Click here to switch to the map view.

The map label for this gene is yqhT [H]

Identifier: 153937011

GI number: 153937011

Start: 2319951

End: 2321744

Strand: Direct

Name: yqhT [H]

Synonym: CLC_2188

Alternate gene names: 153937011

Gene position: 2319951-2321744 (Clockwise)

Preceding gene: 153937464

Following gene: 153937298

Centisome position: 61.69

GC content: 34.0

Gene sequence:

>1794_bases
ATGAAAGTATCTGAAAAACTTACAAAATTAAGGAACTTGATGACTGAAAAAAATATTGATATGTATATCGTACCTACTGC
TGATTTCCATCAAAGCGAATATGTAGGTGAACATTTCAAAGCTAGAAAATATATCACTGGGTTCTCTGGTTCTGCAGGAA
CTGCTGTTATAACAAAGGAAAACGCAGGACTATGGACAGATGGAAGATATTTCCTACAGGCTGGGAATCAATTAAAAGGA
ACCACTGTAGAATTATTTAAAATGGGCGAGCCTGGAGTTCCAACCATAGAAGAATATATCATGAACACACTTTCCGATAA
GGGCACTCTTGGATTTGATGGTCGTGTTGTTTCTATGGTAGATGGCCAAACTTATGAAAAAATATTGTCAAGTAAAAATG
CTAACATCAACTACGACTGTGATTTAATTAATGATATATGGGAAGATCGCCCATCTCTTTCTGAGGAACCAGCTTTTGAA
CTTGATATAAAATACACCGGAGAATCTACTGCTTCTAAATTAAAACGTGTTAGAGAAGCAATGACAGATGCAGGTACAAA
TGTACATGTTATTACATCTCTAGATGATATTGCGTGGATTCTTAACATACGTGGAAACGATATCGAGTTTTTCCCACTAG
TTTTAAGCTACCTTATTATTACAATGGATGAAGCTCATCTATTCATCAATGAAGATAAATTAAGTGATGAAATAAAATCA
AATCTTAAGAAAAATGGTGTGTCATTTATACATCCATATAATGAAATATACAAAGCAGTAAAAAAATTTAACACTTCTGA
CATTGTTTTAGTTGATCCAGCTAGAATGAATTATGCATTATATAATAATATTCCAAAAGATGTTAAAAAAGTAGAAAAAC
GCAATCCATCTGTTCTGTTTAAAGCTATGAAAAACCCAATTGAAATTGAAAATATTAAAAAAGCTCAAATAAAAGATGGA
GTAGCTCATACTAAATTTATGTACTGGCTTAAACATAATATAGGAAAAGAAACCATCACAGAAATAAGTGCTTCTAATAA
ACTAGATGAATTCCGTGCAGAACAAGGAGAATTTATACGTCCAAGCTTTGAACCTATTTCTTCATTTGCTGAACATGCTG
CTATAGTACACTATGCTCCAACTCCCGAAACAGATGTTGAACTAAAAGAAGGTTCTTTATTCTTAACAGATACTGGTGCT
GGTTTCTATGAAGGTTCTACAGACATTACAAGAACTTATGCATTAGGAGAAGTACCACAAATAATGAAAGATCACTTTAC
TCTAACTGTTAATAGTAATCTTCACCTTGCTCATGCAAAATTCCTTTATGGTTGTAATGGCATGAATTTGGATATCCTTG
CACGTGCTCCATTCTGGAATAGAAACTTAAACTTCAACCATGGTACAGGCCACGGTGTTGGATACTTAATGAACATTCAT
GAAGCACCAACTGGATTCAGATGGCAATATCGTCCAAACGAAACTCATCCTTTTGAAGAAGGAATGGTTATTACCGATGA
GCCTGGTATCTATATTGCAGGCTCACACGGTGTCCGTATTGAAAATGAACTTCTTGTATGCAAAGGCGAACAGAATGAAT
ACGGCCAATTCATGTACTTTGAACCAATTAGTTATGTGCCTATGGATTTAGACGCAATAAACCCTGACCTTATGACTGCA
GAAGAAAAAGCATGGTTAAATGAATATCATGAATCTGTATATAATAAAATTTCACCATACCTTACTGAAGAAGAAAAAAA
CTGGTTAAAGGAGTATACCAGAAAAATTTCATAA

Upstream 100 bases:

>100_bases
AATTCTTTCATGCACATTCCACTGATTGGGATAGTTTTCCTTCTTCTTTTGTGCTATAATTCTTATGAAAAGCAATATTA
ATTGAAGGGGGATTAATACA

Downstream 100 bases:

>100_bases
TTAAGCCCAATTGAAATAAGGTATGTAACAATGTCACAAGAAAAGCAAAAACATCCTATAGGCCTTTCACTAGTAAATAT
CTCTATAGCCCTCCAAAGTT

Product: M24 family metallopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 597; Mature: 597

Protein sequence:

>597_residues
MKVSEKLTKLRNLMTEKNIDMYIVPTADFHQSEYVGEHFKARKYITGFSGSAGTAVITKENAGLWTDGRYFLQAGNQLKG
TTVELFKMGEPGVPTIEEYIMNTLSDKGTLGFDGRVVSMVDGQTYEKILSSKNANINYDCDLINDIWEDRPSLSEEPAFE
LDIKYTGESTASKLKRVREAMTDAGTNVHVITSLDDIAWILNIRGNDIEFFPLVLSYLIITMDEAHLFINEDKLSDEIKS
NLKKNGVSFIHPYNEIYKAVKKFNTSDIVLVDPARMNYALYNNIPKDVKKVEKRNPSVLFKAMKNPIEIENIKKAQIKDG
VAHTKFMYWLKHNIGKETITEISASNKLDEFRAEQGEFIRPSFEPISSFAEHAAIVHYAPTPETDVELKEGSLFLTDTGA
GFYEGSTDITRTYALGEVPQIMKDHFTLTVNSNLHLAHAKFLYGCNGMNLDILARAPFWNRNLNFNHGTGHGVGYLMNIH
EAPTGFRWQYRPNETHPFEEGMVITDEPGIYIAGSHGVRIENELLVCKGEQNEYGQFMYFEPISYVPMDLDAINPDLMTA
EEKAWLNEYHESVYNKISPYLTEEEKNWLKEYTRKIS

Sequences:

>Translated_597_residues
MKVSEKLTKLRNLMTEKNIDMYIVPTADFHQSEYVGEHFKARKYITGFSGSAGTAVITKENAGLWTDGRYFLQAGNQLKG
TTVELFKMGEPGVPTIEEYIMNTLSDKGTLGFDGRVVSMVDGQTYEKILSSKNANINYDCDLINDIWEDRPSLSEEPAFE
LDIKYTGESTASKLKRVREAMTDAGTNVHVITSLDDIAWILNIRGNDIEFFPLVLSYLIITMDEAHLFINEDKLSDEIKS
NLKKNGVSFIHPYNEIYKAVKKFNTSDIVLVDPARMNYALYNNIPKDVKKVEKRNPSVLFKAMKNPIEIENIKKAQIKDG
VAHTKFMYWLKHNIGKETITEISASNKLDEFRAEQGEFIRPSFEPISSFAEHAAIVHYAPTPETDVELKEGSLFLTDTGA
GFYEGSTDITRTYALGEVPQIMKDHFTLTVNSNLHLAHAKFLYGCNGMNLDILARAPFWNRNLNFNHGTGHGVGYLMNIH
EAPTGFRWQYRPNETHPFEEGMVITDEPGIYIAGSHGVRIENELLVCKGEQNEYGQFMYFEPISYVPMDLDAINPDLMTA
EEKAWLNEYHESVYNKISPYLTEEEKNWLKEYTRKIS
>Mature_597_residues
MKVSEKLTKLRNLMTEKNIDMYIVPTADFHQSEYVGEHFKARKYITGFSGSAGTAVITKENAGLWTDGRYFLQAGNQLKG
TTVELFKMGEPGVPTIEEYIMNTLSDKGTLGFDGRVVSMVDGQTYEKILSSKNANINYDCDLINDIWEDRPSLSEEPAFE
LDIKYTGESTASKLKRVREAMTDAGTNVHVITSLDDIAWILNIRGNDIEFFPLVLSYLIITMDEAHLFINEDKLSDEIKS
NLKKNGVSFIHPYNEIYKAVKKFNTSDIVLVDPARMNYALYNNIPKDVKKVEKRNPSVLFKAMKNPIEIENIKKAQIKDG
VAHTKFMYWLKHNIGKETITEISASNKLDEFRAEQGEFIRPSFEPISSFAEHAAIVHYAPTPETDVELKEGSLFLTDTGA
GFYEGSTDITRTYALGEVPQIMKDHFTLTVNSNLHLAHAKFLYGCNGMNLDILARAPFWNRNLNFNHGTGHGVGYLMNIH
EAPTGFRWQYRPNETHPFEEGMVITDEPGIYIAGSHGVRIENELLVCKGEQNEYGQFMYFEPISYVPMDLDAINPDLMTA
EEKAWLNEYHESVYNKISPYLTEEEKNWLKEYTRKIS

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI264681563, Length=620, Percent_Identity=36.7741935483871, Blast_Score=394, Evalue=1e-109,
Organism=Homo sapiens, GI264681565, Length=620, Percent_Identity=35.3225806451613, Blast_Score=363, Evalue=1e-100,
Organism=Homo sapiens, GI93141226, Length=605, Percent_Identity=31.5702479338843, Blast_Score=354, Evalue=1e-97,
Organism=Escherichia coli, GI1788728, Length=246, Percent_Identity=28.0487804878049, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17509539, Length=626, Percent_Identity=34.6645367412141, Blast_Score=371, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI25149105, Length=591, Percent_Identity=28.7648054145516, Blast_Score=242, Evalue=5e-64,
Organism=Saccharomyces cerevisiae, GI6322999, Length=656, Percent_Identity=33.0792682926829, Blast_Score=325, Evalue=1e-89,
Organism=Drosophila melanogaster, GI17137632, Length=613, Percent_Identity=33.605220228385, Blast_Score=338, Evalue=7e-93,
Organism=Drosophila melanogaster, GI161078230, Length=615, Percent_Identity=27.3170731707317, Blast_Score=241, Evalue=1e-63,
Organism=Drosophila melanogaster, GI21357287, Length=615, Percent_Identity=27.3170731707317, Blast_Score=241, Evalue=1e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 67985; Mature: 67985

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVSEKLTKLRNLMTEKNIDMYIVPTADFHQSEYVGEHFKARKYITGFSGSAGTAVITKE
CCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHEEECCCCCCCEEEEEEC
NAGLWTDGRYFLQAGNQLKGTTVELFKMGEPGVPTIEEYIMNTLSDKGTLGFDGRVVSMV
CCCCCCCCHHEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEE
DGQTYEKILSSKNANINYDCDLINDIWEDRPSLSEEPAFELDIKYTGESTASKLKRVREA
CCHHHHHHHHCCCCCCEECHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHH
MTDAGTNVHVITSLDDIAWILNIRGNDIEFFPLVLSYLIITMDEAHLFINEDKLSDEIKS
HHHCCCCEEEEEECCCEEEEEEECCCCEEHHHHHHHHHHHEECCCEEEEECHHHHHHHHH
NLKKNGVSFIHPYNEIYKAVKKFNTSDIVLVDPARMNYALYNNIPKDVKKVEKRNPSVLF
HHHHCCCEEECCHHHHHHHHHHCCCCCEEEECCHHHCCHHHCCCHHHHHHHHHCCHHHHH
KAMKNPIEIENIKKAQIKDGVAHTKFMYWLKHNIGKETITEISASNKLDEFRAEQGEFIR
HHHCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHCCCCCCC
PSFEPISSFAEHAAIVHYAPTPETDVELKEGSLFLTDTGAGFYEGSTDITRTYALGEVPQ
CCHHHHHHHHHHCEEEEECCCCCCCCEEECCEEEEEECCCCCCCCCCCCEEEEECCCCHH
IMKDHFTLTVNSNLHLAHAKFLYGCNGMNLDILARAPFWNRNLNFNHGTGHGVGYLMNIH
HHHCCEEEEECCCEEEEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEE
EAPTGFRWQYRPNETHPFEEGMVITDEPGIYIAGSHGVRIENELLVCKGEQNEYGQFMYF
CCCCCCEEEECCCCCCCHHCCEEEECCCCEEEECCCCEEEECCEEEEECCCCCCCCEEEE
EPISYVPMDLDAINPDLMTAEEKAWLNEYHESVYNKISPYLTEEEKNWLKEYTRKIS
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVSEKLTKLRNLMTEKNIDMYIVPTADFHQSEYVGEHFKARKYITGFSGSAGTAVITKE
CCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHEEECCCCCCCEEEEEEC
NAGLWTDGRYFLQAGNQLKGTTVELFKMGEPGVPTIEEYIMNTLSDKGTLGFDGRVVSMV
CCCCCCCCHHEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEE
DGQTYEKILSSKNANINYDCDLINDIWEDRPSLSEEPAFELDIKYTGESTASKLKRVREA
CCHHHHHHHHCCCCCCEECHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHH
MTDAGTNVHVITSLDDIAWILNIRGNDIEFFPLVLSYLIITMDEAHLFINEDKLSDEIKS
HHHCCCCEEEEEECCCEEEEEEECCCCEEHHHHHHHHHHHEECCCEEEEECHHHHHHHHH
NLKKNGVSFIHPYNEIYKAVKKFNTSDIVLVDPARMNYALYNNIPKDVKKVEKRNPSVLF
HHHHCCCEEECCHHHHHHHHHHCCCCCEEEECCHHHCCHHHCCCHHHHHHHHHCCHHHHH
KAMKNPIEIENIKKAQIKDGVAHTKFMYWLKHNIGKETITEISASNKLDEFRAEQGEFIR
HHHCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHCCCCCCC
PSFEPISSFAEHAAIVHYAPTPETDVELKEGSLFLTDTGAGFYEGSTDITRTYALGEVPQ
CCHHHHHHHHHHCEEEEECCCCCCCCEEECCEEEEEECCCCCCCCCCCCEEEEECCCCHH
IMKDHFTLTVNSNLHLAHAKFLYGCNGMNLDILARAPFWNRNLNFNHGTGHGVGYLMNIH
HHHCCEEEEECCCEEEEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEE
EAPTGFRWQYRPNETHPFEEGMVITDEPGIYIAGSHGVRIENELLVCKGEQNEYGQFMYF
CCCCCCEEEECCCCCCCHHCCEEEECCCCEEEECCCCEEEECCEEEEECCCCCCCCEEEE
EPISYVPMDLDAINPDLMTAEEKAWLNEYHESVYNKISPYLTEEEKNWLKEYTRKIS
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]