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The map label for this gene is ubiE [C]

Identifier: 153936712

GI number: 153936712

Start: 833280

End: 834086

Strand: Direct

Name: ubiE [C]

Synonym: CLC_0814

Alternate gene names: 153936712

Gene position: 833280-834086 (Clockwise)

Preceding gene: 153934633

Following gene: 153934744

Centisome position: 22.16

GC content: 31.6

Gene sequence:

>807_bases
ATGAGTAATTCTAAAAAGATAAGTAATTTTAAAAAGGTAGATGTTAGAAATGCTGTTCGTAATAGTTATAGAAAAATAGC
TATTGGAAATGCAAAAGAGGATGGCTGCTGTGGTGGAAGTATTAATCTTAAAAAATCTTCCATAGAGATATCACGTAAAA
TTGGATATTCTGATGAAGAAATATCAACTGTTCCACAGGAAGCTAATATGGGGTTAGGTTGTGGAAATCCTCAATTAATA
GCTAATATTAAAGAAGGCGAAACTGTTATAGACCTTGGAAGTGGAGGCGGATTTGACTGTTTCTTAGCCTCAAAGAAAGT
TGGGTCTAAGGGATATATTATTGGAGTTGACATGACTCCAGAGATGATTAGTAAATCAAGAATTATGTCTAGGAAATATA
GGTATAGAAATGTAGACTTTAGATTAGGTGAAATTGAAAATCTTCCTGTAGCAGATAATACTGCGGATGTAATTATTTCA
AATTGTGTTATAAATTTATCTCCCAATAAACAAAGAGTATATAATGAAGCTTATCGTGTATTAAAAAAAGGTGGTAGAGT
TGCTATTTCTGATATAGTTCTTATTAGAGAATTGACTAAGGAAATGAAGCAAGATGAGAAACTTTATTGTGGATGAGTGA
CTGGGGCATCTTCAGTTGAAGAATTGAAATTATATTTAGAAAAGGCTGGTTTTAGTGATATTAGAATTGACACTCAAGAA
GTCTCAAAGGAATATGCTGAAAAATGGGGACATAACTTAAAAGTTGGAGAATATATTATGTCCGCATCAATAAAAGCAAT
AAAATAA

Upstream 100 bases:

>100_bases
ATAATTAAATTGCATTAAGATGATGATAAAATTTTATGGCTTTTATTTATCACTGGATAGTTAAAGTAGGGAGGGAAAAA
AGATGAGCGATTTAAAAAAG

Downstream 100 bases:

>100_bases
CAATTTAAAAGGAGTAGAAAAAATTTTTCTGCTCCTTTTGCAGAGCTTCAAAACTTATAGTTTTGAAGCTCTTATAATAT
CTTTAGACTAGCTATTTTTT

Product: UbiE/COQ5 family methlytransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: Arsenite S-Adenosylmethyltransferase; Methyltransferase; Arsenite Methyltransferase; SAM-Dependent Methyltransferase; UbiE/COQ5 Methyltransferase; Transcriptional Regulator ArsR Family; Methyltransferase Domain Family; Methyltransferase-Like; ArsR Family Transcriptional Regulator; UbiE/COQ5 Family Methlytransferase; Ubiquinone/Menaquinone Biosynthesis Methyltransferase UbiE; Arsenic Methyltransferase; 2-Heptaprenyl-1 4-Naphthoquinone Methyltransferase; Protein Containing Methyltransferase Domain; Transcriptional Regulator; SAM-Dependent Methyltransferases; Cyclopropane-Fatty-Acyl-Phospholipid Synthase; Methyltransferase UbiE/COQ5 Family; Methyltransferase UbiE-Family; Radical SAM Domain-Containing Protein; Methyltransferase Domain Family Protein

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MSNSKKISNFKKVDVRNAVRNSYRKIAIGNAKEDGCCGGSINLKKSSIEISRKIGYSDEEISTVPQEANMGLGCGNPQLI
ANIKEGETVIDLGSGGGFDCFLASKKVGSKGYIIGVDMTPEMISKSRIMSRKYRYRNVDFRLGEIENLPVADNTADVIIS
NCVINLSPNKQRVYNEAYRVLKKGGRVAISDIVLIRELTKEMKQDEKLYCGUVTGASSVEELKLYLEKAGFSDIRIDTQE
VSKEYAEKWGHNLKVGEYIMSASIKAIK

Sequences:

>Translated_268_residues
MSNSKKISNFKKVDVRNAVRNSYRKIAIGNAKEDGCCGGSINLKKSSIEISRKIGYSDEEISTVPQEANMGLGCGNPQLI
ANIKEGETVIDLGSGGGFDCFLASKKVGSKGYIIGVDMTPEMISKSRIMSRKYRYRNVDFRLGEIENLPVADNTADVIIS
NCVINLSPNKQRVYNEAYRVLKKGGRVAISDIVLIRELTKEMKQDEKLYCG*VTGASSVEELKLYLEKAGFSDIRIDTQE
VSKEYAEKWGHNLKVGEYIMSASIKAIK
>Mature_267_residues
SNSKKISNFKKVDVRNAVRNSYRKIAIGNAKEDGCCGGSINLKKSSIEISRKIGYSDEEISTVPQEANMGLGCGNPQLIA
NIKEGETVIDLGSGGGFDCFLASKKVGSKGYIIGVDMTPEMISKSRIMSRKYRYRNVDFRLGEIENLPVADNTADVIISN
CVINLSPNKQRVYNEAYRVLKKGGRVAISDIVLIRELTKEMKQDEKLYCG*VTGASSVEELKLYLEKAGFSDIRIDTQEV
SKEYAEKWGHNLKVGEYIMSASIKAIK

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI109389364, Length=176, Percent_Identity=39.2045454545455, Blast_Score=108, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 29510; Mature: 29379

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSKKISNFKKVDVRNAVRNSYRKIAIGNAKEDGCCGGSINLKKSSIEISRKIGYSDEE
CCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCEEEHHHEEHHHHCCCCCHH
ISTVPQEANMGLGCGNPQLIANIKEGETVIDLGSGGGFDCFLASKKVGSKGYIIGVDMTP
HHCCCCCCCCCCCCCCCCEEEEECCCCEEEEECCCCCEEEEEECCCCCCCCEEEEECCCH
EMISKSRIMSRKYRYRNVDFRLGEIENLPVADNTADVIISNCVINLSPNKQRVYNEAYRV
HHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHEEEEEEEEEECCCHHHHHHHHHHH
LKKGGRVAISDIVLIRELTKEMKQDEKLYCGVTGASSVEELKLYLEKAGFSDIRIDTQEV
HHCCCCEEHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCCEEECHHHH
SKEYAEKWGHNLKVGEYIMSASIKAIK
HHHHHHHCCCCCCHHHHHHHCCCEECC
>Mature Secondary Structure 
SNSKKISNFKKVDVRNAVRNSYRKIAIGNAKEDGCCGGSINLKKSSIEISRKIGYSDEE
CCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCEEEHHHEEHHHHCCCCCHH
ISTVPQEANMGLGCGNPQLIANIKEGETVIDLGSGGGFDCFLASKKVGSKGYIIGVDMTP
HHCCCCCCCCCCCCCCCCEEEEECCCCEEEEECCCCCEEEEEECCCCCCCCEEEEECCCH
EMISKSRIMSRKYRYRNVDFRLGEIENLPVADNTADVIISNCVINLSPNKQRVYNEAYRV
HHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHEEEEEEEEEECCCHHHHHHHHHHH
LKKGGRVAISDIVLIRELTKEMKQDEKLYCGVTGASSVEELKLYLEKAGFSDIRIDTQEV
HHCCCCEEHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCCEEECHHHH
SKEYAEKWGHNLKVGEYIMSASIKAIK
HHHHHHHCCCCCCHHHHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA