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The map label for this gene is nuoI [H]

Identifier: 152977482

GI number: 152977482

Start: 3875364

End: 3875783

Strand: Reverse

Name: nuoI [H]

Synonym: Bcer98_3814

Alternate gene names: 152977482

Gene position: 3875783-3875364 (Counterclockwise)

Preceding gene: 152977483

Following gene: 152977481

Centisome position: 94.83

GC content: 34.29

Gene sequence:

>420_bases
ATGAAAGGGTTATTGAAAGGATTGAAATATACGCTAAGTAATTTGAGCAAGAAAAAGGTGACATACGATTATCCAAATCA
ACCATTGCCACTGCCAGATCGGTTTCGCGGCATTCAAAAATTCTATCCGGAAAAGTGTATTGTTTGTAATCAATGTGCCA
ATATTTGTCCGACCAATTGTATTCAGTTAACCGGAAAAAAGCATCCAGATCCTACGAAAAAAGGGAAAATCATTGATACG
TATGATATTAATTTTGAAATTTGTATTCTATGTGATTTATGTACGGAAGTGTGTCCGACAGAGGCTATTGTTATGACAAA
TAACTTTGAACTAGCGGAGTATACACGTGATGATTTATTTAAAAACTTGCAATGGTTAGATGAAAATGATGAAAACGTTA
GAAAGGAGAATAAGGCATGA

Upstream 100 bases:

>100_bases
TGGCTGGAAGGTACTATTACCGATTGCATTGGCTAATATCTTTTTAACGGCATTGATTAAGGAGTTGTTCTTCTAATCTG
TGAGGAGGTGCCAGCAAGAG

Downstream 100 bases:

>100_bases
CCGGTGAGTTGATTGCATTTTTTATATTATCTTTCACTGCGGTTATGGGCGGAGTGTTTATGCTGAATGTAACGAAAGTA
ATGCATATGATGCTTGCCCT

Product: NADH dehydrogenase subunit I

Products: NA

Alternate protein names: NADH dehydrogenase I subunit I; NDH-1 subunit I [H]

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MKGLLKGLKYTLSNLSKKKVTYDYPNQPLPLPDRFRGIQKFYPEKCIVCNQCANICPTNCIQLTGKKHPDPTKKGKIIDT
YDINFEICILCDLCTEVCPTEAIVMTNNFELAEYTRDDLFKNLQWLDENDENVRKENKA

Sequences:

>Translated_139_residues
MKGLLKGLKYTLSNLSKKKVTYDYPNQPLPLPDRFRGIQKFYPEKCIVCNQCANICPTNCIQLTGKKHPDPTKKGKIIDT
YDINFEICILCDLCTEVCPTEAIVMTNNFELAEYTRDDLFKNLQWLDENDENVRKENKA
>Mature_139_residues
MKGLLKGLKYTLSNLSKKKVTYDYPNQPLPLPDRFRGIQKFYPEKCIVCNQCANICPTNCIQLTGKKHPDPTKKGKIIDT
YDINFEICILCDLCTEVCPTEAIVMTNNFELAEYTRDDLFKNLQWLDENDENVRKENKA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1143

COG function: function code C; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI4505371, Length=141, Percent_Identity=36.1702127659575, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788617, Length=108, Percent_Identity=43.5185185185185, Blast_Score=84, Evalue=5e-18,
Organism=Escherichia coli, GI1789075, Length=106, Percent_Identity=31.1320754716981, Blast_Score=67, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17555194, Length=138, Percent_Identity=34.7826086956522, Blast_Score=86, Evalue=8e-18,
Organism=Drosophila melanogaster, GI17864306, Length=128, Percent_Identity=36.71875, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR010226 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 16086; Mature: 16086

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
6.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGLLKGLKYTLSNLSKKKVTYDYPNQPLPLPDRFRGIQKFYPEKCIVCNQCANICPTNC
CCHHHHHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCE
IQLTGKKHPDPTKKGKIIDTYDINFEICILCDLCTEVCPTEAIVMTNNFELAEYTRDDLF
EEECCCCCCCCCCCCCEEEEEECCEEEEHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
KNLQWLDENDENVRKENKA
HHHHHCCCCCHHHHHCCCC
>Mature Secondary Structure
MKGLLKGLKYTLSNLSKKKVTYDYPNQPLPLPDRFRGIQKFYPEKCIVCNQCANICPTNC
CCHHHHHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCE
IQLTGKKHPDPTKKGKIIDTYDINFEICILCDLCTEVCPTEAIVMTNNFELAEYTRDDLF
EEECCCCCCCCCCCCCEEEEEECCEEEEHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
KNLQWLDENDENVRKENKA
HHHHHCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA