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The map label for this gene is argS [H]

Identifier: 152977542

GI number: 152977542

Start: 3936978

End: 3938648

Strand: Reverse

Name: argS [H]

Synonym: Bcer98_3878

Alternate gene names: 152977542

Gene position: 3938648-3936978 (Counterclockwise)

Preceding gene: 152977543

Following gene: 152977538

Centisome position: 96.37

GC content: 38.12

Gene sequence:

>1671_bases
ATGAACTCTTTAGAACAAGTAAAAGAATTGATTAAAGAAGAAATTAAAGCTGCTGTATTAAAAGCAGAATTAGCAACAGA
AGAACAAATTCCAAATGTTATATTGGAAACTCCAAAGGATAAAACACACGGTGACTTCTCTACAAATATGGCAATGCAGT
TAGCGCGCGTTGCGAAAAAAGCTCCTCGTATGATTGCAGAAGAGTTAATTACAAACTTTAATAAGGAAAAAGCCTCTATT
GAAAAAATTGAAATCGCTGGGCCTGGTTTTATTAACTTCCACATGGATAACAGTTATTTAACAGATTTAATTCCAACGAT
TGTAAAAGCTGGTGAAGCTTACGGTGAAACAAACACTGGTAAAGGTGAAAAAATTCAAGTTGAGTTCGTATCTGCAAATC
CAACAGGAGATCTTCACTTAGGACATGCGCGCGGAGCAGCAGTCGGTGACACTTTATGTAACGTATTGGCAAAAGCAGGA
TACGACGTATCTCGTGAGTACTACATTAACGATGCAGGCAACCAAATTCACAATCTAGCTCTTTCAGTTGAAGCACGTTA
TATGCAAGCATTAGGTTTAGAGAAAGAAATGCCAGAAGATGGATATCACGGTGCGGATATTATGGAGATCGGAAAACGTT
TGGCTGAAGAATTTGGCGATCGCTATGTAAAGGCTGATGAAAAAGAAAGCTATGAATTCTACCGTCAATACGGTTTAAAA
TATGAATTAGCGAAACTTCAAAAAGACTTAGATAGCTTCCGTGTGAAGTTTGATGTATGGTTCTCTGAGACATCATTATA
TAAAAACGGTAAAATTGACGCAGCACTTGCTGTATTAAAAGAGCGTAATGAAATCTTTGAAGAAGGTGGGGCAACTTGGT
TCCGCTCAACAGCTTACGGTGATGACAAAGACCGTGTATTAATTAAAAAAGATGGTTCTTACACATACTTAACACCAGAT
ATTGCGTATCACCGCGATAAATTAGAGCGTGGATTTGATAAACTGATCAATATTTGGGGTGCGGATCATCATGGTTACAT
TCCTCGTATGAAAGCTGCAATTCAAGCGCTTGGCTATGAGAAAGAAACACTTGAAGTAGAAATTATCCAAATGGTACAAC
TATACCAAAATGGTGAAAAAGTGAAGATGAGTAAGCGTACAGGTAAAGCAGTTACCCTTCGTGAACTTATGGAAGAAGTA
GGCGTGGACGCAATGCGTTACTTCTTTGCAATGCGCAGCGGTGATTCTCATTTAGACTTTGATATGGATTTAGCTGTATC
AAAATCAAATGAAAACCCAGTATACTATGCACAATATGCTCACGCGCGCGTATGCAGCATCCTTCGTCAAGGAGAAGAGC
TTGGATTACATGCAGGTGGAGATGTAAACTATAAACTGGTTGCTTCTGAAAAAGAAATTGACTTACTGAAAAAACTTGGT
GAATTCCCAGCAGCAGTTGCAGAAGCAGCACAAAAACGTCTACCGCACCGTATTACAAGCTATGCATTTGAATTAGCAGC
AGCCCTTCATAGCTTCTACAATGCAGAAAAAGTATTAAATCAAGATAACTTAGAATTAAGTAAAGCTCGTTATGAATTAA
TGAAAGCAGTGCGCATTACACTTCAAAATGCATTAGCATTAGTAGGAGTATCAGCACCAGAAAAAATGTAA

Upstream 100 bases:

>100_bases
AAAAGAAAAAAGGACAGCTCTTTTTAGCGTACGCATTGCTTCTAAGTGAACAAGAAGCTGGCAGATATACAATTACGATT
AATTTAAAGGAGGCAAAATA

Downstream 100 bases:

>100_bases
TAAAGAAAAGCAAAAAAAAGGCAATCACACCATATTGTGATCGCCTTTTTTTTTCATTGAATTGTATAAGTAACAGAAAA
ACTAATAGGGCTATAGTAAG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase 1; ArgRS 1 [H]

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MNSLEQVKELIKEEIKAAVLKAELATEEQIPNVILETPKDKTHGDFSTNMAMQLARVAKKAPRMIAEELITNFNKEKASI
EKIEIAGPGFINFHMDNSYLTDLIPTIVKAGEAYGETNTGKGEKIQVEFVSANPTGDLHLGHARGAAVGDTLCNVLAKAG
YDVSREYYINDAGNQIHNLALSVEARYMQALGLEKEMPEDGYHGADIMEIGKRLAEEFGDRYVKADEKESYEFYRQYGLK
YELAKLQKDLDSFRVKFDVWFSETSLYKNGKIDAALAVLKERNEIFEEGGATWFRSTAYGDDKDRVLIKKDGSYTYLTPD
IAYHRDKLERGFDKLINIWGADHHGYIPRMKAAIQALGYEKETLEVEIIQMVQLYQNGEKVKMSKRTGKAVTLRELMEEV
GVDAMRYFFAMRSGDSHLDFDMDLAVSKSNENPVYYAQYAHARVCSILRQGEELGLHAGGDVNYKLVASEKEIDLLKKLG
EFPAAVAEAAQKRLPHRITSYAFELAAALHSFYNAEKVLNQDNLELSKARYELMKAVRITLQNALALVGVSAPEKM

Sequences:

>Translated_556_residues
MNSLEQVKELIKEEIKAAVLKAELATEEQIPNVILETPKDKTHGDFSTNMAMQLARVAKKAPRMIAEELITNFNKEKASI
EKIEIAGPGFINFHMDNSYLTDLIPTIVKAGEAYGETNTGKGEKIQVEFVSANPTGDLHLGHARGAAVGDTLCNVLAKAG
YDVSREYYINDAGNQIHNLALSVEARYMQALGLEKEMPEDGYHGADIMEIGKRLAEEFGDRYVKADEKESYEFYRQYGLK
YELAKLQKDLDSFRVKFDVWFSETSLYKNGKIDAALAVLKERNEIFEEGGATWFRSTAYGDDKDRVLIKKDGSYTYLTPD
IAYHRDKLERGFDKLINIWGADHHGYIPRMKAAIQALGYEKETLEVEIIQMVQLYQNGEKVKMSKRTGKAVTLRELMEEV
GVDAMRYFFAMRSGDSHLDFDMDLAVSKSNENPVYYAQYAHARVCSILRQGEELGLHAGGDVNYKLVASEKEIDLLKKLG
EFPAAVAEAAQKRLPHRITSYAFELAAALHSFYNAEKVLNQDNLELSKARYELMKAVRITLQNALALVGVSAPEKM
>Mature_556_residues
MNSLEQVKELIKEEIKAAVLKAELATEEQIPNVILETPKDKTHGDFSTNMAMQLARVAKKAPRMIAEELITNFNKEKASI
EKIEIAGPGFINFHMDNSYLTDLIPTIVKAGEAYGETNTGKGEKIQVEFVSANPTGDLHLGHARGAAVGDTLCNVLAKAG
YDVSREYYINDAGNQIHNLALSVEARYMQALGLEKEMPEDGYHGADIMEIGKRLAEEFGDRYVKADEKESYEFYRQYGLK
YELAKLQKDLDSFRVKFDVWFSETSLYKNGKIDAALAVLKERNEIFEEGGATWFRSTAYGDDKDRVLIKKDGSYTYLTPD
IAYHRDKLERGFDKLINIWGADHHGYIPRMKAAIQALGYEKETLEVEIIQMVQLYQNGEKVKMSKRTGKAVTLRELMEEV
GVDAMRYFFAMRSGDSHLDFDMDLAVSKSNENPVYYAQYAHARVCSILRQGEELGLHAGGDVNYKLVASEKEIDLLKKLG
EFPAAVAEAAQKRLPHRITSYAFELAAALHSFYNAEKVLNQDNLELSKARYELMKAVRITLQNALALVGVSAPEKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=612, Percent_Identity=24.6732026143791, Blast_Score=121, Evalue=2e-27,
Organism=Escherichia coli, GI1788184, Length=597, Percent_Identity=26.1306532663317, Blast_Score=137, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71985061, Length=583, Percent_Identity=23.156089193825, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI71985068, Length=538, Percent_Identity=23.6059479553903, Blast_Score=105, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6320548, Length=528, Percent_Identity=25.7575757575758, Blast_Score=137, Evalue=6e-33,
Organism=Drosophila melanogaster, GI18859963, Length=567, Percent_Identity=24.6913580246914, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI28571570, Length=604, Percent_Identity=23.0132450331126, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 62586; Mature: 62586

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSLEQVKELIKEEIKAAVLKAELATEEQIPNVILETPKDKTHGDFSTNMAMQLARVAKK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHH
APRMIAEELITNFNKEKASIEKIEIAGPGFINFHMDNSYLTDLIPTIVKAGEAYGETNTG
HHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCC
KGEKIQVEFVSANPTGDLHLGHARGAAVGDTLCNVLAKAGYDVSREYYINDAGNQIHNLA
CCCEEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHH
LSVEARYMQALGLEKEMPEDGYHGADIMEIGKRLAEEFGDRYVKADEKESYEFYRQYGLK
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHCCC
YELAKLQKDLDSFRVKFDVWFSETSLYKNGKIDAALAVLKERNEIFEEGGATWFRSTAYG
HHHHHHHHHHHHHEEEEEEEECCCHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCC
DDKDRVLIKKDGSYTYLTPDIAYHRDKLERGFDKLINIWGADHHGYIPRMKAAIQALGYE
CCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
KETLEVEIIQMVQLYQNGEKVKMSKRTGKAVTLRELMEEVGVDAMRYFFAMRSGDSHLDF
CHHHHHHHHHHHHHHHCCCEEEEHHCCCCCHHHHHHHHHHCHHHHHHHHHHCCCCCCCCC
DMDLAVSKSNENPVYYAQYAHARVCSILRQGEELGLHAGGDVNYKLVASEKEIDLLKKLG
CEEEEEECCCCCCEEEEHHHHHHHHHHHHCCHHCCCCCCCCCCEEEEECCHHHHHHHHHH
EFPAAVAEAAQKRLPHRITSYAFELAAALHSFYNAEKVLNQDNLELSKARYELMKAVRIT
HCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LQNALALVGVSAPEKM
HHHHHHHEECCCCCCC
>Mature Secondary Structure
MNSLEQVKELIKEEIKAAVLKAELATEEQIPNVILETPKDKTHGDFSTNMAMQLARVAKK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHH
APRMIAEELITNFNKEKASIEKIEIAGPGFINFHMDNSYLTDLIPTIVKAGEAYGETNTG
HHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCC
KGEKIQVEFVSANPTGDLHLGHARGAAVGDTLCNVLAKAGYDVSREYYINDAGNQIHNLA
CCCEEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHH
LSVEARYMQALGLEKEMPEDGYHGADIMEIGKRLAEEFGDRYVKADEKESYEFYRQYGLK
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHCCC
YELAKLQKDLDSFRVKFDVWFSETSLYKNGKIDAALAVLKERNEIFEEGGATWFRSTAYG
HHHHHHHHHHHHHEEEEEEEECCCHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCC
DDKDRVLIKKDGSYTYLTPDIAYHRDKLERGFDKLINIWGADHHGYIPRMKAAIQALGYE
CCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
KETLEVEIIQMVQLYQNGEKVKMSKRTGKAVTLRELMEEVGVDAMRYFFAMRSGDSHLDF
CHHHHHHHHHHHHHHHCCCEEEEHHCCCCCHHHHHHHHHHCHHHHHHHHHHCCCCCCCCC
DMDLAVSKSNENPVYYAQYAHARVCSILRQGEELGLHAGGDVNYKLVASEKEIDLLKKLG
CEEEEEECCCCCCEEEEHHHHHHHHHHHHCCHHCCCCCCCCCCEEEEECCHHHHHHHHHH
EFPAAVAEAAQKRLPHRITSYAFELAAALHSFYNAEKVLNQDNLELSKARYELMKAVRIT
HCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LQNALALVGVSAPEKM
HHHHHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]