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The map label for this gene is dctR [H]

Identifier: 153934977

GI number: 153934977

Start: 289346

End: 290020

Strand: Direct

Name: dctR [H]

Synonym: CLC_0307

Alternate gene names: 153934977

Gene position: 289346-290020 (Clockwise)

Preceding gene: 153935941

Following gene: 153936614

Centisome position: 7.69

GC content: 26.07

Gene sequence:

>675_bases
TTGATTCAGGTAATGATAGTTGAAGATGATCCTATGGTTAGAGAAATAAATTCTAAATTTTTAAAAAGAGTAGAAGGATT
TGTTTTGTATAAAGCAGTTTCCAATCTTTATGACGCTAAAAAATTTATAGCCATGAAAAAGCCAGATCTTATATTACTTG
ATGTATATCTTCCTAAAGAAAATGGTATTGATCTTTTGAAGTGGATAAGAAAGCAAGATATAGATATAGATATTATCTTA
ATTACAGCAGATAAATCTATTGAAAGAATACAAGAAGCCTTTAGGAGTGGGGTTGTAGATTATCTTATAAAACCCTTTAA
CTTTGAAAGATTTAAAGAATCACTTATTCAATTTAAGGGTAGATATTATGAATTTAAAAAAAATAATGTAATTGAACAAA
AAGATTTAGATAAAATAATATGTAGTTCTAATATATCTCAAAATGAAGATGACTTTGCTAAAGGGCTTAATAAATACACT
TATAAATCTATATGGAATGAAATAGAAAAAAGTAATGATAAGGATTTTACAGCAGAATATTTAGCAGAAAAACTAGGAAT
AGCCAGAGTAACAGTTAGAAGATATCTCGAATATATGGAAAAAGAAAATAAAGTATATAAATTGGTGGAATATGGGAAGG
TAGGTAGACCACAACATAAATATCACAAAATTTAA

Upstream 100 bases:

>100_bases
GTAAAAAAAATAATTGATGAGACTAAAGGAACAATAAGACTTGATGTGGACAACGGTGTTATTTGGAATATAACTATACC
GATGACAAGGGGTGATAAAA

Downstream 100 bases:

>100_bases
TAAAAATAAAATAATTGGTGTAAAAGGTGATGAAGAATTATTAGTCAGGGGTATTAACAATATTTTAAAGTATTTAAAAA
ATGGAGTAGTTATTATATAA

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MIQVMIVEDDPMVREINSKFLKRVEGFVLYKAVSNLYDAKKFIAMKKPDLILLDVYLPKENGIDLLKWIRKQDIDIDIIL
ITADKSIERIQEAFRSGVVDYLIKPFNFERFKESLIQFKGRYYEFKKNNVIEQKDLDKIICSSNISQNEDDFAKGLNKYT
YKSIWNEIEKSNDKDFTAEYLAEKLGIARVTVRRYLEYMEKENKVYKLVEYGKVGRPQHKYHKI

Sequences:

>Translated_224_residues
MIQVMIVEDDPMVREINSKFLKRVEGFVLYKAVSNLYDAKKFIAMKKPDLILLDVYLPKENGIDLLKWIRKQDIDIDIIL
ITADKSIERIQEAFRSGVVDYLIKPFNFERFKESLIQFKGRYYEFKKNNVIEQKDLDKIICSSNISQNEDDFAKGLNKYT
YKSIWNEIEKSNDKDFTAEYLAEKLGIARVTVRRYLEYMEKENKVYKLVEYGKVGRPQHKYHKI
>Mature_224_residues
MIQVMIVEDDPMVREINSKFLKRVEGFVLYKAVSNLYDAKKFIAMKKPDLILLDVYLPKENGIDLLKWIRKQDIDIDIIL
ITADKSIERIQEAFRSGVVDYLIKPFNFERFKESLIQFKGRYYEFKKNNVIEQKDLDKIICSSNISQNEDDFAKGLNKYT
YKSIWNEIEKSNDKDFTAEYLAEKLGIARVTVRRYLEYMEKENKVYKLVEYGKVGRPQHKYHKI

Specific function: Member of the two-component regulatory system dctS/dctR. Essential for expression of dctP [H]

COG id: COG4565

COG function: function code KT; Response regulator of citrate/malate metabolism

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790566, Length=226, Percent_Identity=35.3982300884956, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1786838, Length=222, Percent_Identity=33.7837837837838, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=33.9449541284404, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 26663; Mature: 26663

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQVMIVEDDPMVREINSKFLKRVEGFVLYKAVSNLYDAKKFIAMKKPDLILLDVYLPKE
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCC
NGIDLLKWIRKQDIDIDIILITADKSIERIQEAFRSGVVDYLIKPFNFERFKESLIQFKG
CCHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHCC
RYYEFKKNNVIEQKDLDKIICSSNISQNEDDFAKGLNKYTYKSIWNEIEKSNDKDFTAEY
HHEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LAEKLGIARVTVRRYLEYMEKENKVYKLVEYGKVGRPQHKYHKI
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHCCC
>Mature Secondary Structure
MIQVMIVEDDPMVREINSKFLKRVEGFVLYKAVSNLYDAKKFIAMKKPDLILLDVYLPKE
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCC
NGIDLLKWIRKQDIDIDIILITADKSIERIQEAFRSGVVDYLIKPFNFERFKESLIQFKG
CCHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHCC
RYYEFKKNNVIEQKDLDKIICSSNISQNEDDFAKGLNKYTYKSIWNEIEKSNDKDFTAEY
HHEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LAEKLGIARVTVRRYLEYMEKENKVYKLVEYGKVGRPQHKYHKI
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA