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The map label for this gene is pucD [H]

Identifier: 153931042

GI number: 153931042

Start: 2996596

End: 2999151

Strand: Reverse

Name: pucD [H]

Synonym: CLB_2845

Alternate gene names: 153931042

Gene position: 2999151-2996596 (Counterclockwise)

Preceding gene: 153930943

Following gene: 153932727

Centisome position: 77.63

GC content: 34.43

Gene sequence:

>2556_bases
GTGTATGAATTTATATTAAATGAAAGAAATGTATCTGTTTCAGAGGATATTAATTTACTTGAATATTTGAGGGATAATGA
GGATTTAACTTCAGTAAAAAATGGGTGTGCAGAAGGAGCCTGTGGAGCCTGTATGATACTTGTTAATGGTAAGGCGCTTA
GAGCCTGTATATGTACAACTGCAAAGGTGAATGGAAAAGATGTTAAGACTGTAGAGGGGTTAACAGAATTTGAAAAGGAT
GTTTTTACTTGGGCTTTTTCTAAAGCTGGAGCAGTACAGTGTGGATATTGTATTCCAGGGATGATAATAAGTGCAAAGGC
ACTTTTAGATAAAAATCTAAATCCAAATAAGAAAGAAATTAAAACTGCTATTAGAGGAAATGTATGTAGATGTACTGGAT
ATGTGAAAATAATAAAAGCCATTGAAATGGCAGCAGGGGCATTTAGAAATGGTAAACTTCCATTTGCGAAAGAATATAAA
GGGAAAATAGGTGAAAATATTCCAAGAATAGATGCAAAAGATAAAATTTTAGGTATAGGAAAATATGTAGATGACATGAA
GATAGAAGGAATGGTTTATGGTTCTGCTTTAAGATCAAAATATCCTAGAGCTTTAGTAAAAAGCATTGATATAAGTGTAG
CTTTAAAACATCCAGAAGTTGAAGCTATTCTTACAGCAGAAGATGTCCCAGGAAATAGGCTTATAGGACATATTGTAAAG
GATTGGCCAGCAATGATAGCCGTAGGAGAAGGAACAAGGTATGTTGGTGATGCAGTGGCTTTAGTGGCAGCAAAAAGCAA
GAAGGCTTTAAAAGAAATACTTAATTTAATAAAGGTAGAATATGAAGAATTAGAACCTATTTCTAATCCTAATATTGCAA
TAGCTGAAGATGCTCCTAAAATTCATCCTAAGGGAAATATTTTAACAGTGGAAAAAGTTAATAGAGGAGATGTAGATGAG
GCAATAGCCAATTCTAAGTATGTGGTTACTAATCATTATTCTACTCCCTTTACTGAACATGCTTTTTTAGAGCCTGAAAG
TGCTTTAGCTATGCCAGATGGGGATGGAGTTATTATTTATACAGGAAGCCAAGGTATATATGATGAGCAGAGAGAGATTT
CTGAGCTTTTAGGGCTTCCTAAAGAAAAAGTAAGGACTATTAGCAAATATGTGGGTGGAGGCTTTGGTGGAAAAGAAGAT
ATGAGTGTACAACATCATGCCGCTCTTCTTGCATGGACTATTAAAAAGCCCGTTAAAATAACTTTAAGTCGTAAGGAAAG
TATAAAGATTCATCCTAAAAGACATGCTATGGAAATGACAATTACTACTGCATGTGATGAAAAAGGAAATTTAACTGCTT
TTAAAGCAGATATTATATCAGATACTGGTGCCTATGCATCATTAGGAGGACCTGTACTCCAAAGAGCTTGTACTCATGCA
GCTGGCCCATATAAATGTCCTAATGTGAAAATAAAAGGTACCGCTGTATATACTAACAATCCCCCAGGAGGAGCTTTTAG
GGGATTTGGAGTAACACAATCAGTTTTTGGATCAGAGTGCAACTTAAATCTTTTAGCTGAAAAAGTTGGTATATCTCCTT
GGGAAATAAGATTTAAAAACGCAGTAGAACCTGGAGATGCACTACCTAATGGACAAATTGCTGATAAAGGAACTGCAATT
AAAGAAACTATATTAGCTGTGAAAGATGTATATAAAAAGAGTAAATGTGCAGGAATAGCCTGTTGTATGAAAAATTCAGG
AGTTGGTGTTGGAATACCGGATATTGGAAGATGTAACTTAATAGTAATAGATGGAAAGGTTCATATAAGAACTAGTGCAG
CTTGCATAGGTCAAGGTCTTGGAACAATTCTTACACAAATAATATGTGAAACAATAGGTTTATTACCAGAACAGATAATT
TTAGATTTACCAGATACAAAATTTGCACCAGATTCAGGGACAACTACAGCATCAAGACAAACAGTATTTACTGGAGAAGC
CACAAGAATGGCATCATTAAAGCTTAAGGAAAAATTATTAACTACATCATTAGAAGAGTGTGAAGGTGAAGAATTTTATG
GGGAATATCAAAGTATTACAGATCCTATTAATTCTGATAAAAAGAATCCAGTAAGTCACGTGGCTTATGGCTATGCAACA
CAAGTTGTTATTCTTGATGATGATGGAAAAGTAGAAAGAGTAGTTGCAGCACATGATGTGGGAAAAGCTATAAATTTAAC
TAATGTAGAAGGACAAATTGAAGGTGGAATAGTTATGGGACTTGGGTATGCATTTACAGAAGATTATCCATTAAATAAAT
CTATCCCAACTGCTAAGTTTGGCACATTAGGTTTGTTTAGAGCTACTGATATACCAGAAATTGAAACAACAATAATTGAA
AAGAATACTAATGATTTAGCTTATGGTGCAAAAGGAATAGGAGAAATTACAACCATACCAACAGCCCCAGCAGCTCAAGG
TGCTTACTATAAATTTGATGGAAACTTTAGAAAAAAGCTTCCACTTGAGGATACTGCTTATAGAAGAAAAAAATAA

Upstream 100 bases:

>100_bases
AGTAGTCATCGTATAAAGTTCATTTATAGTTTTATACATTTAGACATATAAAGAGAAAATAATAGGCTTATTGATACATA
AATATATGGGGGTAATAAAT

Downstream 100 bases:

>100_bases
TTATCTTAGATAGTAATATTTTAAAATAGATTTAATTTTAACCATGCAAATATAAAAAATACATGTATAGATAGATAACT
TACTTGACTAGGAATCTCAA

Product: xanthine dehydrogenase family protein, molybdopterin-binding subunit

Products: NA

Alternate protein names: XDHase subunit D [H]

Number of amino acids: Translated: 851; Mature: 851

Protein sequence:

>851_residues
MYEFILNERNVSVSEDINLLEYLRDNEDLTSVKNGCAEGACGACMILVNGKALRACICTTAKVNGKDVKTVEGLTEFEKD
VFTWAFSKAGAVQCGYCIPGMIISAKALLDKNLNPNKKEIKTAIRGNVCRCTGYVKIIKAIEMAAGAFRNGKLPFAKEYK
GKIGENIPRIDAKDKILGIGKYVDDMKIEGMVYGSALRSKYPRALVKSIDISVALKHPEVEAILTAEDVPGNRLIGHIVK
DWPAMIAVGEGTRYVGDAVALVAAKSKKALKEILNLIKVEYEELEPISNPNIAIAEDAPKIHPKGNILTVEKVNRGDVDE
AIANSKYVVTNHYSTPFTEHAFLEPESALAMPDGDGVIIYTGSQGIYDEQREISELLGLPKEKVRTISKYVGGGFGGKED
MSVQHHAALLAWTIKKPVKITLSRKESIKIHPKRHAMEMTITTACDEKGNLTAFKADIISDTGAYASLGGPVLQRACTHA
AGPYKCPNVKIKGTAVYTNNPPGGAFRGFGVTQSVFGSECNLNLLAEKVGISPWEIRFKNAVEPGDALPNGQIADKGTAI
KETILAVKDVYKKSKCAGIACCMKNSGVGVGIPDIGRCNLIVIDGKVHIRTSAACIGQGLGTILTQIICETIGLLPEQII
LDLPDTKFAPDSGTTTASRQTVFTGEATRMASLKLKEKLLTTSLEECEGEEFYGEYQSITDPINSDKKNPVSHVAYGYAT
QVVILDDDGKVERVVAAHDVGKAINLTNVEGQIEGGIVMGLGYAFTEDYPLNKSIPTAKFGTLGLFRATDIPEIETTIIE
KNTNDLAYGAKGIGEITTIPTAPAAQGAYYKFDGNFRKKLPLEDTAYRRKK

Sequences:

>Translated_851_residues
MYEFILNERNVSVSEDINLLEYLRDNEDLTSVKNGCAEGACGACMILVNGKALRACICTTAKVNGKDVKTVEGLTEFEKD
VFTWAFSKAGAVQCGYCIPGMIISAKALLDKNLNPNKKEIKTAIRGNVCRCTGYVKIIKAIEMAAGAFRNGKLPFAKEYK
GKIGENIPRIDAKDKILGIGKYVDDMKIEGMVYGSALRSKYPRALVKSIDISVALKHPEVEAILTAEDVPGNRLIGHIVK
DWPAMIAVGEGTRYVGDAVALVAAKSKKALKEILNLIKVEYEELEPISNPNIAIAEDAPKIHPKGNILTVEKVNRGDVDE
AIANSKYVVTNHYSTPFTEHAFLEPESALAMPDGDGVIIYTGSQGIYDEQREISELLGLPKEKVRTISKYVGGGFGGKED
MSVQHHAALLAWTIKKPVKITLSRKESIKIHPKRHAMEMTITTACDEKGNLTAFKADIISDTGAYASLGGPVLQRACTHA
AGPYKCPNVKIKGTAVYTNNPPGGAFRGFGVTQSVFGSECNLNLLAEKVGISPWEIRFKNAVEPGDALPNGQIADKGTAI
KETILAVKDVYKKSKCAGIACCMKNSGVGVGIPDIGRCNLIVIDGKVHIRTSAACIGQGLGTILTQIICETIGLLPEQII
LDLPDTKFAPDSGTTTASRQTVFTGEATRMASLKLKEKLLTTSLEECEGEEFYGEYQSITDPINSDKKNPVSHVAYGYAT
QVVILDDDGKVERVVAAHDVGKAINLTNVEGQIEGGIVMGLGYAFTEDYPLNKSIPTAKFGTLGLFRATDIPEIETTIIE
KNTNDLAYGAKGIGEITTIPTAPAAQGAYYKFDGNFRKKLPLEDTAYRRKK
>Mature_851_residues
MYEFILNERNVSVSEDINLLEYLRDNEDLTSVKNGCAEGACGACMILVNGKALRACICTTAKVNGKDVKTVEGLTEFEKD
VFTWAFSKAGAVQCGYCIPGMIISAKALLDKNLNPNKKEIKTAIRGNVCRCTGYVKIIKAIEMAAGAFRNGKLPFAKEYK
GKIGENIPRIDAKDKILGIGKYVDDMKIEGMVYGSALRSKYPRALVKSIDISVALKHPEVEAILTAEDVPGNRLIGHIVK
DWPAMIAVGEGTRYVGDAVALVAAKSKKALKEILNLIKVEYEELEPISNPNIAIAEDAPKIHPKGNILTVEKVNRGDVDE
AIANSKYVVTNHYSTPFTEHAFLEPESALAMPDGDGVIIYTGSQGIYDEQREISELLGLPKEKVRTISKYVGGGFGGKED
MSVQHHAALLAWTIKKPVKITLSRKESIKIHPKRHAMEMTITTACDEKGNLTAFKADIISDTGAYASLGGPVLQRACTHA
AGPYKCPNVKIKGTAVYTNNPPGGAFRGFGVTQSVFGSECNLNLLAEKVGISPWEIRFKNAVEPGDALPNGQIADKGTAI
KETILAVKDVYKKSKCAGIACCMKNSGVGVGIPDIGRCNLIVIDGKVHIRTSAACIGQGLGTILTQIICETIGLLPEQII
LDLPDTKFAPDSGTTTASRQTVFTGEATRMASLKLKEKLLTTSLEECEGEEFYGEYQSITDPINSDKKNPVSHVAYGYAT
QVVILDDDGKVERVVAAHDVGKAINLTNVEGQIEGGIVMGLGYAFTEDYPLNKSIPTAKFGTLGLFRATDIPEIETTIIE
KNTNDLAYGAKGIGEITTIPTAPAAQGAYYKFDGNFRKKLPLEDTAYRRKK

Specific function: Oxidizes hypoxanthine and xanthine to uric acid [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=711, Percent_Identity=26.5822784810127, Blast_Score=192, Evalue=1e-48,
Organism=Homo sapiens, GI71773480, Length=712, Percent_Identity=25.4213483146067, Blast_Score=149, Evalue=1e-35,
Organism=Escherichia coli, GI1789230, Length=736, Percent_Identity=29.6195652173913, Blast_Score=290, Evalue=4e-79,
Organism=Escherichia coli, GI1789246, Length=948, Percent_Identity=26.0548523206751, Blast_Score=253, Evalue=4e-68,
Organism=Escherichia coli, GI1786478, Length=732, Percent_Identity=24.0437158469945, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1789232, Length=129, Percent_Identity=42.6356589147287, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1786480, Length=157, Percent_Identity=35.031847133758, Blast_Score=96, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17540638, Length=716, Percent_Identity=25.5586592178771, Blast_Score=172, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI32566215, Length=715, Percent_Identity=23.9160839160839, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17539860, Length=735, Percent_Identity=22.9931972789116, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17737937, Length=686, Percent_Identity=27.2594752186589, Blast_Score=173, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24647193, Length=691, Percent_Identity=23.8784370477569, Blast_Score=120, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24647199, Length=645, Percent_Identity=22.7906976744186, Blast_Score=105, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24647201, Length=657, Percent_Identity=23.1354642313546, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24647197, Length=148, Percent_Identity=29.0540540540541, Blast_Score=73, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24647195, Length=148, Percent_Identity=29.0540540540541, Blast_Score=73, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR017609 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 91931; Mature: 91931

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYEFILNERNVSVSEDINLLEYLRDNEDLTSVKNGCAEGACGACMILVNGKALRACICTT
CCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCEEEEEECCCEEEEEEEEC
AKVNGKDVKTVEGLTEFEKDVFTWAFSKAGAVQCGYCIPGMIISAKALLDKNLNPNKKEI
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHCCCCCCCHHHH
KTAIRGNVCRCTGYVKIIKAIEMAAGAFRNGKLPFAKEYKGKIGENIPRIDAKDKILGIG
HHHHCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCHHCCCCCCCCCCCCEEECC
KYVDDMKIEGMVYGSALRSKYPRALVKSIDISVALKHPEVEAILTAEDVPGNRLIGHIVK
CCCCCEEECEEEECHHHHHHHHHHHHHHCCEEEEEECCCEEEEEEECCCCCCHHHHHHHH
DWPAMIAVGEGTRYVGDAVALVAAKSKKALKEILNLIKVEYEELEPISNPNIAIAEDAPK
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCC
IHPKGNILTVEKVNRGDVDEAIANSKYVVTNHYSTPFTEHAFLEPESALAMPDGDGVIIY
CCCCCCEEEEEECCCCCHHHHHCCCCEEEEECCCCCCCCCEEECCCCCEECCCCCEEEEE
TGSQGIYDEQREISELLGLPKEKVRTISKYVGGGFGGKEDMSVQHHAALLAWTIKKPVKI
ECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHEEEEEEECCCEEE
TLSRKESIKIHPKRHAMEMTITTACDEKGNLTAFKADIISDTGAYASLGGPVLQRACTHA
EEECCCCEEECCCCCEEEEEEEEECCCCCCEEEEEEEHHCCCCCCHHCCHHHHHHHHHHC
AGPYKCPNVKIKGTAVYTNNPPGGAFRGFGVTQSVFGSECNLNLLAEKVGISPWEIRFKN
CCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCHHHCCCCCCCEEHHHHHCCCCEEEEECC
AVEPGDALPNGQIADKGTAIKETILAVKDVYKKSKCAGIACCMKNSGVGVGIPDIGRCNL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEECCCCCCCEEE
IVIDGKVHIRTSAACIGQGLGTILTQIICETIGLLPEQIILDLPDTKFAPDSGTTTASRQ
EEECCEEEEEEHHHHHHCCHHHHHHHHHHHHHCCCCHHHEEECCCCCCCCCCCCCCCCCC
TVFTGEATRMASLKLKEKLLTTSLEECEGEEFYGEYQSITDPINSDKKNPVSHVAYGYAT
EEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHEEECEEE
QVVILDDDGKVERVVAAHDVGKAINLTNVEGQIEGGIVMGLGYAFTEDYPLNKSIPTAKF
EEEEECCCCCEEEEEEHHHCCCEEEEECCCCEECCCEEEEECEEECCCCCCCCCCCCCCC
GTLGLFRATDIPEIETTIIEKNTNDLAYGAKGIGEITTIPTAPAAQGAYYKFDGNFRKKL
CCEEEEECCCCCCCEEEEEECCCCCHHCCCCCCCCEEECCCCCCCCCCEEEECCCCCCCC
PLEDTAYRRKK
CCCCCHHHCCC
>Mature Secondary Structure
MYEFILNERNVSVSEDINLLEYLRDNEDLTSVKNGCAEGACGACMILVNGKALRACICTT
CCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCEEEEEECCCEEEEEEEEC
AKVNGKDVKTVEGLTEFEKDVFTWAFSKAGAVQCGYCIPGMIISAKALLDKNLNPNKKEI
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHCCCCCCCHHHH
KTAIRGNVCRCTGYVKIIKAIEMAAGAFRNGKLPFAKEYKGKIGENIPRIDAKDKILGIG
HHHHCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCHHCCCCCCCCCCCCEEECC
KYVDDMKIEGMVYGSALRSKYPRALVKSIDISVALKHPEVEAILTAEDVPGNRLIGHIVK
CCCCCEEECEEEECHHHHHHHHHHHHHHCCEEEEEECCCEEEEEEECCCCCCHHHHHHHH
DWPAMIAVGEGTRYVGDAVALVAAKSKKALKEILNLIKVEYEELEPISNPNIAIAEDAPK
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCC
IHPKGNILTVEKVNRGDVDEAIANSKYVVTNHYSTPFTEHAFLEPESALAMPDGDGVIIY
CCCCCCEEEEEECCCCCHHHHHCCCCEEEEECCCCCCCCCEEECCCCCEECCCCCEEEEE
TGSQGIYDEQREISELLGLPKEKVRTISKYVGGGFGGKEDMSVQHHAALLAWTIKKPVKI
ECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHEEEEEEECCCEEE
TLSRKESIKIHPKRHAMEMTITTACDEKGNLTAFKADIISDTGAYASLGGPVLQRACTHA
EEECCCCEEECCCCCEEEEEEEEECCCCCCEEEEEEEHHCCCCCCHHCCHHHHHHHHHHC
AGPYKCPNVKIKGTAVYTNNPPGGAFRGFGVTQSVFGSECNLNLLAEKVGISPWEIRFKN
CCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCHHHCCCCCCCEEHHHHHCCCCEEEEECC
AVEPGDALPNGQIADKGTAIKETILAVKDVYKKSKCAGIACCMKNSGVGVGIPDIGRCNL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEECCCCCCCEEE
IVIDGKVHIRTSAACIGQGLGTILTQIICETIGLLPEQIILDLPDTKFAPDSGTTTASRQ
EEECCEEEEEEHHHHHHCCHHHHHHHHHHHHHCCCCHHHEEECCCCCCCCCCCCCCCCCC
TVFTGEATRMASLKLKEKLLTTSLEECEGEEFYGEYQSITDPINSDKKNPVSHVAYGYAT
EEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHEEECEEE
QVVILDDDGKVERVVAAHDVGKAINLTNVEGQIEGGIVMGLGYAFTEDYPLNKSIPTAKF
EEEEECCCCCEEEEEEHHHCCCEEEEECCCCEECCCEEEEECEEECCCCCCCCCCCCCCC
GTLGLFRATDIPEIETTIIEKNTNDLAYGAKGIGEITTIPTAPAAQGAYYKFDGNFRKKL
CCEEEEECCCCCCCEEEEEECCCCCHHCCCCCCCCEEECCCCCCCCCCEEEECCCCCCCC
PLEDTAYRRKK
CCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11344136 [H]