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The map label for this gene is ccpA [H]

Identifier: 152977035

GI number: 152977035

Start: 3409989

End: 3410987

Strand: Reverse

Name: ccpA [H]

Synonym: Bcer98_3342

Alternate gene names: 152977035

Gene position: 3410987-3409989 (Counterclockwise)

Preceding gene: 152977036

Following gene: 152977034

Centisome position: 83.46

GC content: 36.24

Gene sequence:

>999_bases
ATGAACGTAACAATCTATGATGTAGCGCGTGAAGCGAATGTTTCAATGGCAACTGTATCACGTGTTGTAAACGGTAATCC
AAATGTAAAGCCTACAACAAGAAAGAAAGTATTAGAAGCAATTGACCGCTTAGGATATCGTCCAAATGCGGTAGCGCGTG
GTTTAGCAAGTAAAAAAACAACTACAGTAGGGGTTATTATTCCTGATATCTCCAATACATTCTATGCAGAACTTGCACGT
GGGATTGAAGATATTGCAACAATGTACAAATATAATATTATTTTAAGTAACTCGGATCAAAATAAAGAAAAAGAGTTCCA
CTTATTAAATACAATGCTAGGTAAACAAGTAGATGGGATTGTATTCATGGGTGAGGATATTACAGATATTCATGTCGAAG
AATTTAAAAAATCTCCAGTACCGATTGTATTAGCGGCATCATTTGATGAGAAGAATGAAACGCCATCAGTAAATATTGAT
TATACACAAGCAGCTTATGATGCAATAAAGTATTTCTTAGAAAAAGGTCATAAGCGAATTGGTTTCGTATCAGGTCCTTT
CGTTGATAAGGCAGGAAGCGCAAAGAAATTACAAGGGTATAAAAAAGCTTTAGAGGAAACTGGTATTTCATATGATGAAA
AACTTGTAATTGATGGAGATTACACATATGATTCAGGTTTAGAAGCATTTGAAAAACTTTGGGCACTTGATCAAAAACCA
ACAGCAATTTTCGTGTCTTCCGATGAAATGGCATTAGGTGTCATCCATGCAGCACAAGACGCTGGCTTACGTGTACCAGA
AGATGTAGAAGTGCTTGGATTTGACAATACACGCCTTGCATTAATGGTGCGCCCACAGCTTTCAACAGTCGTACAACCAA
TGTATGACATCGGTGCAGTAGCGATGCGTTTACTTACAAAATATATGAATAAAGAAAAAGTAGAAGATCATACAGTTATC
TTACCTCATCGCATTCAATTTAGAAATTCGACGAAGTAA

Upstream 100 bases:

>100_bases
ACGATTGGTGGCATCTTCAAATAGAGTTGATGTCTTTTTTTCATTCAAGTGAACCGATACATAAAAATAGATAACATAGA
TAGAAGGAGTGTGCGAAAAG

Downstream 100 bases:

>100_bases
GGAAAAAAACTCACAGCGCGGCGCTGTGAGTTTTTTTGTTATCTCCGCCGATAAGGTGTCCGCCTTTAAACGAGAAGTTC
AACTGAGAATAGTGAAACAG

Product: global transcriptional regulator, catabolite control protein A

Products: NA

Alternate protein names: Glucose-resistance amylase regulator [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MNVTIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIDRLGYRPNAVARGLASKKTTTVGVIIPDISNTFYAELAR
GIEDIATMYKYNIILSNSDQNKEKEFHLLNTMLGKQVDGIVFMGEDITDIHVEEFKKSPVPIVLAASFDEKNETPSVNID
YTQAAYDAIKYFLEKGHKRIGFVSGPFVDKAGSAKKLQGYKKALEETGISYDEKLVIDGDYTYDSGLEAFEKLWALDQKP
TAIFVSSDEMALGVIHAAQDAGLRVPEDVEVLGFDNTRLALMVRPQLSTVVQPMYDIGAVAMRLLTKYMNKEKVEDHTVI
LPHRIQFRNSTK

Sequences:

>Translated_332_residues
MNVTIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIDRLGYRPNAVARGLASKKTTTVGVIIPDISNTFYAELAR
GIEDIATMYKYNIILSNSDQNKEKEFHLLNTMLGKQVDGIVFMGEDITDIHVEEFKKSPVPIVLAASFDEKNETPSVNID
YTQAAYDAIKYFLEKGHKRIGFVSGPFVDKAGSAKKLQGYKKALEETGISYDEKLVIDGDYTYDSGLEAFEKLWALDQKP
TAIFVSSDEMALGVIHAAQDAGLRVPEDVEVLGFDNTRLALMVRPQLSTVVQPMYDIGAVAMRLLTKYMNKEKVEDHTVI
LPHRIQFRNSTK
>Mature_332_residues
MNVTIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIDRLGYRPNAVARGLASKKTTTVGVIIPDISNTFYAELAR
GIEDIATMYKYNIILSNSDQNKEKEFHLLNTMLGKQVDGIVFMGEDITDIHVEEFKKSPVPIVLAASFDEKNETPSVNID
YTQAAYDAIKYFLEKGHKRIGFVSGPFVDKAGSAKKLQGYKKALEETGISYDEKLVIDGDYTYDSGLEAFEKLWALDQKP
TAIFVSSDEMALGVIHAAQDAGLRVPEDVEVLGFDNTRLALMVRPQLSTVVQPMYDIGAVAMRLLTKYMNKEKVEDHTVI
LPHRIQFRNSTK

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (AmyE) and the acetyl-coenzyme A synthetase (AcsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=330, Percent_Identity=37.5757575757576, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1787948, Length=330, Percent_Identity=34.5454545454545, Blast_Score=194, Evalue=5e-51,
Organism=Escherichia coli, GI1790194, Length=330, Percent_Identity=31.8181818181818, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1789068, Length=307, Percent_Identity=33.2247557003257, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI1789202, Length=291, Percent_Identity=31.6151202749141, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI1788474, Length=302, Percent_Identity=30.794701986755, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI1787580, Length=329, Percent_Identity=26.4437689969605, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI48994940, Length=304, Percent_Identity=25.6578947368421, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1786540, Length=334, Percent_Identity=28.1437125748503, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1790715, Length=333, Percent_Identity=24.3243243243243, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1789456, Length=353, Percent_Identity=27.4787535410765, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787906, Length=335, Percent_Identity=23.2835820895522, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786268, Length=314, Percent_Identity=25.4777070063694, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37006; Mature: 37006

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVTIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIDRLGYRPNAVARGLASKKT
CCEEEEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCC
TTVGVIIPDISNTFYAELARGIEDIATMYKYNIILSNSDQNKEKEFHLLNTMLGKQVDGI
EEEEEEECCCCHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHCCCCCCE
VFMGEDITDIHVEEFKKSPVPIVLAASFDEKNETPSVNIDYTQAAYDAIKYFLEKGHKRI
EEECCCCCCCCHHHHCCCCCCEEEEECCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCEE
GFVSGPFVDKAGSAKKLQGYKKALEETGISYDEKLVIDGDYTYDSGLEAFEKLWALDQKP
EEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCC
TAIFVSSDEMALGVIHAAQDAGLRVPEDVEVLGFDNTRLALMVRPQLSTVVQPMYDIGAV
CEEEEECCCEEEEEEEECCCCCCCCCCCCEEEECCCCEEEEEECCHHHHHHHHHHHHHHH
AMRLLTKYMNKEKVEDHTVILPHRIQFRNSTK
HHHHHHHHHCHHCCCCCEEEECCEEECCCCCC
>Mature Secondary Structure
MNVTIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIDRLGYRPNAVARGLASKKT
CCEEEEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCC
TTVGVIIPDISNTFYAELARGIEDIATMYKYNIILSNSDQNKEKEFHLLNTMLGKQVDGI
EEEEEEECCCCHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHCCCCCCE
VFMGEDITDIHVEEFKKSPVPIVLAASFDEKNETPSVNIDYTQAAYDAIKYFLEKGHKRI
EEECCCCCCCCHHHHCCCCCCEEEEECCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCEE
GFVSGPFVDKAGSAKKLQGYKKALEETGISYDEKLVIDGDYTYDSGLEAFEKLWALDQKP
EEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCC
TAIFVSSDEMALGVIHAAQDAGLRVPEDVEVLGFDNTRLALMVRPQLSTVVQPMYDIGAV
CEEEEECCCEEEEEEEECCCCCCCCCCCCEEEECCCCEEEEEECCHHHHHHHHHHHHHHH
AMRLLTKYMNKEKVEDHTVILPHRIQFRNSTK
HHHHHHHHHCHHCCCCCEEEECCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1904524; 9387221; 9384377 [H]