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The map label for this gene is secA

Identifier: 153935608

GI number: 153935608

Start: 200058

End: 202565

Strand: Direct

Name: secA

Synonym: CLC_0227

Alternate gene names: 153935608

Gene position: 200058-202565 (Clockwise)

Preceding gene: 153936354

Following gene: 153936079

Centisome position: 5.32

GC content: 31.06

Gene sequence:

>2508_bases
ATGGGAATTTTAAATAAAATATTTGGTACATATAGTGAAAGAGAACTTAGAAGAGTTAACCCTATAGTAAACAAAATAGA
AGCTTTAGATGAAAAAATGCAATCCTTAAAAGATGAAGATTTTAAGCTAAAAACTGAAGAATTTAAAAGTAGATTAGAAA
AAGGGGAAAAACTAGATGATATTTTACCAGAAGCTTTTGCCTTAGTTAGAGAAGCGGCACATAGAACCATAGGACTTAAA
CATTATAGAGAACAATTAATAGGCGGTGTAGTATTACACCAAGGAAGAATTGGAGAAATGAAAACCGGTGAAGGTAAAAC
TTTAGTTGCTACATTGCCAGCCTATGTAAATGCATTAACAGGAAAAGGGGTACATATAGTTACAGTTAATGATTACTTGG
CAAAAAGAGATAGGGATTTAATGGCTCCGGTATATGAATTTTTAGGGCTAAAAGTAGGAGTTATTTTGCATAATTTAAAT
AATGAAGAAAGACAAGAAGCTTATGGTTCAGATATAACTTATGGAACAAATAGTGAATTTGGCTTTGATTATTTAAGAGA
TAATATGGTAGTTTATAAAGAAGAAAGAGTTCAAAGAAAGTTAAACTTTTCAATTGTGGATGAAGTGGACTCTATATTAA
TAGATGAAGCTAGAACTCCATTAATAATATCAGGTCAAGGGGAGAAGTCTACAGAGTTTTATAAGGTTGCAGATTATTTC
ACTAAATCTCTAATAGCTGAAAAAGATTTTACAATAGATGAAAAAGCTAATTCAGCTATGCTTACAGATGAAGGTGTTAA
TAAAGCAGAGAATTTCTTTAAAGTAGATAACTATGCTGATGCAGAAAACATGGAAATACAACACCATGTAGTTCAAGCTT
TAAAAGCTAACTATGTAATGAAAAAAGATAAAGATTATATGATTAAGGATGGAGAAATTCTAATAGTTGATGAGTTTACA
GGAAGAGCTATGGAAGGAAGAAGATATAGCGATGGATTGCACCAAGCTATAGAAGCTAAAGAAGGCGTTAGAGTAGAAAG
AGAATCTAAAACCTTAGCTACAATAACTTATCAAAACTATTTTAGAATGTACAATAAATTGTCTGGTATGACAGGAACTG
CTCAAACAGAAGAAAATGAATTTAGAGAAATCTATGGATTAGATGTAATTGTAATACCTACACATGAGCCTATAGCAAGA
ATAGATAATGCTGATGTAGTATATAAATCAGAAAAGGGTAAATTTAAAGCCATAGTTGATGAAATAGTAGAAAGATATAA
AAAAGGTCAACCAATGCTAGTAGGTACGGTAAGCATAGAAAAATCAGAAATGTTATCCTCTATGTTAAAGAAAAAAGGAG
TACCTCATCAAGTATTAAATGCTAAATATCATGAAAAAGAAGCGGAAATAATATCTCATGCAGGGGAATATGGGATGGTT
ACAATAGCCACTAATATGGCAGGCCGTGGTACAGATATAAAGCTTACTAAGGAAGCTGAAGAAGCAGGCGGGCTTATGAT
TATAGGTACAGAAAGACATGAGTCTAGAAGAATAGACAACCAATTAAGAGGACGTTCTGGTCGTCAAGGAGATCCTGGTG
AATCAAGATTTTTTGTATCTTTAGAAGATGATTTAATGAGAATATTTGGTTCAGAAAGAATACAAGGAATAGTTGATAAA
TTAGGACTGGCTGAAGATGAAGCTATAGAAAGTAAAATGGTAAGTTCAGCTATAGAAAGTGCTCAAAAGAAGGTAGAAGG
AAATAACTTTGATATAAGAAAAACTTTATTACAATATGATGATGTAATAAATAAACAAAGAGAAATAATCTATAAACAAA
GAAGTGAGGTTTTAGAGGGAGAAGACTTAAAGGATCAAATAAGAGATATGATAAGGGATGTGGTTTATACTGCAGTAAAT
TCTCATATTTCAGGAGTAGAAGAAGAGTTTCAAACAGAACTTCAAAATCTTGTTAATTATTTAGAAGACATATGCTTACC
AAAGGCCTTAGTAAAGGTAAAAGATATAAGTAATTTATCAGATGAAGAAATAAAAGAAAAATTATTAGAAGCAGTAGAGA
ATATATATATCCGCAAAGAAAAAGAAATTGGGGAAGAACAAATAAGAGAAATAGAAAGAGTAATATTACTTAGGGTTGTA
GATACTAAATGGATGGATCATATAGATGATATGGATCACTTAAAACAAGGTATAGGACTAAGAGCATATAGACAACAAGA
TCCAGTTCAAGCGTATCAATTTGAAGGTAGTGAAATGTTTGAGGAAATGATCTATAACATTAAAGTAGATACAGTAAGAT
ATTTATTCCATGTAGAAGTAGAAAAAGCACCTGAAAGAGAGAAAGTTGCAAAAGAAACATCAACTAATTATGATGAAGAT
TCAGTAAAAAAACAACCTATAAAAAAGGAAAATAGAATAGGTAGAAATGATATGTGTCCTTGCGGAAGTGGGAAAAAATA
TAAAAATTGTTGTGGTAGAATGGCATAA

Upstream 100 bases:

>100_bases
ACATAATTATTATTCTAAAAAGTTGAATGGAATATAGTTAAATGATATAATTTATAAAGTTAAGACCTATAAAATTTGAT
AAATAGTGAGGATGAATAAT

Downstream 100 bases:

>100_bases
AAATATATTATAATAAAACCGGAAACTTTATTTGGTTTCTGGTTTTATAACCTTTAAGGTACATTCAAATAAATAACAAG
TCAGTATGACAGTCTATTTT

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 835; Mature: 834

Protein sequence:

>835_residues
MGILNKIFGTYSERELRRVNPIVNKIEALDEKMQSLKDEDFKLKTEEFKSRLEKGEKLDDILPEAFALVREAAHRTIGLK
HYREQLIGGVVLHQGRIGEMKTGEGKTLVATLPAYVNALTGKGVHIVTVNDYLAKRDRDLMAPVYEFLGLKVGVILHNLN
NEERQEAYGSDITYGTNSEFGFDYLRDNMVVYKEERVQRKLNFSIVDEVDSILIDEARTPLIISGQGEKSTEFYKVADYF
TKSLIAEKDFTIDEKANSAMLTDEGVNKAENFFKVDNYADAENMEIQHHVVQALKANYVMKKDKDYMIKDGEILIVDEFT
GRAMEGRRYSDGLHQAIEAKEGVRVERESKTLATITYQNYFRMYNKLSGMTGTAQTEENEFREIYGLDVIVIPTHEPIAR
IDNADVVYKSEKGKFKAIVDEIVERYKKGQPMLVGTVSIEKSEMLSSMLKKKGVPHQVLNAKYHEKEAEIISHAGEYGMV
TIATNMAGRGTDIKLTKEAEEAGGLMIIGTERHESRRIDNQLRGRSGRQGDPGESRFFVSLEDDLMRIFGSERIQGIVDK
LGLAEDEAIESKMVSSAIESAQKKVEGNNFDIRKTLLQYDDVINKQREIIYKQRSEVLEGEDLKDQIRDMIRDVVYTAVN
SHISGVEEEFQTELQNLVNYLEDICLPKALVKVKDISNLSDEEIKEKLLEAVENIYIRKEKEIGEEQIREIERVILLRVV
DTKWMDHIDDMDHLKQGIGLRAYRQQDPVQAYQFEGSEMFEEMIYNIKVDTVRYLFHVEVEKAPEREKVAKETSTNYDED
SVKKQPIKKENRIGRNDMCPCGSGKKYKNCCGRMA

Sequences:

>Translated_835_residues
MGILNKIFGTYSERELRRVNPIVNKIEALDEKMQSLKDEDFKLKTEEFKSRLEKGEKLDDILPEAFALVREAAHRTIGLK
HYREQLIGGVVLHQGRIGEMKTGEGKTLVATLPAYVNALTGKGVHIVTVNDYLAKRDRDLMAPVYEFLGLKVGVILHNLN
NEERQEAYGSDITYGTNSEFGFDYLRDNMVVYKEERVQRKLNFSIVDEVDSILIDEARTPLIISGQGEKSTEFYKVADYF
TKSLIAEKDFTIDEKANSAMLTDEGVNKAENFFKVDNYADAENMEIQHHVVQALKANYVMKKDKDYMIKDGEILIVDEFT
GRAMEGRRYSDGLHQAIEAKEGVRVERESKTLATITYQNYFRMYNKLSGMTGTAQTEENEFREIYGLDVIVIPTHEPIAR
IDNADVVYKSEKGKFKAIVDEIVERYKKGQPMLVGTVSIEKSEMLSSMLKKKGVPHQVLNAKYHEKEAEIISHAGEYGMV
TIATNMAGRGTDIKLTKEAEEAGGLMIIGTERHESRRIDNQLRGRSGRQGDPGESRFFVSLEDDLMRIFGSERIQGIVDK
LGLAEDEAIESKMVSSAIESAQKKVEGNNFDIRKTLLQYDDVINKQREIIYKQRSEVLEGEDLKDQIRDMIRDVVYTAVN
SHISGVEEEFQTELQNLVNYLEDICLPKALVKVKDISNLSDEEIKEKLLEAVENIYIRKEKEIGEEQIREIERVILLRVV
DTKWMDHIDDMDHLKQGIGLRAYRQQDPVQAYQFEGSEMFEEMIYNIKVDTVRYLFHVEVEKAPEREKVAKETSTNYDED
SVKKQPIKKENRIGRNDMCPCGSGKKYKNCCGRMA
>Mature_834_residues
GILNKIFGTYSERELRRVNPIVNKIEALDEKMQSLKDEDFKLKTEEFKSRLEKGEKLDDILPEAFALVREAAHRTIGLKH
YREQLIGGVVLHQGRIGEMKTGEGKTLVATLPAYVNALTGKGVHIVTVNDYLAKRDRDLMAPVYEFLGLKVGVILHNLNN
EERQEAYGSDITYGTNSEFGFDYLRDNMVVYKEERVQRKLNFSIVDEVDSILIDEARTPLIISGQGEKSTEFYKVADYFT
KSLIAEKDFTIDEKANSAMLTDEGVNKAENFFKVDNYADAENMEIQHHVVQALKANYVMKKDKDYMIKDGEILIVDEFTG
RAMEGRRYSDGLHQAIEAKEGVRVERESKTLATITYQNYFRMYNKLSGMTGTAQTEENEFREIYGLDVIVIPTHEPIARI
DNADVVYKSEKGKFKAIVDEIVERYKKGQPMLVGTVSIEKSEMLSSMLKKKGVPHQVLNAKYHEKEAEIISHAGEYGMVT
IATNMAGRGTDIKLTKEAEEAGGLMIIGTERHESRRIDNQLRGRSGRQGDPGESRFFVSLEDDLMRIFGSERIQGIVDKL
GLAEDEAIESKMVSSAIESAQKKVEGNNFDIRKTLLQYDDVINKQREIIYKQRSEVLEGEDLKDQIRDMIRDVVYTAVNS
HISGVEEEFQTELQNLVNYLEDICLPKALVKVKDISNLSDEEIKEKLLEAVENIYIRKEKEIGEEQIREIERVILLRVVD
TKWMDHIDDMDHLKQGIGLRAYRQQDPVQAYQFEGSEMFEEMIYNIKVDTVRYLFHVEVEKAPEREKVAKETSTNYDEDS
VKKQPIKKENRIGRNDMCPCGSGKKYKNCCGRMA

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family

Homologues:

Organism=Escherichia coli, GI1786287, Length=897, Percent_Identity=49.0523968784838, Blast_Score=847, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECA_CLOB1 (A7FQJ3)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001382577.1
- ProteinModelPortal:   A7FQJ3
- SMR:   A7FQJ3
- STRING:   A7FQJ3
- GeneID:   5397389
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_0213
- eggNOG:   COG0653
- HOGENOM:   HBG284200
- OMA:   GGMVLHD
- ProtClustDB:   PRK12904
- BioCyc:   CBOT441770:CLB_0213-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01382
- InterPro:   IPR004027
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116
- Gene3D:   G3DSA:1.10.3060.10
- PRINTS:   PR00906
- SMART:   SM00957
- SMART:   SM00958
- TIGRFAMs:   TIGR00963

Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW; SSF81767 SecA_PP_bd; SSF81886 SecA_SW

EC number: NA

Molecular weight: Translated: 95609; Mature: 95478

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS01312 SECA; PS51196 SECA_MOTOR_DEAD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGILNKIFGTYSERELRRVNPIVNKIEALDEKMQSLKDEDFKLKTEEFKSRLEKGEKLDD
CCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHCCCHHHH
ILPEAFALVREAAHRTIGLKHYREQLIGGVVLHQGRIGEMKTGEGKTLVATLPAYVNALT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCEEEEEHHHHHHHHC
GKGVHIVTVNDYLAKRDRDLMAPVYEFLGLKVGVILHNLNNEERQEAYGSDITYGTNSEF
CCCEEEEEECHHHHHCCCHHHHHHHHHHHHHHHHHEECCCCHHHHHHCCCCCCCCCCCCC
GFDYLRDNMVVYKEERVQRKLNFSIVDEVDSILIDEARTPLIISGQGEKSTEFYKVADYF
CHHHHHCCEEEEHHHHHHHHHCHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHH
TKSLIAEKDFTIDEKANSAMLTDEGVNKAENFFKVDNYADAENMEIQHHVVQALKANYVM
HHHHHHCCCCCCCCCCCCCEECCCCCCHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHE
KKDKDYMIKDGEILIVDEFTGRAMEGRRYSDGLHQAIEAKEGVRVERESKTLATITYQNY
ECCCCCEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCEEEEEHHHHH
FRMYNKLSGMTGTAQTEENEFREIYGLDVIVIPTHEPIARIDNADVVYKSEKGKFKAIVD
HHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEECCCCHHHHCCCCCEEEECCCCHHHHHHH
EIVERYKKGQPMLVGTVSIEKSEMLSSMLKKKGVPHQVLNAKYHEKEAEIISHAGEYGMV
HHHHHHHCCCCEEEEEEECCHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHCCCCCCEE
TIATNMAGRGTDIKLTKEAEEAGGLMIIGTERHESRRIDNQLRGRSGRQGDPGESRFFVS
EEEECCCCCCCCEEEECCHHHHCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEEE
LEDDLMRIFGSERIQGIVDKLGLAEDEAIESKMVSSAIESAQKKVEGNNFDIRKTLLQYD
EHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
DVINKQREIIYKQRSEVLEGEDLKDQIRDMIRDVVYTAVNSHISGVEEEFQTELQNLVNY
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LEDICLPKALVKVKDISNLSDEEIKEKLLEAVENIYIRKEKEIGEEQIREIERVILLRVV
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHH
DTKWMDHIDDMDHLKQGIGLRAYRQQDPVQAYQFEGSEMFEEMIYNIKVDTVRYLFHVEV
HHHHHHHHCCHHHHHHCCCCCHHCCCCCCHHHHCCCHHHHHHHHHHCCHHHEEEEEEEEH
EKAPEREKVAKETSTNYDEDSVKKQPIKKENRIGRNDMCPCGSGKKYKNCCGRMA
HCCCCHHHHHHHHCCCCCHHHHHHCCCCHHHCCCCCCCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure 
GILNKIFGTYSERELRRVNPIVNKIEALDEKMQSLKDEDFKLKTEEFKSRLEKGEKLDD
CCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHCCCHHHH
ILPEAFALVREAAHRTIGLKHYREQLIGGVVLHQGRIGEMKTGEGKTLVATLPAYVNALT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCEEEEEHHHHHHHHC
GKGVHIVTVNDYLAKRDRDLMAPVYEFLGLKVGVILHNLNNEERQEAYGSDITYGTNSEF
CCCEEEEEECHHHHHCCCHHHHHHHHHHHHHHHHHEECCCCHHHHHHCCCCCCCCCCCCC
GFDYLRDNMVVYKEERVQRKLNFSIVDEVDSILIDEARTPLIISGQGEKSTEFYKVADYF
CHHHHHCCEEEEHHHHHHHHHCHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHH
TKSLIAEKDFTIDEKANSAMLTDEGVNKAENFFKVDNYADAENMEIQHHVVQALKANYVM
HHHHHHCCCCCCCCCCCCCEECCCCCCHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHE
KKDKDYMIKDGEILIVDEFTGRAMEGRRYSDGLHQAIEAKEGVRVERESKTLATITYQNY
ECCCCCEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCEEEEEHHHHH
FRMYNKLSGMTGTAQTEENEFREIYGLDVIVIPTHEPIARIDNADVVYKSEKGKFKAIVD
HHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEECCCCHHHHCCCCCEEEECCCCHHHHHHH
EIVERYKKGQPMLVGTVSIEKSEMLSSMLKKKGVPHQVLNAKYHEKEAEIISHAGEYGMV
HHHHHHHCCCCEEEEEEECCHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHCCCCCCEE
TIATNMAGRGTDIKLTKEAEEAGGLMIIGTERHESRRIDNQLRGRSGRQGDPGESRFFVS
EEEECCCCCCCCEEEECCHHHHCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEEE
LEDDLMRIFGSERIQGIVDKLGLAEDEAIESKMVSSAIESAQKKVEGNNFDIRKTLLQYD
EHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
DVINKQREIIYKQRSEVLEGEDLKDQIRDMIRDVVYTAVNSHISGVEEEFQTELQNLVNY
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LEDICLPKALVKVKDISNLSDEEIKEKLLEAVENIYIRKEKEIGEEQIREIERVILLRVV
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHH
DTKWMDHIDDMDHLKQGIGLRAYRQQDPVQAYQFEGSEMFEEMIYNIKVDTVRYLFHVEV
HHHHHHHHCCHHHHHHCCCCCHHCCCCCCHHHHCCCHHHHHHHHHHCCHHHEEEEEEEEH
EKAPEREKVAKETSTNYDEDSVKKQPIKKENRIGRNDMCPCGSGKKYKNCCGRMA
HCCCCHHHHHHHHCCCCCHHHHHHCCCCHHHCCCCCCCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA