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The map label for this gene is tcpE [H]

Identifier: 153930581

GI number: 153930581

Start: 23436

End: 24500

Strand: Direct

Name: tcpE [H]

Synonym: YpsIP31758_A0064

Alternate gene names: 153930581

Gene position: 23436-24500 (Clockwise)

Preceding gene: 153930625

Following gene: 153930579

Centisome position: 39.94

GC content: 36.62

Gene sequence:

>1065_bases
ATGAATAAGTTTAATCGTGCTCTTTATAAAATGACGTTCAATGTTAATGACCGAGAGGATGTTTATGACAATTTCAGACA
ATATCTTATAGATGGTCAGTCTGTTGATAATACATTCAAGAATTTGATTGTTAATTATACCCGGCGAGGGAGAAAACCCA
ATAGCCCGATGGCTGAGATTATAAGGGAATGGGAAGAGAAATTTAAGTTGGGCGATACATTAGGTGAGTCTTTGAGAGAA
TGGATACCCGAACAGGAGCTAAGTGTCATAGATGCTTGTGATACTGCTGGACGGCCTTGGGATGGTTTTCAAAAAGCAAT
CAAGATAGCAAGATCTGCGGAAAGAATTAAAAAAACTATCAAGGGTGCCTTTTTTACCAGCATCTACATGTTTTTACTTT
CTTTTATTTTACTGGCTTTTGCTTGCTCACTCCTTGTCCCTACATTGCTCGAAGCCGTGCCTTTATTTAGATGGAGTACC
ACACAGAAATTTGTTTATTATTTTTATATATTTATCAGTGGTTATTGGTGGGCATTAATTGCCGTTTGTTTGATAGTTGG
ATATATTATTTATCATTCATTAGACAGATGGACAGGCAACTCACGATTTCATGCTGATAAGTTTGTTCCGTATTCTCTAT
ATAAAGAAATGCATGGCGCAACATTTATTATCAATGTAGACGCGATGTTGTCAGCGGGAATACCACTAAAAGATTCACTG
ATTAAAATACGGAACATGTCTGATTCTGATTGGTTGATAGAAAGGGTGAATGGTGCAATATCAGGTTTAACTGAGGGGGA
AGAAAATTTAGGGCTAGCATTAGATATTTCTAACTTTGAATTTCCAAGTGAAGACGCAATTATTAAAATGCAGAGCCTTT
TTGAAACCGCGAATAAAGAAGGTTCATTAGAGCGTTTTGGTGAACGTCAACTTGAAAATACAATATCGAGAGTCGAAAGA
AAAACAGCAGTCATTAAAGTTGCAAGTATGGTTTTTGGTGCCGGTTGCACCGTAGGAATCTTCTTTGTCATGTACAGTTT
AATTCAACAAGTCTTTGGCATTTAA

Upstream 100 bases:

>100_bases
CCTGTTTTAAGTCATAAAGACGTTTGTAATTTGGATCGCGATTATCTCATCTTTACTGATGAAGTGAGAGCCGCAGCCAA
AGTGAATAGAGAGAAGATAA

Downstream 100 bases:

>100_bases
ATAGGAATATAAATAGATGAAAATTTTAAAGAAAGGTCTTAACGCTATTACTGATGAAACGATTGCTAAAGTCGTTGGCT
TTCTATTCCTGGCAGGTGTG

Product: putative type IV secretion system protein PilR

Products: NA

Alternate protein names: TCP pilus biosynthesis protein tcpE [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MNKFNRALYKMTFNVNDREDVYDNFRQYLIDGQSVDNTFKNLIVNYTRRGRKPNSPMAEIIREWEEKFKLGDTLGESLRE
WIPEQELSVIDACDTAGRPWDGFQKAIKIARSAERIKKTIKGAFFTSIYMFLLSFILLAFACSLLVPTLLEAVPLFRWST
TQKFVYYFYIFISGYWWALIAVCLIVGYIIYHSLDRWTGNSRFHADKFVPYSLYKEMHGATFIINVDAMLSAGIPLKDSL
IKIRNMSDSDWLIERVNGAISGLTEGEENLGLALDISNFEFPSEDAIIKMQSLFETANKEGSLERFGERQLENTISRVER
KTAVIKVASMVFGAGCTVGIFFVMYSLIQQVFGI

Sequences:

>Translated_354_residues
MNKFNRALYKMTFNVNDREDVYDNFRQYLIDGQSVDNTFKNLIVNYTRRGRKPNSPMAEIIREWEEKFKLGDTLGESLRE
WIPEQELSVIDACDTAGRPWDGFQKAIKIARSAERIKKTIKGAFFTSIYMFLLSFILLAFACSLLVPTLLEAVPLFRWST
TQKFVYYFYIFISGYWWALIAVCLIVGYIIYHSLDRWTGNSRFHADKFVPYSLYKEMHGATFIINVDAMLSAGIPLKDSL
IKIRNMSDSDWLIERVNGAISGLTEGEENLGLALDISNFEFPSEDAIIKMQSLFETANKEGSLERFGERQLENTISRVER
KTAVIKVASMVFGAGCTVGIFFVMYSLIQQVFGI
>Mature_354_residues
MNKFNRALYKMTFNVNDREDVYDNFRQYLIDGQSVDNTFKNLIVNYTRRGRKPNSPMAEIIREWEEKFKLGDTLGESLRE
WIPEQELSVIDACDTAGRPWDGFQKAIKIARSAERIKKTIKGAFFTSIYMFLLSFILLAFACSLLVPTLLEAVPLFRWST
TQKFVYYFYIFISGYWWALIAVCLIVGYIIYHSLDRWTGNSRFHADKFVPYSLYKEMHGATFIINVDAMLSAGIPLKDSL
IKIRNMSDSDWLIERVNGAISGLTEGEENLGLALDISNFEFPSEDAIIKMQSLFETANKEGSLERFGERQLENTISRVER
KTAVIKVASMVFGAGCTVGIFFVMYSLIQQVFGI

Specific function: Probably involved in cholera toxin receptor (GM1) interaction in order to bring the cells within close proximity of the ganglioside for efficient toxin delivery [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 40659; Mature: 40659

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKFNRALYKMTFNVNDREDVYDNFRQYLIDGQSVDNTFKNLIVNYTRRGRKPNSPMAEI
CCCHHHHHHHEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHH
IREWEEKFKLGDTLGESLREWIPEQELSVIDACDTAGRPWDGFQKAIKIARSAERIKKTI
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
KGAFFTSIYMFLLSFILLAFACSLLVPTLLEAVPLFRWSTTQKFVYYFYIFISGYWWALI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
AVCLIVGYIIYHSLDRWTGNSRFHADKFVPYSLYKEMHGATFIINVDAMLSAGIPLKDSL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEHHHHHCCCCCHHHH
IKIRNMSDSDWLIERVNGAISGLTEGEENLGLALDISNFEFPSEDAIIKMQSLFETANKE
HHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCC
GSLERFGERQLENTISRVERKTAVIKVASMVFGAGCTVGIFFVMYSLIQQVFGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKFNRALYKMTFNVNDREDVYDNFRQYLIDGQSVDNTFKNLIVNYTRRGRKPNSPMAEI
CCCHHHHHHHEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHH
IREWEEKFKLGDTLGESLREWIPEQELSVIDACDTAGRPWDGFQKAIKIARSAERIKKTI
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
KGAFFTSIYMFLLSFILLAFACSLLVPTLLEAVPLFRWSTTQKFVYYFYIFISGYWWALI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
AVCLIVGYIIYHSLDRWTGNSRFHADKFVPYSLYKEMHGATFIINVDAMLSAGIPLKDSL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEHHHHHCCCCCHHHH
IKIRNMSDSDWLIERVNGAISGLTEGEENLGLALDISNFEFPSEDAIIKMQSLFETANKE
HHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCC
GSLERFGERQLENTISRVERKTAVIKVASMVFGAGCTVGIFFVMYSLIQQVFGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11179381 [H]