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The map label for this gene is rnr [H]

Identifier: 153934693

GI number: 153934693

Start: 267124

End: 269301

Strand: Direct

Name: rnr [H]

Synonym: CLC_0288

Alternate gene names: 153934693

Gene position: 267124-269301 (Clockwise)

Preceding gene: 153937200

Following gene: 153935686

Centisome position: 7.1

GC content: 29.84

Gene sequence:

>2178_bases
ATGAATATAAGAGAAACAATATTAGCTTTTATGGAAGAACAGGCATATAAACCTATGGATATAAAAGAATTAAAGCAGGT
GTTTGGAGTAACTAAACATGAATACAAGGAATTTGAGAAAATGTTAAAGGATATGGAAAAAGACGGACAAATAGTTAAAA
CAAGAACGGAACATTATGGCATACCGGCCAGAATGGGATTAGTTCTAGGAAAACTTCAAGGACATCAAAAGGGTTTTGGA
TTCGTTATACCAGAAGAAGAAAGAGAAGATATTTTTATACCAGCATCTAGTATGAATGGAGCTATGCATACTGATAGAGT
ATTAGCTAAAATTACTAAAGAATCAGCTAATGGAAAAAGATGCGAAGGTGAAATAATAAGAATATTAGAAAGAGGCAATA
AAACAGTCATAGGCATATACGAAGATAGTAAAAACTTTGGTTTTGTGGTTTCCGATGATAAAAAGATATACCAAGACATA
TTTATACCAAAGGGAGATAAAAATGGAGCAAAAACAGGTCAAGTAGTTATAGCAGAAATTGTAACCTATCCAGAAAAGAG
AAGAAATCCTGAAGGAAGAGTTATAGAAATATTAGGTAATAAAGAAGATAAGGGTATAGATATATTAACCATAATAAAGA
AAAATAAATTACCAGAGGAATTCCCACCAAAGGTACAAAGTTATGCAGACAATATATCAGAAGCAATTCCAGAAGAAGAG
TATAAAAGAAGGGAAGACTTAAGAGATTTAACTATTGTTACTATAGATGGAGAGGATGCTAAGGATTTAGATGATGCTAT
ATCTTTAGAAAAACTACCAAATGGAAACTATTATTTAGGAGTACATATAGCAGATGTATCTCACTATGTAAAAGAGAAAA
ATCCACTAGACAAAGAAGCTTTAAAAAGAGCAACTTCAGTATATCTTATAGATAGGGTAATACCAATGTTACCTAAAAAA
CTTTCTAATGGAATATGTAGTTTGAATCCTAAAATTGATAGATTAACCTTAAGCTGTTTTATGGAAATAGATAAAAATGG
TAAGGTAGTAGATCATAGAGTGGTAGAAAGTATAATAAAAAGCACTGAAAGAATGACCTATACAGATGTGACTAAAATAC
TAAGAGATGAAGATGAGGAAACTATAAATAAATATAGCAATTTAGTGGATTATTTCAAACTTATGGAGGAACTTTGCAAA
ATACTTTACAAGAAAAGATTAAAAAGAGGAGCTATAGATTTCGATTTTGAGGAATGTAAAATAATATTAGATGAAAAGGG
CAAACCAATAGAGATAAAACCTTATGAAAGAGCTATAGCAAACAGAATAATAGAGGAATTTATGCTTGTTTGTAATGAAA
CCATAGCAGAGCATATGTTCTGGTCCAATTTACCTTTTGTATATAGAATCCACGAAGATCCAGATGAAGAAAAATTAATG
CATTTTAACGAGTTTGTTCATAATCTAGGATATGTTATAAGATGGAACAACGATATTCATCCAAAATCATTGCAAAGTAT
TATAGAAAAAGTAAAAGGGGAAAAAGAAGAAACTGTAGTTAGTACATTGCTTTTACGATCATTAAAACAAGCAAGATACT
CTCCAGAATGTATAGGACACTTTGGATTAGCTGCAAGATATTACTGTCACTTTACTTCACCAATAAGAAGATATCCAGAC
CTTATCATACACAGGATAATAAAAGAATATATAAATGGACAGATTGATGATAAAAGAGCTACAAAGCTTACAACAGAAGT
AGAATATGCTTCTAAACAATCTTCAGAAATGGAAAGGGTAGCTCAAGAAGCTGAAAGAGAAGTAGATGATTTAAAGAAAG
CAGAATATATGAGTGAAAGAATAGGGGAAGAATACGAAGGAATAATATCTTCAGTAACTAATTTTGGAATGTTTGTAGAA
CTACCAAATACAATAGAAGGATTAGTTCATATAAGCACACTATCTGATGATTACTATATATATGATGAAAGACGATTAAG
TTTAATTGGAGAAGCTAGCAAAAATATATATAGATTAGGAGATACAGTAAAAATTAAAGTTTCAAAAGTAGATTTATTTA
GTCATGAAATATATTTTGATATTATAAAAGATAATGAAGAAGACAAAGAAGAGGTTGAATTTATAGAGGAAACAGAAAAG
TATAATACTAATTTATAA

Upstream 100 bases:

>100_bases
TATGATATAAATAACATATAAAAATCATTAATTGTATTATAAAAAATAGATTAATGCTTAGAATATATGTTATAAGCCTT
TAATTAGTAGGAGGGATTTT

Downstream 100 bases:

>100_bases
GTTAAAAATTATTTAAGAGAAACTCAGTTTAAAGTTAATGCTGAGTTTCTCTTATAAGTTTTAAAAGATATATATTATAT
TTTATAGATACAATTTAATT

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 725; Mature: 725

Protein sequence:

>725_residues
MNIRETILAFMEEQAYKPMDIKELKQVFGVTKHEYKEFEKMLKDMEKDGQIVKTRTEHYGIPARMGLVLGKLQGHQKGFG
FVIPEEEREDIFIPASSMNGAMHTDRVLAKITKESANGKRCEGEIIRILERGNKTVIGIYEDSKNFGFVVSDDKKIYQDI
FIPKGDKNGAKTGQVVIAEIVTYPEKRRNPEGRVIEILGNKEDKGIDILTIIKKNKLPEEFPPKVQSYADNISEAIPEEE
YKRREDLRDLTIVTIDGEDAKDLDDAISLEKLPNGNYYLGVHIADVSHYVKEKNPLDKEALKRATSVYLIDRVIPMLPKK
LSNGICSLNPKIDRLTLSCFMEIDKNGKVVDHRVVESIIKSTERMTYTDVTKILRDEDEETINKYSNLVDYFKLMEELCK
ILYKKRLKRGAIDFDFEECKIILDEKGKPIEIKPYERAIANRIIEEFMLVCNETIAEHMFWSNLPFVYRIHEDPDEEKLM
HFNEFVHNLGYVIRWNNDIHPKSLQSIIEKVKGEKEETVVSTLLLRSLKQARYSPECIGHFGLAARYYCHFTSPIRRYPD
LIIHRIIKEYINGQIDDKRATKLTTEVEYASKQSSEMERVAQEAEREVDDLKKAEYMSERIGEEYEGIISSVTNFGMFVE
LPNTIEGLVHISTLSDDYYIYDERRLSLIGEASKNIYRLGDTVKIKVSKVDLFSHEIYFDIIKDNEEDKEEVEFIEETEK
YNTNL

Sequences:

>Translated_725_residues
MNIRETILAFMEEQAYKPMDIKELKQVFGVTKHEYKEFEKMLKDMEKDGQIVKTRTEHYGIPARMGLVLGKLQGHQKGFG
FVIPEEEREDIFIPASSMNGAMHTDRVLAKITKESANGKRCEGEIIRILERGNKTVIGIYEDSKNFGFVVSDDKKIYQDI
FIPKGDKNGAKTGQVVIAEIVTYPEKRRNPEGRVIEILGNKEDKGIDILTIIKKNKLPEEFPPKVQSYADNISEAIPEEE
YKRREDLRDLTIVTIDGEDAKDLDDAISLEKLPNGNYYLGVHIADVSHYVKEKNPLDKEALKRATSVYLIDRVIPMLPKK
LSNGICSLNPKIDRLTLSCFMEIDKNGKVVDHRVVESIIKSTERMTYTDVTKILRDEDEETINKYSNLVDYFKLMEELCK
ILYKKRLKRGAIDFDFEECKIILDEKGKPIEIKPYERAIANRIIEEFMLVCNETIAEHMFWSNLPFVYRIHEDPDEEKLM
HFNEFVHNLGYVIRWNNDIHPKSLQSIIEKVKGEKEETVVSTLLLRSLKQARYSPECIGHFGLAARYYCHFTSPIRRYPD
LIIHRIIKEYINGQIDDKRATKLTTEVEYASKQSSEMERVAQEAEREVDDLKKAEYMSERIGEEYEGIISSVTNFGMFVE
LPNTIEGLVHISTLSDDYYIYDERRLSLIGEASKNIYRLGDTVKIKVSKVDLFSHEIYFDIIKDNEEDKEEVEFIEETEK
YNTNL
>Mature_725_residues
MNIRETILAFMEEQAYKPMDIKELKQVFGVTKHEYKEFEKMLKDMEKDGQIVKTRTEHYGIPARMGLVLGKLQGHQKGFG
FVIPEEEREDIFIPASSMNGAMHTDRVLAKITKESANGKRCEGEIIRILERGNKTVIGIYEDSKNFGFVVSDDKKIYQDI
FIPKGDKNGAKTGQVVIAEIVTYPEKRRNPEGRVIEILGNKEDKGIDILTIIKKNKLPEEFPPKVQSYADNISEAIPEEE
YKRREDLRDLTIVTIDGEDAKDLDDAISLEKLPNGNYYLGVHIADVSHYVKEKNPLDKEALKRATSVYLIDRVIPMLPKK
LSNGICSLNPKIDRLTLSCFMEIDKNGKVVDHRVVESIIKSTERMTYTDVTKILRDEDEETINKYSNLVDYFKLMEELCK
ILYKKRLKRGAIDFDFEECKIILDEKGKPIEIKPYERAIANRIIEEFMLVCNETIAEHMFWSNLPFVYRIHEDPDEEKLM
HFNEFVHNLGYVIRWNNDIHPKSLQSIIEKVKGEKEETVVSTLLLRSLKQARYSPECIGHFGLAARYYCHFTSPIRRYPD
LIIHRIIKEYINGQIDDKRATKLTTEVEYASKQSSEMERVAQEAEREVDDLKKAEYMSERIGEEYEGIISSVTNFGMFVE
LPNTIEGLVHISTLSDDYYIYDERRLSLIGEASKNIYRLGDTVKIKVSKVDLFSHEIYFDIIKDNEEDKEEVEFIEETEK
YNTNL

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014623, Length=600, Percent_Identity=28.3333333333333, Blast_Score=216, Evalue=6e-56,
Organism=Homo sapiens, GI190014625, Length=600, Percent_Identity=28.3333333333333, Blast_Score=216, Evalue=6e-56,
Organism=Homo sapiens, GI134288890, Length=373, Percent_Identity=32.171581769437, Blast_Score=194, Evalue=4e-49,
Organism=Homo sapiens, GI19115966, Length=512, Percent_Identity=26.7578125, Blast_Score=159, Evalue=9e-39,
Organism=Homo sapiens, GI219521928, Length=585, Percent_Identity=25.982905982906, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI156105695, Length=444, Percent_Identity=23.6486486486486, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI156105693, Length=213, Percent_Identity=28.6384976525822, Blast_Score=84, Evalue=7e-16,
Organism=Escherichia coli, GI87082383, Length=708, Percent_Identity=38.2768361581921, Blast_Score=499, Evalue=1e-142,
Organism=Escherichia coli, GI1787542, Length=648, Percent_Identity=26.5432098765432, Blast_Score=176, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI212645896, Length=496, Percent_Identity=28.2258064516129, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17553506, Length=533, Percent_Identity=27.0168855534709, Blast_Score=178, Evalue=8e-45,
Organism=Saccharomyces cerevisiae, GI6324552, Length=614, Percent_Identity=27.3615635179153, Blast_Score=187, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6320499, Length=446, Percent_Identity=24.8878923766816, Blast_Score=112, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6323943, Length=360, Percent_Identity=25.5555555555556, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24649634, Length=546, Percent_Identity=30.5860805860806, Blast_Score=231, Evalue=1e-60,
Organism=Drosophila melanogaster, GI19922976, Length=458, Percent_Identity=31.4410480349345, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24654597, Length=458, Percent_Identity=31.4410480349345, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24654592, Length=458, Percent_Identity=31.4410480349345, Blast_Score=193, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 84173; Mature: 84173

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRETILAFMEEQAYKPMDIKELKQVFGVTKHEYKEFEKMLKDMEKDGQIVKTRTEHYG
CCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHCC
IPARMGLVLGKLQGHQKGFGFVIPEEEREDIFIPASSMNGAMHTDRVLAKITKESANGKR
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCC
CEGEIIRILERGNKTVIGIYEDSKNFGFVVSDDKKIYQDIFIPKGDKNGAKTGQVVIAEI
CHHHHHHHHHCCCCEEEEEEECCCCCCEEECCCHHHHHHHCCCCCCCCCCCCHHHHHHHH
VTYPEKRRNPEGRVIEILGNKEDKGIDILTIIKKNKLPEEFPPKVQSYADNISEAIPEEE
HHCCHHHCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHH
YKRREDLRDLTIVTIDGEDAKDLDDAISLEKLPNGNYYLGVHIADVSHYVKEKNPLDKEA
HHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCEEEEEEEHHHHHHHHCCCCCCHHH
LKRATSVYLIDRVIPMLPKKLSNGICSLNPKIDRLTLSCFMEIDKNGKVVDHRVVESIIK
HHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHEEEEHHEEECCCCCCHHHHHHHHHHH
STERMTYTDVTKILRDEDEETINKYSNLVDYFKLMEELCKILYKKRLKRGAIDFDFEECK
HHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHE
IILDEKGKPIEIKPYERAIANRIIEEFMLVCNETIAEHMFWSNLPFVYRIHEDPDEEKLM
EEECCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHH
HFNEFVHNLGYVIRWNNDIHPKSLQSIIEKVKGEKEETVVSTLLLRSLKQARYSPECIGH
HHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
FGLAARYYCHFTSPIRRYPDLIIHRIIKEYINGQIDDKRATKLTTEVEYASKQSSEMERV
HHHHHHHHEEECCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AQEAEREVDDLKKAEYMSERIGEEYEGIISSVTNFGMFVELPNTIEGLVHISTLSDDYYI
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCEEEECCCHHHHHEEEEEECCCEEE
YDERRLSLIGEASKNIYRLGDTVKIKVSKVDLFSHEIYFDIIKDNEEDKEEVEFIEETEK
ECCHHHHHHHHHCCCCEECCCEEEEEEEEEEHHHHHEEEEEECCCCCCHHHHHHHHHHHH
YNTNL
HCCCC
>Mature Secondary Structure
MNIRETILAFMEEQAYKPMDIKELKQVFGVTKHEYKEFEKMLKDMEKDGQIVKTRTEHYG
CCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHCC
IPARMGLVLGKLQGHQKGFGFVIPEEEREDIFIPASSMNGAMHTDRVLAKITKESANGKR
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCC
CEGEIIRILERGNKTVIGIYEDSKNFGFVVSDDKKIYQDIFIPKGDKNGAKTGQVVIAEI
CHHHHHHHHHCCCCEEEEEEECCCCCCEEECCCHHHHHHHCCCCCCCCCCCCHHHHHHHH
VTYPEKRRNPEGRVIEILGNKEDKGIDILTIIKKNKLPEEFPPKVQSYADNISEAIPEEE
HHCCHHHCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHH
YKRREDLRDLTIVTIDGEDAKDLDDAISLEKLPNGNYYLGVHIADVSHYVKEKNPLDKEA
HHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCEEEEEEEHHHHHHHHCCCCCCHHH
LKRATSVYLIDRVIPMLPKKLSNGICSLNPKIDRLTLSCFMEIDKNGKVVDHRVVESIIK
HHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHEEEEHHEEECCCCCCHHHHHHHHHHH
STERMTYTDVTKILRDEDEETINKYSNLVDYFKLMEELCKILYKKRLKRGAIDFDFEECK
HHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHE
IILDEKGKPIEIKPYERAIANRIIEEFMLVCNETIAEHMFWSNLPFVYRIHEDPDEEKLM
EEECCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHH
HFNEFVHNLGYVIRWNNDIHPKSLQSIIEKVKGEKEETVVSTLLLRSLKQARYSPECIGH
HHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
FGLAARYYCHFTSPIRRYPDLIIHRIIKEYINGQIDDKRATKLTTEVEYASKQSSEMERV
HHHHHHHHEEECCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AQEAEREVDDLKKAEYMSERIGEEYEGIISSVTNFGMFVELPNTIEGLVHISTLSDDYYI
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCEEEECCCHHHHHEEEEEECCCEEE
YDERRLSLIGEASKNIYRLGDTVKIKVSKVDLFSHEIYFDIIKDNEEDKEEVEFIEETEK
ECCHHHHHHHHHCCCCEECCCEEEEEEEEEEHHHHHEEEEEECCCCCCHHHHHHHHHHHH
YNTNL
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]