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The map label for this gene is cymR [H]

Identifier: 153935743

GI number: 153935743

Start: 1261828

End: 1262265

Strand: Direct

Name: cymR [H]

Synonym: CLC_1221

Alternate gene names: 153935743

Gene position: 1261828-1262265 (Clockwise)

Preceding gene: 153935247

Following gene: 153936282

Centisome position: 33.55

GC content: 27.85

Gene sequence:

>438_bases
ATGAAAATATCAACTAAAGGAAAATATGGCATAAAGGCTATAATAGACTTAGCCATAAATTCTACAGAAGAAGCAGTTAC
TTTAAAAAGTATTTCTGAAAGACAAAACATATCCGAGGGATATTTAGAACAAATATTTTCTTTATTAAGAAAGAATAATT
TAATAAAGGGAATAAAAGGAGCTCAAGGCGGCTATATATTAGAAAAGGATTCAGCACATATAACTGCAGGTGAAATACTA
AGAGCTTTGGAAGGAGATCTATCCGTAGTAGAACTTAATGATGATTATTTAAATAATAGAATGGAAAAATCTATTAAGAC
AAATTTATGGGATAGAATTAATGAAAGCATAGAAAGAGTAGTAGATTCTATAACTTTAGAAGATTTAGTAGAGGCATACA
AAAAATCAGATAACCAAAACATAATGTACTACATATAA

Upstream 100 bases:

>100_bases
AATATAAAAGTGAAAAATTTTTTAAAAAATATTGACATAAATTAATTAAGAGAATATAATCATAGTAAATAGATAGGAAT
ACTATGAAAGAGGAGATTTT

Downstream 100 bases:

>100_bases
TGTTGTAGTACAGTTTATTTAAAATGAATACCTAGTAAACAAATAAGAATAATCAGGTATTGCTTAATAAAATATAGAGT
AGAATTAATGCTATAGTAGA

Product: rrf2 family protein

Products: NA

Alternate protein names: Cysteine metabolism repressor [H]

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MKISTKGKYGIKAIIDLAINSTEEAVTLKSISERQNISEGYLEQIFSLLRKNNLIKGIKGAQGGYILEKDSAHITAGEIL
RALEGDLSVVELNDDYLNNRMEKSIKTNLWDRINESIERVVDSITLEDLVEAYKKSDNQNIMYYI

Sequences:

>Translated_145_residues
MKISTKGKYGIKAIIDLAINSTEEAVTLKSISERQNISEGYLEQIFSLLRKNNLIKGIKGAQGGYILEKDSAHITAGEIL
RALEGDLSVVELNDDYLNNRMEKSIKTNLWDRINESIERVVDSITLEDLVEAYKKSDNQNIMYYI
>Mature_145_residues
MKISTKGKYGIKAIIDLAINSTEEAVTLKSISERQNISEGYLEQIFSLLRKNNLIKGIKGAQGGYILEKDSAHITAGEIL
RALEGDLSVVELNDDYLNNRMEKSIKTNLWDRINESIERVVDSITLEDLVEAYKKSDNQNIMYYI

Specific function: Master repressor of cysteine metabolism in B.subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK), sulfonates (ssu), or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulate

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=130, Percent_Identity=36.9230769230769, Blast_Score=99, Evalue=1e-22,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000944 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 16415; Mature: 16415

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISTKGKYGIKAIIDLAINSTEEAVTLKSISERQNISEGYLEQIFSLLRKNNLIKGIKG
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCC
AQGGYILEKDSAHITAGEILRALEGDLSVVELNDDYLNNRMEKSIKTNLWDRINESIERV
CCCCEEEECCCCCCCHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDSITLEDLVEAYKKSDNQNIMYYI
HHHCCHHHHHHHHHCCCCCEEEEEC
>Mature Secondary Structure
MKISTKGKYGIKAIIDLAINSTEEAVTLKSISERQNISEGYLEQIFSLLRKNNLIKGIKG
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCC
AQGGYILEKDSAHITAGEILRALEGDLSVVELNDDYLNNRMEKSIKTNLWDRINESIERV
CCCCEEEECCCCCCCHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDSITLEDLVEAYKKSDNQNIMYYI
HHHCCHHHHHHHHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]