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The map label for this gene is murC [H]

Identifier: 152977042

GI number: 152977042

Start: 3415926

End: 3417236

Strand: Reverse

Name: murC [H]

Synonym: Bcer98_3349

Alternate gene names: 152977042

Gene position: 3417236-3415926 (Counterclockwise)

Preceding gene: 152977043

Following gene: 152977041

Centisome position: 83.61

GC content: 35.77

Gene sequence:

>1311_bases
ATGACAGTTTACCATTTTGTAGGAATTAAAGGAACAGGAATGAGTTCATTAGCACAAATTCTTCATGACATGAAGAATAC
TGTTCAAGGTTCTGATTATGAAAAGCGTTTCTTCACACAAGTAGCATTGGAAAAGCGTGGTATTTCAATCCTTCCTTTTG
ATAAAAACAATATTAAAGAAGGACAAGTGATTATTGCAGGAAATGCATTTCCTGATACGCATGAAGAAATTATGGCAGCG
AAAGAATTAAATATTCCAGTCCATCGTTACCATCACTTTTTAGGAAACCTTATGAGTCAGTATACAAGTGTTGCTGTAAC
AGGTGCGCATGGAAAAACATCAACAACAGGTTTGTTAGCCCATGTCATGCAAGGTGCTAACCCGACATCTTATCTGATTG
GCGATGGAACGGGACATGGGGTAGAAAATAGTAAGTATTTTGCGTTTGAAGCTTGTGAATATCGTCGTCATTTCTTGTCT
TACTATCCAGACTATGCAATTATGACAAATATTGACTTTGATCATCCGGATTATTTTGCAGACATTAATGATGTATTTCA
TGCATTCCAAGAGATGGCACTTCAAGTGAAAAAGGGAATTATTGCATGTGGTGATGATGAAGAACTTCAAAAAATTCAAG
CGAAAGTACCTGTTATTTTCTATGGATTTGGTGAAGATAATGATTTCCAAGCTCGTAACATTCAAAAGAGAACAGACGGT
ACTGTATTTGACGTATTCGTTCGTAATACGTATTATGAAACATTTAAAATTACAGGATACGGAAATCATAGCGTATTAAA
TGCATTAGCAGTAATAGCGCTTTGCCATTATGAAAATATCGATGTCGAAGTTGTGAAACATCAATTAACAACATTTGAAG
GCGTAAAACGTCGCTTTAATGAAAAAACGGTGAGAGACCAAGTCATTATTGATGATTATGCACATCATCCGACAGAAATT
AATGCAACGATTGAAGCGGCTCATCAAAAGTATCCAGAGCGTGAAATTATCGCTATCTTCCAGCCGCATACATTTTCACG
TACAGAGACGTTTTTAGATGAGTTTGCAGAAAGCCTAAGTAAAGCTGATCAAGTCTATTTATGTGACATTTTTGGATCAG
CACGTGAAAACAAAGGTGAATTAACAATTGAAGATTTGCAAAAACGCATTGATGGTGCAGAATTAATTACAGATACAACA
ACAGATATACTGAAAAAACATAAAAACGGCGTTCTTATTTTTATGGGCGCAGGCGACATTCAAAAATTCGAAGCAGCTTA
TATAAAAGAAGTGCAAGTTGCTGAGAAGTAA

Upstream 100 bases:

>100_bases
TTATCGGAAATGTATGATGATTACCAAAATAAGAAAAGATTCATATACTGTCTTATAGATAGGCCGTTGTATTAGTTCGA
AATGTTGGAGGTTCTTTAAG

Downstream 100 bases:

>100_bases
AAAAAAGACGCATAGCGGTGGCTATGCGTCTTTTTTAGTGCGTGATTTGTAGTATATGTGGTGTCGAAAGATGTTGGGAA
GCCGATATCTCCTGTCAAAA

Product: UDP-N-acetylmuramate--L-alanine ligase

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MTVYHFVGIKGTGMSSLAQILHDMKNTVQGSDYEKRFFTQVALEKRGISILPFDKNNIKEGQVIIAGNAFPDTHEEIMAA
KELNIPVHRYHHFLGNLMSQYTSVAVTGAHGKTSTTGLLAHVMQGANPTSYLIGDGTGHGVENSKYFAFEACEYRRHFLS
YYPDYAIMTNIDFDHPDYFADINDVFHAFQEMALQVKKGIIACGDDEELQKIQAKVPVIFYGFGEDNDFQARNIQKRTDG
TVFDVFVRNTYYETFKITGYGNHSVLNALAVIALCHYENIDVEVVKHQLTTFEGVKRRFNEKTVRDQVIIDDYAHHPTEI
NATIEAAHQKYPEREIIAIFQPHTFSRTETFLDEFAESLSKADQVYLCDIFGSARENKGELTIEDLQKRIDGAELITDTT
TDILKKHKNGVLIFMGAGDIQKFEAAYIKEVQVAEK

Sequences:

>Translated_436_residues
MTVYHFVGIKGTGMSSLAQILHDMKNTVQGSDYEKRFFTQVALEKRGISILPFDKNNIKEGQVIIAGNAFPDTHEEIMAA
KELNIPVHRYHHFLGNLMSQYTSVAVTGAHGKTSTTGLLAHVMQGANPTSYLIGDGTGHGVENSKYFAFEACEYRRHFLS
YYPDYAIMTNIDFDHPDYFADINDVFHAFQEMALQVKKGIIACGDDEELQKIQAKVPVIFYGFGEDNDFQARNIQKRTDG
TVFDVFVRNTYYETFKITGYGNHSVLNALAVIALCHYENIDVEVVKHQLTTFEGVKRRFNEKTVRDQVIIDDYAHHPTEI
NATIEAAHQKYPEREIIAIFQPHTFSRTETFLDEFAESLSKADQVYLCDIFGSARENKGELTIEDLQKRIDGAELITDTT
TDILKKHKNGVLIFMGAGDIQKFEAAYIKEVQVAEK
>Mature_435_residues
TVYHFVGIKGTGMSSLAQILHDMKNTVQGSDYEKRFFTQVALEKRGISILPFDKNNIKEGQVIIAGNAFPDTHEEIMAAK
ELNIPVHRYHHFLGNLMSQYTSVAVTGAHGKTSTTGLLAHVMQGANPTSYLIGDGTGHGVENSKYFAFEACEYRRHFLSY
YPDYAIMTNIDFDHPDYFADINDVFHAFQEMALQVKKGIIACGDDEELQKIQAKVPVIFYGFGEDNDFQARNIQKRTDGT
VFDVFVRNTYYETFKITGYGNHSVLNALAVIALCHYENIDVEVVKHQLTTFEGVKRRFNEKTVRDQVIIDDYAHHPTEIN
ATIEAAHQKYPEREIIAIFQPHTFSRTETFLDEFAESLSKADQVYLCDIFGSARENKGELTIEDLQKRIDGAELITDTTT
DILKKHKNGVLIFMGAGDIQKFEAAYIKEVQVAEK

Specific function: Cell wall formation [H]

COG id: COG0773

COG function: function code M; UDP-N-acetylmuramate-alanine ligase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

Organism=Escherichia coli, GI1786279, Length=466, Percent_Identity=28.755364806867, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1790680, Length=399, Percent_Identity=27.5689223057644, Blast_Score=129, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.8 [H]

Molecular weight: Translated: 49373; Mature: 49242

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVYHFVGIKGTGMSSLAQILHDMKNTVQGSDYEKRFFTQVALEKRGISILPFDKNNIKE
CEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCC
GQVIIAGNAFPDTHEEIMAAKELNIPVHRYHHFLGNLMSQYTSVAVTGAHGKTSTTGLLA
CEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHH
HVMQGANPTSYLIGDGTGHGVENSKYFAFEACEYRRHFLSYYPDYAIMTNIDFDHPDYFA
HHHHCCCCCEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHCCCEEEEEECCCCCCHHHH
DINDVFHAFQEMALQVKKGIIACGDDEELQKIQAKVPVIFYGFGEDNDFQARNIQKRTDG
HHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCC
TVFDVFVRNTYYETFKITGYGNHSVLNALAVIALCHYENIDVEVVKHQLTTFEGVKRRFN
CEEEEEECCCEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
EKTVRDQVIIDDYAHHPTEINATIEAAHQKYPEREIIAIFQPHTFSRTETFLDEFAESLS
HHHHHHHEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
KADQVYLCDIFGSARENKGELTIEDLQKRIDGAELITDTTTDILKKHKNGVLIFMGAGDI
CCCEEEEEEECCCCCCCCCCEEHHHHHHHCCCHHHHHCCHHHHHHHCCCCEEEEEECCCH
QKFEAAYIKEVQVAEK
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TVYHFVGIKGTGMSSLAQILHDMKNTVQGSDYEKRFFTQVALEKRGISILPFDKNNIKE
EEEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCC
GQVIIAGNAFPDTHEEIMAAKELNIPVHRYHHFLGNLMSQYTSVAVTGAHGKTSTTGLLA
CEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHH
HVMQGANPTSYLIGDGTGHGVENSKYFAFEACEYRRHFLSYYPDYAIMTNIDFDHPDYFA
HHHHCCCCCEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHCCCEEEEEECCCCCCHHHH
DINDVFHAFQEMALQVKKGIIACGDDEELQKIQAKVPVIFYGFGEDNDFQARNIQKRTDG
HHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCC
TVFDVFVRNTYYETFKITGYGNHSVLNALAVIALCHYENIDVEVVKHQLTTFEGVKRRFN
CEEEEEECCCEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
EKTVRDQVIIDDYAHHPTEINATIEAAHQKYPEREIIAIFQPHTFSRTETFLDEFAESLS
HHHHHHHEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
KADQVYLCDIFGSARENKGELTIEDLQKRIDGAELITDTTTDILKKHKNGVLIFMGAGDI
CCCEEEEEEECCCCCCCCCCEEHHHHHHHCCCHHHHHCCHHHHHHHCCCCEEEEEECCCH
QKFEAAYIKEVQVAEK
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA