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The map label for this gene is resE [H]

Identifier: 153934988

GI number: 153934988

Start: 382040

End: 383887

Strand: Direct

Name: resE [H]

Synonym: CLC_0394

Alternate gene names: 153934988

Gene position: 382040-383887 (Clockwise)

Preceding gene: 153936600

Following gene: 153934648

Centisome position: 10.16

GC content: 24.3

Gene sequence:

>1848_bases
ATGAACTTAGATAAAATAGAAATTAGAAATTGGAGTCATGATAAAAAAATATATAATAGCATGTTAATAGTAAAATTCAT
TATACTGCTTTTTTGCGGAGGTGCTATTTATTTAGATTATGCAGAAAAGAATAATAAGAATATTTCTCAAAACTTTTATT
GTAATGCATTAAATCTAGTTATTATAATAATATGTTTAGTTAGTGTATATTTTATTTGGATGTTTATATCAATAAAGGCT
TTTAAATTTGAAAGAATAAAAACAATTCAAGTTATAGAAAATACTATATCAATTGTAATTTTTACATTTATAATAATGAT
GTCGGGAAGCTATAAGAGCTCTTATAAATTTCTATTTTTAGTAGCTATAATCACTGCTACAATACAATTGGGAATGAAAC
ATGGAATTATTACGTCACTTGTATCCTCTATTATAATATTATCCATAGATCTAATATTAGCACCAAAGGCTCCAGTAAAT
ATATATTTTGAAACAGATTTAATTTTAGTAGGAGTTTTCATAATGACAGCTTGGCCCTTGGGGTATTATGTTAATATTCA
AAAGGAAGATCTAAGACAAAAAGAGGAAGAAGTAAATATATTAGCTAATAAATTAGACCAGAAAGAAATGCAAAAAAGAT
GTATGGAGCAATTACTTATAAAAAATGAAAATTGTTATAATTTACTTATAAGAAATTCAAAGGATGCTATATTGGTACAT
AGATATGGTAAGATTATATTTGCTAATGAAAGATTAAAGCAGATGTTAGGATACAAAAAAGAATATAATTTTGAGGATAT
AGATATAAAAAGTTTAATACCTAAAGATGAATATAATACTGTAAAAAATAAGTTGGAAAACTTATATTACGGTAGTGAAA
ATGTAGTTAATTTTCAGCACAATGTAATTAATAATAAAGAGAAGACAATACAAAATACATCTACCTATGTTATATATGAT
GGAATGCCAACAATTTTCAGTATATTACATGATGTAACATCTAAAATACAAGTAGAAAAATTTGAACAAGATGTTAAAAA
GAATATAGAATTGCTAAATGAAAGTAGAGAGTATAATAAATTAATTACAGAGTTTTTATCTAATATATCCCATGAGTTAA
AAACTCCTTTAAATGTTATTTTTACAGCAGTGCAATTATTGGGTTTTTATGAAAAGGATGTTGACTATGAAAAACAAGAT
AAATATTTAAAACTAATAAAGCAGAATTGTTATAGGCTTATGAAGTTGATAAATAACCTATTAGATACAACAAAATTAGA
TTCAGGATATTTAAAATTAAATTTAGTTAATTATAATATAGTAAATTTAATAGAAGAAATAACATTATCTGTAACATCCT
ACGCTGAAAGTAAGGGGATAAATATTATATTTGATACAAATGTGGAAGAGAAAATCATTGCTGTTGATACAGATAAAATA
GAAAGAATTATTTTAAATTTACTTTCAAACTCTATAAAGTTTACTAATCCCGGAGGTAATATATTTGTAAATGTAAAAGA
TTGTGGAGAGAATGTATATGTACATGTAAAAGACACGGGAGTTGGTATACCTTCGGATAAATTAGAATCTATATTTGAAA
GATTTTTTCAAGTAGATAAAACTTTAAAGAAAAATAAAGAGGGAACTGGTATAGGATTACATTTAGTAAAATCCTTTGTA
GAAATGCATAATGGTACTGTTCATATAAAAAGTGAATTAGGACAAGGAACAGAATTTATAATAAAGTTACCTGCTGTAGT
TTGTGAGGAACAGATAAAATCAAAAAATATAGTTTATGAAGCTAATATAGAACGTATAAATATGGAATTTTCAGATATAA
ATCAATAG

Upstream 100 bases:

>100_bases
ATTTTATTCCTTCATTTACTTTATTTGTATTTAGTGTTTTTACTATGAACAAATTTATAAATAGAGAGGAATAATGTAAA
AATATATAGGAGTTATGTTA

Downstream 100 bases:

>100_bases
ATAATAATTATTTATGAAATAAATTTTTTAAAATTGCATACTACAATTTTAGAGAATTTATTTTATTTTTATCTATTAAA
ATTTATATAGACTCACAAGT

Product: sensory box histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 615; Mature: 615

Protein sequence:

>615_residues
MNLDKIEIRNWSHDKKIYNSMLIVKFIILLFCGGAIYLDYAEKNNKNISQNFYCNALNLVIIIICLVSVYFIWMFISIKA
FKFERIKTIQVIENTISIVIFTFIIMMSGSYKSSYKFLFLVAIITATIQLGMKHGIITSLVSSIIILSIDLILAPKAPVN
IYFETDLILVGVFIMTAWPLGYYVNIQKEDLRQKEEEVNILANKLDQKEMQKRCMEQLLIKNENCYNLLIRNSKDAILVH
RYGKIIFANERLKQMLGYKKEYNFEDIDIKSLIPKDEYNTVKNKLENLYYGSENVVNFQHNVINNKEKTIQNTSTYVIYD
GMPTIFSILHDVTSKIQVEKFEQDVKKNIELLNESREYNKLITEFLSNISHELKTPLNVIFTAVQLLGFYEKDVDYEKQD
KYLKLIKQNCYRLMKLINNLLDTTKLDSGYLKLNLVNYNIVNLIEEITLSVTSYAESKGINIIFDTNVEEKIIAVDTDKI
ERIILNLLSNSIKFTNPGGNIFVNVKDCGENVYVHVKDTGVGIPSDKLESIFERFFQVDKTLKKNKEGTGIGLHLVKSFV
EMHNGTVHIKSELGQGTEFIIKLPAVVCEEQIKSKNIVYEANIERINMEFSDINQ

Sequences:

>Translated_615_residues
MNLDKIEIRNWSHDKKIYNSMLIVKFIILLFCGGAIYLDYAEKNNKNISQNFYCNALNLVIIIICLVSVYFIWMFISIKA
FKFERIKTIQVIENTISIVIFTFIIMMSGSYKSSYKFLFLVAIITATIQLGMKHGIITSLVSSIIILSIDLILAPKAPVN
IYFETDLILVGVFIMTAWPLGYYVNIQKEDLRQKEEEVNILANKLDQKEMQKRCMEQLLIKNENCYNLLIRNSKDAILVH
RYGKIIFANERLKQMLGYKKEYNFEDIDIKSLIPKDEYNTVKNKLENLYYGSENVVNFQHNVINNKEKTIQNTSTYVIYD
GMPTIFSILHDVTSKIQVEKFEQDVKKNIELLNESREYNKLITEFLSNISHELKTPLNVIFTAVQLLGFYEKDVDYEKQD
KYLKLIKQNCYRLMKLINNLLDTTKLDSGYLKLNLVNYNIVNLIEEITLSVTSYAESKGINIIFDTNVEEKIIAVDTDKI
ERIILNLLSNSIKFTNPGGNIFVNVKDCGENVYVHVKDTGVGIPSDKLESIFERFFQVDKTLKKNKEGTGIGLHLVKSFV
EMHNGTVHIKSELGQGTEFIIKLPAVVCEEQIKSKNIVYEANIERINMEFSDINQ
>Mature_615_residues
MNLDKIEIRNWSHDKKIYNSMLIVKFIILLFCGGAIYLDYAEKNNKNISQNFYCNALNLVIIIICLVSVYFIWMFISIKA
FKFERIKTIQVIENTISIVIFTFIIMMSGSYKSSYKFLFLVAIITATIQLGMKHGIITSLVSSIIILSIDLILAPKAPVN
IYFETDLILVGVFIMTAWPLGYYVNIQKEDLRQKEEEVNILANKLDQKEMQKRCMEQLLIKNENCYNLLIRNSKDAILVH
RYGKIIFANERLKQMLGYKKEYNFEDIDIKSLIPKDEYNTVKNKLENLYYGSENVVNFQHNVINNKEKTIQNTSTYVIYD
GMPTIFSILHDVTSKIQVEKFEQDVKKNIELLNESREYNKLITEFLSNISHELKTPLNVIFTAVQLLGFYEKDVDYEKQD
KYLKLIKQNCYRLMKLINNLLDTTKLDSGYLKLNLVNYNIVNLIEEITLSVTSYAESKGINIIFDTNVEEKIIAVDTDKI
ERIILNLLSNSIKFTNPGGNIFVNVKDCGENVYVHVKDTGVGIPSDKLESIFERFFQVDKTLKKNKEGTGIGLHLVKSFV
EMHNGTVHIKSELGQGTEFIIKLPAVVCEEQIKSKNIVYEANIERINMEFSDINQ

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=307, Percent_Identity=28.3387622149837, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1789149, Length=295, Percent_Identity=27.1186440677966, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI48994928, Length=471, Percent_Identity=24.8407643312102, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1790436, Length=236, Percent_Identity=29.2372881355932, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1786783, Length=224, Percent_Identity=29.4642857142857, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1786912, Length=250, Percent_Identity=28, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788713, Length=260, Percent_Identity=25.7692307692308, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1788393, Length=253, Percent_Identity=24.1106719367589, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI87081816, Length=259, Percent_Identity=27.4131274131274, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1786600, Length=221, Percent_Identity=25.3393665158371, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI87082128, Length=226, Percent_Identity=29.2035398230088, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1788549, Length=396, Percent_Identity=21.7171717171717, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1790861, Length=210, Percent_Identity=27.6190476190476, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790300, Length=232, Percent_Identity=25.8620689655172, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1790346, Length=248, Percent_Identity=25.8064516129032, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787894, Length=222, Percent_Identity=26.5765765765766, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1787374, Length=219, Percent_Identity=28.310502283105, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322044, Length=251, Percent_Identity=29.4820717131474, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71141; Mature: 71141

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLDKIEIRNWSHDKKIYNSMLIVKFIILLFCGGAIYLDYAEKNNKNISQNFYCNALNLV
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHH
IIIICLVSVYFIWMFISIKAFKFERIKTIQVIENTISIVIFTFIIMMSGSYKSSYKFLFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VAIITATIQLGMKHGIITSLVSSIIILSIDLILAPKAPVNIYFETDLILVGVFIMTAWPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECHHHHHHHHHHHHCCC
GYYVNIQKEDLRQKEEEVNILANKLDQKEMQKRCMEQLLIKNENCYNLLIRNSKDAILVH
CEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEE
RYGKIIFANERLKQMLGYKKEYNFEDIDIKSLIPKDEYNTVKNKLENLYYGSENVVNFQH
ECCCEEEECHHHHHHHCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEHH
NVINNKEKTIQNTSTYVIYDGMPTIFSILHDVTSKIQVEKFEQDVKKNIELLNESREYNK
HHCCCHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LITEFLSNISHELKTPLNVIFTAVQLLGFYEKDVDYEKQDKYLKLIKQNCYRLMKLINNL
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LDTTKLDSGYLKLNLVNYNIVNLIEEITLSVTSYAESKGINIIFDTNVEEKIIAVDTDKI
HHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEECHHHH
ERIILNLLSNSIKFTNPGGNIFVNVKDCGENVYVHVKDTGVGIPSDKLESIFERFFQVDK
HHHHHHHHHCCCEEECCCCEEEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHH
TLKKNKEGTGIGLHLVKSFVEMHNGTVHIKSELGQGTEFIIKLPAVVCEEQIKSKNIVYE
HHHCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEECHHHHHHHHHCCCCEEEE
ANIERINMEFSDINQ
ECCEEEECCHHCCCC
>Mature Secondary Structure
MNLDKIEIRNWSHDKKIYNSMLIVKFIILLFCGGAIYLDYAEKNNKNISQNFYCNALNLV
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHH
IIIICLVSVYFIWMFISIKAFKFERIKTIQVIENTISIVIFTFIIMMSGSYKSSYKFLFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VAIITATIQLGMKHGIITSLVSSIIILSIDLILAPKAPVNIYFETDLILVGVFIMTAWPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECHHHHHHHHHHHHCCC
GYYVNIQKEDLRQKEEEVNILANKLDQKEMQKRCMEQLLIKNENCYNLLIRNSKDAILVH
CEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEE
RYGKIIFANERLKQMLGYKKEYNFEDIDIKSLIPKDEYNTVKNKLENLYYGSENVVNFQH
ECCCEEEECHHHHHHHCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEHH
NVINNKEKTIQNTSTYVIYDGMPTIFSILHDVTSKIQVEKFEQDVKKNIELLNESREYNK
HHCCCHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LITEFLSNISHELKTPLNVIFTAVQLLGFYEKDVDYEKQDKYLKLIKQNCYRLMKLINNL
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LDTTKLDSGYLKLNLVNYNIVNLIEEITLSVTSYAESKGINIIFDTNVEEKIIAVDTDKI
HHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEECHHHH
ERIILNLLSNSIKFTNPGGNIFVNVKDCGENVYVHVKDTGVGIPSDKLESIFERFFQVDK
HHHHHHHHHCCCEEECCCCEEEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHH
TLKKNKEGTGIGLHLVKSFVEMHNGTVHIKSELGQGTEFIIKLPAVVCEEQIKSKNIVYE
HHHCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEECHHHHHHHHHCCCCEEEE
ANIERINMEFSDINQ
ECCEEEECCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]