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The map label for this gene is fabZ

Identifier: 152977465

GI number: 152977465

Start: 3858989

End: 3859423

Strand: Reverse

Name: fabZ

Synonym: Bcer98_3797

Alternate gene names: 152977465

Gene position: 3859423-3858989 (Counterclockwise)

Preceding gene: 152977466

Following gene: 152977464

Centisome position: 94.43

GC content: 41.61

Gene sequence:

>435_bases
ATGTTAAACATAGAACAAATTAAAGAAATCATTCCGCACCGTTACCCATTCTTGCTCGTTGATCAAGTATTAGAAGTAGA
AGAGGGAAAGCGCGCAGTCGGAATTAAAAATGTATCTGCAAATGAAGAATTCTTTAATGGGCATTTCCCTGAATATGCAG
TCATGCCAGGGGTATTAATTGTGGAAGCGTTGGCTCAAGTTGGAGCAATTGCGATATTAAAGAAAGAAGAAAATCGCGGA
CGCCTAGCCTTCTTTGGAGGTATTGATCATTGCCGCTTTAAAAAACAAGTCCGCCCGGGTGATCAACTTCGCTTAGAAGT
GGAATTGACACGCGTACGCGGTCCGATTGGAAAAGGAAAAGCTGTCGCAACGGTAGATGGTGAAATTGTCTGTGAAGCAG
AAATTACATTTGCTCTTGGAGAAAAGAAGGAATAA

Upstream 100 bases:

>100_bases
TATAGCGTTTCTTTTTTTATAATGACAAACCACTGGCAAAATGGGATAATAACATATATCCTAGTGGTAAGACCAATATG
GAAGAAGGAGCGATATTTTC

Downstream 100 bases:

>100_bases
TATAAATTTAAATAGACGGATAACGAAAAATGTTATTCGTCTATTTTTTAGATGAACATATTGGTGTAGTATTTGTGGCT
GGAGAGGAATATCTTGAGGG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MLNIEQIKEIIPHRYPFLLVDQVLEVEEGKRAVGIKNVSANEEFFNGHFPEYAVMPGVLIVEALAQVGAIAILKKEENRG
RLAFFGGIDHCRFKKQVRPGDQLRLEVELTRVRGPIGKGKAVATVDGEIVCEAEITFALGEKKE

Sequences:

>Translated_144_residues
MLNIEQIKEIIPHRYPFLLVDQVLEVEEGKRAVGIKNVSANEEFFNGHFPEYAVMPGVLIVEALAQVGAIAILKKEENRG
RLAFFGGIDHCRFKKQVRPGDQLRLEVELTRVRGPIGKGKAVATVDGEIVCEAEITFALGEKKE
>Mature_144_residues
MLNIEQIKEIIPHRYPFLLVDQVLEVEEGKRAVGIKNVSANEEFFNGHFPEYAVMPGVLIVEALAQVGAIAILKKEENRG
RLAFFGGIDHCRFKKQVRPGDQLRLEVELTRVRGPIGKGKAVATVDGEIVCEAEITFALGEKKE

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=139, Percent_Identity=50.3597122302158, Blast_Score=138, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_BACCN (A7GV29)

Other databases:

- EMBL:   CP000764
- RefSeq:   YP_001376982.1
- ProteinModelPortal:   A7GV29
- SMR:   A7GV29
- STRING:   A7GV29
- EnsemblBacteria:   EBBACT00000038489
- GeneID:   5347330
- GenomeReviews:   CP000764_GR
- KEGG:   bcy:Bcer98_3797
- eggNOG:   COG0764
- GeneTree:   EBGT00050000002061
- HOGENOM:   HBG433282
- OMA:   NVSANES
- ProtClustDB:   PRK00006
- BioCyc:   BCER315749:BCER98_3797-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 16041; Mature: 16041

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: ACT_SITE 48-48

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNIEQIKEIIPHRYPFLLVDQVLEVEEGKRAVGIKNVSANEEFFNGHFPEYAVMPGVLI
CCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHCCCCCCCHHHCCHHHH
VEALAQVGAIAILKKEENRGRLAFFGGIDHCRFKKQVRPGDQLRLEVELTRVRGPIGKGK
HHHHHHHCEEEEEEECCCCCEEEEECCCCHHHHHHHCCCCCEEEEEEEEEEECCCCCCCC
AVATVDGEIVCEAEITFALGEKKE
EEEEECCCEEEEEEEEEECCCCCC
>Mature Secondary Structure
MLNIEQIKEIIPHRYPFLLVDQVLEVEEGKRAVGIKNVSANEEFFNGHFPEYAVMPGVLI
CCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHCCCCCCCHHHCCHHHH
VEALAQVGAIAILKKEENRGRLAFFGGIDHCRFKKQVRPGDQLRLEVELTRVRGPIGKGK
HHHHHHHCEEEEEEECCCCCEEEEECCCCHHHHHHHCCCCCEEEEEEEEEEECCCCCCCC
AVATVDGEIVCEAEITFALGEKKE
EEEEECCCEEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA