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The map label for this gene is gcvT [H]

Identifier: 152976624

GI number: 152976624

Start: 2977677

End: 2978777

Strand: Reverse

Name: gcvT [H]

Synonym: Bcer98_2915

Alternate gene names: 152976624

Gene position: 2978777-2977677 (Counterclockwise)

Preceding gene: 152976627

Following gene: 152976623

Centisome position: 72.88

GC content: 36.97

Gene sequence:

>1101_bases
ATGATTACATTACAACGTACACCGCTATTTGATGTATATGCGAAGTATGGTGGGAAAACAATCGACTTTGGTGGTTGGGA
ATTACCAGTTCAATTTTCAAGCATTAAAGAAGAGCATGAAGCTGTTCGTACAGCAGCAGGCCTTTTTGATGTATCTCACA
TGGGAGAAGTAGAAGTAACAGGTGCAGATAGTTTAGCATTTTTACAACGCGTTGTTACAAATGACGTCTCTACCTTAAAG
GTAGGAGGCGCGCAATATACAGCAATGTGTTACGAAAATGGTGGTACTGTAGATGATTTATTAATCTACAAACGTGGTGA
AGAAGACTACTTATTAGTAATCAATGCATCGAATATCGAGAAAGATTACGAATGGTTAGCAAGTCATGTCATTGGCGATA
CGAAAGTGGTCAATGTTTCTAATGAAATTGCACAACTTGCAATTCAAGGACCAAAAGCAGAAGGCATTTTACAAAAAGTT
GTGTCAGAAGATTTAAAAGAAATTAAGTTCTTTAAATTTAAAAATGATGTTCTTGTAGATGGCATTCCAGCACTTGTATC
TCGCACAGGGTATACAGGAGAAGATGGATTTGAAATTTACTGTAAGAGTGAAGATGCTATAAAAATTTGGGAGAAACTTC
TTGAAGTTGGAGAAGAAGACAGCTTAAAGCCATGTGGTTTAGGAGCTCGTGATACGCTTCGCTTTGAAGCAACGCTTCCG
CTTTATGGCCAAGAATTATCAAAAGATATTACACCGATTGAAGCTGGAATTGGCTTTGCTGTCAAAACGAATAAAGAGGC
AGATTTCTTTGGAAAAGAAGTATTAAAAGAATATAAAGAAAACGGTGCACCTCGTAAATTAGTTGGCATCGAAGTAATTG
AACGCGGTATTCCGCGTACGCATTACCCTGTGTATGTAGGAGAAGAAAAAATTGGGGAAGTAACAAGTGGTACACAATCT
CCAACGTTAAAAAAAAGCATCGGTTTGGCATTAATTGATGTAAAATATGCAGCAATTGATACAGAAGTAGAAATTGAAAT
TCGAAAAAAACGCGTGAAAGCAGTAGTTGTTCCAACACCATTTTATAAACGTTCAAAGTAA

Upstream 100 bases:

>100_bases
TTGAGATTCCGTATATCCCATCTTTTCAAAATAAAAAATGTTTAGATAAGGGAAGCCAACTTTTATTGATTTGTCATAGA
CAGCATAAGGGGGAAGGAAC

Downstream 100 bases:

>100_bases
CCTGGAGAGGGGTAGATTTCATGTTGCATCGTTATCTTCCAATGACAGAAGAAGACAAAAAAGAAATGTTAGAAACGATC
GGTGTTCAAACCATTGATGA

Product: glycine cleavage system aminomethyltransferase T

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MITLQRTPLFDVYAKYGGKTIDFGGWELPVQFSSIKEEHEAVRTAAGLFDVSHMGEVEVTGADSLAFLQRVVTNDVSTLK
VGGAQYTAMCYENGGTVDDLLIYKRGEEDYLLVINASNIEKDYEWLASHVIGDTKVVNVSNEIAQLAIQGPKAEGILQKV
VSEDLKEIKFFKFKNDVLVDGIPALVSRTGYTGEDGFEIYCKSEDAIKIWEKLLEVGEEDSLKPCGLGARDTLRFEATLP
LYGQELSKDITPIEAGIGFAVKTNKEADFFGKEVLKEYKENGAPRKLVGIEVIERGIPRTHYPVYVGEEKIGEVTSGTQS
PTLKKSIGLALIDVKYAAIDTEVEIEIRKKRVKAVVVPTPFYKRSK

Sequences:

>Translated_366_residues
MITLQRTPLFDVYAKYGGKTIDFGGWELPVQFSSIKEEHEAVRTAAGLFDVSHMGEVEVTGADSLAFLQRVVTNDVSTLK
VGGAQYTAMCYENGGTVDDLLIYKRGEEDYLLVINASNIEKDYEWLASHVIGDTKVVNVSNEIAQLAIQGPKAEGILQKV
VSEDLKEIKFFKFKNDVLVDGIPALVSRTGYTGEDGFEIYCKSEDAIKIWEKLLEVGEEDSLKPCGLGARDTLRFEATLP
LYGQELSKDITPIEAGIGFAVKTNKEADFFGKEVLKEYKENGAPRKLVGIEVIERGIPRTHYPVYVGEEKIGEVTSGTQS
PTLKKSIGLALIDVKYAAIDTEVEIEIRKKRVKAVVVPTPFYKRSK
>Mature_366_residues
MITLQRTPLFDVYAKYGGKTIDFGGWELPVQFSSIKEEHEAVRTAAGLFDVSHMGEVEVTGADSLAFLQRVVTNDVSTLK
VGGAQYTAMCYENGGTVDDLLIYKRGEEDYLLVINASNIEKDYEWLASHVIGDTKVVNVSNEIAQLAIQGPKAEGILQKV
VSEDLKEIKFFKFKNDVLVDGIPALVSRTGYTGEDGFEIYCKSEDAIKIWEKLLEVGEEDSLKPCGLGARDTLRFEATLP
LYGQELSKDITPIEAGIGFAVKTNKEADFFGKEVLKEYKENGAPRKLVGIEVIERGIPRTHYPVYVGEEKIGEVTSGTQS
PTLKKSIGLALIDVKYAAIDTEVEIEIRKKRVKAVVVPTPFYKRSK

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: COG0404

COG function: function code E; Glycine cleavage system T protein (aminomethyltransferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI44662838, Length=371, Percent_Identity=34.5013477088949, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI257796258, Length=357, Percent_Identity=33.8935574229692, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI24797151, Length=336, Percent_Identity=29.1666666666667, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI257796254, Length=364, Percent_Identity=32.6923076923077, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI257796256, Length=319, Percent_Identity=32.2884012539185, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI197927446, Length=308, Percent_Identity=25.974025974026, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI21361378, Length=308, Percent_Identity=25.974025974026, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI194306651, Length=317, Percent_Identity=25.2365930599369, Blast_Score=109, Evalue=5e-24,
Organism=Escherichia coli, GI1789272, Length=373, Percent_Identity=36.4611260053619, Blast_Score=237, Evalue=9e-64,
Organism=Caenorhabditis elegans, GI17560118, Length=372, Percent_Identity=37.6344086021505, Blast_Score=216, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI32563613, Length=343, Percent_Identity=27.1137026239067, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71994045, Length=374, Percent_Identity=24.8663101604278, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71994052, Length=374, Percent_Identity=24.8663101604278, Blast_Score=110, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320222, Length=390, Percent_Identity=33.3333333333333, Blast_Score=200, Evalue=3e-52,
Organism=Drosophila melanogaster, GI20129441, Length=375, Percent_Identity=35.2, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI28571104, Length=272, Percent_Identity=28.6764705882353, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI20130091, Length=373, Percent_Identity=23.5924932975871, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 40518; Mature: 40518

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLQRTPLFDVYAKYGGKTIDFGGWELPVQFSSIKEEHEAVRTAAGLFDVSHMGEVEVT
CEEECCCCHHHHHHHHCCCEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
GADSLAFLQRVVTNDVSTLKVGGAQYTAMCYENGGTVDDLLIYKRGEEDYLLVINASNIE
CCHHHHHHHHHHHCCCCEEEECCCEEEEEEECCCCCEEEEEEEEECCCCEEEEEECCCCC
KDYEWLASHVIGDTKVVNVSNEIAQLAIQGPKAEGILQKVVSEDLKEIKFFKFKNDVLVD
HHHHHHHHHHCCCEEEEECCHHHHHHEECCCCHHHHHHHHHHHHHHHHHEEEECCCEEEC
GIPALVSRTGYTGEDGFEIYCKSEDAIKIWEKLLEVGEEDSLKPCGLGARDTLRFEATLP
CHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECC
LYGQELSKDITPIEAGIGFAVKTNKEADFFGKEVLKEYKENGAPRKLVGIEVIERGIPRT
CCHHHHHCCCCCHHHCCCEEEECCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHCCCCCC
HYPVYVGEEKIGEVTSGTQSPTLKKSIGLALIDVKYAAIDTEVEIEIRKKRVKAVVVPTP
CCCEEECHHHHCCCCCCCCCCCHHHHCCEEEEEEEEEEECCEEEEEEEECEEEEEEECCC
FYKRSK
CCCCCC
>Mature Secondary Structure
MITLQRTPLFDVYAKYGGKTIDFGGWELPVQFSSIKEEHEAVRTAAGLFDVSHMGEVEVT
CEEECCCCHHHHHHHHCCCEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
GADSLAFLQRVVTNDVSTLKVGGAQYTAMCYENGGTVDDLLIYKRGEEDYLLVINASNIE
CCHHHHHHHHHHHCCCCEEEECCCEEEEEEECCCCCEEEEEEEEECCCCEEEEEECCCCC
KDYEWLASHVIGDTKVVNVSNEIAQLAIQGPKAEGILQKVVSEDLKEIKFFKFKNDVLVD
HHHHHHHHHHCCCEEEEECCHHHHHHEECCCCHHHHHHHHHHHHHHHHHEEEECCCEEEC
GIPALVSRTGYTGEDGFEIYCKSEDAIKIWEKLLEVGEEDSLKPCGLGARDTLRFEATLP
CHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECC
LYGQELSKDITPIEAGIGFAVKTNKEADFFGKEVLKEYKENGAPRKLVGIEVIERGIPRT
CCHHHHHCCCCCHHHCCCEEEECCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHCCCCCC
HYPVYVGEEKIGEVTSGTQSPTLKKSIGLALIDVKYAAIDTEVEIEIRKKRVKAVVVPTP
CCCEEECHHHHCCCCCCCCCCCHHHHCCEEEEEEEEEEECCEEEEEEEECEEEEEEECCC
FYKRSK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA