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The map label for this gene is bioD [H]

Identifier: 152976528

GI number: 152976528

Start: 2892155

End: 2892883

Strand: Reverse

Name: bioD [H]

Synonym: Bcer98_2817

Alternate gene names: 152976528

Gene position: 2892883-2892155 (Counterclockwise)

Preceding gene: 152976529

Following gene: 152976527

Centisome position: 70.78

GC content: 39.23

Gene sequence:

>729_bases
ATGAGTGGCTTTTTTATTACAGCAACGGATACCGAAGTAGGAAAAACAGTTGTTACAGGTGCAATAGCGGGGGGACTTAG
AAAGCTTGGACATCATATAGGAGTATATAAACCGTTGCAAAGTGGTCATAGCGCTTCTCACCCAGAAGGTGATGCAGCTA
GATTAAAGATGGCATCAGGAGTAGAAACAGCAGTGGATAAAATTTGTCCGTATTCGGTTGAAGAACCGCTTGCTCCAAGA
TTGGCAATGCAGCGTGCAGGAAGAACGGTAACATTGGCGGATATTACTTCTTATTATAATGAGCTAATGGCAGAGTTTGA
TAGTTTATTAGTAGAAGGGGCAGGGGGACTTGCTGTTCCTTATACAGAAGATGCACTCGTTGTTGATTTTGCTAAGCAAT
TAAAATTACCGCTTATCATTGTTGCGCGTCCCACATTAGGTACTGTCAATCATACTGTTTTAACAATCTCATATGCGAAA
GCAAAAGGTTTGCAAGTTGCAGGTGTTATTTTATCGGGCTGTAAAGAAGATGAGAAAGAACGTGTACAAGAAAATAAAAA
AATGATTGAAGAGTTAAGTGATGTGCCAGTTTTCGGTTTATTTCCAAAGATTCGGGAAGAATATACGCGCGATGAACTAA
TAAAAGCAGCAGAAGAGAGTATTCAGATTTCATATTTAGAGGAGTATATGAAAAATGGAACAAGCATGGAATTTACACTT
TTACGCTAG

Upstream 100 bases:

>100_bases
CAATTGTATTCATGCCTCCGTTAGCATCTCAAATAGATGAACTAGATGAAATGTTACGCATTTTATATCAAGCAATTGCA
GATATTACGGAGGGGAAATC

Downstream 100 bases:

>100_bases
TTTAAATCGTCTAAAAGAAAAGTCACAATACCGTGAAGTAGTGGTAACGAATCAAGCTGAAGAACCGTGGCTGATTCGGA
ACGGAGCGCGTATGCTGAAT

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MSGFFITATDTEVGKTVVTGAIAGGLRKLGHHIGVYKPLQSGHSASHPEGDAARLKMASGVETAVDKICPYSVEEPLAPR
LAMQRAGRTVTLADITSYYNELMAEFDSLLVEGAGGLAVPYTEDALVVDFAKQLKLPLIIVARPTLGTVNHTVLTISYAK
AKGLQVAGVILSGCKEDEKERVQENKKMIEELSDVPVFGLFPKIREEYTRDELIKAAEESIQISYLEEYMKNGTSMEFTL
LR

Sequences:

>Translated_242_residues
MSGFFITATDTEVGKTVVTGAIAGGLRKLGHHIGVYKPLQSGHSASHPEGDAARLKMASGVETAVDKICPYSVEEPLAPR
LAMQRAGRTVTLADITSYYNELMAEFDSLLVEGAGGLAVPYTEDALVVDFAKQLKLPLIIVARPTLGTVNHTVLTISYAK
AKGLQVAGVILSGCKEDEKERVQENKKMIEELSDVPVFGLFPKIREEYTRDELIKAAEESIQISYLEEYMKNGTSMEFTL
LR
>Mature_241_residues
SGFFITATDTEVGKTVVTGAIAGGLRKLGHHIGVYKPLQSGHSASHPEGDAARLKMASGVETAVDKICPYSVEEPLAPRL
AMQRAGRTVTLADITSYYNELMAEFDSLLVEGAGGLAVPYTEDALVVDFAKQLKLPLIIVARPTLGTVNHTVLTISYAKA
KGLQVAGVILSGCKEDEKERVQENKKMIEELSDVPVFGLFPKIREEYTRDELIKAAEESIQISYLEEYMKNGTSMEFTLL
R

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=208, Percent_Identity=31.7307692307692, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI87081944, Length=174, Percent_Identity=30.4597701149425, Blast_Score=65, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324385, Length=197, Percent_Identity=33.502538071066, Blast_Score=75, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 26367; Mature: 26235

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGFFITATDTEVGKTVVTGAIAGGLRKLGHHIGVYKPLQSGHSASHPEGDAARLKMASG
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCHHHHHHHCC
VETAVDKICPYSVEEPLAPRLAMQRAGRTVTLADITSYYNELMAEFDSLLVEGAGGLAVP
HHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCEECC
YTEDALVVDFAKQLKLPLIIVARPTLGTVNHTVLTISYAKAKGLQVAGVILSGCKEDEKE
CCCCHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCHHHH
RVQENKKMIEELSDVPVFGLFPKIREEYTRDELIKAAEESIQISYLEEYMKNGTSMEFTL
HHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
LR
EC
>Mature Secondary Structure 
SGFFITATDTEVGKTVVTGAIAGGLRKLGHHIGVYKPLQSGHSASHPEGDAARLKMASG
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCHHHHHHHCC
VETAVDKICPYSVEEPLAPRLAMQRAGRTVTLADITSYYNELMAEFDSLLVEGAGGLAVP
HHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCEECC
YTEDALVVDFAKQLKLPLIIVARPTLGTVNHTVLTISYAKAKGLQVAGVILSGCKEDEKE
CCCCHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCHHHH
RVQENKKMIEELSDVPVFGLFPKIREEYTRDELIKAAEESIQISYLEEYMKNGTSMEFTL
HHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
LR
EC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA