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The map label for this gene is cobK [H]

Identifier: 153935010

GI number: 153935010

Start: 1024244

End: 1025011

Strand: Direct

Name: cobK [H]

Synonym: CLC_1006

Alternate gene names: 153935010

Gene position: 1024244-1025011 (Clockwise)

Preceding gene: 153934736

Following gene: 153936266

Centisome position: 27.24

GC content: 25.78

Gene sequence:

>768_bases
ATGATAGCTTTAATATTAGGTACTTCAGAAGGAAGAGAGATACTTTCTCTACTAAATAAGTTTACAGATAATATATTAAT
ATCTACAGCAACAGCTTATGGCGGAGAAATTTTAAAGGATTATAAATATAAAAAATTAAATACCAAACCTTTAAATAAAG
AACAGCTTTTAAATATGCTAAAAGAAAATCAAGTAAATATATTAATTGATGCTTCTCATCCCTATGCTTTAGAAGTAACT
AAAAATGCTAGAGAAGTATCAAAAGATTTAAATATAGAATATGTAAGATATGAAAGACCATCCTCAGCAGAGGAATTTAA
GGAAAATAAAAAAGTAGTATTTTTAGAGGATTATAAAGATTTAAATGAGGCTTTAAAAAATATAAAAGGTAATATATTAA
ATACTTCTGGTAGTAGAAATATGGATAAAATTTTAGATTTAAAACTAGAAAATAGAATTATCCATAGAGTGCTTCCATCT
GTAAAAGTTTTAGAAGATTGCTTTAATTTAGGGGTAAAAGTAGAGGATCTTATGGCTATAAAGGGACCTATAAGTAAAGA
GTTAAATAAAGCCTTTATAAAGGATTATGATGCCAAGGCATTAATATTAAAAGATAGTGGACCACAAGGTGGTACAGAGG
AAAAAATATTAGCCTGTCTAGAGTGTGATATATATGCTTTGGTAATAAAAAGAAAGAAAATAAATTATGAAAGAGAATTT
AATAATATAGAGATTTTAGTTGAATACATAAGTTCAATGATCAATTAA

Upstream 100 bases:

>100_bases
GGAAATAGGATTATATTTATCTTATTATAATGGAAATATTGAGAATCAAGTAATTTTGGCTAGCTTATAGTAACAATATA
TAAGATGCAGGAGAGATAAA

Downstream 100 bases:

>100_bases
CAATGATTAAGTATTAATATTGTTTAACTTGAAAATAATTTAATAGATTAAAAACTTAATATTGGGGGAAGAAAACAAGA
TGAAAACTAAAAGATTAGTT

Product: cobalt-precorrin-6x reductase

Products: Precorrin 6A; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MIALILGTSEGREILSLLNKFTDNILISTATAYGGEILKDYKYKKLNTKPLNKEQLLNMLKENQVNILIDASHPYALEVT
KNAREVSKDLNIEYVRYERPSSAEEFKENKKVVFLEDYKDLNEALKNIKGNILNTSGSRNMDKILDLKLENRIIHRVLPS
VKVLEDCFNLGVKVEDLMAIKGPISKELNKAFIKDYDAKALILKDSGPQGGTEEKILACLECDIYALVIKRKKINYEREF
NNIEILVEYISSMIN

Sequences:

>Translated_255_residues
MIALILGTSEGREILSLLNKFTDNILISTATAYGGEILKDYKYKKLNTKPLNKEQLLNMLKENQVNILIDASHPYALEVT
KNAREVSKDLNIEYVRYERPSSAEEFKENKKVVFLEDYKDLNEALKNIKGNILNTSGSRNMDKILDLKLENRIIHRVLPS
VKVLEDCFNLGVKVEDLMAIKGPISKELNKAFIKDYDAKALILKDSGPQGGTEEKILACLECDIYALVIKRKKINYEREF
NNIEILVEYISSMIN
>Mature_255_residues
MIALILGTSEGREILSLLNKFTDNILISTATAYGGEILKDYKYKKLNTKPLNKEQLLNMLKENQVNILIDASHPYALEVT
KNAREVSKDLNIEYVRYERPSSAEEFKENKKVVFLEDYKDLNEALKNIKGNILNTSGSRNMDKILDLKLENRIIHRVLPS
VKVLEDCFNLGVKVEDLMAIKGPISKELNKAFIKDYDAKALILKDSGPQGGTEEKILACLECDIYALVIKRKKINYEREF
NNIEILVEYISSMIN

Specific function: Catalyzes the reduction of the macrocycle of cobalt- precorrin-6X into cobalt-precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: 1.3.1.54

Molecular weight: Translated: 29119; Mature: 29119

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALILGTSEGREILSLLNKFTDNILISTATAYGGEILKDYKYKKLNTKPLNKEQLLNML
CEEEEEECCCCHHHHHHHHHHHCCEEEEEHHHHCHHHHHHHHHCCCCCCCCCHHHHHHHH
KENQVNILIDASHPYALEVTKNAREVSKDLNIEYVRYERPSSAEEFKENKKVVFLEDYKD
HCCCEEEEEECCCCEEEEECCCHHHHHHCCCEEEEEECCCCCHHHHHHCCCEEEEHHHHH
LNEALKNIKGNILNTSGSRNMDKILDLKLENRIIHRVLPSVKVLEDCFNLGVKVEDLMAI
HHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHH
KGPISKELNKAFIKDYDAKALILKDSGPQGGTEEKILACLECDIYALVIKRKKINYEREF
CCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHCCHHEEEHHHHHCCHHHHC
NNIEILVEYISSMIN
CHHHHHHHHHHHHCC
>Mature Secondary Structure
MIALILGTSEGREILSLLNKFTDNILISTATAYGGEILKDYKYKKLNTKPLNKEQLLNML
CEEEEEECCCCHHHHHHHHHHHCCEEEEEHHHHCHHHHHHHHHCCCCCCCCCHHHHHHHH
KENQVNILIDASHPYALEVTKNAREVSKDLNIEYVRYERPSSAEEFKENKKVVFLEDYKD
HCCCEEEEEECCCCEEEEECCCHHHHHHCCCEEEEEECCCCCHHHHHHCCCEEEEHHHHH
LNEALKNIKGNILNTSGSRNMDKILDLKLENRIIHRVLPSVKVLEDCFNLGVKVEDLMAI
HHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHH
KGPISKELNKAFIKDYDAKALILKDSGPQGGTEEKILACLECDIYALVIKRKKINYEREF
CCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHCCHHEEEHHHHHCCHHHHC
NNIEILVEYISSMIN
CHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 6B; NADP+

Specific reaction: precorrin-6B + NADP+ = precorrin-6A + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]