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The map label for this gene is aspB-1 [H]

Identifier: 153936797

GI number: 153936797

Start: 1851980

End: 1853170

Strand: Direct

Name: aspB-1 [H]

Synonym: CLC_1746

Alternate gene names: 153936797

Gene position: 1851980-1853170 (Clockwise)

Preceding gene: 153935187

Following gene: 153936973

Centisome position: 49.25

GC content: 30.14

Gene sequence:

>1191_bases
ATGAAATTTTCAAAAAGAATATCTGATATGCAATTTTCACCAATAAGAAAGCTTGCACCTTATGCAGCTGAAGCTAAGAG
TAAAGGTATACATGTTTTTCATTTAAACATAGGACAACCAGATATTAAAACTCCAGAATGCTTTGCTGAAGGTGTAAAAT
CTTATGAAGAACCTGTATTAAAATATTCAGATTCTAAAGGTATGGATACTTTATTAGAAAGTTTTATAAAATATTATAAA
CAATGGAATACAACTTTTGATAAAGATGAATTATTAGTAACAAATGGTGGAAGTGAGGCTATTCAATTTGTATTAATGGC
TTTATGTGATGTTGGAGATGAGATTATAATACCAGAACCATTTTATACAAACTATAATGGCTTTGCTGAATCAGCTGGAG
TTAATGTAGTTCCTTTCTTGACAAAAGCAGAAGAAGGATTCCATCTTCCAAAGAAAGAAGAAATAGTAAGCAAAATATCT
GATAAAACAAGAGCAATATTAGTTTCAAATCCAGGAAACCCAACTGGAGTTGTTTATACTTATGAAGAATTAAGAATGCT
TGCAGACATTGCTAAAGAGCATGATTTATTCTTAATTGCAGATGAAGTTTATAGAGAATTCGTATATGATGGATTAAAAT
ATACATCAGCTATGTATCTAGAAGATGTACAAGACAGAGTTATAATAATAGATAGTATATCTAAACGTTACAGTGCTTGT
GGAGCTAGAATAGGACTTGTAGCTTCTAAAAACAGAGAACTTATACATCAAATATTAAAATTATGTCAATCAAGATTATG
TGTTCCTACAGTAGAACAACTTGGAGCAGCTAACTTAATAAATACTCCAGAAAGTTATTTCACAGAAGTAAAAGCTGAAT
ATGAAAACAGACGTAATATAATGTTTGAAGGATTAAAAAATATACCTGGAGTTATATGTGAAAAACCAACAGGAGCTTTT
TACATAGTAGCTAAACTTCCTGTAGATAATGCAGAAGAATTTACTAAATGGATGCTAACTAAGTTTAGTCACAATAATAA
AACTGTTATGGTAGCTCCAGCAGCTGGATTCTACGCAACAGAAGGTTTAGGCGAAGATGAAATAAGACTTTCCTATTGCT
TAAAAGGTGAAGATCTAAAAGAAGCTATGGAAATATTAAAATTAGCTATAGAAAAATATAATAGCAAATAA

Upstream 100 bases:

>100_bases
TAACTTAAAATCAACTTATGTTCCAAGAGAGAATATATTTTATTAAAATTTAAATATATTTATTAAATTTTGAACATTTA
TTAATGGGGGGTAAAAAACA

Downstream 100 bases:

>100_bases
AAAATAACCCTTTTGGGGTTATTTTTTATTTTATGTATTTATTATAAATACATGTTTTTCTTTATATGATAAAAAACCTA
AAGATTTATAAAGATTTAGT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MKFSKRISDMQFSPIRKLAPYAAEAKSKGIHVFHLNIGQPDIKTPECFAEGVKSYEEPVLKYSDSKGMDTLLESFIKYYK
QWNTTFDKDELLVTNGGSEAIQFVLMALCDVGDEIIIPEPFYTNYNGFAESAGVNVVPFLTKAEEGFHLPKKEEIVSKIS
DKTRAILVSNPGNPTGVVYTYEELRMLADIAKEHDLFLIADEVYREFVYDGLKYTSAMYLEDVQDRVIIIDSISKRYSAC
GARIGLVASKNRELIHQILKLCQSRLCVPTVEQLGAANLINTPESYFTEVKAEYENRRNIMFEGLKNIPGVICEKPTGAF
YIVAKLPVDNAEEFTKWMLTKFSHNNKTVMVAPAAGFYATEGLGEDEIRLSYCLKGEDLKEAMEILKLAIEKYNSK

Sequences:

>Translated_396_residues
MKFSKRISDMQFSPIRKLAPYAAEAKSKGIHVFHLNIGQPDIKTPECFAEGVKSYEEPVLKYSDSKGMDTLLESFIKYYK
QWNTTFDKDELLVTNGGSEAIQFVLMALCDVGDEIIIPEPFYTNYNGFAESAGVNVVPFLTKAEEGFHLPKKEEIVSKIS
DKTRAILVSNPGNPTGVVYTYEELRMLADIAKEHDLFLIADEVYREFVYDGLKYTSAMYLEDVQDRVIIIDSISKRYSAC
GARIGLVASKNRELIHQILKLCQSRLCVPTVEQLGAANLINTPESYFTEVKAEYENRRNIMFEGLKNIPGVICEKPTGAF
YIVAKLPVDNAEEFTKWMLTKFSHNNKTVMVAPAAGFYATEGLGEDEIRLSYCLKGEDLKEAMEILKLAIEKYNSK
>Mature_396_residues
MKFSKRISDMQFSPIRKLAPYAAEAKSKGIHVFHLNIGQPDIKTPECFAEGVKSYEEPVLKYSDSKGMDTLLESFIKYYK
QWNTTFDKDELLVTNGGSEAIQFVLMALCDVGDEIIIPEPFYTNYNGFAESAGVNVVPFLTKAEEGFHLPKKEEIVSKIS
DKTRAILVSNPGNPTGVVYTYEELRMLADIAKEHDLFLIADEVYREFVYDGLKYTSAMYLEDVQDRVIIIDSISKRYSAC
GARIGLVASKNRELIHQILKLCQSRLCVPTVEQLGAANLINTPESYFTEVKAEYENRRNIMFEGLKNIPGVICEKPTGAF
YIVAKLPVDNAEEFTKWMLTKFSHNNKTVMVAPAAGFYATEGLGEDEIRLSYCLKGEDLKEAMEILKLAIEKYNSK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=390, Percent_Identity=28.2051282051282, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI56713256, Length=390, Percent_Identity=28.2051282051282, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI95147551, Length=418, Percent_Identity=26.3157894736842, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI169881279, Length=418, Percent_Identity=26.3157894736842, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI4507369, Length=353, Percent_Identity=25.4957507082153, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI169881281, Length=302, Percent_Identity=27.1523178807947, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI149944424, Length=257, Percent_Identity=28.4046692607004, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI4885351, Length=373, Percent_Identity=27.6139410187668, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI187936925, Length=233, Percent_Identity=25.7510729613734, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI14211921, Length=233, Percent_Identity=25.7510729613734, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI215599424, Length=372, Percent_Identity=26.0752688172043, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI19263340, Length=372, Percent_Identity=26.0752688172043, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1788627, Length=323, Percent_Identity=29.7213622291022, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1788722, Length=396, Percent_Identity=25.2525252525253, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786816, Length=379, Percent_Identity=23.4828496042216, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790797, Length=308, Percent_Identity=24.3506493506494, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788332, Length=335, Percent_Identity=23.5820895522388, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787710, Length=303, Percent_Identity=24.0924092409241, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=330, Percent_Identity=28.1818181818182, Blast_Score=125, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI71994472, Length=407, Percent_Identity=27.2727272727273, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71994476, Length=407, Percent_Identity=27.2727272727273, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17567369, Length=399, Percent_Identity=27.3182957393484, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71981209, Length=298, Percent_Identity=24.1610738255034, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=385, Percent_Identity=30.6493506493506, Blast_Score=134, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6323118, Length=363, Percent_Identity=27.2727272727273, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320317, Length=297, Percent_Identity=26.2626262626263, Blast_Score=90, Evalue=7e-19,
Organism=Drosophila melanogaster, GI28573069, Length=397, Percent_Identity=28.9672544080605, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24646114, Length=397, Percent_Identity=28.9672544080605, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI28573067, Length=397, Percent_Identity=28.9672544080605, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI28573065, Length=397, Percent_Identity=28.9672544080605, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI18859735, Length=307, Percent_Identity=25.4071661237785, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24641770, Length=303, Percent_Identity=25.7425742574257, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24641760, Length=303, Percent_Identity=25.7425742574257, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24641768, Length=303, Percent_Identity=25.7425742574257, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24641766, Length=303, Percent_Identity=25.7425742574257, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24641764, Length=303, Percent_Identity=25.7425742574257, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45551451, Length=302, Percent_Identity=26.158940397351, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44707; Mature: 44707

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFSKRISDMQFSPIRKLAPYAAEAKSKGIHVFHLNIGQPDIKTPECFAEGVKSYEEPVL
CCCHHHHCCCCCCHHHHHCCHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
KYSDSKGMDTLLESFIKYYKQWNTTFDKDELLVTNGGSEAIQFVLMALCDVGDEIIIPEP
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEECCC
FYTNYNGFAESAGVNVVPFLTKAEEGFHLPKKEEIVSKISDKTRAILVSNPGNPTGVVYT
CCCCCCCCHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCEEEEE
YEELRMLADIAKEHDLFLIADEVYREFVYDGLKYTSAMYLEDVQDRVIIIDSISKRYSAC
HHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHC
GARIGLVASKNRELIHQILKLCQSRLCVPTVEQLGAANLINTPESYFTEVKAEYENRRNI
CCEEEEEECCCHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHCCHH
MFEGLKNIPGVICEKPTGAFYIVAKLPVDNAEEFTKWMLTKFSHNNKTVMVAPAAGFYAT
HHHHHHCCCCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHC
EGLGEDEIRLSYCLKGEDLKEAMEILKLAIEKYNSK
CCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKFSKRISDMQFSPIRKLAPYAAEAKSKGIHVFHLNIGQPDIKTPECFAEGVKSYEEPVL
CCCHHHHCCCCCCHHHHHCCHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
KYSDSKGMDTLLESFIKYYKQWNTTFDKDELLVTNGGSEAIQFVLMALCDVGDEIIIPEP
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEECCC
FYTNYNGFAESAGVNVVPFLTKAEEGFHLPKKEEIVSKISDKTRAILVSNPGNPTGVVYT
CCCCCCCCHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCEEEEE
YEELRMLADIAKEHDLFLIADEVYREFVYDGLKYTSAMYLEDVQDRVIIIDSISKRYSAC
HHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHC
GARIGLVASKNRELIHQILKLCQSRLCVPTVEQLGAANLINTPESYFTEVKAEYENRRNI
CCEEEEEECCCHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHCCHH
MFEGLKNIPGVICEKPTGAFYIVAKLPVDNAEEFTKWMLTKFSHNNKTVMVAPAAGFYAT
HHHHHHCCCCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHC
EGLGEDEIRLSYCLKGEDLKEAMEILKLAIEKYNSK
CCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]