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The map label for this gene is prdA [H]

Identifier: 153935965

GI number: 153935965

Start: 2440493

End: 2442607

Strand: Reverse

Name: prdA [H]

Synonym: CLC_2313

Alternate gene names: 153935965

Gene position: 2442607-2440493 (Counterclockwise)

Preceding gene: 153934616

Following gene: 153936255

Centisome position: 64.95

GC content: 34.37

Gene sequence:

>2115_bases
ATGTCAATGACACCAGAGCATGCAGAGGCGTTAAAGAATGAATCTGCAGTAGTATGTTGTAGAGCAGAAGAGGGAACAAT
ATTAACTGCTGACAACTTAGAAGATCCAGAAATATTCCCAGATATGGTAGACTCAGGTCTATTAACTATTCCAGCTGATT
GTTTAAAAGTTGGGGAAGTAATAGGAGCTAAATTGTTAAAAACTGTAGATTCATTAACACCATTAACTCCAGATATAATT
GAGGGAGCAAAAACAATAGGTGGTTCAGAAGAAAAGGCTGAAGAAAATTCAGAAGAATTAACTGAAGAAGATGAAAAAGC
AGTTCTAAAATATAACTTAAAAGCAGGAGATACTATAAAAGCTAGTGATCTAGAAAATCCAATGCATTTTGAAAAACTTG
TAGATTCTCTTTTACTAACATTAGATGAAAGAGTTCTTACAAGAAAAGAAGTAGTTGGAGCAACTTTATCAGTTGATACG
CCAGCTTTAACTCCTGTAACACCTGATATATTAGAAGGATTTGAGGAGGAAGTAAACATGAGTGCTGATACACAAGCAAC
AATAAGTGGTGGAACTTTAAGAATCAGAATAGCCGAAGGAAAAGGAATTGACATCGAAGTTCCTTTAAATGGAAATGTAG
GTGCAGGAAAATCAATAGCTGTTCCAGCAGTAAAAGCTGAAAAAGGCACAGTAACTGCAGCGCCAGTAGCAGTAGAAGCT
AAAAAAGAAGTTAAATTAGAAGAAAAAATAGTAAGATCAGTTACAAGAAAACACTATAAAATAGATAAAGTAGAATTAGC
TAAAGAAACTAAAATTGAAGGAACAACTCTTTATATAAGAGAAAACATCTGTGAAGATGCATTCAATGTAGACCAATTAG
TTAAAGATATAAAATTAGAAATAATAACTCCAGATAAGTACAACACTTATAGTGAAACTATAATGGACGTACAACCAATA
GCTACTAAAGAAGGTTCAGATGCTAAGTTAGGTGAAGGTGTTACAAGAGTTATAGATGGAGCTATTGTAATGGTAACTGG
CATAGATGAAGACGGAGTTCAAGTTGGTGAATTCGGTTCTTCAGAAGGTATATTAGAAGAAAACATTATGTGGGGAAGAC
CAGGTGCTCCTGATAAAGGTGAAATATTCATCAAAACTCAAGTAACTATAAAAAGAGGAACAGGAATGGAAAGACCAGGT
CCATTAGCTGCTCACAAAGCAACAGATTTTATAACTCAAGAAATCAGAGAAGCTTTAAAAGATGTTGAAGATGATTCATT
AGTAGTTAACACTGAAACTTTTGAACAAGTAAGAAGACCAGGAAAGAAAAAAGTTGTAGTTGTTAAAGAAATAATGGGTC
AAGGTGCTATGCACGATAACTTAATATTACCATTAGAACCAGTTGGGGTAATAGGAGCTAAACCAAACGTTGATTTAGGA
AACGTTCCAGTAATGCTTGCGCCAACAGAAGTATTAGATGGTGGTATCCATGCATTAACTTGTATTGGACCTGCTTCTAA
AGAATGTTCAAGACACTACTTTAGAGAACCACTTGTAATGGAATGTATGCAAGATGAAGAAGTAGATTTAGCAGGAGTTA
TATTTGTAGGAAGTCCACAAATCAACAGTGAAAAATTCTATGTATCTGAAAGATTAGGTATGATGGTAGAAGCTATGGAT
GTTGATGGTGCTTTTGTTACAACTGAAGGTTTTGGAAATAACCACATTGACTTTGCAAGCCACGTAGAACAAATAGGTAT
GAGAGGTGTTCCTTGTGTAGCATTCTCATTCTGCGCAGTTCAAGGCGCTCTAGTTGTTGGTAACAAACACATGAAATATA
TGGTAGATAACAACAAATCAGAAGGTGGAATAGAAAACGAAGTATTATCTTGTAATACATTATGTAAAGAAGATGCTGTA
AGAGGCCTTGCAATGATTAAAGCAGCTATGTCTGGAGAAGAAGTTAAAAAGCCAGAAAGAGCTTGGAATGCAAATGTTAA
AGAAAATAACATTGAAATGATAGAAAAATCTACTGGAAATAAAATTGATAGAGTTTTAAATGAAACTTCAATACCAATGA
GCGAAAAGAGAAAAGAAAAATACACTACAAAGTAG

Upstream 100 bases:

>100_bases
ATCATCATACTGATCATATATTTAGAACTATTGATTACACATTAACAAGAAGACTTCCACAGGAATAACAAAAAAATAAA
AAAATAGGAGGTTATGTCTT

Downstream 100 bases:

>100_bases
GGATATAGATGGATTTAAAATATGGTGATAAAATCCTAGAAATGCAAGGTGTTATTGTAGACGTATCCGATGGAGCAGTA
GCCATAGATTTCAAAGGAAG

Product: putative D-proline reductase, PrdA proprotein

Products: NA

Alternate protein names: D-proline reductase 45 kDa subunit; D-proline reductase 23 kDa subunit [H]

Number of amino acids: Translated: 704; Mature: 703

Protein sequence:

>704_residues
MSMTPEHAEALKNESAVVCCRAEEGTILTADNLEDPEIFPDMVDSGLLTIPADCLKVGEVIGAKLLKTVDSLTPLTPDII
EGAKTIGGSEEKAEENSEELTEEDEKAVLKYNLKAGDTIKASDLENPMHFEKLVDSLLLTLDERVLTRKEVVGATLSVDT
PALTPVTPDILEGFEEEVNMSADTQATISGGTLRIRIAEGKGIDIEVPLNGNVGAGKSIAVPAVKAEKGTVTAAPVAVEA
KKEVKLEEKIVRSVTRKHYKIDKVELAKETKIEGTTLYIRENICEDAFNVDQLVKDIKLEIITPDKYNTYSETIMDVQPI
ATKEGSDAKLGEGVTRVIDGAIVMVTGIDEDGVQVGEFGSSEGILEENIMWGRPGAPDKGEIFIKTQVTIKRGTGMERPG
PLAAHKATDFITQEIREALKDVEDDSLVVNTETFEQVRRPGKKKVVVVKEIMGQGAMHDNLILPLEPVGVIGAKPNVDLG
NVPVMLAPTEVLDGGIHALTCIGPASKECSRHYFREPLVMECMQDEEVDLAGVIFVGSPQINSEKFYVSERLGMMVEAMD
VDGAFVTTEGFGNNHIDFASHVEQIGMRGVPCVAFSFCAVQGALVVGNKHMKYMVDNNKSEGGIENEVLSCNTLCKEDAV
RGLAMIKAAMSGEEVKKPERAWNANVKENNIEMIEKSTGNKIDRVLNETSIPMSEKRKEKYTTK

Sequences:

>Translated_704_residues
MSMTPEHAEALKNESAVVCCRAEEGTILTADNLEDPEIFPDMVDSGLLTIPADCLKVGEVIGAKLLKTVDSLTPLTPDII
EGAKTIGGSEEKAEENSEELTEEDEKAVLKYNLKAGDTIKASDLENPMHFEKLVDSLLLTLDERVLTRKEVVGATLSVDT
PALTPVTPDILEGFEEEVNMSADTQATISGGTLRIRIAEGKGIDIEVPLNGNVGAGKSIAVPAVKAEKGTVTAAPVAVEA
KKEVKLEEKIVRSVTRKHYKIDKVELAKETKIEGTTLYIRENICEDAFNVDQLVKDIKLEIITPDKYNTYSETIMDVQPI
ATKEGSDAKLGEGVTRVIDGAIVMVTGIDEDGVQVGEFGSSEGILEENIMWGRPGAPDKGEIFIKTQVTIKRGTGMERPG
PLAAHKATDFITQEIREALKDVEDDSLVVNTETFEQVRRPGKKKVVVVKEIMGQGAMHDNLILPLEPVGVIGAKPNVDLG
NVPVMLAPTEVLDGGIHALTCIGPASKECSRHYFREPLVMECMQDEEVDLAGVIFVGSPQINSEKFYVSERLGMMVEAMD
VDGAFVTTEGFGNNHIDFASHVEQIGMRGVPCVAFSFCAVQGALVVGNKHMKYMVDNNKSEGGIENEVLSCNTLCKEDAV
RGLAMIKAAMSGEEVKKPERAWNANVKENNIEMIEKSTGNKIDRVLNETSIPMSEKRKEKYTTK
>Mature_703_residues
SMTPEHAEALKNESAVVCCRAEEGTILTADNLEDPEIFPDMVDSGLLTIPADCLKVGEVIGAKLLKTVDSLTPLTPDIIE
GAKTIGGSEEKAEENSEELTEEDEKAVLKYNLKAGDTIKASDLENPMHFEKLVDSLLLTLDERVLTRKEVVGATLSVDTP
ALTPVTPDILEGFEEEVNMSADTQATISGGTLRIRIAEGKGIDIEVPLNGNVGAGKSIAVPAVKAEKGTVTAAPVAVEAK
KEVKLEEKIVRSVTRKHYKIDKVELAKETKIEGTTLYIRENICEDAFNVDQLVKDIKLEIITPDKYNTYSETIMDVQPIA
TKEGSDAKLGEGVTRVIDGAIVMVTGIDEDGVQVGEFGSSEGILEENIMWGRPGAPDKGEIFIKTQVTIKRGTGMERPGP
LAAHKATDFITQEIREALKDVEDDSLVVNTETFEQVRRPGKKKVVVVKEIMGQGAMHDNLILPLEPVGVIGAKPNVDLGN
VPVMLAPTEVLDGGIHALTCIGPASKECSRHYFREPLVMECMQDEEVDLAGVIFVGSPQINSEKFYVSERLGMMVEAMDV
DGAFVTTEGFGNNHIDFASHVEQIGMRGVPCVAFSFCAVQGALVVGNKHMKYMVDNNKSEGGIENEVLSCNTLCKEDAVR
GLAMIKAAMSGEEVKKPERAWNANVKENNIEMIEKSTGNKIDRVLNETSIPMSEKRKEKYTTK

Specific function: D-proline reductase catalyzes the reductive cleavage of a C-N bond in D-proline resulting in the formation of 5- aminovalerate. The alpha subunit has been shown to bind D-proline, presumably via the pyruvoyl group [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015417 [H]

Pfam domain/function: PF09338 Gly_reductase [H]

EC number: =1.21.4.1 [H]

Molecular weight: Translated: 76457; Mature: 76326

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMTPEHAEALKNESAVVCCRAEEGTILTADNLEDPEIFPDMVDSGLLTIPADCLKVGEV
CCCCHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCCCCHHHHCCCCEECCHHHHHHHHH
IGAKLLKTVDSLTPLTPDIIEGAKTIGGSEEKAEENSEELTEEDEKAVLKYNLKAGDTIK
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHCCHHHHHHHHCCEEEEEECCCCCEEE
ASDLENPMHFEKLVDSLLLTLDERVLTRKEVVGATLSVDTPALTPVTPDILEGFEEEVNM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHHCCC
SADTQATISGGTLRIRIAEGKGIDIEVPLNGNVGAGKSIAVPAVKAEKGTVTAAPVAVEA
CCCCEEEECCCEEEEEEECCCCEEEEEECCCCCCCCCEEECCEEECCCCCEEECCEEECC
KKEVKLEEKIVRSVTRKHYKIDKVELAKETKIEGTTLYIRENICEDAFNVDQLVKDIKLE
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEEHHHHHHHCCHHHHHHHCEEE
IITPDKYNTYSETIMDVQPIATKEGSDAKLGEGVTRVIDGAIVMVTGIDEDGVQVGEFGS
EECCCCCCCHHHHHHCCCCCCCCCCCCCCHHCCHHHHHCCEEEEEECCCCCCCEECCCCC
SEGILEENIMWGRPGAPDKGEIFIKTQVTIKRGTGMERPGPLAAHKATDFITQEIREALK
CCCCCCCCCEECCCCCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
DVEDDSLVVNTETFEQVRRPGKKKVVVVKEIMGQGAMHDNLILPLEPVGVIGAKPNVDLG
CCCCCCEEEEHHHHHHHHCCCCCEEEEEHHHHCCCCCCCCEEEECCCCEEECCCCCCCCC
NVPVMLAPTEVLDGGIHALTCIGPASKECSRHYFREPLVMECMQDEEVDLAGVIFVGSPQ
CCCEEEECHHHHCCCCEEEEEECCCHHHHHHHHHCCCHHHHHCCCCCCCEEEEEEECCCC
INSEKFYVSERLGMMVEAMDVDGAFVTTEGFGNNHIDFASHVEQIGMRGVPCVAFSFCAV
CCCCEEEHHHHHCCEEEEEECCCEEEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHH
QGALVVGNKHMKYMVDNNKSEGGIENEVLSCNTLCKEDAVRGLAMIKAAMSGEEVKKPER
CCEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHH
AWNANVKENNIEMIEKSTGNKIDRVLNETSIPMSEKRKEKYTTK
HHCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
SMTPEHAEALKNESAVVCCRAEEGTILTADNLEDPEIFPDMVDSGLLTIPADCLKVGEV
CCCHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCCCCHHHHCCCCEECCHHHHHHHHH
IGAKLLKTVDSLTPLTPDIIEGAKTIGGSEEKAEENSEELTEEDEKAVLKYNLKAGDTIK
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHCCHHHHHHHHCCEEEEEECCCCCEEE
ASDLENPMHFEKLVDSLLLTLDERVLTRKEVVGATLSVDTPALTPVTPDILEGFEEEVNM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHHCCC
SADTQATISGGTLRIRIAEGKGIDIEVPLNGNVGAGKSIAVPAVKAEKGTVTAAPVAVEA
CCCCEEEECCCEEEEEEECCCCEEEEEECCCCCCCCCEEECCEEECCCCCEEECCEEECC
KKEVKLEEKIVRSVTRKHYKIDKVELAKETKIEGTTLYIRENICEDAFNVDQLVKDIKLE
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEEHHHHHHHCCHHHHHHHCEEE
IITPDKYNTYSETIMDVQPIATKEGSDAKLGEGVTRVIDGAIVMVTGIDEDGVQVGEFGS
EECCCCCCCHHHHHHCCCCCCCCCCCCCCHHCCHHHHHCCEEEEEECCCCCCCEECCCCC
SEGILEENIMWGRPGAPDKGEIFIKTQVTIKRGTGMERPGPLAAHKATDFITQEIREALK
CCCCCCCCCEECCCCCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
DVEDDSLVVNTETFEQVRRPGKKKVVVVKEIMGQGAMHDNLILPLEPVGVIGAKPNVDLG
CCCCCCEEEEHHHHHHHHCCCCCEEEEEHHHHCCCCCCCCEEEECCCCEEECCCCCCCCC
NVPVMLAPTEVLDGGIHALTCIGPASKECSRHYFREPLVMECMQDEEVDLAGVIFVGSPQ
CCCEEEECHHHHCCCCEEEEEECCCHHHHHHHHHCCCHHHHHCCCCCCCEEEEEEECCCC
INSEKFYVSERLGMMVEAMDVDGAFVTTEGFGNNHIDFASHVEQIGMRGVPCVAFSFCAV
CCCCEEEHHHHHCCEEEEEECCCEEEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHH
QGALVVGNKHMKYMVDNNKSEGGIENEVLSCNTLCKEDAVRGLAMIKAAMSGEEVKKPER
CCEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHH
AWNANVKENNIEMIEKSTGNKIDRVLNETSIPMSEKRKEKYTTK
HHCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10085076 [H]