Click here to switch to the map view.

The map label for this gene is hfq

Identifier: 153931793

GI number: 153931793

Start: 1841862

End: 1842119

Strand: Reverse

Name: hfq

Synonym: CLB_1732

Alternate gene names: 153931793

Gene position: 1842119-1841862 (Counterclockwise)

Preceding gene: 153933226

Following gene: 153931261

Centisome position: 47.68

GC content: 26.74

Gene sequence:

>258_bases
ATGACTAAAGTTGTTAATAATCTACAAGATATATTTTTAAATGGTGCTAGAAAAAATAGAATTCCTGTTACCATATATTT
AACAAATGGATTTCAATTAAAGGGATTTGTTAAAGGCTTTGATAACTTTACAGTAATATTAGATTCAGATGGCAAACAAA
TGATGATATACAAACATGCTATATCTACAATTAATCCAGCAAAACCCTTGCTATTTGTACAAAATCCTAACGGAGATGAT
TATAAAGATAAAGAATAG

Upstream 100 bases:

>100_bases
GTAAAAGATAAATAGAATTAAAAGGATTTTTAATTTATTTATAGAATTATATAAGAATAAGTTTCTAATTATTTGTAATT
TTTTAGGAGGGAAAGGTTAT

Downstream 100 bases:

>100_bases
GTTAATTGCCTATTCTTTTTTTATATGTTAATATATACAATGTTAGATAATAATACATACTTATTATTTTTCTTACATAT
AGAGGAGGATGGAAATAAAA

Product: RNA chaperone Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 85; Mature: 84

Protein sequence:

>85_residues
MTKVVNNLQDIFLNGARKNRIPVTIYLTNGFQLKGFVKGFDNFTVILDSDGKQMMIYKHAISTINPAKPLLFVQNPNGDD
YKDKE

Sequences:

>Translated_85_residues
MTKVVNNLQDIFLNGARKNRIPVTIYLTNGFQLKGFVKGFDNFTVILDSDGKQMMIYKHAISTINPAKPLLFVQNPNGDD
YKDKE
>Mature_84_residues
TKVVNNLQDIFLNGARKNRIPVTIYLTNGFQLKGFVKGFDNFTVILDSDGKQMMIYKHAISTINPAKPLLFVQNPNGDDY
KDKE

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family

Homologues:

Organism=Escherichia coli, GI1790614, Length=72, Percent_Identity=47.2222222222222, Blast_Score=75, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFQ_CLOB1 (A7FUK7)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001384054.1
- ProteinModelPortal:   A7FUK7
- SMR:   A7FUK7
- STRING:   A7FUK7
- GeneID:   5394931
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_1732
- eggNOG:   COG1923
- HOGENOM:   HBG645207
- OMA:   PYLNVLR
- ProtClustDB:   CLSK882950
- BioCyc:   CBOT441770:CLB_1732-MONOMER
- HAMAP:   MF_00436
- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163
- TIGRFAMs:   TIGR02383

Pfam domain/function: PF01423 LSM; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 9664; Mature: 9533

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVVNNLQDIFLNGARKNRIPVTIYLTNGFQLKGFVKGFDNFTVILDSDGKQMMIYKHA
CCHHHHHHHHHHCCCCCCCCCCEEEEEECCEEEEEEECCCCCEEEEEECCCCEEEEEEEC
ISTINPAKPLLFVQNPNGDDYKDKE
CCCCCCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
TKVVNNLQDIFLNGARKNRIPVTIYLTNGFQLKGFVKGFDNFTVILDSDGKQMMIYKHA
CHHHHHHHHHHCCCCCCCCCCEEEEEECCEEEEEEECCCCCEEEEEECCCCEEEEEEEC
ISTINPAKPLLFVQNPNGDDYKDKE
CCCCCCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA