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The map label for this gene is argG [H]

Identifier: 152977001

GI number: 152977001

Start: 3375629

End: 3376834

Strand: Reverse

Name: argG [H]

Synonym: Bcer98_3306

Alternate gene names: 152977001

Gene position: 3376834-3375629 (Counterclockwise)

Preceding gene: 152977004

Following gene: 152977000

Centisome position: 82.62

GC content: 37.89

Gene sequence:

>1206_bases
ATGGAGAAGAAAAAAGTTGTGTTAGCATATTCTGGAGGCCTTGATACTTCTGTTGCAATTAAATGGTTGCAAGAAAAAAA
TTATGATGTTATCGCTCTTTGTTTAGATTTAGGAGAAGGGGAAGATTTAGAGTTTGTAAAAGAAAAGGCACTTTCAGTAG
GTGCGATTAAATCGTACATGATCGATGTGCAAGAAGAATTTATGAATGAATATGCATTGGTGGCTTTGCAAGGGCATACG
TTATATGAAGGGAAATATCCTCTTGTTTCTGCATTATCTCGTCCGCTAATTGCGAAAAAACTAGTTGAGATTGCAGAACT
AGAAGGTGCTAGTGCGGTTGCACACGGATGTACCGGTAAGGGGAATGACCAAGTTCGTTTTGAAGTATCGATTCAAGCAT
TAAACCCATATTTAGAAGTAATTGCGCCAGTGCGTGAATGGAAATGGTCACGTGAGGAAGAAATTGCGTATGCAAAAGAA
AACGATGTACCCATTCCCATTAATTTAGATAGCCCATTTTCTATTGACCAAAACTTATGGGGACGCAGTAATGAGTGCGG
AATTTTAGAAGATCCTTGGGCAGCGCCACCAGAAGATGCGTATGAAATGACTGTACCATTAGAAAATACACCAGATCAGC
CAGAATTTGTAGAAATCGGATTTGAAGAAGGTGTACCAACAACATTAAATGGAACAACTTACTCACTTTCACAATTAATG
AAAACGTTAAATTCACTTGCTGGAAAGCATGGAATTGGGCGTATCGATCATGTAGAAAACCGCCTTGTCGGTATTAAATC
GCGTGAGGTGTATGAATGCCCAGCGGCGATGACATTACTTACAGCTCATAAAGAACTTGAAGATTTAACACTTGTAAAAG
AAGTAGCTCACTTTAAACCGATGATGGAACAAAAACTAACAGAATTAATCTATAATGGCTTATGGTTCTCGCCTTTAAAA
CAAGCGCTTGTTGCTTTTTTACAAGAAACACAAAAAACAGTATCAGGTACAGTGCGTGTAAAATTATTTAAAGGGCACGC
GATTGTAGAAGGACGTAAATCAGAATATTCCTTATATGATGAGAATTTAGCGACTTATACAGTGAATGATGAATTTAACC
ACGATGCAGCAGTTGGTTTTATTTCACTATTTGGTCTTCCAACAAAGGTATATAGTCAAGTAAATCAGAAGAAGGTGGAA
GCGTGA

Upstream 100 bases:

>100_bases
GAGAATTTTTTTGAATATCTCTTGATTCATTTGAAAAAAGATGATAAAGTTTGGATTATTATAAGTAATCATGAATATTT
ATTCTTTTAGGGGGTATAAA

Downstream 100 bases:

>100_bases
GTAAGCTGTGGGGGGGACGCTTTACAGAAGAAGCAGAAGCATGGGTCGAGGAGTTTGGGGCATCCATCTCCTTTGACAAA
CAATTAGTGAAACAAGATAT

Product: argininosuccinate synthase

Products: NA

Alternate protein names: Citrulline--aspartate ligase [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MEKKKVVLAYSGGLDTSVAIKWLQEKNYDVIALCLDLGEGEDLEFVKEKALSVGAIKSYMIDVQEEFMNEYALVALQGHT
LYEGKYPLVSALSRPLIAKKLVEIAELEGASAVAHGCTGKGNDQVRFEVSIQALNPYLEVIAPVREWKWSREEEIAYAKE
NDVPIPINLDSPFSIDQNLWGRSNECGILEDPWAAPPEDAYEMTVPLENTPDQPEFVEIGFEEGVPTTLNGTTYSLSQLM
KTLNSLAGKHGIGRIDHVENRLVGIKSREVYECPAAMTLLTAHKELEDLTLVKEVAHFKPMMEQKLTELIYNGLWFSPLK
QALVAFLQETQKTVSGTVRVKLFKGHAIVEGRKSEYSLYDENLATYTVNDEFNHDAAVGFISLFGLPTKVYSQVNQKKVE
A

Sequences:

>Translated_401_residues
MEKKKVVLAYSGGLDTSVAIKWLQEKNYDVIALCLDLGEGEDLEFVKEKALSVGAIKSYMIDVQEEFMNEYALVALQGHT
LYEGKYPLVSALSRPLIAKKLVEIAELEGASAVAHGCTGKGNDQVRFEVSIQALNPYLEVIAPVREWKWSREEEIAYAKE
NDVPIPINLDSPFSIDQNLWGRSNECGILEDPWAAPPEDAYEMTVPLENTPDQPEFVEIGFEEGVPTTLNGTTYSLSQLM
KTLNSLAGKHGIGRIDHVENRLVGIKSREVYECPAAMTLLTAHKELEDLTLVKEVAHFKPMMEQKLTELIYNGLWFSPLK
QALVAFLQETQKTVSGTVRVKLFKGHAIVEGRKSEYSLYDENLATYTVNDEFNHDAAVGFISLFGLPTKVYSQVNQKKVE
A
>Mature_401_residues
MEKKKVVLAYSGGLDTSVAIKWLQEKNYDVIALCLDLGEGEDLEFVKEKALSVGAIKSYMIDVQEEFMNEYALVALQGHT
LYEGKYPLVSALSRPLIAKKLVEIAELEGASAVAHGCTGKGNDQVRFEVSIQALNPYLEVIAPVREWKWSREEEIAYAKE
NDVPIPINLDSPFSIDQNLWGRSNECGILEDPWAAPPEDAYEMTVPLENTPDQPEFVEIGFEEGVPTTLNGTTYSLSQLM
KTLNSLAGKHGIGRIDHVENRLVGIKSREVYECPAAMTLLTAHKELEDLTLVKEVAHFKPMMEQKLTELIYNGLWFSPLK
QALVAFLQETQKTVSGTVRVKLFKGHAIVEGRKSEYSLYDENLATYTVNDEFNHDAAVGFISLFGLPTKVYSQVNQKKVE
A

Specific function: Arginine biosynthesis; seventh step. [C]

COG id: COG0137

COG function: function code E; Argininosuccinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the argininosuccinate synthase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI53759107, Length=409, Percent_Identity=43.7652811735941, Blast_Score=313, Evalue=2e-85,
Organism=Homo sapiens, GI16950633, Length=409, Percent_Identity=43.7652811735941, Blast_Score=313, Evalue=2e-85,
Organism=Escherichia coli, GI1789563, Length=406, Percent_Identity=27.0935960591133, Blast_Score=119, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6324514, Length=416, Percent_Identity=39.1826923076923, Blast_Score=286, Evalue=5e-78,
Organism=Drosophila melanogaster, GI21358151, Length=397, Percent_Identity=40.8060453400504, Blast_Score=291, Evalue=5e-79,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001518
- InterPro:   IPR018223
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00764 Arginosuc_synth [H]

EC number: =6.3.4.5 [H]

Molecular weight: Translated: 44797; Mature: 44797

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00564 ARGININOSUCCIN_SYN_1 ; PS00565 ARGININOSUCCIN_SYN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKKKVVLAYSGGLDTSVAIKWLQEKNYDVIALCLDLGEGEDLEFVKEKALSVGAIKSYM
CCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
IDVQEEFMNEYALVALQGHTLYEGKYPLVSALSRPLIAKKLVEIAELEGASAVAHGCTGK
HHHHHHHCCCEEEEEEECCEEECCCCHHHHHHHCHHHHHHHHHHHHCCCCHHHHCCCCCC
GNDQVRFEVSIQALNPYLEVIAPVREWKWSREEEIAYAKENDVPIPINLDSPFSIDQNLW
CCCEEEEEEEEEHHHHHHHHHHHHHHHCCCCCHHCEEECCCCCEEEEECCCCCCCCHHHC
GRSNECGILEDPWAAPPEDAYEMTVPLENTPDQPEFVEIGFEEGVPTTLNGTTYSLSQLM
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCEECCCHHHHHHHH
KTLNSLAGKHGIGRIDHVENRLVGIKSREVYECPAAMTLLTAHKELEDLTLVKEVAHFKP
HHHHHHHCCCCCCCHHHHHHHEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MMEQKLTELIYNGLWFSPLKQALVAFLQETQKTVSGTVRVKLFKGHAIVEGRKSEYSLYD
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCEEECCCCCCCEEEC
ENLATYTVNDEFNHDAAVGFISLFGLPTKVYSQVNQKKVEA
CCEEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MEKKKVVLAYSGGLDTSVAIKWLQEKNYDVIALCLDLGEGEDLEFVKEKALSVGAIKSYM
CCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
IDVQEEFMNEYALVALQGHTLYEGKYPLVSALSRPLIAKKLVEIAELEGASAVAHGCTGK
HHHHHHHCCCEEEEEEECCEEECCCCHHHHHHHCHHHHHHHHHHHHCCCCHHHHCCCCCC
GNDQVRFEVSIQALNPYLEVIAPVREWKWSREEEIAYAKENDVPIPINLDSPFSIDQNLW
CCCEEEEEEEEEHHHHHHHHHHHHHHHCCCCCHHCEEECCCCCEEEEECCCCCCCCHHHC
GRSNECGILEDPWAAPPEDAYEMTVPLENTPDQPEFVEIGFEEGVPTTLNGTTYSLSQLM
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCEECCCHHHHHHHH
KTLNSLAGKHGIGRIDHVENRLVGIKSREVYECPAAMTLLTAHKELEDLTLVKEVAHFKP
HHHHHHHCCCCCCCHHHHHHHEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MMEQKLTELIYNGLWFSPLKQALVAFLQETQKTVSGTVRVKLFKGHAIVEGRKSEYSLYD
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCEEECCCCCCCEEEC
ENLATYTVNDEFNHDAAVGFISLFGLPTKVYSQVNQKKVEA
CCEEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA