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The map label for this gene is murA-1 [H]

Identifier: 153935043

GI number: 153935043

Start: 185809

End: 187065

Strand: Direct

Name: murA-1 [H]

Synonym: CLC_0207

Alternate gene names: 153935043

Gene position: 185809-187065 (Clockwise)

Preceding gene: 153935794

Following gene: 153937283

Centisome position: 4.94

GC content: 33.02

Gene sequence:

>1257_bases
ATGGATAAGATAGTGGTTAATGGTGGAAGTCAATTAAAAGGTGATGTAAACATAAGTACAGCTAAAAATTCAGTATTACC
AATCATTGCAGGTAGTATATTGAGTGGAAATAAATGCGTTATAGATAATGCACCAATGCTAGAGGATGTATTTGTTATTG
GAGAAATTTTAAAAAGTATTTCAGCCAAAGTTAATATAGATGAGGTTAATAACAGAGTTATAATAGATTCTAAACCAGTG
GATAATTTAGAACCTGATAGTGATTTAGTTAAAAAAATGAGAGCATCATTTTTGCTAATGGGACCTATGATGTCTAGGTT
TGGAAGGTTTAAGATATCATTACCAGGAGGATGTAATATAGGTACAAGACCCATAGATTTACATTTAAAAGGATTCACTG
CCCTTGGAGCAAAAGTTAACATAGGGCATGGTTATGTAGAAGCTGTAGCAGATAAATTAATAGGAAATAAAATTTATTTA
GATTTTCCTTCTGTAGGGGCTACGGAAAATATAATGATGGCATCAGTTATGGCAGAAGGAGAGACCGTTATAGAAAATGC
AGCAGAAGAACCAGAAATAGAGGATTTAGGAAGGTTTTTAAACAGCATAGGAGCAAATATTATAGGAGCAGGGACAGATA
CAGTAAGAATAATAGGAGTTAATGAATTAAAGGGAACAACACATAGACCTATATATGATAGAATAGAAGCAGGAACTTTT
ATGATAGCTGCTGCTATAACTAAGAGTAGAATAAAAATAAATGGTGTTATAGAAGAACATTTAAAACCTATAATCGCAAA
GCTTACAGAGATGGGCGTTGATATAAAAATAAAAGGAGAAACTGCTATAGTAGATGGGAGAAAAATATTAAATCCAGTAG
ATATAAAAACTATGCCCTATCCAGGTTTCCCAACGGATATGCAGGCGCAAATGATGGCTTTATTGGCCACTATAAAAGGA
ACCAGCATTATCACAGAAACTATATTTGAAAATAGATTTATGCATGTATCTGAAATGAAGAGAATGGGTGCAGATGTAAA
AATAGATGGAAGAAGTGCCGTAATAGAAGGTGTAAATAAATTAACAGGGACAGAAGTTAAAGCTACAGATCTAAGGGCAG
GAGCGGCTCTTATATTATGTGCTCTAGCAGCTGAAGGAAAAACAGAAATAACAGATGTATATCATATAGATAGAGGATAT
GTAAAAATAGAGGAAAAGTTAAATAAATTAGGAGCAAATATTAGACGAGTACATTAA

Upstream 100 bases:

>100_bases
ATTATGCTGTATGTAAATATAATTCAGAAAAAACTTACTTAATATTGGGAACGCCACAGATAAACCTAACATATTAGTAA
TATCGAAATGGAGGATAATA

Downstream 100 bases:

>100_bases
AATTTAATAATTGTGTATGATAAATAACTCATGGTGATTATTCGCTATGAGTTTTTATTATATATATATAAACTTTTGAG
TTTATATATTAAGCTTATTT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2 [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MDKIVVNGGSQLKGDVNISTAKNSVLPIIAGSILSGNKCVIDNAPMLEDVFVIGEILKSISAKVNIDEVNNRVIIDSKPV
DNLEPDSDLVKKMRASFLLMGPMMSRFGRFKISLPGGCNIGTRPIDLHLKGFTALGAKVNIGHGYVEAVADKLIGNKIYL
DFPSVGATENIMMASVMAEGETVIENAAEEPEIEDLGRFLNSIGANIIGAGTDTVRIIGVNELKGTTHRPIYDRIEAGTF
MIAAAITKSRIKINGVIEEHLKPIIAKLTEMGVDIKIKGETAIVDGRKILNPVDIKTMPYPGFPTDMQAQMMALLATIKG
TSIITETIFENRFMHVSEMKRMGADVKIDGRSAVIEGVNKLTGTEVKATDLRAGAALILCALAAEGKTEITDVYHIDRGY
VKIEEKLNKLGANIRRVH

Sequences:

>Translated_418_residues
MDKIVVNGGSQLKGDVNISTAKNSVLPIIAGSILSGNKCVIDNAPMLEDVFVIGEILKSISAKVNIDEVNNRVIIDSKPV
DNLEPDSDLVKKMRASFLLMGPMMSRFGRFKISLPGGCNIGTRPIDLHLKGFTALGAKVNIGHGYVEAVADKLIGNKIYL
DFPSVGATENIMMASVMAEGETVIENAAEEPEIEDLGRFLNSIGANIIGAGTDTVRIIGVNELKGTTHRPIYDRIEAGTF
MIAAAITKSRIKINGVIEEHLKPIIAKLTEMGVDIKIKGETAIVDGRKILNPVDIKTMPYPGFPTDMQAQMMALLATIKG
TSIITETIFENRFMHVSEMKRMGADVKIDGRSAVIEGVNKLTGTEVKATDLRAGAALILCALAAEGKTEITDVYHIDRGY
VKIEEKLNKLGANIRRVH
>Mature_418_residues
MDKIVVNGGSQLKGDVNISTAKNSVLPIIAGSILSGNKCVIDNAPMLEDVFVIGEILKSISAKVNIDEVNNRVIIDSKPV
DNLEPDSDLVKKMRASFLLMGPMMSRFGRFKISLPGGCNIGTRPIDLHLKGFTALGAKVNIGHGYVEAVADKLIGNKIYL
DFPSVGATENIMMASVMAEGETVIENAAEEPEIEDLGRFLNSIGANIIGAGTDTVRIIGVNELKGTTHRPIYDRIEAGTF
MIAAAITKSRIKINGVIEEHLKPIIAKLTEMGVDIKIKGETAIVDGRKILNPVDIKTMPYPGFPTDMQAQMMALLATIKG
TSIITETIFENRFMHVSEMKRMGADVKIDGRSAVIEGVNKLTGTEVKATDLRAGAALILCALAAEGKTEITDVYHIDRGY
VKIEEKLNKLGANIRRVH

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=419, Percent_Identity=47.7326968973747, Blast_Score=375, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45135; Mature: 45135

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIVVNGGSQLKGDVNISTAKNSVLPIIAGSILSGNKCVIDNAPMLEDVFVIGEILKSI
CCEEEECCCCCEECCEEEECCCCCEEEEEECCEECCCEEEECCCCHHHHHHHHHHHHHHH
SAKVNIDEVNNRVIIDSKPVDNLEPDSDLVKKMRASFLLMGPMMSRFGRFKISLPGGCNI
CCEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCC
GTRPIDLHLKGFTALGAKVNIGHGYVEAVADKLIGNKIYLDFPSVGATENIMMASVMAEG
CCCEEEEEEECEEEECCEEECCCHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCC
ETVIENAAEEPEIEDLGRFLNSIGANIIGAGTDTVRIIGVNELKGTTHRPIYDRIEAGTF
HHHHHCCCCCCCHHHHHHHHHHHCCCEEECCCCEEEEEEEHHCCCCCCCCHHHHHCCCCE
MIAAAITKSRIKINGVIEEHLKPIIAKLTEMGVDIKIKGETAIVDGRKILNPVDIKTMPY
EEEEEHHHCEEEEECHHHHHHHHHHHHHHHCCCEEEECCCEEEECCHHHCCCCCCEECCC
PGFPTDMQAQMMALLATIKGTSIITETIFENRFMHVSEMKRMGADVKIDGRSAVIEGVNK
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHCCCCEEECCCHHHHHHHHH
LTGTEVKATDLRAGAALILCALAAEGKTEITDVYHIDRGYVKIEEKLNKLGANIRRVH
HCCCCEEEHHHHCCHHHHHHHHHCCCCCCEEEEEEECCCEEEHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDKIVVNGGSQLKGDVNISTAKNSVLPIIAGSILSGNKCVIDNAPMLEDVFVIGEILKSI
CCEEEECCCCCEECCEEEECCCCCEEEEEECCEECCCEEEECCCCHHHHHHHHHHHHHHH
SAKVNIDEVNNRVIIDSKPVDNLEPDSDLVKKMRASFLLMGPMMSRFGRFKISLPGGCNI
CCEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCC
GTRPIDLHLKGFTALGAKVNIGHGYVEAVADKLIGNKIYLDFPSVGATENIMMASVMAEG
CCCEEEEEEECEEEECCEEECCCHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCC
ETVIENAAEEPEIEDLGRFLNSIGANIIGAGTDTVRIIGVNELKGTTHRPIYDRIEAGTF
HHHHHCCCCCCCHHHHHHHHHHHCCCEEECCCCEEEEEEEHHCCCCCCCCHHHHHCCCCE
MIAAAITKSRIKINGVIEEHLKPIIAKLTEMGVDIKIKGETAIVDGRKILNPVDIKTMPY
EEEEEHHHCEEEEECHHHHHHHHHHHHHHHCCCEEEECCCEEEECCHHHCCCCCCEECCC
PGFPTDMQAQMMALLATIKGTSIITETIFENRFMHVSEMKRMGADVKIDGRSAVIEGVNK
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHCCCCEEECCCHHHHHHHHH
LTGTEVKATDLRAGAALILCALAAEGKTEITDVYHIDRGYVKIEEKLNKLGANIRRVH
HCCCCEEEHHHHCCHHHHHHHHHCCCCCCEEEEEEECCCEEEHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]