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The map label for this gene is yugH [H]

Identifier: 152977195

GI number: 152977195

Start: 3582103

End: 3583293

Strand: Reverse

Name: yugH [H]

Synonym: Bcer98_3512

Alternate gene names: 152977195

Gene position: 3583293-3582103 (Counterclockwise)

Preceding gene: 152977196

Following gene: 152977194

Centisome position: 87.67

GC content: 39.13

Gene sequence:

>1191_bases
ATGAAGCAGTTTGAACTATCTAGAGCAGCAGAGTCTTTACAGCCATCTGGTATTCGAAAGTTCTTTGATTTAGCAGCAGG
AATGAAAGGTGTTATTTCACTTGGTGTTGGAGAACCTGACTTTGTGACACCGTGGAATGTAAGGAAAGCCTGTATTCGTT
CGTTAGAAGAAGGGTATACAGCATACACGGCAAATGCAGGATTATTAGAACTACGTCAAGAAATAGCAAAGTATCTAAAA
AAACAATTTGAAGTTTCTTATGATCCAAATGACGAAATTATTGTGACAGTTGGAGCAAGCCAAGCGCTAGATGTGGCCAT
GCGTGCGATTGTGAATCCTGGTGACGAAGTGATTATTATAGAACCGAGCTTTGTGTCATATGCCCCCCTTGTTACATTGG
CAGGGGGCGTTCCAATACCGGTTGCAACATCTTTAGAGAACGCATTTAAAGTACAGCCAGAACAAATTGAAGCAGCGATT
ACAACAAAGACGAAAGCAATTTTGCTTTGTTCTCCAAATAATCCAACAGGGGCGCTTTTAAACAAATCTGAATTAGAAAA
GTTAGCAGAAATTGTAGAAAAATATAATTTAATTGTTCTATCAGATGAAATTTATGCGGAGCTTGTCTATGATGAAGCTT
ATACAAGTTTTGCTAGCATAAAGAATATGAGGGATCATACGATTTTAATTTCTGGATTTTCAAAAGGATTTGCAATGACA
GGATGGCGTCTTGGGATGATTGCAGCTCCTACTCATTTTTCATCATTCATGTTAAAAATTCATCAGTATTCTATGATGTG
CGCGCCAACAATGTCACAGTTTGCTGCGCTCGAAGCGCTTCGGTCCGGGAATGATGAAGTTATTCGAATGAGAGACAGTT
ACAAGAAGCGCCGCAACTTTATGACACAGTCGTTAAATGAGATGGGATTAACATGTCATGTACCGGGTGGTGCGTTTTAT
GTATTTCCTTCTATTTCTTCAACAGGATTGTCTTCAGCGGCATTTGCCGAGCAATTATTGATAGAGGAAAAAATTGCGGT
TGTACCAGGTAGTGTGTTTGGTGAAAGTGGTGAAGGGTTTATTCGTTGTTCTTATGCGACTTCACTTGAGCAACTTATGG
AAGCTATGAACAGAATGAAACGTTTTGTGGAGAATAAAAAAAGGACAAAACAGAATACGTTTTGTCCATAA

Upstream 100 bases:

>100_bases
CAGTCGTTTCAACAACAACTCATTTTATTTTGAAAAAATATAAACATGAGGGAATTATTTATGAAAATACAGATGATGAT
AAACGAATTGTGGTGACACC

Downstream 100 bases:

>100_bases
AAGGGGGGAATACTAGAAAGCCATGTGTTAGTATTCTATCCCAATATTTGAAAAATATACGTACTAGAGGGGATTTTTTT
ATGAATTTTGAATGAAAGAA

Product: hypothetical protein

Products: N-succinyl-2-L-amino-6-oxoheptanedioate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MKQFELSRAAESLQPSGIRKFFDLAAGMKGVISLGVGEPDFVTPWNVRKACIRSLEEGYTAYTANAGLLELRQEIAKYLK
KQFEVSYDPNDEIIVTVGASQALDVAMRAIVNPGDEVIIIEPSFVSYAPLVTLAGGVPIPVATSLENAFKVQPEQIEAAI
TTKTKAILLCSPNNPTGALLNKSELEKLAEIVEKYNLIVLSDEIYAELVYDEAYTSFASIKNMRDHTILISGFSKGFAMT
GWRLGMIAAPTHFSSFMLKIHQYSMMCAPTMSQFAALEALRSGNDEVIRMRDSYKKRRNFMTQSLNEMGLTCHVPGGAFY
VFPSISSTGLSSAAFAEQLLIEEKIAVVPGSVFGESGEGFIRCSYATSLEQLMEAMNRMKRFVENKKRTKQNTFCP

Sequences:

>Translated_396_residues
MKQFELSRAAESLQPSGIRKFFDLAAGMKGVISLGVGEPDFVTPWNVRKACIRSLEEGYTAYTANAGLLELRQEIAKYLK
KQFEVSYDPNDEIIVTVGASQALDVAMRAIVNPGDEVIIIEPSFVSYAPLVTLAGGVPIPVATSLENAFKVQPEQIEAAI
TTKTKAILLCSPNNPTGALLNKSELEKLAEIVEKYNLIVLSDEIYAELVYDEAYTSFASIKNMRDHTILISGFSKGFAMT
GWRLGMIAAPTHFSSFMLKIHQYSMMCAPTMSQFAALEALRSGNDEVIRMRDSYKKRRNFMTQSLNEMGLTCHVPGGAFY
VFPSISSTGLSSAAFAEQLLIEEKIAVVPGSVFGESGEGFIRCSYATSLEQLMEAMNRMKRFVENKKRTKQNTFCP
>Mature_396_residues
MKQFELSRAAESLQPSGIRKFFDLAAGMKGVISLGVGEPDFVTPWNVRKACIRSLEEGYTAYTANAGLLELRQEIAKYLK
KQFEVSYDPNDEIIVTVGASQALDVAMRAIVNPGDEVIIIEPSFVSYAPLVTLAGGVPIPVATSLENAFKVQPEQIEAAI
TTKTKAILLCSPNNPTGALLNKSELEKLAEIVEKYNLIVLSDEIYAELVYDEAYTSFASIKNMRDHTILISGFSKGFAMT
GWRLGMIAAPTHFSSFMLKIHQYSMMCAPTMSQFAALEALRSGNDEVIRMRDSYKKRRNFMTQSLNEMGLTCHVPGGAFY
VFPSISSTGLSSAAFAEQLLIEEKIAVVPGSVFGESGEGFIRCSYATSLEQLMEAMNRMKRFVENKKRTKQNTFCP

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=393, Percent_Identity=28.2442748091603, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI169881279, Length=393, Percent_Identity=28.2442748091603, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI56713256, Length=400, Percent_Identity=29.25, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI56713254, Length=400, Percent_Identity=29.25, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI169881281, Length=300, Percent_Identity=27.3333333333333, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI4507369, Length=386, Percent_Identity=26.6839378238342, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI187936925, Length=401, Percent_Identity=21.6957605985037, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI14211921, Length=401, Percent_Identity=21.6957605985037, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI149944424, Length=392, Percent_Identity=24.234693877551, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI7705897, Length=417, Percent_Identity=24.4604316546763, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI33469970, Length=417, Percent_Identity=24.4604316546763, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI19263340, Length=368, Percent_Identity=22.8260869565217, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI215599424, Length=368, Percent_Identity=22.8260869565217, Blast_Score=76, Evalue=7e-14,
Organism=Escherichia coli, GI1786816, Length=361, Percent_Identity=27.9778393351801, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1788722, Length=370, Percent_Identity=28.3783783783784, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1788627, Length=368, Percent_Identity=26.3586956521739, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1787909, Length=346, Percent_Identity=24.5664739884393, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787710, Length=335, Percent_Identity=25.0746268656716, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1790797, Length=369, Percent_Identity=23.3062330623306, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788332, Length=221, Percent_Identity=23.9819004524887, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71994472, Length=379, Percent_Identity=32.4538258575198, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI71994476, Length=379, Percent_Identity=32.4538258575198, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17567369, Length=398, Percent_Identity=30.6532663316583, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17567663, Length=386, Percent_Identity=25.9067357512953, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71981209, Length=369, Percent_Identity=22.2222222222222, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=267, Percent_Identity=30.3370786516854, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6323118, Length=374, Percent_Identity=24.5989304812834, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320317, Length=351, Percent_Identity=22.5071225071225, Blast_Score=83, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6322075, Length=245, Percent_Identity=25.7142857142857, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28573069, Length=417, Percent_Identity=28.7769784172662, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24646114, Length=417, Percent_Identity=28.7769784172662, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI28573067, Length=417, Percent_Identity=28.7769784172662, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI28573065, Length=417, Percent_Identity=28.7769784172662, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI18859735, Length=389, Percent_Identity=25.706940874036, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI45551451, Length=397, Percent_Identity=24.1813602015113, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641770, Length=397, Percent_Identity=24.1813602015113, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641760, Length=397, Percent_Identity=24.1813602015113, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641768, Length=397, Percent_Identity=24.1813602015113, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641766, Length=397, Percent_Identity=24.1813602015113, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641764, Length=397, Percent_Identity=24.1813602015113, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.17

Molecular weight: Translated: 43686; Mature: 43686

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQFELSRAAESLQPSGIRKFFDLAAGMKGVISLGVGEPDFVTPWNVRKACIRSLEEGYT
CCCCHHHHHHHHCCCHHHHHHHHHHCCCHHEEEECCCCCCCCCCCHHHHHHHHHHHCCCE
AYTANAGLLELRQEIAKYLKKQFEVSYDPNDEIIVTVGASQALDVAMRAIVNPGDEVIII
EEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCEEEE
EPSFVSYAPLVTLAGGVPIPVATSLENAFKVQPEQIEAAITTKTKAILLCSPNNPTGALL
CCCHHHHHHHHHHCCCCCCCCHHCHHHHHCCCHHHHHHHEEECCEEEEEECCCCCCCCCC
NKSELEKLAEIVEKYNLIVLSDEIYAELVYDEAYTSFASIKNMRDHTILISGFSKGFAMT
CHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEC
GWRLGMIAAPTHFSSFMLKIHQYSMMCAPTMSQFAALEALRSGNDEVIRMRDSYKKRRNF
CEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEHHHHHHHHHH
MTQSLNEMGLTCHVPGGAFYVFPSISSTGLSSAAFAEQLLIEEKIAVVPGSVFGESGEGF
HHHHHHHCCCEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCE
IRCSYATSLEQLMEAMNRMKRFVENKKRTKQNTFCP
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKQFELSRAAESLQPSGIRKFFDLAAGMKGVISLGVGEPDFVTPWNVRKACIRSLEEGYT
CCCCHHHHHHHHCCCHHHHHHHHHHCCCHHEEEECCCCCCCCCCCHHHHHHHHHHHCCCE
AYTANAGLLELRQEIAKYLKKQFEVSYDPNDEIIVTVGASQALDVAMRAIVNPGDEVIII
EEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCEEEE
EPSFVSYAPLVTLAGGVPIPVATSLENAFKVQPEQIEAAITTKTKAILLCSPNNPTGALL
CCCHHHHHHHHHHCCCCCCCCHHCHHHHHCCCHHHHHHHEEECCEEEEEECCCCCCCCCC
NKSELEKLAEIVEKYNLIVLSDEIYAELVYDEAYTSFASIKNMRDHTILISGFSKGFAMT
CHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEC
GWRLGMIAAPTHFSSFMLKIHQYSMMCAPTMSQFAALEALRSGNDEVIRMRDSYKKRRNF
CEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEHHHHHHHHHH
MTQSLNEMGLTCHVPGGAFYVFPSISSTGLSSAAFAEQLLIEEKIAVVPGSVFGESGEGF
HHHHHHHCCCEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCE
IRCSYATSLEQLMEAMNRMKRFVENKKRTKQNTFCP
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-succinyl-L-2,6-diaminoheptanedioate; 2-oxoglutarate

Specific reaction: N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-succinyl-2-L-amino-6-oxoheptanedioate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]