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The map label for this gene is glcK [H]

Identifier: 152976696

GI number: 152976696

Start: 3039292

End: 3040275

Strand: Reverse

Name: glcK [H]

Synonym: Bcer98_2991

Alternate gene names: 152976696

Gene position: 3040275-3039292 (Counterclockwise)

Preceding gene: 152976697

Following gene: 152976694

Centisome position: 74.39

GC content: 40.24

Gene sequence:

>984_bases
ATGGAAGAGAAATGGTTAGTTGGTGTTGACCTGGGTGGGACGACAATTAAATTAGCATTTATTAATGTGTACGGTGAAAT
TTTACACAAGTGGGAAATCCCAACAGATACTAGTGAACAAGGAAAACATATTACACTAGATGTAGCCAAAGCAATCGATA
AAAAATTAGAAGAATTAGGCGAATTAAAGAGTAAATTAATTGGTATTGGTATGGGTGCTCCGGGTCCTGTCCATGTAGCT
ACAGGCATGATTTATGAAGCGGTTAACTTAGGGTGGAAAAACTATCCATTAAAAGATTTATTAGAAGTTGAAACAGGTTT
ACCTGTTGTTATTGATAACGATGCCAACTTAGCAGCATTTGGGGAAATGTGGAAGGGTGCTGGAGAAGGTGCGAAAGATC
TTGTTTGTATGACGCTTGGAACTGGTGTTGGTGGCGGTGTTATTACCAATGGTGAAATCGTTCATGGTGCAAGCGGTGCA
GCTGGTGAAATTGGCCATATTACAGTCGTTACAGAAAATGCATTTCCTTGTAATTGCGGGAAATCTGGTTGCTTAGAGAC
AGTGGCATCCGCAACAGGGATTGTTCGTGTTGCTATGCAAAAAATGCAAGAAACAGAGAAGGAAAGTATACTGCGTTCGA
TGTTGGCTGAAGAAGGCCGTATTACATCAAAAGATGTATTTGAAGCATTAGGACAAGGTGATGAATTAGCAGCTGAAGTA
GTAGAAAAAATCGCTTCTTATTTAGGATTAGCTGTAGCAAACCTTGCAAGTACATTAAACCCTGAAAAAATTGTAATTGG
TGGCGGCGTCTCTAAAGCAGGTGATGCGCTATTAGAACCAACGCAACGCTATTTTGAACAATACGCATTCTCACGTGCTA
GAAAGAGCACAAAGCTAGCAATTGCAACGCTTGGTAATGATGCGGGTGTAATTGGAGGAGCTTGGCTTGTAAAAAAGCAG
CAATACGAAGTGAAGATGATATAA

Upstream 100 bases:

>100_bases
AGCTGATTGAACGAAACGATTATCAAACAGCTTTATTTTTAATAAAGCAAGAAATTCAAAAAGAGATGAGCAAGAAATAG
AAAAAGGTAGGTTAGCAAAA

Downstream 100 bases:

>100_bases
TTTGTGAAGAATAAAAAACGAAAGGGCTGCCCCTTTCGTTTTTTATATGCAAAATCATGTTGAATAAGAATATAACAATG
AATTATGATGCTGGTGGATA

Product: ROK family glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MEEKWLVGVDLGGTTIKLAFINVYGEILHKWEIPTDTSEQGKHITLDVAKAIDKKLEELGELKSKLIGIGMGAPGPVHVA
TGMIYEAVNLGWKNYPLKDLLEVETGLPVVIDNDANLAAFGEMWKGAGEGAKDLVCMTLGTGVGGGVITNGEIVHGASGA
AGEIGHITVVTENAFPCNCGKSGCLETVASATGIVRVAMQKMQETEKESILRSMLAEEGRITSKDVFEALGQGDELAAEV
VEKIASYLGLAVANLASTLNPEKIVIGGGVSKAGDALLEPTQRYFEQYAFSRARKSTKLAIATLGNDAGVIGGAWLVKKQ
QYEVKMI

Sequences:

>Translated_327_residues
MEEKWLVGVDLGGTTIKLAFINVYGEILHKWEIPTDTSEQGKHITLDVAKAIDKKLEELGELKSKLIGIGMGAPGPVHVA
TGMIYEAVNLGWKNYPLKDLLEVETGLPVVIDNDANLAAFGEMWKGAGEGAKDLVCMTLGTGVGGGVITNGEIVHGASGA
AGEIGHITVVTENAFPCNCGKSGCLETVASATGIVRVAMQKMQETEKESILRSMLAEEGRITSKDVFEALGQGDELAAEV
VEKIASYLGLAVANLASTLNPEKIVIGGGVSKAGDALLEPTQRYFEQYAFSRARKSTKLAIATLGNDAGVIGGAWLVKKQ
QYEVKMI
>Mature_327_residues
MEEKWLVGVDLGGTTIKLAFINVYGEILHKWEIPTDTSEQGKHITLDVAKAIDKKLEELGELKSKLIGIGMGAPGPVHVA
TGMIYEAVNLGWKNYPLKDLLEVETGLPVVIDNDANLAAFGEMWKGAGEGAKDLVCMTLGTGVGGGVITNGEIVHGASGA
AGEIGHITVVTENAFPCNCGKSGCLETVASATGIVRVAMQKMQETEKESILRSMLAEEGRITSKDVFEALGQGDELAAEV
VEKIASYLGLAVANLASTLNPEKIVIGGGVSKAGDALLEPTQRYFEQYAFSRARKSTKLAIATLGNDAGVIGGAWLVKKQ
QYEVKMI

Specific function: May Be A Regulator In Specific Sugar Metabolism. May Influence The Rate Of Glucose Uptake Or Glycolysis In Cells In The Rich Medium. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=272, Percent_Identity=31.25, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI298566315, Length=272, Percent_Identity=31.25, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI190014632, Length=272, Percent_Identity=31.25, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI4885285, Length=272, Percent_Identity=31.25, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI1787878, Length=269, Percent_Identity=33.457249070632, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786891, Length=316, Percent_Identity=28.7974683544304, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI87081733, Length=327, Percent_Identity=30.2752293577982, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1787363, Length=319, Percent_Identity=26.9592476489028, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87082127, Length=289, Percent_Identity=25.6055363321799, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082230, Length=283, Percent_Identity=29.3286219081272, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790522, Length=293, Percent_Identity=26.6211604095563, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 34560; Mature: 34560

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEKWLVGVDLGGTTIKLAFINVYGEILHKWEIPTDTSEQGKHITLDVAKAIDKKLEELG
CCCCEEEEEECCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHH
ELKSKLIGIGMGAPGPVHVATGMIYEAVNLGWKNYPLKDLLEVETGLPVVIDNDANLAAF
HHHHHHEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEECCCCHHHH
GEMWKGAGEGAKDLVCMTLGTGVGGGVITNGEIVHGASGAAGEIGHITVVTENAFPCNCG
HHHHHCCCCCCHHEEEEEECCCCCCCEEECCEEEECCCCCCCCCEEEEEEECCCCCCCCC
KSGCLETVASATGIVRVAMQKMQETEKESILRSMLAEEGRITSKDVFEALGQGDELAAEV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHH
VEKIASYLGLAVANLASTLNPEKIVIGGGVSKAGDALLEPTQRYFEQYAFSRARKSTKLA
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHCHHHHHHHHHHHHHHHHHHHHCCCEEE
IATLGNDAGVIGGAWLVKKQQYEVKMI
EEEECCCCCEECCCEEEEECCEEEECC
>Mature Secondary Structure
MEEKWLVGVDLGGTTIKLAFINVYGEILHKWEIPTDTSEQGKHITLDVAKAIDKKLEELG
CCCCEEEEEECCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHH
ELKSKLIGIGMGAPGPVHVATGMIYEAVNLGWKNYPLKDLLEVETGLPVVIDNDANLAAF
HHHHHHEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEECCCCHHHH
GEMWKGAGEGAKDLVCMTLGTGVGGGVITNGEIVHGASGAAGEIGHITVVTENAFPCNCG
HHHHHCCCCCCHHEEEEEECCCCCCCEEECCEEEECCCCCCCCCEEEEEEECCCCCCCCC
KSGCLETVASATGIVRVAMQKMQETEKESILRSMLAEEGRITSKDVFEALGQGDELAAEV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHH
VEKIASYLGLAVANLASTLNPEKIVIGGGVSKAGDALLEPTQRYFEQYAFSRARKSTKLA
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHCHHHHHHHHHHHHHHHHHHHHCCCEEE
IATLGNDAGVIGGAWLVKKQQYEVKMI
EEEECCCCCEECCCEEEEECCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]