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The map label for this gene is paaK [H]

Identifier: 153002920

GI number: 153002920

Start: 54428

End: 55768

Strand: Reverse

Name: paaK [H]

Synonym: Anae109_0041

Alternate gene names: 153002920

Gene position: 55768-54428 (Counterclockwise)

Preceding gene: 153002921

Following gene: 153002919

Centisome position: 1.06

GC content: 71.96

Gene sequence:

>1341_bases
TTGACGACCCAGTGGAACGACGCGCCGGGAGGCTTCCACCCCGCGAGCGCGCCCGACTTCCTGCCGCGGCGCGAGCTCGC
CCGGCTCCAGCTCGGCCGGCTGCAGTCGGTCGTCGCCCGCGCCTACGCGCGCGTGCCGCTCTTCCGCGGACGGATGGAGG
AGCGCGGCCTCTCGCCCGCCGACGTGCGCTCGCTCGAGGACCTCGCGCGGCTGCCCTTCACGGTCAAGACGGACCTGCGC
GACACCTACCCGTTCGGCCTGTTCGCGAGCCCGATGGAGGAGGTCGTCCGCCTCCACGCGTCCTCCGGCACGACCGGCAA
GCCCATCGTGGTCGCCTACACCGAGGCGGACCTGCGGGTGTGGACGAGCGTGATGGTCCGCACGTTCGCGGCCTGCGGCC
TCCACCGCGGCGACGTGATCCAGAACGCCTACGGGTACGGGCTCTTCACCGGCGGCCTCGGCGCCCACTACGGCGGCGAG
GCCCTCGGCGCCACGGTGATCCCCATCTCCGGCGGCAACACCGAGCGCCAGCTCATGGTGCTCCAGGACTTCCGGGTCAC
CGCCATCTGCTGCACCCCCTCCTACATGCTCCACCTCGTCGAGCGCGCCCGCGAGGCGGGCATCTCCTTCGAGCGGCTGC
AGGTGGGGGTCTTCGGCGCGGAGCCCTGGTCCGAGGAGATGCGCCGCCACATCGAGGCAACCGCCGGCATCCGGGCGCAC
GACATCTACGGCCTCTCCGAGATCATCGGCCCGGGCGTCGGGATCGAGTGCCAGCGGCGCGAGGGGCTCCACCTCTTCGA
GGACCACTTCTTCCCGGAGATCATCGATCCCGAGACGGGCGACGTCCTCCCCGACGGCGCGGAGGGCGAGCTCGTCCTCA
CCACGCTCTCGAAGGAGGCGATGCCGATGATCCGCTACCGCACGCGCGACATCACGGCGCTCCTCCCGGAGCCCTGCGCC
TGCGGCCGCACCATCCGCCGCATCCGCCGCATCGGCCGCCGCTCCGACGACATGCTCATCGTCCGCGGCGTGAACGTGTT
CCCGTCGCAGATCGAGGCCGCGCTCCTCGCCGTCGAGGGCACCCTGCCGCACTACCAGCTCGTCCTCACCCGCGAGCACG
GGCTCGACGAGATGGAGGTGCAGGTGGAGGTGACGCCGGAGGTGTTCTCCGACACCATCGGCGCGATGGAGGGGCTGCGG
CGCCGGCTGGAGGCGGCGATCGACCACGTCGTCGGCATCCGCGCGAAGGTGACGCTCGTCGCGCCCCGCACCCTCGCCCG
CAGCGAGGGCAAGGCGAAGCGCGTCTCGGATCGCCGCAACATCCAAGGAGGGGTTTCGTGA

Upstream 100 bases:

>100_bases
GGGCGTTCCGGCTCGGCCGCGAGGCGGCGGGCCGGGCCGGGTAGGGGCGGCGGGACCTTCACGGACGGTGGGGCGGGGAT
CGACGAAGAGGAGAGCTTCC

Downstream 100 bases:

>100_bases
AGATCCGCCAGCTCTCGCTGTTCCTCGAGAACCGCCCCGGCCAGCTGCGCTTCCCCTGCAAGGTGCTGGGCGACGCCGGC
ATCGACATCCTCACCATGTC

Product: phenylacetate--CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MTTQWNDAPGGFHPASAPDFLPRRELARLQLGRLQSVVARAYARVPLFRGRMEERGLSPADVRSLEDLARLPFTVKTDLR
DTYPFGLFASPMEEVVRLHASSGTTGKPIVVAYTEADLRVWTSVMVRTFAACGLHRGDVIQNAYGYGLFTGGLGAHYGGE
ALGATVIPISGGNTERQLMVLQDFRVTAICCTPSYMLHLVERAREAGISFERLQVGVFGAEPWSEEMRRHIEATAGIRAH
DIYGLSEIIGPGVGIECQRREGLHLFEDHFFPEIIDPETGDVLPDGAEGELVLTTLSKEAMPMIRYRTRDITALLPEPCA
CGRTIRRIRRIGRRSDDMLIVRGVNVFPSQIEAALLAVEGTLPHYQLVLTREHGLDEMEVQVEVTPEVFSDTIGAMEGLR
RRLEAAIDHVVGIRAKVTLVAPRTLARSEGKAKRVSDRRNIQGGVS

Sequences:

>Translated_446_residues
MTTQWNDAPGGFHPASAPDFLPRRELARLQLGRLQSVVARAYARVPLFRGRMEERGLSPADVRSLEDLARLPFTVKTDLR
DTYPFGLFASPMEEVVRLHASSGTTGKPIVVAYTEADLRVWTSVMVRTFAACGLHRGDVIQNAYGYGLFTGGLGAHYGGE
ALGATVIPISGGNTERQLMVLQDFRVTAICCTPSYMLHLVERAREAGISFERLQVGVFGAEPWSEEMRRHIEATAGIRAH
DIYGLSEIIGPGVGIECQRREGLHLFEDHFFPEIIDPETGDVLPDGAEGELVLTTLSKEAMPMIRYRTRDITALLPEPCA
CGRTIRRIRRIGRRSDDMLIVRGVNVFPSQIEAALLAVEGTLPHYQLVLTREHGLDEMEVQVEVTPEVFSDTIGAMEGLR
RRLEAAIDHVVGIRAKVTLVAPRTLARSEGKAKRVSDRRNIQGGVS
>Mature_445_residues
TTQWNDAPGGFHPASAPDFLPRRELARLQLGRLQSVVARAYARVPLFRGRMEERGLSPADVRSLEDLARLPFTVKTDLRD
TYPFGLFASPMEEVVRLHASSGTTGKPIVVAYTEADLRVWTSVMVRTFAACGLHRGDVIQNAYGYGLFTGGLGAHYGGEA
LGATVIPISGGNTERQLMVLQDFRVTAICCTPSYMLHLVERAREAGISFERLQVGVFGAEPWSEEMRRHIEATAGIRAHD
IYGLSEIIGPGVGIECQRREGLHLFEDHFFPEIIDPETGDVLPDGAEGELVLTTLSKEAMPMIRYRTRDITALLPEPCAC
GRTIRRIRRIGRRSDDMLIVRGVNVFPSQIEAALLAVEGTLPHYQLVLTREHGLDEMEVQVEVTPEVFSDTIGAMEGLRR
RLEAAIDHVVGIRAKVTLVAPRTLARSEGKAKRVSDRRNIQGGVS

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=424, Percent_Identity=51.8867924528302, Blast_Score=417, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 49248; Mature: 49117

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQWNDAPGGFHPASAPDFLPRRELARLQLGRLQSVVARAYARVPLFRGRMEERGLSPA
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHCCCCHH
DVRSLEDLARLPFTVKTDLRDTYPFGLFASPMEEVVRLHASSGTTGKPIVVAYTEADLRV
HHHHHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHH
WTSVMVRTFAACGLHRGDVIQNAYGYGLFTGGLGAHYGGEALGATVIPISGGNTERQLMV
HHHHHHHHHHHHCCCCCHHHHCCCCCEEEECCCCCCCCCCCCCCEEEEECCCCCCCEEEE
LQDFRVTAICCTPSYMLHLVERAREAGISFERLQVGVFGAEPWSEEMRRHIEATAGIRAH
EECCCEEEEEECHHHHHHHHHHHHHHCCCEEHEEEEEECCCCHHHHHHHHHHHHCCCCHH
DIYGLSEIIGPGVGIECQRREGLHLFEDHFFPEIIDPETGDVLPDGAEGELVLTTLSKEA
HHCCHHHHHCCCCCCEECCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHH
MPMIRYRTRDITALLPEPCACGRTIRRIRRIGRRSDDMLIVRGVNVFPSQIEAALLAVEG
HHHHHHHCCCHHEECCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHEEEEC
TLPHYQLVLTREHGLDEMEVQVEVTPEVFSDTIGAMEGLRRRLEAAIDHVVGIRAKVTLV
CCCCEEEEEECCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEE
APRTLARSEGKAKRVSDRRNIQGGVS
CCHHHHHCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TTQWNDAPGGFHPASAPDFLPRRELARLQLGRLQSVVARAYARVPLFRGRMEERGLSPA
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHCCCCHH
DVRSLEDLARLPFTVKTDLRDTYPFGLFASPMEEVVRLHASSGTTGKPIVVAYTEADLRV
HHHHHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHH
WTSVMVRTFAACGLHRGDVIQNAYGYGLFTGGLGAHYGGEALGATVIPISGGNTERQLMV
HHHHHHHHHHHHCCCCCHHHHCCCCCEEEECCCCCCCCCCCCCCEEEEECCCCCCCEEEE
LQDFRVTAICCTPSYMLHLVERAREAGISFERLQVGVFGAEPWSEEMRRHIEATAGIRAH
EECCCEEEEEECHHHHHHHHHHHHHHCCCEEHEEEEEECCCCHHHHHHHHHHHHCCCCHH
DIYGLSEIIGPGVGIECQRREGLHLFEDHFFPEIIDPETGDVLPDGAEGELVLTTLSKEA
HHCCHHHHHCCCCCCEECCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHH
MPMIRYRTRDITALLPEPCACGRTIRRIRRIGRRSDDMLIVRGVNVFPSQIEAALLAVEG
HHHHHHHCCCHHEECCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHEEEEC
TLPHYQLVLTREHGLDEMEVQVEVTPEVFSDTIGAMEGLRRRLEAAIDHVVGIRAKVTLV
CCCCEEEEEECCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEE
APRTLARSEGKAKRVSDRRNIQGGVS
CCHHHHHCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]