Click here to switch to the map view.

The map label for this gene is dapH

Identifier: 153936442

GI number: 153936442

Start: 3231795

End: 3232505

Strand: Direct

Name: dapH

Synonym: CLC_3065

Alternate gene names: 153936442

Gene position: 3231795-3232505 (Clockwise)

Preceding gene: 153934891

Following gene: 153937680

Centisome position: 85.94

GC content: 32.63

Gene sequence:

>711_bases
ATGAGTTACAATCTAACAGATCCGTATGAAATAGCTAGATACATAAAAGAAGCCAAAAAATCGACTCCTATCAAAGCTTA
CATAGAAGGAGATCTTTCAAACTGTGATTTTACGAACATAGAAAAATTTAATAGTGGAGATTTATATATATTATTTGGTG
AATCAGAAGAAATATTAGTTATTATAGAAAAAAATAAAGATAAAATAAAAAATTGTAGAATAGAACAGGATAGAAGAAAG
TCTGCAATTCCTTTACTTGATATGCTTAAAATAAATGCTAGAATAGAGCCAGGTGCTACAATAAGAGATAAAGTTATAAT
AGGAGAAAATGCTGTTATTATGATGGGCGCCGTTGTAAATATAGGTGCTGAAATCGGAGAAGGAACTATGGTAGATATGA
ACGCTGTAGTTGGCGCTAGAGGAAAACTTGGTAAAAATGTACATTTAGGTGCTGGTGCTGTAGTTGCTGGTGTTTTAGAA
CCACCTAGCAGTGATCCTTGTACTATAGAGGATAATGTTCTTATAGGCGCAAATGCTGTTATATTAGAAGGTGTAAAAAT
TGGTAAAGGTTCTGTAGTGGCAGCAGGGTCTATAGTTACTACTGATGTACCAGAAAACGTAGTAGTGGCTGGTGCTCCAG
CTAAAATAATAAAAGAAGTAGATGTAAAAACTAAAGATAAAACTAAGCTTTTAGATGATTTAAGAAAATAA

Upstream 100 bases:

>100_bases
TACTTATTATACTATTATTTTCATGTATATTAAATACCCCCTTTATTTAAACATCAATATTTATTATAATAGTGTTATTA
TAAAATAAGGAGGAAATATA

Downstream 100 bases:

>100_bases
ATTTATGAAAGATAGTTTTAAAACTATCTTTCATATTTGATAAAGTTTTCTATTAATTTATTTAAATATACTTGAGAATA
GTATGTACAACTTAAAAAGT

Product: putative 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-acetyltransferase; THP acetyltransferase; Tetrahydropicolinate acetylase

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSYNLTDPYEIARYIKEAKKSTPIKAYIEGDLSNCDFTNIEKFNSGDLYILFGESEEILVIIEKNKDKIKNCRIEQDRRK
SAIPLLDMLKINARIEPGATIRDKVIIGENAVIMMGAVVNIGAEIGEGTMVDMNAVVGARGKLGKNVHLGAGAVVAGVLE
PPSSDPCTIEDNVLIGANAVILEGVKIGKGSVVAAGSIVTTDVPENVVVAGAPAKIIKEVDVKTKDKTKLLDDLRK

Sequences:

>Translated_236_residues
MSYNLTDPYEIARYIKEAKKSTPIKAYIEGDLSNCDFTNIEKFNSGDLYILFGESEEILVIIEKNKDKIKNCRIEQDRRK
SAIPLLDMLKINARIEPGATIRDKVIIGENAVIMMGAVVNIGAEIGEGTMVDMNAVVGARGKLGKNVHLGAGAVVAGVLE
PPSSDPCTIEDNVLIGANAVILEGVKIGKGSVVAAGSIVTTDVPENVVVAGAPAKIIKEVDVKTKDKTKLLDDLRK
>Mature_235_residues
SYNLTDPYEIARYIKEAKKSTPIKAYIEGDLSNCDFTNIEKFNSGDLYILFGESEEILVIIEKNKDKIKNCRIEQDRRKS
AIPLLDMLKINARIEPGATIRDKVIIGENAVIMMGAVVNIGAEIGEGTMVDMNAVVGARGKLGKNVHLGAGAVVAGVLEP
PSSDPCTIEDNVLIGANAVILEGVKIGKGSVVAAGSIVTTDVPENVVVAGAPAKIIKEVDVKTKDKTKLLDDLRK

Specific function: Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. DapH subfamily

Homologues:

Organism=Escherichia coli, GI1786362, Length=169, Percent_Identity=39.6449704142012, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786537, Length=72, Percent_Identity=48.6111111111111, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786664, Length=55, Percent_Identity=60, Blast_Score=63, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322243, Length=118, Percent_Identity=37.2881355932203, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPH_CLOB1 (A7FYA5)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001385478.1
- ProteinModelPortal:   A7FYA5
- SMR:   A7FYA5
- STRING:   A7FYA5
- GeneID:   5394999
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_3191
- eggNOG:   COG2171
- HOGENOM:   HBG704071
- OMA:   KNAVIMM
- ProtClustDB:   CLSK883132
- BioCyc:   CBOT441770:CLB_3191-MONOMER
- HAMAP:   MF_01691
- InterPro:   IPR013710
- InterPro:   IPR018357
- InterPro:   IPR019873
- InterPro:   IPR011004
- TIGRFAMs:   TIGR03532

Pfam domain/function: PF08503 DapD_N; SSF51161 Trimer_LpxA_like

EC number: =2.3.1.89

Molecular weight: Translated: 25290; Mature: 25159

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYNLTDPYEIARYIKEAKKSTPIKAYIEGDLSNCDFTNIEKFNSGDLYILFGESEEILV
CCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEECCCCCEEEEECCCCCEEE
IIEKNKDKIKNCRIEQDRRKSAIPLLDMLKINARIEPGATIRDKVIIGENAVIMMGAVVN
EEECCCCHHHCCCCCCHHHHCCCCEEEEEEECCEECCCCCEEEEEEECCCCEEEEEEHEE
IGAEIGEGTMVDMNAVVGARGKLGKNVHLGAGAVVAGVLEPPSSDPCTIEDNVLIGANAV
CCCCCCCCEEEEEHHEECCCCCCCCEEEECCCEEEEEEECCCCCCCCEEECCEEECCCEE
ILEGVKIGKGSVVAAGSIVTTDVPENVVVAGAPAKIIKEVDVKTKDKTKLLDDLRK
EEECEEECCCCEEEECCEEEECCCCCEEEECCCHHHHHHCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SYNLTDPYEIARYIKEAKKSTPIKAYIEGDLSNCDFTNIEKFNSGDLYILFGESEEILV
CCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEECCCCCEEEEECCCCCEEE
IIEKNKDKIKNCRIEQDRRKSAIPLLDMLKINARIEPGATIRDKVIIGENAVIMMGAVVN
EEECCCCHHHCCCCCCHHHHCCCCEEEEEEECCEECCCCCEEEEEEECCCCEEEEEEHEE
IGAEIGEGTMVDMNAVVGARGKLGKNVHLGAGAVVAGVLEPPSSDPCTIEDNVLIGANAV
CCCCCCCCEEEEEHHEECCCCCCCCEEEECCCEEEEEEECCCCCCCCEEECCEEECCCEE
ILEGVKIGKGSVVAAGSIVTTDVPENVVVAGAPAKIIKEVDVKTKDKTKLLDDLRK
EEECEEECCCCEEEECCEEEECCCCCEEEECCCHHHHHHCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA