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The map label for this gene is 153935690

Identifier: 153935690

GI number: 153935690

Start: 2375219

End: 2376760

Strand: Reverse

Name: 153935690

Synonym: CLC_2250

Alternate gene names: NA

Gene position: 2376760-2375219 (Counterclockwise)

Preceding gene: 153937504

Following gene: 153934717

Centisome position: 63.2

GC content: 34.05

Gene sequence:

>1542_bases
ATGGGTCCAACGAAATATATAATAATCGCAGTGGTTATTATAATAATTTGTGTAATTTTAGGCTTATATATAGTTGATAA
AAAAGCTAAAGAAAAATTATCAGAGGCATCCAAAGAAGCTAGAAGATTAAAAGAAGAGGCTGAAAGAGATGCAGAGGCAA
AAAAGAAAGAAGCTATATTAGAGGCTAAAGAAGAAGCTCATAAATTAAGAGCAGAGGTTGAAAGAGAAAATAGAGAAAGA
CGTAATGAAGTTCAGCGTCTTGAAAGAAGAATAATTCAAAAAGAAGAAGCTTTAGATAAAAAGAGTGAGGCCCTTGAAAA
CAAAGAAGAAGCTTTAAACAAAAAGCAACAAAAAATAGAAGATGTGGAAACACATATGGAGGAGCTTCACGAAAAGCAAA
GAACAGAATTAGAGAGAATTTCAGGACTTACAACAGAACAGGCTAAAGAATTTTTATTAGAACAGGTTAGAAAAGAAGTA
AAACATGAAACTGCAGTAATGATAAAAGAAATAGAAACTAAAGCTAAGGAAGAAGCAGACAAAAGAGCAAGAGAAGTCAT
TACATATGCCATCCAAAGATGTGCTGCAGATCATGTAGCAGAAACTACAGTACATGTAGTTAATCTTCCTAACGATGAAA
TGAAAGGAAGAATAATTGGAAGAGAAGGAAGAAATATAAGAACATTAGAAACGCTTACAGGGGTTGATCTAATAATAGAT
GATACACCAGAAGCAGTTATATTATCTGGTTTCGATCCAATTAGAAGAGAAGTTGCAAGAATTGCATTAGAAAAATTAAT
AGTTGATGGAAGAATCCATCCAGCTAGAATTGAAGAAATGGTTGAGAAAGCTAAGAAAGAAGTTGAAATTAGTATTAAAG
AAGAAGGAGAACAGGCTACCTTTGAAACAGGTATTCATGGTCTTCATATTGAATTGATTAGATTATTAGGTAGATTAAAG
TACAGAACAAGTTATGGTCAAAATGTATTAAAGCATTCTATAGAAGTTTCACATTTAGCAGGTCTTATGGCCTCCGAACT
TGGAATAGACCCAACTTTAGCAAAAAGAGTAGGTTTATTACATGATATAGGTAAGGCAGTAGACCATGAAGTTGAGGGAC
CACACGCAATTATAGGATCTGAGATAGCTAAAAAATACCGTGAATCCGCATTAGTAGTAAATGCTATAGGAGCTCATCAT
GGTGATATGGAACCACAATCTCTAGAAGCAATACTTGTTCAAGCGGCAGATGCTATATCTGCAGCAAGACCAGGAGCTAG
AAGAGAAACTTTAGAAGCTTATATAAAGAGATTAGAAAAGTTAGAAGAAATTGCAAATGAGTGTGAAGGTGTAGAAAAGT
CATATGCAATTCAAGCGGGAAGAGAAATAAGAATTATGGTTAAACCAGAGGTGCTTGATGATACTGGCTGCATTGAAATG
GCTAGGAATATAGTTAAACAGATAGAAAGTGAACTTGAATATCCTGGTCAAATAAAGGTTAATGTCATCAGAGAAACCCG
TGCCATTGAATATGCTAAATAA

Upstream 100 bases:

>100_bases
TCTGGTTTAGCATACATGATCCAATTGAATAATATGACACCTTTTCTAAGCTTCATATTTACTTATATATGGCAAGCAGA
AAAAGCAAAGGAGGTGTTTT

Downstream 100 bases:

>100_bases
TTAGATTATAAAATAAATTCCTTTTAAGTTTTATAAGTTGCTAAAATTTACAAAATTTAAAAGGAATTTTTAATTTTTTG
TAGAATAGATATATGTAAGT

Product: phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 513; Mature: 512

Protein sequence:

>513_residues
MGPTKYIIIAVVIIIICVILGLYIVDKKAKEKLSEASKEARRLKEEAERDAEAKKKEAILEAKEEAHKLRAEVERENRER
RNEVQRLERRIIQKEEALDKKSEALENKEEALNKKQQKIEDVETHMEELHEKQRTELERISGLTTEQAKEFLLEQVRKEV
KHETAVMIKEIETKAKEEADKRAREVITYAIQRCAADHVAETTVHVVNLPNDEMKGRIIGREGRNIRTLETLTGVDLIID
DTPEAVILSGFDPIRREVARIALEKLIVDGRIHPARIEEMVEKAKKEVEISIKEEGEQATFETGIHGLHIELIRLLGRLK
YRTSYGQNVLKHSIEVSHLAGLMASELGIDPTLAKRVGLLHDIGKAVDHEVEGPHAIIGSEIAKKYRESALVVNAIGAHH
GDMEPQSLEAILVQAADAISAARPGARRETLEAYIKRLEKLEEIANECEGVEKSYAIQAGREIRIMVKPEVLDDTGCIEM
ARNIVKQIESELEYPGQIKVNVIRETRAIEYAK

Sequences:

>Translated_513_residues
MGPTKYIIIAVVIIIICVILGLYIVDKKAKEKLSEASKEARRLKEEAERDAEAKKKEAILEAKEEAHKLRAEVERENRER
RNEVQRLERRIIQKEEALDKKSEALENKEEALNKKQQKIEDVETHMEELHEKQRTELERISGLTTEQAKEFLLEQVRKEV
KHETAVMIKEIETKAKEEADKRAREVITYAIQRCAADHVAETTVHVVNLPNDEMKGRIIGREGRNIRTLETLTGVDLIID
DTPEAVILSGFDPIRREVARIALEKLIVDGRIHPARIEEMVEKAKKEVEISIKEEGEQATFETGIHGLHIELIRLLGRLK
YRTSYGQNVLKHSIEVSHLAGLMASELGIDPTLAKRVGLLHDIGKAVDHEVEGPHAIIGSEIAKKYRESALVVNAIGAHH
GDMEPQSLEAILVQAADAISAARPGARRETLEAYIKRLEKLEEIANECEGVEKSYAIQAGREIRIMVKPEVLDDTGCIEM
ARNIVKQIESELEYPGQIKVNVIRETRAIEYAK
>Mature_512_residues
GPTKYIIIAVVIIIICVILGLYIVDKKAKEKLSEASKEARRLKEEAERDAEAKKKEAILEAKEEAHKLRAEVERENRERR
NEVQRLERRIIQKEEALDKKSEALENKEEALNKKQQKIEDVETHMEELHEKQRTELERISGLTTEQAKEFLLEQVRKEVK
HETAVMIKEIETKAKEEADKRAREVITYAIQRCAADHVAETTVHVVNLPNDEMKGRIIGREGRNIRTLETLTGVDLIIDD
TPEAVILSGFDPIRREVARIALEKLIVDGRIHPARIEEMVEKAKKEVEISIKEEGEQATFETGIHGLHIELIRLLGRLKY
RTSYGQNVLKHSIEVSHLAGLMASELGIDPTLAKRVGLLHDIGKAVDHEVEGPHAIIGSEIAKKYRESALVVNAIGAHHG
DMEPQSLEAILVQAADAISAARPGARRETLEAYIKRLEKLEEIANECEGVEKSYAIQAGREIRIMVKPEVLDDTGCIEMA
RNIVKQIESELEYPGQIKVNVIRETRAIEYAK

Specific function: Catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'- terminal of RNA

COG id: COG1418

COG function: function code R; Predicted HD superfamily hydrolase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CNPD_CLOB1 (A7FVX8)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001384578.1
- ProteinModelPortal:   A7FVX8
- SMR:   A7FVX8
- STRING:   A7FVX8
- GeneID:   5396696
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_2267
- eggNOG:   COG1418
- HOGENOM:   HBG734610
- OMA:   HPGRIEE
- ProtClustDB:   PRK12704
- BioCyc:   CBOT441770:CLB_2267-MONOMER
- HAMAP:   MF_00335
- InterPro:   IPR017705
- InterPro:   IPR022711
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR003607
- InterPro:   IPR006675
- SMART:   SM00471
- SMART:   SM00322
- TIGRFAMs:   TIGR00277
- TIGRFAMs:   TIGR03319

Pfam domain/function: PF12072 DUF3552; PF00013 KH_1

EC number: =3.1.4.16

Molecular weight: Translated: 58114; Mature: 57982

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1aa22948)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPTKYIIIAVVIIIICVILGLYIVDKKAKEKLSEASKEARRLKEEAERDAEAKKKEAIL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAKEEAHKLRAEVERENRERRNEVQRLERRIIQKEEALDKKSEALENKEEALNKKQQKIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVETHMEELHEKQRTELERISGLTTEQAKEFLLEQVRKEVKHETAVMIKEIETKAKEEAD
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRAREVITYAIQRCAADHVAETTVHVVNLPNDEMKGRIIGREGRNIRTLETLTGVDLIID
HHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHCCCEECCCCCCCCHHHHHCCCEEEEC
DTPEAVILSGFDPIRREVARIALEKLIVDGRIHPARIEEMVEKAKKEVEISIKEEGEQAT
CCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEECCCCCHHH
FETGIHGLHIELIRLLGRLKYRTSYGQNVLKHSIEVSHLAGLMASELGIDPTLAKRVGLL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
HDIGKAVDHEVEGPHAIIGSEIAKKYRESALVVNAIGAHHGDMEPQSLEAILVQAADAIS
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
AARPGARRETLEAYIKRLEKLEEIANECEGVEKSYAIQAGREIRIMVKPEVLDDTGCIEM
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCCCCCCCHHHH
ARNIVKQIESELEYPGQIKVNVIRETRAIEYAK
HHHHHHHHHHHCCCCCCEEEEEEHHHHHHCCCH
>Mature Secondary Structure 
GPTKYIIIAVVIIIICVILGLYIVDKKAKEKLSEASKEARRLKEEAERDAEAKKKEAIL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAKEEAHKLRAEVERENRERRNEVQRLERRIIQKEEALDKKSEALENKEEALNKKQQKIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVETHMEELHEKQRTELERISGLTTEQAKEFLLEQVRKEVKHETAVMIKEIETKAKEEAD
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRAREVITYAIQRCAADHVAETTVHVVNLPNDEMKGRIIGREGRNIRTLETLTGVDLIID
HHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHCCCEECCCCCCCCHHHHHCCCEEEEC
DTPEAVILSGFDPIRREVARIALEKLIVDGRIHPARIEEMVEKAKKEVEISIKEEGEQAT
CCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEECCCCCHHH
FETGIHGLHIELIRLLGRLKYRTSYGQNVLKHSIEVSHLAGLMASELGIDPTLAKRVGLL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
HDIGKAVDHEVEGPHAIIGSEIAKKYRESALVVNAIGAHHGDMEPQSLEAILVQAADAIS
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
AARPGARRETLEAYIKRLEKLEEIANECEGVEKSYAIQAGREIRIMVKPEVLDDTGCIEM
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCCCCCCCHHHH
ARNIVKQIESELEYPGQIKVNVIRETRAIEYAK
HHHHHHHHHHHCCCCCCEEEEEEHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA