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The map label for this gene is pgtP [H]

Identifier: 152977458

GI number: 152977458

Start: 3851520

End: 3852860

Strand: Reverse

Name: pgtP [H]

Synonym: Bcer98_3790

Alternate gene names: 152977458

Gene position: 3852860-3851520 (Counterclockwise)

Preceding gene: 152977459

Following gene: 152977456

Centisome position: 94.27

GC content: 37.06

Gene sequence:

>1341_bases
ATGTTTAAATGGTTAAAACCAGCACCAGCGATAGAACGATTACCAACGGATATGATTGATAAAGTATACAGACTGTTACG
CATCCGCGTGTTAATTGGGATTTCAGTTGGATATGCAGCGTATTATTTAGTTCGTAGTAACTTTACGTTATCAAGTACGT
ATTTAATGAAGGAATACGGTTTTAGTACAACGCAAATTGGTTTATTAGGTTCCGTTGTTGCGATTGTATATGGACTAAGT
AAGTTCTTTATGGGGAATTTATCAGATAAAGCGTATGCTCAGCGTTTTATTGCGGTTGGTTTATTCTTATCAGCAATTAT
AAATATTTGTTTTGGGTTTGCATCTTCATTTGGAATGATTTTAACATTATTAGTTTTCAATAATATTTTCCAAGGGATGG
GGGCACCGCCTTGTAGTACCGTAATGACAAAGTGGTTCTCAAAGAAAGAGCGTGGTACCAAAACAGGGCTTTGGAATATT
TCACATAACGTCGGCGGCATGCTTGTACCACCACTTGTTGGTATCGGTGTAGGGATTTTCGGTGAAAGTCATTGGCAAGC
CGGTGTGTTTATTTTCCCGGCGATAATTGCAATGGTAATTTCAGTTCTTATGTGGATCAATGCAAAGGATACACCAGAAT
CTGCTGGTCTTCCGCCAATTGATGAATATCGTAATGACTATGAAAATCTTGAAAAAGCAGACAATGCAAACAAAATGTCA
CCAAAAGACATTTTAATGAAATATGTTGTGAAAAATAAATTTGTTTGGTACTTATGTATTGCGAATGCATTCGTATACTT
AATTCGCTTTGGTGTTATTAACTGGGTACCAATTTACTTAACGACTGTAAAAGGATTTACGCAAGCGCAGTCCCATGCAG
CGTATTCTATTTTTGAAGGAATGGCAATTCCAAGCTCCTTACTAGTTGGTCTTTTAAGTGATAAATTATTTAAAGGAAAA
CGTATGCCACTATGCGTAATTAGTATGGCTGGTGTTGTTGTTGGAACGATTGTATATTGGCAGGCAACTAGCATATTGGT
TGTAAGTATTGCTGTTTCTATTATCGGTTGCTTAATTTACGTTCCTCAGTTCTTAATTGGTCTAAGTGCAATGGAATTAG
TACCGAAATTTGCAGTAGGTACAACAGTTGGTATGTGCGGTCTATTTGCTTATGTAGGAGGAAGCTTAACAGCGAACTTA
ATCATCGGATTCATGGTTGATCACTCTGGCTGGGATGGTTGCTTTATCTTACTACTTGCAGGTGGTATTCTATCAACATT
ATTCCTATTAATTGTACAACTTGGACACGAAAGAAAAAGTCCAGCGAACAAAACAGCATAA

Upstream 100 bases:

>100_bases
CCTGTGAGAAGAACAAATAAAGATATATCAAATAGTGGGCTTATCGAGATTTGGAATAGACAGCGTCTCTCTCAAAAGTA
GATAAAGGAGAAGAGATGGT

Downstream 100 bases:

>100_bases
TGATGTATAGAAAAGAGCAATCCAAAAAGAAATGTTTTTGGATTGCTCTTTTTATAATGGTTGAAGATTTATATGAGAAA
ATACAACTTTTCCTGTATTT

Product: phosphoglycerate transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MFKWLKPAPAIERLPTDMIDKVYRLLRIRVLIGISVGYAAYYLVRSNFTLSSTYLMKEYGFSTTQIGLLGSVVAIVYGLS
KFFMGNLSDKAYAQRFIAVGLFLSAIINICFGFASSFGMILTLLVFNNIFQGMGAPPCSTVMTKWFSKKERGTKTGLWNI
SHNVGGMLVPPLVGIGVGIFGESHWQAGVFIFPAIIAMVISVLMWINAKDTPESAGLPPIDEYRNDYENLEKADNANKMS
PKDILMKYVVKNKFVWYLCIANAFVYLIRFGVINWVPIYLTTVKGFTQAQSHAAYSIFEGMAIPSSLLVGLLSDKLFKGK
RMPLCVISMAGVVVGTIVYWQATSILVVSIAVSIIGCLIYVPQFLIGLSAMELVPKFAVGTTVGMCGLFAYVGGSLTANL
IIGFMVDHSGWDGCFILLLAGGILSTLFLLIVQLGHERKSPANKTA

Sequences:

>Translated_446_residues
MFKWLKPAPAIERLPTDMIDKVYRLLRIRVLIGISVGYAAYYLVRSNFTLSSTYLMKEYGFSTTQIGLLGSVVAIVYGLS
KFFMGNLSDKAYAQRFIAVGLFLSAIINICFGFASSFGMILTLLVFNNIFQGMGAPPCSTVMTKWFSKKERGTKTGLWNI
SHNVGGMLVPPLVGIGVGIFGESHWQAGVFIFPAIIAMVISVLMWINAKDTPESAGLPPIDEYRNDYENLEKADNANKMS
PKDILMKYVVKNKFVWYLCIANAFVYLIRFGVINWVPIYLTTVKGFTQAQSHAAYSIFEGMAIPSSLLVGLLSDKLFKGK
RMPLCVISMAGVVVGTIVYWQATSILVVSIAVSIIGCLIYVPQFLIGLSAMELVPKFAVGTTVGMCGLFAYVGGSLTANL
IIGFMVDHSGWDGCFILLLAGGILSTLFLLIVQLGHERKSPANKTA
>Mature_446_residues
MFKWLKPAPAIERLPTDMIDKVYRLLRIRVLIGISVGYAAYYLVRSNFTLSSTYLMKEYGFSTTQIGLLGSVVAIVYGLS
KFFMGNLSDKAYAQRFIAVGLFLSAIINICFGFASSFGMILTLLVFNNIFQGMGAPPCSTVMTKWFSKKERGTKTGLWNI
SHNVGGMLVPPLVGIGVGIFGESHWQAGVFIFPAIIAMVISVLMWINAKDTPESAGLPPIDEYRNDYENLEKADNANKMS
PKDILMKYVVKNKFVWYLCIANAFVYLIRFGVINWVPIYLTTVKGFTQAQSHAAYSIFEGMAIPSSLLVGLLSDKLFKGK
RMPLCVISMAGVVVGTIVYWQATSILVVSIAVSIIGCLIYVPQFLIGLSAMELVPKFAVGTTVGMCGLFAYVGGSLTANL
IIGFMVDHSGWDGCFILLLAGGILSTLFLLIVQLGHERKSPANKTA

Specific function: The phosphoglycerate transporter protein is a part of the PGT transport system. It is the membrane bound transporter for phosphoglycerate into salmonella [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=410, Percent_Identity=24.8780487804878, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI4503847, Length=410, Percent_Identity=24.8780487804878, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI256219483, Length=410, Percent_Identity=24.8780487804878, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI256219543, Length=432, Percent_Identity=24.0740740740741, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI256219564, Length=335, Percent_Identity=24.1791044776119, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI223717983, Length=398, Percent_Identity=22.8643216080402, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI38093649, Length=398, Percent_Identity=22.8643216080402, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1788573, Length=446, Percent_Identity=43.7219730941704, Blast_Score=375, Evalue=1e-105,
Organism=Escherichia coli, GI87082310, Length=438, Percent_Identity=34.4748858447489, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI2367259, Length=450, Percent_Identity=31.1111111111111, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI2367379, Length=446, Percent_Identity=25.3363228699552, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789515, Length=420, Percent_Identity=23.0952380952381, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87082320, Length=412, Percent_Identity=23.5436893203883, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1789152, Length=418, Percent_Identity=21.2918660287081, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17564204, Length=389, Percent_Identity=26.7352185089974, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17564202, Length=384, Percent_Identity=26.8229166666667, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17542316, Length=449, Percent_Identity=21.6035634743875, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24656866, Length=492, Percent_Identity=20.9349593495935, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45550478, Length=492, Percent_Identity=20.9349593495935, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24656861, Length=492, Percent_Identity=20.9349593495935, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48829; Mature: 48829

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 3042749 [H]