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The map label for this gene is grdA [H]

Identifier: 153935110

GI number: 153935110

Start: 1345500

End: 1345976

Strand: Direct

Name: grdA [H]

Synonym: CLC_1300

Alternate gene names: 153935110

Gene position: 1345500-1345976 (Clockwise)

Preceding gene: 153936746

Following gene: 153937685

Centisome position: 35.78

GC content: 36.48

Gene sequence:

>477_bases
ATGAGTCTATTTGAAGGGAAAAAAGTAATAATAATTGGAGATAGAGATGGAATACCAGGTCCAGCTATAGAAAAATGCAT
AGAAGGTACAGGCGCTGAAGTAGTTTTTTCATCCACAGAATGCTTTGTTTGAACTGCCGCCGGAGCAATGGATTTGGAAA
ATCAAAAAAGAGTAAAAACATTAACAGAAAAACATGGTGCTGAAAATATATTAGTAATTTTAGGTGCAGCAGAGGGAGAA
GCAGCAGGTCTTGCTGCGGAGACAGTTACTAATGGAGATCCAACTTTTGCAGGTCCATTGTCCAATGTCCAGTTAGGACT
AAGGGTTTATCATGCGGTAGAACCAGAATTTAAAGAAGAAGTGAATGAAGAAGTTTATGAGGAAGAAATAGGTATGATGG
AAATGGTTTTAGAGGTAGATGAAATTATAGAAGAGATGACAGATATAAGAACAGAGTTTTGTAAATTCCTTGATTAA

Upstream 100 bases:

>100_bases
AAACACACACTATAAAATTTTAAAGATTATTTAGTCATTTAAAGTGTGTATATAAATATCAAGGAATTTAAAATATAAAT
AAATTAAGGGAGGAATTTTA

Downstream 100 bases:

>100_bases
AACAGGGAAAGTAGATAAATAAAGAATTATAAAATTTAAGAGGCTGTACTATAGGTTTATAATCCAGCCTCCTAAATATT
AGGGGGGAAAAGCTATGAAT

Product: glycine/sarcosine/betaine reductase complex protein A

Products: NA

Alternate protein names: Selenoprotein PA; Thioredoxin reductase complex selenoprotein A [H]

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MSLFEGKKVIIIGDRDGIPGPAIEKCIEGTGAEVVFSSTECFVUTAAGAMDLENQKRVKTLTEKHGAENILVILGAAEGE
AAGLAAETVTNGDPTFAGPLSNVQLGLRVYHAVEPEFKEEVNEEVYEEEIGMMEMVLEVDEIIEEMTDIRTEFCKFLD

Sequences:

>Translated_158_residues
MSLFEGKKVIIIGDRDGIPGPAIEKCIEGTGAEVVFSSTECFV*TAAGAMDLENQKRVKTLTEKHGAENILVILGAAEGE
AAGLAAETVTNGDPTFAGPLSNVQLGLRVYHAVEPEFKEEVNEEVYEEEIGMMEMVLEVDEIIEEMTDIRTEFCKFLD
>Mature_157_residues
SLFEGKKVIIIGDRDGIPGPAIEKCIEGTGAEVVFSSTECFV*TAAGAMDLENQKRVKTLTEKHGAENILVILGAAEGEA
AGLAAETVTNGDPTFAGPLSNVQLGLRVYHAVEPEFKEEVNEEVYEEEIGMMEMVLEVDEIIEEMTDIRTEFCKFLD

Specific function: In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a c

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the grdA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006812 [H]

Pfam domain/function: PF04723 GRDA [H]

EC number: =1.21.4.2; =1.21.4.3; =1.21.4.4 [H]

Molecular weight: Translated: 17054; Mature: 16922

Theoretical pI: Translated: 3.94; Mature: 3.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFEGKKVIIIGDRDGIPGPAIEKCIEGTGAEVVFSSTECFVTAAGAMDLENQKRVKTL
CCCCCCCEEEEEECCCCCCCHHHHHHHCCCCCEEEEECCCEEEEECCCCCCCCHHHHHHH
TEKHGAENILVILGAAEGEAAGLAAETVTNGDPTFAGPLSNVQLGLRVYHAVEPEFKEEV
HHHCCCCEEEEEEECCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHH
NEEVYEEEIGMMEMVLEVDEIIEEMTDIRTEFCKFLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLFEGKKVIIIGDRDGIPGPAIEKCIEGTGAEVVFSSTECFVTAAGAMDLENQKRVKTL
CCCCCCEEEEEECCCCCCCHHHHHHHCCCCCEEEEECCCEEEEECCCCCCCCHHHHHHH
TEKHGAENILVILGAAEGEAAGLAAETVTNGDPTFAGPLSNVQLGLRVYHAVEPEFKEEV
HHHCCCCEEEEEEECCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHH
NEEVYEEEIGMMEMVLEVDEIIEEMTDIRTEFCKFLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA