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The map label for this gene is atoS [H]

Identifier: 153002988

GI number: 153002988

Start: 136726

End: 138219

Strand: Reverse

Name: atoS [H]

Synonym: Anae109_0111

Alternate gene names: 153002988

Gene position: 138219-136726 (Counterclockwise)

Preceding gene: 153002989

Following gene: 153002987

Centisome position: 2.62

GC content: 76.1

Gene sequence:

>1494_bases
GTGACCCTCCGGCTCAAGCTCTTCGTGCTCATCGCGGGGGTGATCATCTTCGCGATGAGCGGCGTCACCGCCGTGGCGCT
CTGGCGCGAGGTGGTGCGCGGGCAGGAGCTCCTGGCGCGCGAGGGCGTCGCCATCGCCTCCACCGCCGCCACCGCCGCCG
CCCACTGGGTCCGCGCCGACGGCGTGGACCCGGGCGGCGCCTCCGCGCTGCCGGCGGTGCTCGAGCGCGTGGTCGCGAGC
GCGCCGCTCGACCGCGCCTGGATCGTCGACCGGACCGGCAAGGTCCTCGCCTGCGTCACGCGCACCGAGGAGGCCTGCCC
CGAGGGCGCCCCGCCCTCGGAGTTCCAGCTCGCCGAGTCCCCGCTCCAGGCGCTCGGGCGGCTGCTCCAGCCGGAGGGCA
TCGTGGCCTCCGCTCCCATCCTGCGCAGCGGCGCCGTGGTGGGGGCCGTCCGGGTGGACTTCACGCACGAGGAGGTGGTG
GGGAACGCCCGCAACCTGGCGTGGGGGGCGAGCATCGTCGCCGCCTTCTGGATCTTCGTCGGGCAGCTCCTCGCCGCCAT
CTTCCTGCGCCGCGTGACGAGCCCGCTCGTGCGGCTCTCCGAGGCCGCCGAGTCGCTCGCGGAGGAGCGCGGCGTCCGCC
TCGAGGAGCCCGAGGAGCGCGAGCTCGCCGATCTGGTGCGCGCCTTCAACGACATGTCGCGGCGGCTCGACGACCGGCGC
AGCGAGAACCAGCGGCTCATCGCCGAGCTGGAGGCGCGCGTCGCGCAGAAGACCCGCGAGGTGCTGCGCGCGGACCGCCT
CGCCACGCTGGGCGGCATCGCCGCCGGCTTCGCCCACGAGATCGGCAACTCCCTGAACGTCATCCGCGGCTACGCCTCGG
TGGCGGCGCGCGAGCTGCCCGCCGACGCCGAGGTGAAGTCCGACGTGGAGGCGATCCGGCGCGAGGTCACCCGCGCGGCC
GGGCTGATCGAGCGGTTCCTGGTCTTCGCGCGCGCGCGCACGGTGCACCCCATCGCGCAGCCCGTCGAGCCGATCCTGCG
CGAGGCGGTGGAGGTGGTCGGGCCGGCCGCGGCGCACGCGAACGTCGAGCGCGTGGTCGAGATCGCGCCCGCGCTGCCGG
AGGTGGTGGCCGACGGCGAGCTGCTCCGCCAGGCCTTCCTGAACCTCTGCGTCAACGCCGTGCAGGCGATGCAGGAGCGC
GGGGGCGGGACGCTCGTCGCGCGCGCGCGCCGCGAGGGAGACGGGCTCGTGGTGGAGGTGTCGGACAGCGGCCCGGGCCT
GCCGAGGGACATCGCCGCCCACGTCTTCGACCCGTTCTTCACCACCAAGGCGAACGGCACCGGCCTCGGGCTGGCCATCG
TGCGCCAGGCGGCGGAGGCCCACGGCGGCACGGTGGAGGTCGAGAGCGCCCCCGGCCACGGCGCCACCTTCCGCATCCGC
CTGCCCGTCGCGCCGGCCGAGCCGGCCGCGGCGGGCGCAGGCGCCGCGCCGTGA

Upstream 100 bases:

>100_bases
GCCACGCGCATGCCCAGAGCCACGCGCACGGCAAGTCGTGCACCGCCTGCCACGAGTTCGGCGGGGCGCCGCGGCCGCCG
CCGCGCGGGGAGTCGTCGCC

Downstream 100 bases:

>100_bases
GCCCATCACCCGGCGCGCGATCTCGTTAGAGGACTCCCGTGACGAAGCCCAACCTGATGGTCATCGACGACCTCGACTCC
GCGCGGCAGATGATGAAGCG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 496

Protein sequence:

>497_residues
MTLRLKLFVLIAGVIIFAMSGVTAVALWREVVRGQELLAREGVAIASTAATAAAHWVRADGVDPGGASALPAVLERVVAS
APLDRAWIVDRTGKVLACVTRTEEACPEGAPPSEFQLAESPLQALGRLLQPEGIVASAPILRSGAVVGAVRVDFTHEEVV
GNARNLAWGASIVAAFWIFVGQLLAAIFLRRVTSPLVRLSEAAESLAEERGVRLEEPEERELADLVRAFNDMSRRLDDRR
SENQRLIAELEARVAQKTREVLRADRLATLGGIAAGFAHEIGNSLNVIRGYASVAARELPADAEVKSDVEAIRREVTRAA
GLIERFLVFARARTVHPIAQPVEPILREAVEVVGPAAAHANVERVVEIAPALPEVVADGELLRQAFLNLCVNAVQAMQER
GGGTLVARARREGDGLVVEVSDSGPGLPRDIAAHVFDPFFTTKANGTGLGLAIVRQAAEAHGGTVEVESAPGHGATFRIR
LPVAPAEPAAAGAGAAP

Sequences:

>Translated_497_residues
MTLRLKLFVLIAGVIIFAMSGVTAVALWREVVRGQELLAREGVAIASTAATAAAHWVRADGVDPGGASALPAVLERVVAS
APLDRAWIVDRTGKVLACVTRTEEACPEGAPPSEFQLAESPLQALGRLLQPEGIVASAPILRSGAVVGAVRVDFTHEEVV
GNARNLAWGASIVAAFWIFVGQLLAAIFLRRVTSPLVRLSEAAESLAEERGVRLEEPEERELADLVRAFNDMSRRLDDRR
SENQRLIAELEARVAQKTREVLRADRLATLGGIAAGFAHEIGNSLNVIRGYASVAARELPADAEVKSDVEAIRREVTRAA
GLIERFLVFARARTVHPIAQPVEPILREAVEVVGPAAAHANVERVVEIAPALPEVVADGELLRQAFLNLCVNAVQAMQER
GGGTLVARARREGDGLVVEVSDSGPGLPRDIAAHVFDPFFTTKANGTGLGLAIVRQAAEAHGGTVEVESAPGHGATFRIR
LPVAPAEPAAAGAGAAP
>Mature_496_residues
TLRLKLFVLIAGVIIFAMSGVTAVALWREVVRGQELLAREGVAIASTAATAAAHWVRADGVDPGGASALPAVLERVVASA
PLDRAWIVDRTGKVLACVTRTEEACPEGAPPSEFQLAESPLQALGRLLQPEGIVASAPILRSGAVVGAVRVDFTHEEVVG
NARNLAWGASIVAAFWIFVGQLLAAIFLRRVTSPLVRLSEAAESLAEERGVRLEEPEERELADLVRAFNDMSRRLDDRRS
ENQRLIAELEARVAQKTREVLRADRLATLGGIAAGFAHEIGNSLNVIRGYASVAARELPADAEVKSDVEAIRREVTRAAG
LIERFLVFARARTVHPIAQPVEPILREAVEVVGPAAAHANVERVVEIAPALPEVVADGELLRQAFLNLCVNAVQAMQERG
GGTLVARARREGDGLVVEVSDSGPGLPRDIAAHVFDPFFTTKANGTGLGLAIVRQAAEAHGGTVEVESAPGHGATFRIRL
PVAPAEPAAAGAGAAP

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=240, Percent_Identity=35.4166666666667, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1790436, Length=224, Percent_Identity=35.7142857142857, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI1790300, Length=256, Percent_Identity=29.6875, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI48994928, Length=125, Percent_Identity=39.2, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87081816, Length=328, Percent_Identity=28.0487804878049, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI145693157, Length=232, Percent_Identity=28.8793103448276, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786600, Length=295, Percent_Identity=26.4406779661017, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786912, Length=251, Percent_Identity=29.4820717131474, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789808, Length=309, Percent_Identity=28.1553398058252, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1789149, Length=443, Percent_Identity=22.1218961625282, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790567, Length=95, Percent_Identity=37.8947368421053, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1790861, Length=359, Percent_Identity=23.9554317548747, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52520; Mature: 52389

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRLKLFVLIAGVIIFAMSGVTAVALWREVVRGQELLAREGVAIASTAATAAAHWVRAD
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
GVDPGGASALPAVLERVVASAPLDRAWIVDRTGKVLACVTRTEEACPEGAPPSEFQLAES
CCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCHHHCCCCCCCCHHHHHHH
PLQALGRLLQPEGIVASAPILRSGAVVGAVRVDFTHEEVVGNARNLAWGASIVAAFWIFV
HHHHHHHHCCCCCCEECCCHHHCCCEEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHH
GQLLAAIFLRRVTSPLVRLSEAAESLAEERGVRLEEPEERELADLVRAFNDMSRRLDDRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SENQRLIAELEARVAQKTREVLRADRLATLGGIAAGFAHEIGNSLNVIRGYASVAARELP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
ADAEVKSDVEAIRREVTRAAGLIERFLVFARARTVHPIAQPVEPILREAVEVVGPAAAHA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHH
NVERVVEIAPALPEVVADGELLRQAFLNLCVNAVQAMQERGGGTLVARARREGDGLVVEV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCCEEEEE
SDSGPGLPRDIAAHVFDPFFTTKANGTGLGLAIVRQAAEAHGGTVEVESAPGHGATFRIR
CCCCCCCCHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEE
LPVAPAEPAAAGAGAAP
ECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TLRLKLFVLIAGVIIFAMSGVTAVALWREVVRGQELLAREGVAIASTAATAAAHWVRAD
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
GVDPGGASALPAVLERVVASAPLDRAWIVDRTGKVLACVTRTEEACPEGAPPSEFQLAES
CCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCHHHCCCCCCCCHHHHHHH
PLQALGRLLQPEGIVASAPILRSGAVVGAVRVDFTHEEVVGNARNLAWGASIVAAFWIFV
HHHHHHHHCCCCCCEECCCHHHCCCEEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHH
GQLLAAIFLRRVTSPLVRLSEAAESLAEERGVRLEEPEERELADLVRAFNDMSRRLDDRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SENQRLIAELEARVAQKTREVLRADRLATLGGIAAGFAHEIGNSLNVIRGYASVAARELP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
ADAEVKSDVEAIRREVTRAAGLIERFLVFARARTVHPIAQPVEPILREAVEVVGPAAAHA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHH
NVERVVEIAPALPEVVADGELLRQAFLNLCVNAVQAMQERGGGTLVARARREGDGLVVEV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCCEEEEE
SDSGPGLPRDIAAHVFDPFFTTKANGTGLGLAIVRQAAEAHGGTVEVESAPGHGATFRIR
CCCCCCCCHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEE
LPVAPAEPAAAGAGAAP
ECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]