELNKIDKNSTVHYEATRLKSFLNFFKEVDMNLVPSNSIL
CEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCHHHH
REFIGGSCFYEY
HHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA