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The map label for this gene is bcd [H]

Identifier: 153934592

GI number: 153934592

Start: 2274766

End: 2275899

Strand: Reverse

Name: bcd [H]

Synonym: CLC_2139

Alternate gene names: 153934592

Gene position: 2275899-2274766 (Counterclockwise)

Preceding gene: 153937293

Following gene: 153935221

Centisome position: 60.52

GC content: 34.92

Gene sequence:

>1134_bases
ATGTTATTTAAAAAAGAGCATGAACTTTTAAGAAAGTCCGTAAGGGATTTTGTAGATAGGGAATTAAAAGATATTCCAGA
AGAAGTTGATACTGAGGGGAAACTACCTAAAGAGTTATTACAAAAACTTGCAAAATATAAATTCATAAGTCCTGTAATAC
CTAAGGAATATGGTGGAGCTGGAGCAGACTATGTATCATACTGCATAATAATGGAAGAGATCAGTAAAAGATGCGCATCT
ACTGGAACTTTTATAACAGCAGGAGCATCATTAGTAGCATTACCTTTACTTAATTTTGGAACAGAGGAACAAAAAGAAAA
ATATTTAAAACCTCTTGCTAAAGGAGAATATATTGGATCTTTTGGGCTTACAGAGCCAGGAGCAGGATCTGATGCTGGTG
CGGGACAAACTACAGCAGTTTTAGAGGGAGATTATTATATTCTAAATGGAAGAAAAACATTTATTACAAATGCACCTATT
TGTGACTTTGCTATAGTAACAGCAATGACAGAAAAGGGTAAAGGATCAAGGGGGATTTCAGCCTTTATAGTTGAAAGTAA
ATGGGATGGATTTTCAACAGGAGCTCATGAAAATAAAATGGGCATTAGAGGAACTGAGACAGCGGACTTAATATTTGAAA
ATGTAAAAGTTCCTAAAGAAAACCTTATTGGAAAAGAAGGCAAAGGATTTAAAATAGCTCTAAATACTCTTGATGTTGGT
AGAATCGGGGTAGCAGCTCAAGCTCTTGGAATAGCTCAAGGTGCTTTAGATGAAGCTATAAAGTATGTTAAGGAAAGAGT
TCAGTTTGGTAAGCCTTTAGCAAAATTCCAAAATACTCAATTTACAATTGCAGATATGGAAACAAAGGTTCAAGCTGCAA
GATGGCTTGTATATGATGCAGCAGAGAAGAAAGACAATGGCATAAATCCAGGTGTTGAATCAGCAATGGCTAAATATTAT
GCAGCGGAAATTGCAAATGAAGTAGCATATAAAGCATTACAATTACATGGCGGATATGGATTTATGAAGGATTATCCAAT
AGAAAGAATGTATAGAGATGCTAGAATTACATCTATATATGAAGGTACATCTCAAGTTCAGCAAATGGTTATTGCTGGGA
AAGCTCTTAAATAG

Upstream 100 bases:

>100_bases
ATGAAACTAAAAAAAGTATAGGGATTTATAAATACTTTAAAAAATTAAAATGAAAAATCACTACATTTTATTAAAGGTTT
AAATTTAAAAGGAGGAAAGT

Downstream 100 bases:

>100_bases
ATATATATGAGAAATAAACAAAATTGGAGGTTAAGAATTTGAGGATAGTAGTATGCGTTAAGCAAGTTCCAGATACAACA
GAAGTAAAGATAGATCCTAA

Product: acyl-CoA dehydrogenase family protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MLFKKEHELLRKSVRDFVDRELKDIPEEVDTEGKLPKELLQKLAKYKFISPVIPKEYGGAGADYVSYCIIMEEISKRCAS
TGTFITAGASLVALPLLNFGTEEQKEKYLKPLAKGEYIGSFGLTEPGAGSDAGAGQTTAVLEGDYYILNGRKTFITNAPI
CDFAIVTAMTEKGKGSRGISAFIVESKWDGFSTGAHENKMGIRGTETADLIFENVKVPKENLIGKEGKGFKIALNTLDVG
RIGVAAQALGIAQGALDEAIKYVKERVQFGKPLAKFQNTQFTIADMETKVQAARWLVYDAAEKKDNGINPGVESAMAKYY
AAEIANEVAYKALQLHGGYGFMKDYPIERMYRDARITSIYEGTSQVQQMVIAGKALK

Sequences:

>Translated_377_residues
MLFKKEHELLRKSVRDFVDRELKDIPEEVDTEGKLPKELLQKLAKYKFISPVIPKEYGGAGADYVSYCIIMEEISKRCAS
TGTFITAGASLVALPLLNFGTEEQKEKYLKPLAKGEYIGSFGLTEPGAGSDAGAGQTTAVLEGDYYILNGRKTFITNAPI
CDFAIVTAMTEKGKGSRGISAFIVESKWDGFSTGAHENKMGIRGTETADLIFENVKVPKENLIGKEGKGFKIALNTLDVG
RIGVAAQALGIAQGALDEAIKYVKERVQFGKPLAKFQNTQFTIADMETKVQAARWLVYDAAEKKDNGINPGVESAMAKYY
AAEIANEVAYKALQLHGGYGFMKDYPIERMYRDARITSIYEGTSQVQQMVIAGKALK
>Mature_377_residues
MLFKKEHELLRKSVRDFVDRELKDIPEEVDTEGKLPKELLQKLAKYKFISPVIPKEYGGAGADYVSYCIIMEEISKRCAS
TGTFITAGASLVALPLLNFGTEEQKEKYLKPLAKGEYIGSFGLTEPGAGSDAGAGQTTAVLEGDYYILNGRKTFITNAPI
CDFAIVTAMTEKGKGSRGISAFIVESKWDGFSTGAHENKMGIRGTETADLIFENVKVPKENLIGKEGKGFKIALNTLDVG
RIGVAAQALGIAQGALDEAIKYVKERVQFGKPLAKFQNTQFTIADMETKVQAARWLVYDAAEKKDNGINPGVESAMAKYY
AAEIANEVAYKALQLHGGYGFMKDYPIERMYRDARITSIYEGTSQVQQMVIAGKALK

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=375, Percent_Identity=47.7333333333333, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI4501859, Length=370, Percent_Identity=41.8918918918919, Blast_Score=295, Evalue=4e-80,
Organism=Homo sapiens, GI226958412, Length=379, Percent_Identity=38.5224274406332, Blast_Score=263, Evalue=2e-70,
Organism=Homo sapiens, GI226958414, Length=376, Percent_Identity=38.2978723404255, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI187960098, Length=373, Percent_Identity=37.8016085790885, Blast_Score=252, Evalue=3e-67,
Organism=Homo sapiens, GI4557231, Length=373, Percent_Identity=37.8016085790885, Blast_Score=252, Evalue=5e-67,
Organism=Homo sapiens, GI7656849, Length=382, Percent_Identity=37.434554973822, Blast_Score=248, Evalue=1e-65,
Organism=Homo sapiens, GI4501857, Length=374, Percent_Identity=36.096256684492, Blast_Score=245, Evalue=4e-65,
Organism=Homo sapiens, GI21361497, Length=358, Percent_Identity=38.8268156424581, Blast_Score=231, Evalue=7e-61,
Organism=Homo sapiens, GI4557235, Length=328, Percent_Identity=36.5853658536585, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI76496475, Length=328, Percent_Identity=36.5853658536585, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI4503943, Length=371, Percent_Identity=30.4582210242588, Blast_Score=168, Evalue=6e-42,
Organism=Homo sapiens, GI7669494, Length=356, Percent_Identity=30.6179775280899, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI211971008, Length=293, Percent_Identity=31.740614334471, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI48976061, Length=293, Percent_Identity=31.740614334471, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI38505218, Length=401, Percent_Identity=28.428927680798, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI218563752, Length=202, Percent_Identity=31.6831683168317, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI87081958, Length=381, Percent_Identity=30.9711286089239, Blast_Score=174, Evalue=8e-45,
Organism=Escherichia coli, GI1786223, Length=381, Percent_Identity=29.6587926509186, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI87081702, Length=367, Percent_Identity=27.5204359673025, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI87082384, Length=308, Percent_Identity=23.7012987012987, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17508101, Length=370, Percent_Identity=39.7297297297297, Blast_Score=285, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI17534899, Length=350, Percent_Identity=42.2857142857143, Blast_Score=268, Evalue=5e-72,
Organism=Caenorhabditis elegans, GI17506239, Length=368, Percent_Identity=38.5869565217391, Blast_Score=265, Evalue=4e-71,
Organism=Caenorhabditis elegans, GI17569725, Length=369, Percent_Identity=38.4823848238482, Blast_Score=255, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI17570075, Length=370, Percent_Identity=38.1081081081081, Blast_Score=253, Evalue=1e-67,
Organism=Caenorhabditis elegans, GI17533517, Length=373, Percent_Identity=38.3378016085791, Blast_Score=252, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI17538396, Length=370, Percent_Identity=35.4054054054054, Blast_Score=243, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI71990804, Length=270, Percent_Identity=44.0740740740741, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI71985184, Length=359, Percent_Identity=36.7688022284123, Blast_Score=225, Evalue=4e-59,
Organism=Caenorhabditis elegans, GI71982178, Length=275, Percent_Identity=38.9090909090909, Blast_Score=194, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI71985192, Length=294, Percent_Identity=35.7142857142857, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17534353, Length=371, Percent_Identity=32.6145552560647, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17551932, Length=374, Percent_Identity=29.9465240641711, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI32563615, Length=225, Percent_Identity=39.1111111111111, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17505929, Length=374, Percent_Identity=29.144385026738, Blast_Score=171, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI17531909, Length=237, Percent_Identity=37.1308016877637, Blast_Score=158, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17562446, Length=342, Percent_Identity=32.7485380116959, Blast_Score=138, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17531913, Length=176, Percent_Identity=34.0909090909091, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI86563381, Length=278, Percent_Identity=29.8561151079137, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI86563383, Length=278, Percent_Identity=29.8561151079137, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17540912, Length=375, Percent_Identity=23.7333333333333, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356377, Length=375, Percent_Identity=48.5333333333333, Blast_Score=358, Evalue=4e-99,
Organism=Drosophila melanogaster, GI24646207, Length=375, Percent_Identity=42.6666666666667, Blast_Score=311, Evalue=6e-85,
Organism=Drosophila melanogaster, GI24666513, Length=367, Percent_Identity=38.6920980926431, Blast_Score=278, Evalue=5e-75,
Organism=Drosophila melanogaster, GI24660351, Length=366, Percent_Identity=38.2513661202186, Blast_Score=252, Evalue=3e-67,
Organism=Drosophila melanogaster, GI21355753, Length=374, Percent_Identity=36.6310160427808, Blast_Score=245, Evalue=3e-65,
Organism=Drosophila melanogaster, GI281363737, Length=381, Percent_Identity=34.6456692913386, Blast_Score=214, Evalue=8e-56,
Organism=Drosophila melanogaster, GI19920834, Length=378, Percent_Identity=29.1005291005291, Blast_Score=161, Evalue=8e-40,
Organism=Drosophila melanogaster, GI24652780, Length=264, Percent_Identity=26.1363636363636, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 41299; Mature: 41299

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFKKEHELLRKSVRDFVDRELKDIPEEVDTEGKLPKELLQKLAKYKFISPVIPKEYGGA
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHCCCC
GADYVSYCIIMEEISKRCASTGTFITAGASLVALPLLNFGTEEQKEKYLKPLAKGEYIGS
CHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCC
FGLTEPGAGSDAGAGQTTAVLEGDYYILNGRKTFITNAPICDFAIVTAMTEKGKGSRGIS
CCCCCCCCCCCCCCCCEEEEEECCEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCCCE
AFIVESKWDGFSTGAHENKMGIRGTETADLIFENVKVPKENLIGKEGKGFKIALNTLDVG
EEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHCCCCCCCCEEEEEEEECCC
RIGVAAQALGIAQGALDEAIKYVKERVQFGKPLAKFQNTQFTIADMETKVQAARWLVYDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEEEHHHHHHHHHHHHHEEC
AEKKDNGINPGVESAMAKYYAAEIANEVAYKALQLHGGYGFMKDYPIERMYRDARITSIY
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
EGTSQVQQMVIAGKALK
HHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLFKKEHELLRKSVRDFVDRELKDIPEEVDTEGKLPKELLQKLAKYKFISPVIPKEYGGA
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHCCCC
GADYVSYCIIMEEISKRCASTGTFITAGASLVALPLLNFGTEEQKEKYLKPLAKGEYIGS
CHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCC
FGLTEPGAGSDAGAGQTTAVLEGDYYILNGRKTFITNAPICDFAIVTAMTEKGKGSRGIS
CCCCCCCCCCCCCCCCEEEEEECCEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCCCE
AFIVESKWDGFSTGAHENKMGIRGTETADLIFENVKVPKENLIGKEGKGFKIALNTLDVG
EEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHCCCCCCCCEEEEEEEECCC
RIGVAAQALGIAQGALDEAIKYVKERVQFGKPLAKFQNTQFTIADMETKVQAARWLVYDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEEEHHHHHHHHHHHHHEEC
AEKKDNGINPGVESAMAKYYAAEIANEVAYKALQLHGGYGFMKDYPIERMYRDARITSIY
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
EGTSQVQQMVIAGKALK
HHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]