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The map label for this gene is cobB [H]

Identifier: 153935703

GI number: 153935703

Start: 1003670

End: 1004992

Strand: Direct

Name: cobB [H]

Synonym: CLC_0979

Alternate gene names: 153935703

Gene position: 1003670-1004992 (Clockwise)

Preceding gene: 153936619

Following gene: 153934794

Centisome position: 26.69

GC content: 27.29

Gene sequence:

>1323_bases
ATGAGAAGTATAATAATATCTTCCAATAGTAGTGGTGGAGGAAAAACTACAGTAACTTTAGGGCTTATGAAGGCTTTAAT
TAAAAAAGATTATAAAGTTCAAGGCTATAAAGTTGGTCCTGATTATATAGATCCTGCCTTTCATTCTTATGTAACAGAAA
ATAGTTCTAGAAATTTAGATTTGTTTTTAATGGGAGAGGATGGTGTTAAAGCATCCTATAGTAGAGGCAAAGGTGATTTA
GGAGTAATAGAAGGGGTAATGGGATTGTATGATGGAAAAGGGATAGATACAAAATATTCTACAGCACATCTATCAAAGGT
TTTAAATTTACCAGTGGTTTTAGTATTAACTCCAAAGGCTCAAAGTGCTACCTTATGTGCAGAAATTATGGGAATATTAA
ATTATGAAAAGATAAATATAGTTGGAGTAATCTTTAATAAAGTAAGTGAAAGCTATTATAAATTGCTTAAGAAATTAGTT
GAAGAAAATTGTGGATTAAAGGTCTTTGGATATGTACCAAAGGAAGAAAAATTAGAATTGAAAAGTAGACATTTAGGTCT
TATACAAAGTAGTGAAATAAAAGATTTAGAAGAAAAAATAGATATATGTAGTGAATTAATTTTAAAATATGTAGATATAG
AAAATTTAATAAATCACTTTGAAAAAACAGAAAAATATAAAGATAATTTTTACTTAGAAAACAAAAATCTAAATATAGGC
ATACCTTATGATAAAGCTTTTAGTTTTTATTATAAAGAGAATATAGAACTATTAGAAAATGTAGGTAACATAAAATATTT
TAGTCCTATGAAGGATGAAAAATTGCCAGAGTATTTAGATTTTTTATATATAGGTGGGGGATACCCAGAGGTTTTTATAA
AGGAATTAAGAGAAAACAAATCCATGCTAAGTAGCATAAATAAAGAATTAAATAATGGACTCACATGCTATGCGGAATGT
GGAGGACTTATGTATTTAACAGAAGGCATAGAAGATTTAGAGGGATATTATAAAGAAGCAGTAGGATTTTTAAACGGTCA
ATGTCATATGACTAAAAGACTTCAAAACTTTGGGTATGCTGAAATAGAAGTGGAAAAGGAAAATAAAATATTATCTAAAG
GGTTAAAAATTAATTGTCATGAATTTCATAAATCCTATGTGGATTTAAAAGAGGATAAAATATATGAACTTACTAAAAAT
CTCTATGATGATTCTACAAAAAAATGGAGTTGTGGATATATAAAAAATAATACGTTGGCAGCATATGCTCATGTACATTT
CTTCGGAAATATGGATTTTGTAAGAAATTTATTTAATAGATAA

Upstream 100 bases:

>100_bases
AAAGTTGAGGGTAGAATTTTTTCATTTTATGAAAAAATTCCACTCTGTACTCTGTACTCTGTACTATGTACTCTGTACTC
TGTATCAAAGGGGTGTTTTT

Downstream 100 bases:

>100_bases
AAAGAAAATTAGAGAGGTAAGGGTATGAAAGATTATATAAAAAAACCAATGGATATAGAAAAAAGAAGTTTTGAAATAAT
AGAAGAAGAGATGGGTAAGC

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MRSIIISSNSSGGGKTTVTLGLMKALIKKDYKVQGYKVGPDYIDPAFHSYVTENSSRNLDLFLMGEDGVKASYSRGKGDL
GVIEGVMGLYDGKGIDTKYSTAHLSKVLNLPVVLVLTPKAQSATLCAEIMGILNYEKINIVGVIFNKVSESYYKLLKKLV
EENCGLKVFGYVPKEEKLELKSRHLGLIQSSEIKDLEEKIDICSELILKYVDIENLINHFEKTEKYKDNFYLENKNLNIG
IPYDKAFSFYYKENIELLENVGNIKYFSPMKDEKLPEYLDFLYIGGGYPEVFIKELRENKSMLSSINKELNNGLTCYAEC
GGLMYLTEGIEDLEGYYKEAVGFLNGQCHMTKRLQNFGYAEIEVEKENKILSKGLKINCHEFHKSYVDLKEDKIYELTKN
LYDDSTKKWSCGYIKNNTLAAYAHVHFFGNMDFVRNLFNR

Sequences:

>Translated_440_residues
MRSIIISSNSSGGGKTTVTLGLMKALIKKDYKVQGYKVGPDYIDPAFHSYVTENSSRNLDLFLMGEDGVKASYSRGKGDL
GVIEGVMGLYDGKGIDTKYSTAHLSKVLNLPVVLVLTPKAQSATLCAEIMGILNYEKINIVGVIFNKVSESYYKLLKKLV
EENCGLKVFGYVPKEEKLELKSRHLGLIQSSEIKDLEEKIDICSELILKYVDIENLINHFEKTEKYKDNFYLENKNLNIG
IPYDKAFSFYYKENIELLENVGNIKYFSPMKDEKLPEYLDFLYIGGGYPEVFIKELRENKSMLSSINKELNNGLTCYAEC
GGLMYLTEGIEDLEGYYKEAVGFLNGQCHMTKRLQNFGYAEIEVEKENKILSKGLKINCHEFHKSYVDLKEDKIYELTKN
LYDDSTKKWSCGYIKNNTLAAYAHVHFFGNMDFVRNLFNR
>Mature_440_residues
MRSIIISSNSSGGGKTTVTLGLMKALIKKDYKVQGYKVGPDYIDPAFHSYVTENSSRNLDLFLMGEDGVKASYSRGKGDL
GVIEGVMGLYDGKGIDTKYSTAHLSKVLNLPVVLVLTPKAQSATLCAEIMGILNYEKINIVGVIFNKVSESYYKLLKKLV
EENCGLKVFGYVPKEEKLELKSRHLGLIQSSEIKDLEEKIDICSELILKYVDIENLINHFEKTEKYKDNFYLENKNLNIG
IPYDKAFSFYYKENIELLENVGNIKYFSPMKDEKLPEYLDFLYIGGGYPEVFIKELRENKSMLSSINKELNNGLTCYAEC
GGLMYLTEGIEDLEGYYKEAVGFLNGQCHMTKRLQNFGYAEIEVEKENKILSKGLKINCHEFHKSYVDLKEDKIYELTKN
LYDDSTKKWSCGYIKNNTLAAYAHVHFFGNMDFVRNLFNR

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 50208; Mature: 50208

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSIIISSNSSGGGKTTVTLGLMKALIKKDYKVQGYKVGPDYIDPAFHSYVTENSSRNLD
CCEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHCCCCCCCEE
LFLMGEDGVKASYSRGKGDLGVIEGVMGLYDGKGIDTKYSTAHLSKVLNLPVVLVLTPKA
EEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEECCCC
QSATLCAEIMGILNYEKINIVGVIFNKVSESYYKLLKKLVEENCGLKVFGYVPKEEKLEL
CHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHH
KSRHLGLIQSSEIKDLEEKIDICSELILKYVDIENLINHFEKTEKYKDNFYLENKNLNIG
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCEEEECCCEEEE
IPYDKAFSFYYKENIELLENVGNIKYFSPMKDEKLPEYLDFLYIGGGYPEVFIKELRENK
CCHHHHHHHHHHCCHHHHHCCCCCEEECCCCCCCCHHHHCEEEECCCCHHHHHHHHHHHH
SMLSSINKELNNGLTCYAECGGLMYLTEGIEDLEGYYKEAVGFLNGQCHMTKRLQNFGYA
HHHHHHHHHHHCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCE
EIEVEKENKILSKGLKINCHEFHKSYVDLKEDKIYELTKNLYDDSTKKWSCGYIKNNTLA
EEEEECHHHHHHCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEECCEEECCCEE
AYAHVHFFGNMDFVRNLFNR
EEEEEEEECCHHHHHHHHCC
>Mature Secondary Structure
MRSIIISSNSSGGGKTTVTLGLMKALIKKDYKVQGYKVGPDYIDPAFHSYVTENSSRNLD
CCEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHCCCCCCCEE
LFLMGEDGVKASYSRGKGDLGVIEGVMGLYDGKGIDTKYSTAHLSKVLNLPVVLVLTPKA
EEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEECCCC
QSATLCAEIMGILNYEKINIVGVIFNKVSESYYKLLKKLVEENCGLKVFGYVPKEEKLEL
CHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHH
KSRHLGLIQSSEIKDLEEKIDICSELILKYVDIENLINHFEKTEKYKDNFYLENKNLNIG
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCEEEECCCEEEE
IPYDKAFSFYYKENIELLENVGNIKYFSPMKDEKLPEYLDFLYIGGGYPEVFIKELRENK
CCHHHHHHHHHHCCHHHHHCCCCCEEECCCCCCCCHHHHCEEEECCCCHHHHHHHHHHHH
SMLSSINKELNNGLTCYAECGGLMYLTEGIEDLEGYYKEAVGFLNGQCHMTKRLQNFGYA
HHHHHHHHHHHCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCE
EIEVEKENKILSKGLKINCHEFHKSYVDLKEDKIYELTKNLYDDSTKKWSCGYIKNNTLA
EEEEECHHHHHHCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEECCEEECCCEE
AYAHVHFFGNMDFVRNLFNR
EEEEEEEECCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]