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The map label for this gene is plsC [H]

Identifier: 153934628

GI number: 153934628

Start: 480686

End: 481408

Strand: Direct

Name: plsC [H]

Synonym: CLC_0482

Alternate gene names: 153934628

Gene position: 480686-481408 (Clockwise)

Preceding gene: 153936387

Following gene: 153935335

Centisome position: 12.78

GC content: 30.01

Gene sequence:

>723_bases
ATGAAATCACTTATTTTTTATTTAGGTTTTGCACTTTATATGCTGCTGTCTCTTTTGCGAATAATAAAATTGAAACATTT
AAAAAGAAAAGGTAATAAAGAAGAAATAGATAGATATATTAATAAAAGTGTTGTAGGTTGGGCAAAATTCATAGTCAATG
GTATAGGAATAAAAATAAATAAAAAAGGATTAGAGAATGTACCTGATGGGCCTTGTCTGTTTGTAGGAAACCATCAAGGA
TTGTTAGATGTGCCGGTTATAGTTTCATCCTTAGATAGATATGTAGGTTTTGTAGCTAAAAAGGAAATGCTAAAACTTAA
AATATTAACTTATTGGATGAAAGAAATGAAATGTGTTTTTATGGATAGACAAAATGTTAGAGCAGCAGTCAAGACCATAA
ATGAAGGTGTAGAAAATTTAAAAAATGGATATAGTATGCTGATATTTCCAGAAGGTACAAGAAGTAGGGGAGAAAATTTA
GGGGAATTTAAAAAGGGAAGTATGAAATTAGGTATAAAAGCAGGGGTACCAATAGTGCCTATAGCTATTGATGGTACCTA
TAATGTACTGGAGGCCAATGGGAAAAAGATAAAAGCTGCGGATGTAGATTTAATAATATGTCCACCGATATATCCTAATG
AACTCTCTAAAGAGGAACAAAATAATTTATCTGTAACTATTAAAGATGTTATACAAAAAGAATTGGAAAGAACAAGAAAT
TAA

Upstream 100 bases:

>100_bases
CATTATTTAATTCTAACATAAATTAACCAAAAGTAGATAAGTTTTTTTATATATATTATAATAGTAAGGTAAAGTTACAT
AATAAAAGGAGAGAATCATA

Downstream 100 bases:

>100_bases
GGGGAGAGTGTCTCAAAATAAATTTAATTTTGAGACATTCTCTTCTTTTTTTTATTATTAAGTAGTTCTTAGTTAAGGTG
GACTTTGATTAGAATAATTA

Product: putative 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MKSLIFYLGFALYMLLSLLRIIKLKHLKRKGNKEEIDRYINKSVVGWAKFIVNGIGIKINKKGLENVPDGPCLFVGNHQG
LLDVPVIVSSLDRYVGFVAKKEMLKLKILTYWMKEMKCVFMDRQNVRAAVKTINEGVENLKNGYSMLIFPEGTRSRGENL
GEFKKGSMKLGIKAGVPIVPIAIDGTYNVLEANGKKIKAADVDLIICPPIYPNELSKEEQNNLSVTIKDVIQKELERTRN

Sequences:

>Translated_240_residues
MKSLIFYLGFALYMLLSLLRIIKLKHLKRKGNKEEIDRYINKSVVGWAKFIVNGIGIKINKKGLENVPDGPCLFVGNHQG
LLDVPVIVSSLDRYVGFVAKKEMLKLKILTYWMKEMKCVFMDRQNVRAAVKTINEGVENLKNGYSMLIFPEGTRSRGENL
GEFKKGSMKLGIKAGVPIVPIAIDGTYNVLEANGKKIKAADVDLIICPPIYPNELSKEEQNNLSVTIKDVIQKELERTRN
>Mature_240_residues
MKSLIFYLGFALYMLLSLLRIIKLKHLKRKGNKEEIDRYINKSVVGWAKFIVNGIGIKINKKGLENVPDGPCLFVGNHQG
LLDVPVIVSSLDRYVGFVAKKEMLKLKILTYWMKEMKCVFMDRQNVRAAVKTINEGVENLKNGYSMLIFPEGTRSRGENL
GEFKKGSMKLGIKAGVPIVPIAIDGTYNVLEANGKKIKAADVDLIICPPIYPNELSKEEQNNLSVTIKDVIQKELERTRN

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=177, Percent_Identity=25.4237288135593, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI15100175, Length=177, Percent_Identity=25.4237288135593, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI6041665, Length=181, Percent_Identity=28.7292817679558, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1789395, Length=169, Percent_Identity=29.585798816568, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17564032, Length=196, Percent_Identity=23.9795918367347, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320151, Length=178, Percent_Identity=28.0898876404494, Blast_Score=83, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24641614, Length=179, Percent_Identity=26.8156424581006, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641612, Length=179, Percent_Identity=26.8156424581006, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281364648, Length=205, Percent_Identity=23.4146341463415, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24582856, Length=205, Percent_Identity=23.4146341463415, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24582854, Length=205, Percent_Identity=23.4146341463415, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 27071; Mature: 27071

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLIFYLGFALYMLLSLLRIIKLKHLKRKGNKEEIDRYINKSVVGWAKFIVNGIGIKIN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEE
KKGLENVPDGPCLFVGNHQGLLDVPVIVSSLDRYVGFVAKKEMLKLKILTYWMKEMKCVF
CCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MDRQNVRAAVKTINEGVENLKNGYSMLIFPEGTRSRGENLGEFKKGSMKLGIKAGVPIVP
HCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHCCCCEEEEEECCCCEEE
IAIDGTYNVLEANGKKIKAADVDLIICPPIYPNELSKEEQNNLSVTIKDVIQKELERTRN
EEECCCEEEEECCCCEEEECCCCEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSLIFYLGFALYMLLSLLRIIKLKHLKRKGNKEEIDRYINKSVVGWAKFIVNGIGIKIN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEE
KKGLENVPDGPCLFVGNHQGLLDVPVIVSSLDRYVGFVAKKEMLKLKILTYWMKEMKCVF
CCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MDRQNVRAAVKTINEGVENLKNGYSMLIFPEGTRSRGENLGEFKKGSMKLGIKAGVPIVP
HCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHCCCCEEEEEECCCCEEE
IAIDGTYNVLEANGKKIKAADVDLIICPPIYPNELSKEEQNNLSVTIKDVIQKELERTRN
EEECCCEEEEECCCCEEEECCCCEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7569993; 8253680 [H]