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The map label for this gene is fhuB [H]

Identifier: 153935164

GI number: 153935164

Start: 357497

End: 358525

Strand: Direct

Name: fhuB [H]

Synonym: CLC_0369

Alternate gene names: 153935164

Gene position: 357497-358525 (Clockwise)

Preceding gene: 153936756

Following gene: 153934542

Centisome position: 9.51

GC content: 36.64

Gene sequence:

>1029_bases
ATGCAAAAGACCTATAATAAAAAGCGACAATTAGGAGCTTTGAATTTTACAATCTATATGATTGTAGGAGTGGTTTTGCT
AGTAATTATGTCAGCGGCGTCAATTTCTTTTGGTGCTGCTGATATGAATTTGACTACAGCTTGGGGAGCCATTTTTAATT
TTGACTCTTCTTTAACTGAACATCAGATTATTCAAACTCTCAGACTTCCTCGTATAGCAGCTAATATAATTGTTGGATCA
AGCCTTGCGATATGCGGTGCTATAATGCAGGGAACTACAAGAAATCCTCTTGCTGATTCTGGACTTATGGGTATAAGTAG
CGGTGCTACTTTTGCTATGGCTTTTTGTATGGCATTTTTACCTGGTGGAAGTTACGGACAGATGATGCTTTTTGCCTGCA
TTGGTGCAGCTATTACTACAGGTATGACTTATTTTATTGCATCTATTGGTAGAGGAGGCATGAAACCACAGAGACTTGTT
TTAGCAGGTATTTCTATATCAATGCTATTTGGCGCTTTTAGCCAATATCTTTCTATTAAATATAAACTCGGACATGCATT
AGCTTATTGGACTGCTGGAGGAACGGCAGGTGCTAAATGGAGTGAACTTGCTATAGTTTTCCCATTCTTTATTGTAGGTA
TTATTGTAGCTTTTGTTATATCGCCTTCAATTACGGTTTTAAATCTTGGAGATGATGCAGCTATAGGTCTTGGAATTAAT
ACTAAGAAGGTTAAAGGGGTATCTACTGTAGTAGTTTTAATACTTACAGGGATTTCTGTAATTGTTGTTGGACCTGTTGG
CTTTGTAGGATTAATAGTACCTCATATTGTCCGCTACCTTATAGGGGTAGATTATAGATACATTATTCCAGCTTCAGGAT
TATATGGAGCCTTGATTACTGTGACAGCAGATTTAGTTGGAAGGCTTATTAATAAGCCCTATGAAACTCCAATTGGAATT
ATTTTTGCTTTAATAGGTGTTCCGTATTTTCTTTATCTTACAAGGATACAAAGGAGGGAATTTGAATGA

Upstream 100 bases:

>100_bases
ATTATTCTGATATTACAAGTCTTACTGAACAACTTGACTATATGAGTGATGCAATAAATTCATTAGTTAAATAATTCTAA
TATAAGAAAGGAAAATAAAT

Downstream 100 bases:

>100_bases
AGAAAAAGGGTTATTCAGTTTCACGTGGTCTAACTATTATTTTGCTACTTACCATTATTTTGTTAGTTGTGGCAGTAATA
AGTGTAAACTCAGGTAAAAT

Product: iron compound ABC transporter, permease protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein B; Ferrichrome transport system permease protein fhuB; Iron(III)-hydroxamate import system permease protein fhuB [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MQKTYNKKRQLGALNFTIYMIVGVVLLVIMSAASISFGAADMNLTTAWGAIFNFDSSLTEHQIIQTLRLPRIAANIIVGS
SLAICGAIMQGTTRNPLADSGLMGISSGATFAMAFCMAFLPGGSYGQMMLFACIGAAITTGMTYFIASIGRGGMKPQRLV
LAGISISMLFGAFSQYLSIKYKLGHALAYWTAGGTAGAKWSELAIVFPFFIVGIIVAFVISPSITVLNLGDDAAIGLGIN
TKKVKGVSTVVVLILTGISVIVVGPVGFVGLIVPHIVRYLIGVDYRYIIPASGLYGALITVTADLVGRLINKPYETPIGI
IFALIGVPYFLYLTRIQRREFE

Sequences:

>Translated_342_residues
MQKTYNKKRQLGALNFTIYMIVGVVLLVIMSAASISFGAADMNLTTAWGAIFNFDSSLTEHQIIQTLRLPRIAANIIVGS
SLAICGAIMQGTTRNPLADSGLMGISSGATFAMAFCMAFLPGGSYGQMMLFACIGAAITTGMTYFIASIGRGGMKPQRLV
LAGISISMLFGAFSQYLSIKYKLGHALAYWTAGGTAGAKWSELAIVFPFFIVGIIVAFVISPSITVLNLGDDAAIGLGIN
TKKVKGVSTVVVLILTGISVIVVGPVGFVGLIVPHIVRYLIGVDYRYIIPASGLYGALITVTADLVGRLINKPYETPIGI
IFALIGVPYFLYLTRIQRREFE
>Mature_342_residues
MQKTYNKKRQLGALNFTIYMIVGVVLLVIMSAASISFGAADMNLTTAWGAIFNFDSSLTEHQIIQTLRLPRIAANIIVGS
SLAICGAIMQGTTRNPLADSGLMGISSGATFAMAFCMAFLPGGSYGQMMLFACIGAAITTGMTYFIASIGRGGMKPQRLV
LAGISISMLFGAFSQYLSIKYKLGHALAYWTAGGTAGAKWSELAIVFPFFIVGIIVAFVISPSITVLNLGDDAAIGLGIN
TKKVKGVSTVVVLILTGISVIVVGPVGFVGLIVPHIVRYLIGVDYRYIIPASGLYGALITVTADLVGRLINKPYETPIGI
IFALIGVPYFLYLTRIQRREFE

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790741, Length=287, Percent_Identity=34.8432055749129, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1786347, Length=326, Percent_Identity=30.9815950920245, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI1790740, Length=318, Percent_Identity=28.9308176100629, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1786805, Length=290, Percent_Identity=32.4137931034483, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1788004, Length=277, Percent_Identity=33.2129963898917, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786804, Length=288, Percent_Identity=28.8194444444444, Blast_Score=112, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36408; Mature: 36408

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKTYNKKRQLGALNFTIYMIVGVVLLVIMSAASISFGAADMNLTTAWGAIFNFDSSLTE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHH
HQIIQTLRLPRIAANIIVGSSLAICGAIMQGTTRNPLADSGLMGISSGATFAMAFCMAFL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHC
PGGSYGQMMLFACIGAAITTGMTYFIASIGRGGMKPQRLVLAGISISMLFGAFSQYLSIK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHH
YKLGHALAYWTAGGTAGAKWSELAIVFPFFIVGIIVAFVISPSITVLNLGDDAAIGLGIN
HHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEECCCC
TKKVKGVSTVVVLILTGISVIVVGPVGFVGLIVPHIVRYLIGVDYRYIIPASGLYGALIT
CHHHCHHHHHHHHHHHCCHHEEECHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHH
VTADLVGRLINKPYETPIGIIFALIGVPYFLYLTRIQRREFE
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQKTYNKKRQLGALNFTIYMIVGVVLLVIMSAASISFGAADMNLTTAWGAIFNFDSSLTE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHH
HQIIQTLRLPRIAANIIVGSSLAICGAIMQGTTRNPLADSGLMGISSGATFAMAFCMAFL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHC
PGGSYGQMMLFACIGAAITTGMTYFIASIGRGGMKPQRLVLAGISISMLFGAFSQYLSIK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHH
YKLGHALAYWTAGGTAGAKWSELAIVFPFFIVGIIVAFVISPSITVLNLGDDAAIGLGIN
HHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEECCCC
TKKVKGVSTVVVLILTGISVIVVGPVGFVGLIVPHIVRYLIGVDYRYIIPASGLYGALIT
CHHHCHHHHHHHHHHHCCHHEEECHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHH
VTADLVGRLINKPYETPIGIIFALIGVPYFLYLTRIQRREFE
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377; 8388528 [H]