Click here to switch to the map view.

The map label for this gene is frc [H]

Identifier: 153934626

GI number: 153934626

Start: 2278586

End: 2279800

Strand: Reverse

Name: frc [H]

Synonym: CLC_2142

Alternate gene names: 153934626

Gene position: 2279800-2278586 (Counterclockwise)

Preceding gene: 153935150

Following gene: 153936713

Centisome position: 60.62

GC content: 32.67

Gene sequence:

>1215_bases
ATGACAAAAGAGGGTTTAGCTTTAGAAGGTGTAAAAGTAGTTGAATTATCAAGCTTTGTAGCAGCTCCTAGTTGTTCAAA
ATTATTAGCTGATTGGGGAGCTGATGTAATTAAAATAGAACCAATTCAAGGAGATAATATAAGAGTTGTAGGTGGAGTAT
ATAATTCACCAGCAAGAGATGATGAAAATCCTATGTTTGAACTTGAAAACGGAAATAAAAGAGGCATTGCAATAAATACT
AGAAGTGAAAAGGGTAAAGAAGTATTAGGAAAATTACTTAAAGATGCAGATGTTTTTGTTACAAATGTAAGAGAAAAAGC
ATTACAAAGAAGTGGATTATCCTATGACCAATTAAAGGATAAATATCCTTCATTAATACATGCACATATATTAGGATATG
GAGAAAAAGGACCACTTAAGGATAAGCCTGGATTTGACTATACTGCATATTTTGCAAGAGGAGCTGTAAGTACATCTTTA
ATGGAAAAAGGAACATCACCAGCTAATACTAATGCAGGCTTTGGTGATCATTATGCAGGCATGAGTTTAGCAGCTGGTAT
ATTAGCAGCACTTCACAGAAAGACATTAACTGGAAAGGGTGACAGAGTCACAGTAAGTCTATATCATACAGCTATATTTG
GTATGGGACTAATGATTACTACAGCTCAATACGGAAACAAAATGCCATTATCAAGAAGAACTCCTAATAATCCATTAGCA
ACAACCTATAGATGCAAAGATGATAGATGGATACAATTAGCATTACTTAAATATGATGCATGGTTCCCTAAATTCTGTAA
GGAAGTAATAAATAGACCTGATTTAATAGAAGATTCAAGATTTAATAAACAATCTGAAGTAGTAAAGCATGTTGAAACTT
TTGTTGGAATATTAGAAGGAGAATTTATTAAGAAGGATTTAAAGGAATGGGCAGATTTATTAGATAAAGCTGACTTACCA
TATGAAAAATTACAATATTGTGAAGATATATTAGAAGACGAACAAGCATGGGCAAATGACTATTTATTCAAGACCACATA
TGACAGTGGAAATACTGGTGTATTAGTTAATTCACCTGTTAAATTTAGTGAAGCTGGAATGAGACCATATAAAGCTGCAC
CAAAGATCGGTGAAGACACTGAGGTAGTTCTTACATCATTAGGATACAGTAAAGAAGAAATAGAAGAAATGAGAAAAGAA
GAGTCAATAAAATAA

Upstream 100 bases:

>100_bases
TATTATTTAGCTGAATTTGGTACAAGTTTACCTTTTGGAAGTAAGGTAAGCTTAACCATTTCAATATAGTAAAGTTTAAT
ATTTAAGGAGGAATGTTAAA

Downstream 100 bases:

>100_bases
ATTAGTGTAAGTTTTTAAATGGAGGGTATAAAAACTTAGATCAAGAAGGGGGAGGAATATAAATGGCTGATAAGAAAGAG
GTCAAAAAGAATGCAGCAAA

Product: putative hydroxyacyl-CoA:R-2-hydroxyglutaryl-CoA transferase

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTKEGLALEGVKVVELSSFVAAPSCSKLLADWGADVIKIEPIQGDNIRVVGGVYNSPARDDENPMFELENGNKRGIAINT
RSEKGKEVLGKLLKDADVFVTNVREKALQRSGLSYDQLKDKYPSLIHAHILGYGEKGPLKDKPGFDYTAYFARGAVSTSL
MEKGTSPANTNAGFGDHYAGMSLAAGILAALHRKTLTGKGDRVTVSLYHTAIFGMGLMITTAQYGNKMPLSRRTPNNPLA
TTYRCKDDRWIQLALLKYDAWFPKFCKEVINRPDLIEDSRFNKQSEVVKHVETFVGILEGEFIKKDLKEWADLLDKADLP
YEKLQYCEDILEDEQAWANDYLFKTTYDSGNTGVLVNSPVKFSEAGMRPYKAAPKIGEDTEVVLTSLGYSKEEIEEMRKE
ESIK

Sequences:

>Translated_404_residues
MTKEGLALEGVKVVELSSFVAAPSCSKLLADWGADVIKIEPIQGDNIRVVGGVYNSPARDDENPMFELENGNKRGIAINT
RSEKGKEVLGKLLKDADVFVTNVREKALQRSGLSYDQLKDKYPSLIHAHILGYGEKGPLKDKPGFDYTAYFARGAVSTSL
MEKGTSPANTNAGFGDHYAGMSLAAGILAALHRKTLTGKGDRVTVSLYHTAIFGMGLMITTAQYGNKMPLSRRTPNNPLA
TTYRCKDDRWIQLALLKYDAWFPKFCKEVINRPDLIEDSRFNKQSEVVKHVETFVGILEGEFIKKDLKEWADLLDKADLP
YEKLQYCEDILEDEQAWANDYLFKTTYDSGNTGVLVNSPVKFSEAGMRPYKAAPKIGEDTEVVLTSLGYSKEEIEEMRKE
ESIK
>Mature_403_residues
TKEGLALEGVKVVELSSFVAAPSCSKLLADWGADVIKIEPIQGDNIRVVGGVYNSPARDDENPMFELENGNKRGIAINTR
SEKGKEVLGKLLKDADVFVTNVREKALQRSGLSYDQLKDKYPSLIHAHILGYGEKGPLKDKPGFDYTAYFARGAVSTSLM
EKGTSPANTNAGFGDHYAGMSLAAGILAALHRKTLTGKGDRVTVSLYHTAIFGMGLMITTAQYGNKMPLSRRTPNNPLAT
TYRCKDDRWIQLALLKYDAWFPKFCKEVINRPDLIEDSRFNKQSEVVKHVETFVGILEGEFIKKDLKEWADLLDKADLPY
EKLQYCEDILEDEQAWANDYLFKTTYDSGNTGVLVNSPVKFSEAGMRPYKAAPKIGEDTEVVLTSLGYSKEEIEEMRKEE
SIK

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=394, Percent_Identity=25.6345177664975, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI300863124, Length=331, Percent_Identity=26.8882175226586, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI266456254, Length=410, Percent_Identity=25.3658536585366, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI300863126, Length=392, Percent_Identity=23.9795918367347, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI42794625, Length=410, Percent_Identity=25.3658536585366, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI266458393, Length=318, Percent_Identity=24.5283018867925, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI266458397, Length=275, Percent_Identity=26.5454545454545, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI1788717, Length=423, Percent_Identity=29.3144208037825, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI87082093, Length=363, Percent_Identity=24.2424242424242, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786222, Length=403, Percent_Identity=23.8213399503722, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI115535051, Length=322, Percent_Identity=25.1552795031056, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI32564160, Length=320, Percent_Identity=25, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24648431, Length=405, Percent_Identity=28.641975308642, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24585488, Length=376, Percent_Identity=27.3936170212766, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 44992; Mature: 44860

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKEGLALEGVKVVELSSFVAAPSCSKLLADWGADVIKIEPIQGDNIRVVGGVYNSPARD
CCCCCCEECCEEEEEHHHHHCCCCHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCCCCC
DENPMFELENGNKRGIAINTRSEKGKEVLGKLLKDADVFVTNVREKALQRSGLSYDQLKD
CCCCEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
KYPSLIHAHILGYGEKGPLKDKPGFDYTAYFARGAVSTSLMEKGTSPANTNAGFGDHYAG
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
MSLAAGILAALHRKTLTGKGDRVTVSLYHTAIFGMGLMITTAQYGNKMPLSRRTPNNPLA
HHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHEEEHHCCCCCCCCCCCCCCCCC
TTYRCKDDRWIQLALLKYDAWFPKFCKEVINRPDLIEDSRFNKQSEVVKHVETFVGILEG
EEEEECCCCEEEEEEEHHHCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
EFIKKDLKEWADLLDKADLPYEKLQYCEDILEDEQAWANDYLFKTTYDSGNTGVLVNSPV
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEECCCC
KFSEAGMRPYKAAPKIGEDTEVVLTSLGYSKEEIEEMRKEESIK
CHHHCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKEGLALEGVKVVELSSFVAAPSCSKLLADWGADVIKIEPIQGDNIRVVGGVYNSPARD
CCCCCEECCEEEEEHHHHHCCCCHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCCCCC
DENPMFELENGNKRGIAINTRSEKGKEVLGKLLKDADVFVTNVREKALQRSGLSYDQLKD
CCCCEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
KYPSLIHAHILGYGEKGPLKDKPGFDYTAYFARGAVSTSLMEKGTSPANTNAGFGDHYAG
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
MSLAAGILAALHRKTLTGKGDRVTVSLYHTAIFGMGLMITTAQYGNKMPLSRRTPNNPLA
HHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHEEEHHCCCCCCCCCCCCCCCCC
TTYRCKDDRWIQLALLKYDAWFPKFCKEVINRPDLIEDSRFNKQSEVVKHVETFVGILEG
EEEEECCCCEEEEEEEHHHCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
EFIKKDLKEWADLLDKADLPYEKLQYCEDILEDEQAWANDYLFKTTYDSGNTGVLVNSPV
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEECCCC
KFSEAGMRPYKAAPKIGEDTEVVLTSLGYSKEEIEEMRKEESIK
CHHHCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]