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The map label for this gene is aroK

Identifier: 152976631

GI number: 152976631

Start: 2983423

End: 2983920

Strand: Reverse

Name: aroK

Synonym: Bcer98_2922

Alternate gene names: 152976631

Gene position: 2983920-2983423 (Counterclockwise)

Preceding gene: 152976632

Following gene: 152976630

Centisome position: 73.01

GC content: 38.96

Gene sequence:

>498_bases
ATGAGAGCTATTTATATAACGGGGTATATGGGAGCAGGTAAAACGACAATTGGCAAGGCATTAAGTAAAGAGCTTGGTAT
TGACGTCATAGATACAGATCAGAAAATTGAAGAGAAGCAAGGGCGAGTGATTCGTGATATTTTTGCAAAAGAAGGAGAGC
GTTCATTTCGGCAATATGAAAGTGAGATGCTTTGCTCATTACCAACGAAGGATGTAATTATTACAACAGGCGGTGGTATT
GTTGAGCGCATAGAGAATCGCGAGTGGATGAAAGAGAATGGAACAGTTGTATATTTATATTGTGATCCTTATGTAATTGC
AGATCGGCTGCATGAAGATATAACGCGCCCGCTATTTCAAAAGGAGAATGTCGAAGCTTTTGTAGCGAAGTTTGAAGAAC
GTCGTGCTTTTTATGAAGAGGCAGTGATACAGATTGATACGACAAATAAAAGTATACAAGAGGTTACGGAAGAAATTCTT
CGTCGGATTAATTCATGA

Upstream 100 bases:

>100_bases
TTCCGTTATTTTAGATCAGAAATCTATATCACAAGCAGAATCTTTCGTTATAATACAAATAAAACTTTGGGCACGATTGA
ATAGAAAAGAGGATATGAAC

Downstream 100 bases:

>100_bases
AAAAGTGGGTACACTATTCAAGTAGAGGTGATAAAAACATGTCTACTAATGATTATGTGCGTTTTGTAACGCAACAATTT
GTATCTTATATGGATGATCC

Product: shikimate kinase

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MRAIYITGYMGAGKTTIGKALSKELGIDVIDTDQKIEEKQGRVIRDIFAKEGERSFRQYESEMLCSLPTKDVIITTGGGI
VERIENREWMKENGTVVYLYCDPYVIADRLHEDITRPLFQKENVEAFVAKFEERRAFYEEAVIQIDTTNKSIQEVTEEIL
RRINS

Sequences:

>Translated_165_residues
MRAIYITGYMGAGKTTIGKALSKELGIDVIDTDQKIEEKQGRVIRDIFAKEGERSFRQYESEMLCSLPTKDVIITTGGGI
VERIENREWMKENGTVVYLYCDPYVIADRLHEDITRPLFQKENVEAFVAKFEERRAFYEEAVIQIDTTNKSIQEVTEEIL
RRINS
>Mature_165_residues
MRAIYITGYMGAGKTTIGKALSKELGIDVIDTDQKIEEKQGRVIRDIFAKEGERSFRQYESEMLCSLPTKDVIITTGGGI
VERIENREWMKENGTVVYLYCDPYVIADRLHEDITRPLFQKENVEAFVAKFEERRAFYEEAVIQIDTTNKSIQEVTEEIL
RRINS

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family

Homologues:

Organism=Escherichia coli, GI87082255, Length=168, Percent_Identity=35.7142857142857, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1786587, Length=161, Percent_Identity=35.4037267080745, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): AROK_BACCN (A7GSP5)

Other databases:

- EMBL:   CP000764
- RefSeq:   YP_001376148.1
- ProteinModelPortal:   A7GSP5
- SMR:   A7GSP5
- STRING:   A7GSP5
- EnsemblBacteria:   EBBACT00000036994
- GeneID:   5346930
- GenomeReviews:   CP000764_GR
- KEGG:   bcy:Bcer98_2922
- eggNOG:   COG0703
- GeneTree:   EBGT00050000003023
- HOGENOM:   HBG335815
- OMA:   VEKEGWE
- ProtClustDB:   PRK00131
- BioCyc:   BCER315749:BCER98_2922-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00109
- InterPro:   IPR000623
- PRINTS:   PR01100

Pfam domain/function: PF01202 SKI

EC number: =2.7.1.71

Molecular weight: Translated: 19065; Mature: 19065

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: BINDING 33-33 BINDING 57-57 BINDING 78-78 BINDING 116-116 BINDING 134-134

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAIYITGYMGAGKTTIGKALSKELGIDVIDTDQKIEEKQGRVIRDIFAKEGERSFRQYE
CEEEEEEEECCCCHHHHHHHHHHHHCCEEECCCHHHHHHHCHHHHHHHHCCCHHHHHHHH
SEMLCSLPTKDVIITTGGGIVERIENREWMKENGTVVYLYCDPYVIADRLHEDITRPLFQ
HHHHHCCCCCCEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHH
KENVEAFVAKFEERRAFYEEAVIQIDTTNKSIQEVTEEILRRINS
HCCHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRAIYITGYMGAGKTTIGKALSKELGIDVIDTDQKIEEKQGRVIRDIFAKEGERSFRQYE
CEEEEEEEECCCCHHHHHHHHHHHHCCEEECCCHHHHHHHCHHHHHHHHCCCHHHHHHHH
SEMLCSLPTKDVIITTGGGIVERIENREWMKENGTVVYLYCDPYVIADRLHEDITRPLFQ
HHHHHCCCCCCEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHH
KENVEAFVAKFEERRAFYEEAVIQIDTTNKSIQEVTEEILRRINS
HCCHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA