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The map label for this gene is atoD [H]

Identifier: 153934896

GI number: 153934896

Start: 2874465

End: 2875181

Strand: Direct

Name: atoD [H]

Synonym: CLC_2723

Alternate gene names: 153934896

Gene position: 2874465-2875181 (Clockwise)

Preceding gene: 153937260

Following gene: 153935593

Centisome position: 76.44

GC content: 35.01

Gene sequence:

>717_bases
ATGACAAAGATTAAGACAATACAAGAAGCAGTAGAAAATATTAAAGATGGAATGAAAATTATGGCGGCAGGTTTTTTAGG
AGTAGGTGCTCCACTAAAGATGATAGATGCATTAGCAGAGACAAATGTTAAAGACCTTACACTTATTCAACCTGTATCAG
CTCACCCAGGACAAACTCACGATATTGGCAAGCTTGTAGCAAATAAACAAATAAAAAAGTTTATAGGTTCACATATTGGA
ACTTGCCCTGAAATACAAGAACAATACAATGCAGGTACATTAGAAGTTGAATTTATACCTATGGGAACTATAGTAGAATG
TATAAGAGCTGGTGGAGCTGGACTTGGCGCAGTTGTAACTCCAACTGGTATTGGAACTGAAATTGAAAAGGGAAGAGATA
AACTTACTATAGATGGAAAGGAATATTTAGTATTTCCACCAATAAAGGCAGATGTTGCGATAATCAAGGGGTATAAAGCT
GATAAACTTGGGAATATCGTATATAGAGGAACAACTAAAGGAGCAAATACAAATATGGCACTTGCAGCTGATTTAGTTAT
AGCTGAAGTAGATGAAATTGTAGAAGTGGGTGAAATTTCACCTGATAGTATTGGAACACCAGGAATATTGGTAGATATAA
TAGTTCAAGGAGACTCTTTTGGAGAGAGGAAAAAATATTTTGAAGATTTATGGGTAGCAACTAACAAAATGAAATAG

Upstream 100 bases:

>100_bases
AGGAATAATAATAATGTAAGAATTAAATTTCTAATATAGAGGTATTATTCAAAAAAAATAGTCCATGTTAGATTATAGAA
CTTTGGAGGTATATAGAAAA

Downstream 100 bases:

>100_bases
GGGGAGAAATGATGAATAGTAAAGAGATAATTGCAAGAAGAATCGCGAAAGAGTTTAAAGAGGGAATGGTTGCTAATTTA
GGATTCGGTATACCCAATAT

Product: CoA-transferase, A subunit

Products: NA

Alternate protein names: Acetyl-CoA:acetoacetate-CoA transferase subunit alpha [H]

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MTKIKTIQEAVENIKDGMKIMAAGFLGVGAPLKMIDALAETNVKDLTLIQPVSAHPGQTHDIGKLVANKQIKKFIGSHIG
TCPEIQEQYNAGTLEVEFIPMGTIVECIRAGGAGLGAVVTPTGIGTEIEKGRDKLTIDGKEYLVFPPIKADVAIIKGYKA
DKLGNIVYRGTTKGANTNMALAADLVIAEVDEIVEVGEISPDSIGTPGILVDIIVQGDSFGERKKYFEDLWVATNKMK

Sequences:

>Translated_238_residues
MTKIKTIQEAVENIKDGMKIMAAGFLGVGAPLKMIDALAETNVKDLTLIQPVSAHPGQTHDIGKLVANKQIKKFIGSHIG
TCPEIQEQYNAGTLEVEFIPMGTIVECIRAGGAGLGAVVTPTGIGTEIEKGRDKLTIDGKEYLVFPPIKADVAIIKGYKA
DKLGNIVYRGTTKGANTNMALAADLVIAEVDEIVEVGEISPDSIGTPGILVDIIVQGDSFGERKKYFEDLWVATNKMK
>Mature_237_residues
TKIKTIQEAVENIKDGMKIMAAGFLGVGAPLKMIDALAETNVKDLTLIQPVSAHPGQTHDIGKLVANKQIKKFIGSHIGT
CPEIQEQYNAGTLEVEFIPMGTIVECIRAGGAGLGAVVTPTGIGTEIEKGRDKLTIDGKEYLVFPPIKADVAIIKGYKAD
KLGNIVYRGTTKGANTNMALAADLVIAEVDEIVEVGEISPDSIGTPGILVDIIVQGDSFGERKKYFEDLWVATNKMK

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=234, Percent_Identity=36.7521367521368, Blast_Score=154, Evalue=7e-38,
Organism=Homo sapiens, GI11545841, Length=234, Percent_Identity=38.8888888888889, Blast_Score=144, Evalue=7e-35,
Organism=Escherichia coli, GI1788551, Length=219, Percent_Identity=45.662100456621, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI1787985, Length=238, Percent_Identity=24.7899159663866, Blast_Score=60, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17531517, Length=238, Percent_Identity=36.1344537815126, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI21358325, Length=235, Percent_Identity=37.8723404255319, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24655794, Length=235, Percent_Identity=37.8723404255319, Blast_Score=149, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.8 [H]

Molecular weight: Translated: 25408; Mature: 25277

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIKTIQEAVENIKDGMKIMAAGFLGVGAPLKMIDALAETNVKDLTLIQPVSAHPGQTH
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCH
DIGKLVANKQIKKFIGSHIGTCPEIQEQYNAGTLEVEFIPMGTIVECIRAGGAGLGAVVT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEEECHHHHHHHHHCCCCCCCEEEC
PTGIGTEIEKGRDKLTIDGKEYLVFPPIKADVAIIKGYKADKLGNIVYRGTTKGANTNMA
CCCCCCHHHCCCCEEEECCCEEEEECCCCCCCCEECCCCCCCCCCEEEECCCCCCCCCHH
LAADLVIAEVDEIVEVGEISPDSIGTPGILVDIIVQGDSFGERKKYFEDLWVATNKMK
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKIKTIQEAVENIKDGMKIMAAGFLGVGAPLKMIDALAETNVKDLTLIQPVSAHPGQTH
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCH
DIGKLVANKQIKKFIGSHIGTCPEIQEQYNAGTLEVEFIPMGTIVECIRAGGAGLGAVVT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEEECHHHHHHHHHCCCCCCCEEEC
PTGIGTEIEKGRDKLTIDGKEYLVFPPIKADVAIIKGYKADKLGNIVYRGTTKGANTNMA
CCCCCCHHHCCCCEEEECCCEEEEECCCCCCCCEECCCCCCCCCCEEEECCCCCCCCCHH
LAADLVIAEVDEIVEVGEISPDSIGTPGILVDIIVQGDSFGERKKYFEDLWVATNKMK
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]