Click here to switch to the map view.

The map label for this gene is thiJ [C]

Identifier: 153935560

GI number: 153935560

Start: 2776490

End: 2777041

Strand: Direct

Name: thiJ [C]

Synonym: CLC_2643

Alternate gene names: 153935560

Gene position: 2776490-2777041 (Clockwise)

Preceding gene: 153936758

Following gene: 153935770

Centisome position: 73.83

GC content: 31.34

Gene sequence:

>552_bases
ATGACAAAAGTTTTAGTATTTATAGCAGAGGGCTTTGAAGAAATTGAAGCTCTAACTGTAGTAGATGTATTAAGAAGAGC
CAATATTCGATGCGATATGTGCAGTATTACTTCTAATAAAGAAGTAAAGGGTGCTCATAATATTTTAGTTAATGTAGATA
AAACTTTAGAAGAAATCAAAACTAATGACTATAGTTCTTTAGTTATTCCTGGGGGCATGCCTGGTGCCGCTAACTTAAGA
GATAATAATAAAGTAATAAATTTAGTAAAGGAATTTAATAGGGATGAAAAATTAATAGCTGCCATATGTGCAGGTCCAAT
AGTCTTAAGCAAGGCAAATATAATAAAAGGAAAAGAGGTTACTTCCTATCCTGGTTTTGAAGAGGATTTAAAAGAAGGTA
TTTATAAAGAAGATTTAGTTGTGCAAGATGGAAACATAATAACCAGTAGGGGACCTTCTGCGGCAATGTATTTTGCCTTT
AAAATACTAGAAAATTTAAAAAAAGATTCTGCAAAAGGAATAAAAGAAGACATGCTTTTGCACCTTCTTTAA

Upstream 100 bases:

>100_bases
ATAAATAAATTTTTTATATTCAAAAAAAATTAATATTATTCTTTTAATAAATTGTATAAAATTATTATATTAACTTAATA
AGATTAAAGGAGGAACATTT

Downstream 100 bases:

>100_bases
AGAAATTTATCCGATGACTACCCGCTCTAATACCCCCATCGCACTCTGTGAAAGCGATTCGCACCAAATCGAAGATTTGG
ACTCTCTGCTTTTCTTCAAA

Product: DJ-1 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MTKVLVFIAEGFEEIEALTVVDVLRRANIRCDMCSITSNKEVKGAHNILVNVDKTLEEIKTNDYSSLVIPGGMPGAANLR
DNNKVINLVKEFNRDEKLIAAICAGPIVLSKANIIKGKEVTSYPGFEEDLKEGIYKEDLVVQDGNIITSRGPSAAMYFAF
KILENLKKDSAKGIKEDMLLHLL

Sequences:

>Translated_183_residues
MTKVLVFIAEGFEEIEALTVVDVLRRANIRCDMCSITSNKEVKGAHNILVNVDKTLEEIKTNDYSSLVIPGGMPGAANLR
DNNKVINLVKEFNRDEKLIAAICAGPIVLSKANIIKGKEVTSYPGFEEDLKEGIYKEDLVVQDGNIITSRGPSAAMYFAF
KILENLKKDSAKGIKEDMLLHLL
>Mature_182_residues
TKVLVFIAEGFEEIEALTVVDVLRRANIRCDMCSITSNKEVKGAHNILVNVDKTLEEIKTNDYSSLVIPGGMPGAANLRD
NNKVINLVKEFNRDEKLIAAICAGPIVLSKANIIKGKEVTSYPGFEEDLKEGIYKEDLVVQDGNIITSRGPSAAMYFAFK
ILENLKKDSAKGIKEDMLLHLL

Specific function: Thiamine biosynthesis [C]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=183, Percent_Identity=36.6120218579235, Blast_Score=110, Evalue=7e-25,
Organism=Homo sapiens, GI31543380, Length=183, Percent_Identity=36.6120218579235, Blast_Score=110, Evalue=7e-25,
Organism=Escherichia coli, GI87081736, Length=167, Percent_Identity=32.9341317365269, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI87082219, Length=154, Percent_Identity=29.2207792207792, Blast_Score=75, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17531319, Length=184, Percent_Identity=39.1304347826087, Blast_Score=114, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17558714, Length=168, Percent_Identity=33.9285714285714, Blast_Score=83, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28571932, Length=169, Percent_Identity=38.4615384615385, Blast_Score=116, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24653499, Length=180, Percent_Identity=40.5555555555556, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 20199; Mature: 20068

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVLVFIAEGFEEIEALTVVDVLRRANIRCDMCSITSNKEVKGAHNILVNVDKTLEEIK
CCEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEECHHHHHHHH
TNDYSSLVIPGGMPGAANLRDNNKVINLVKEFNRDEKLIAAICAGPIVLSKANIIKGKEV
CCCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCEECCCCC
TSYPGFEEDLKEGIYKEDLVVQDGNIITSRGPSAAMYFAFKILENLKKDSAKGIKEDMLL
CCCCCCHHHHHCCCCCCCEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
HLL
HCC
>Mature Secondary Structure 
TKVLVFIAEGFEEIEALTVVDVLRRANIRCDMCSITSNKEVKGAHNILVNVDKTLEEIK
CEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEECHHHHHHHH
TNDYSSLVIPGGMPGAANLRDNNKVINLVKEFNRDEKLIAAICAGPIVLSKANIIKGKEV
CCCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCEECCCCC
TSYPGFEEDLKEGIYKEDLVVQDGNIITSRGPSAAMYFAFKILENLKKDSAKGIKEDMLL
CCCCCCHHHHHCCCCCCCEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
HLL
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]