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The map label for this gene is ribB

Identifier: 153936783

GI number: 153936783

Start: 2979982

End: 2980623

Strand: Direct

Name: ribB

Synonym: CLC_2815

Alternate gene names: 153936783

Gene position: 2979982-2980623 (Clockwise)

Preceding gene: 153934489

Following gene: 153934702

Centisome position: 79.24

GC content: 36.14

Gene sequence:

>642_bases
ATGAATGAATCACTATTAACTCAGTTTGGTAATTCTTTAACCCGTGTAGAAAAAGCATTAGAGAATCTAAAAAATGGGAA
AGGAGTACTTCTCGTTGATGATGAAAATCGTGAAAATGAAGGAGATCTTATTTTCCCTGCTGAAACTATCACAGTACCTC
AAATGGTTATGTTAATAAGAGAATGTAGCGGTATTGTTTGCCTTTGCTTAACAGATAAAAAAGTAAAAAAATTAGGTTTA
ACTCAAATGGTACATAATAATACATGTACGTACGAAACTGCATTTACTATCTCAATTGAAGCTAAAGAAGGGGTAACTAC
CGGGGTTTCCGCTGCGGATAGAGTTACTACCATTCTTACTGCGGTAAAAGATGATTGTAAACCTGAAGACTTATGTCATC
CCGGCCATGTTTTCCCACTTCGTGCCCGTGCAGGAGGTGTTTTAACTAGACCTGGCCATACAGAAGGTACCGTTGACCTT
ATGCGTTTGGCAGGATATAATCCTGCAGGAATTTTGTGCGAACTTACAAATCCTGATGGAACCATGGCTCGTCTACCACA
AATAATTAATTTTGCTAAAAAACATAATTTAGCCGTTCTTTCCATTGAGGATATTATAAAATATAAAAAAATTACTACTT
AA

Upstream 100 bases:

>100_bases
CCTTAACTTCTTACATAATGATTAGTGTTTAAAGCATCATTATATAATAAAAAACTGAAGTGCTTTATGTAAATTTTTTC
ATAGTTTGGAGGAATTTTAA

Downstream 100 bases:

>100_bases
AAGGAAATTATTATAACAGCCTTTAAAGGTATTAAAACAAAAAATACTTTTAGTGAAAAGAGATATCTAGAAAAATAATA
AGAATACTTTATTTGTGAAC

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MNESLLTQFGNSLTRVEKALENLKNGKGVLLVDDENRENEGDLIFPAETITVPQMVMLIRECSGIVCLCLTDKKVKKLGL
TQMVHNNTCTYETAFTISIEAKEGVTTGVSAADRVTTILTAVKDDCKPEDLCHPGHVFPLRARAGGVLTRPGHTEGTVDL
MRLAGYNPAGILCELTNPDGTMARLPQIINFAKKHNLAVLSIEDIIKYKKITT

Sequences:

>Translated_213_residues
MNESLLTQFGNSLTRVEKALENLKNGKGVLLVDDENRENEGDLIFPAETITVPQMVMLIRECSGIVCLCLTDKKVKKLGL
TQMVHNNTCTYETAFTISIEAKEGVTTGVSAADRVTTILTAVKDDCKPEDLCHPGHVFPLRARAGGVLTRPGHTEGTVDL
MRLAGYNPAGILCELTNPDGTMARLPQIINFAKKHNLAVLSIEDIIKYKKITT
>Mature_213_residues
MNESLLTQFGNSLTRVEKALENLKNGKGVLLVDDENRENEGDLIFPAETITVPQMVMLIRECSGIVCLCLTDKKVKKLGL
TQMVHNNTCTYETAFTISIEAKEGVTTGVSAADRVTTILTAVKDDCKPEDLCHPGHVFPLRARAGGVLTRPGHTEGTVDL
MRLAGYNPAGILCELTNPDGTMARLPQIINFAKKHNLAVLSIEDIIKYKKITT

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family

Homologues:

Organism=Escherichia coli, GI1789420, Length=210, Percent_Identity=63.3333333333333, Blast_Score=292, Evalue=1e-80,
Organism=Saccharomyces cerevisiae, GI6320695, Length=206, Percent_Identity=41.2621359223301, Blast_Score=160, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RIBB_CLOB1 (A7FXH7)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001385181.1
- ProteinModelPortal:   A7FXH7
- SMR:   A7FXH7
- STRING:   A7FXH7
- GeneID:   5395338
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_2882
- eggNOG:   COG0108
- HOGENOM:   HBG735778
- OMA:   RGHTEAT
- ProtClustDB:   CLSK941046
- BioCyc:   CBOT441770:CLB_2882-MONOMER
- HAMAP:   MF_00180
- InterPro:   IPR017945
- InterPro:   IPR000422
- Gene3D:   G3DSA:3.90.870.10
- TIGRFAMs:   TIGR00506

Pfam domain/function: PF00926 DHBP_synthase; SSF55821 DHBP_synth_RibB-like_a/b_dom

EC number: =4.1.99.12

Molecular weight: Translated: 23266; Mature: 23266

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: BINDING 42-42 BINDING 174-174

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNESLLTQFGNSLTRVEKALENLKNGKGVLLVDDENRENEGDLIFPAETITVPQMVMLIR
CCHHHHHHHCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEECHHHCCHHHHHHHHH
ECSGIVCLCLTDKKVKKLGLTQMVHNNTCTYETAFTISIEAKEGVTTGVSAADRVTTILT
HCCCEEEEEECCHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHH
AVKDDCKPEDLCHPGHVFPLRARAGGVLTRPGHTEGTVDLMRLAGYNPAGILCELTNPDG
HHHCCCCCCCCCCCCCEEEEECCCCCEEECCCCCCCHHHHHHHCCCCCCCEEEEEECCCC
TMARLPQIINFAKKHNLAVLSIEDIIKYKKITT
HHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCC
>Mature Secondary Structure
MNESLLTQFGNSLTRVEKALENLKNGKGVLLVDDENRENEGDLIFPAETITVPQMVMLIR
CCHHHHHHHCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEECHHHCCHHHHHHHHH
ECSGIVCLCLTDKKVKKLGLTQMVHNNTCTYETAFTISIEAKEGVTTGVSAADRVTTILT
HCCCEEEEEECCHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHH
AVKDDCKPEDLCHPGHVFPLRARAGGVLTRPGHTEGTVDLMRLAGYNPAGILCELTNPDG
HHHCCCCCCCCCCCCCEEEEECCCCCEEECCCCCCCHHHHHHHCCCCCCCEEEEEECCCC
TMARLPQIINFAKKHNLAVLSIEDIIKYKKITT
HHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA