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The map label for this gene is xerD [H]

Identifier: 152976499

GI number: 152976499

Start: 2868906

End: 2869796

Strand: Reverse

Name: xerD [H]

Synonym: Bcer98_2788

Alternate gene names: 152976499

Gene position: 2869796-2868906 (Counterclockwise)

Preceding gene: 152976500

Following gene: 152976498

Centisome position: 70.22

GC content: 35.58

Gene sequence:

>891_bases
TTGGAAGATCAATTAAAAGATTTTATTCATTATATGGTTGTGGAAAAAGGATTGGCCAAAAATACGGTTGTATCTTATGA
AAGAGATTTAAAAAGTTATGTAAAGTATTTGCAAAAGGTGGAACAAATGAAAACTTTTCATGAAGTGACTCGTATGCAAA
TCGTTAACTTTTTGCAGCATTTAAGAGAGAATGGAAAATCTTCAAAAACATTAGCGCGTCATATTGCATCGATTCGTTCA
TTTCATCAATTTTTACTTCGTGAACGAGCTGTAGAACATGATCCGTCAGTACATATTGAAACACCACAAGGGGAGCGAAA
ACTGCCGAAAGTTTTATCGGTAAGTGAGGTTGAAGCATTATTACAAACACCAAAGACGACGAGTGCTTACGGTATTCGAG
ATAAAGCAATGTTGGAGTTATTGTATGCAACAGGACTGCGTGTTTCGGAATTAATTGCACTCAACTTAGAGGATGTTCAT
TTAACAATGGGCTTTGTTCGCTGCGTCGGAAAAGGAAATAAGGAAAGAATTATTCCACTTGGAAGTTTAGCTACAGAAGC
AATTCAGCGTTATATTGAAAAAGGAAGAAAAGAATTGATGGGAAAAAAGGCAGTGGATGCATTATTTTTAAATCACCACG
GTAATCGATTATCTCGTCAAGGCTTTTGGAAGATTTTAAAACGTTTAGCAAAAGAAGCAAATATTGAGAAAGAGCTTACA
CCACATACATTGCGCCATTCTTTTGCTACACACCTGTTAGAAAATGGAGCAGACTTACGTGCTGTACAGGAAATGTTAGG
ACATGCAGATATTTCTACAACACAAATTTATACACATGTTTCAAAAACGAGATTAAAAGACGTATATAAGCAGTTTCACC
CAAGAGCATAA

Upstream 100 bases:

>100_bases
AGAAGAGACAGTAGAAAAAGTATCAGGGAATGAGGAACCAGCAAAAGATGCTTTCGTAAATAGAATGATTTTTTTCTATG
AAAATGGGGAGTAGTGTAGA

Downstream 100 bases:

>100_bases
GATGACTTATGCTCTTTTTCGTGCCATTTCGAATCAAAACGCTTTTAAGTAGGCAGAAAGTTCCATATGGAATTTTACAA
GCATTGTTTGTACGGTTGTT

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MEDQLKDFIHYMVVEKGLAKNTVVSYERDLKSYVKYLQKVEQMKTFHEVTRMQIVNFLQHLRENGKSSKTLARHIASIRS
FHQFLLRERAVEHDPSVHIETPQGERKLPKVLSVSEVEALLQTPKTTSAYGIRDKAMLELLYATGLRVSELIALNLEDVH
LTMGFVRCVGKGNKERIIPLGSLATEAIQRYIEKGRKELMGKKAVDALFLNHHGNRLSRQGFWKILKRLAKEANIEKELT
PHTLRHSFATHLLENGADLRAVQEMLGHADISTTQIYTHVSKTRLKDVYKQFHPRA

Sequences:

>Translated_296_residues
MEDQLKDFIHYMVVEKGLAKNTVVSYERDLKSYVKYLQKVEQMKTFHEVTRMQIVNFLQHLRENGKSSKTLARHIASIRS
FHQFLLRERAVEHDPSVHIETPQGERKLPKVLSVSEVEALLQTPKTTSAYGIRDKAMLELLYATGLRVSELIALNLEDVH
LTMGFVRCVGKGNKERIIPLGSLATEAIQRYIEKGRKELMGKKAVDALFLNHHGNRLSRQGFWKILKRLAKEANIEKELT
PHTLRHSFATHLLENGADLRAVQEMLGHADISTTQIYTHVSKTRLKDVYKQFHPRA
>Mature_296_residues
MEDQLKDFIHYMVVEKGLAKNTVVSYERDLKSYVKYLQKVEQMKTFHEVTRMQIVNFLQHLRENGKSSKTLARHIASIRS
FHQFLLRERAVEHDPSVHIETPQGERKLPKVLSVSEVEALLQTPKTTSAYGIRDKAMLELLYATGLRVSELIALNLEDVH
LTMGFVRCVGKGNKERIIPLGSLATEAIQRYIEKGRKELMGKKAVDALFLNHHGNRLSRQGFWKILKRLAKEANIEKELT
PHTLRHSFATHLLENGADLRAVQEMLGHADISTTQIYTHVSKTRLKDVYKQFHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=294, Percent_Identity=44.8979591836735, Blast_Score=258, Evalue=2e-70,
Organism=Escherichia coli, GI1790244, Length=289, Percent_Identity=35.2941176470588, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1790768, Length=183, Percent_Identity=32.7868852459016, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1790767, Length=193, Percent_Identity=27.4611398963731, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34070; Mature: 34070

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDQLKDFIHYMVVEKGLAKNTVVSYERDLKSYVKYLQKVEQMKTFHEVTRMQIVNFLQH
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRENGKSSKTLARHIASIRSFHQFLLRERAVEHDPSVHIETPQGERKLPKVLSVSEVEAL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHH
LQTPKTTSAYGIRDKAMLELLYATGLRVSELIALNLEDVHLTMGFVRCVGKGNKERIIPL
HHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCEEEH
GSLATEAIQRYIEKGRKELMGKKAVDALFLNHHGNRLSRQGFWKILKRLAKEANIEKELT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
PHTLRHSFATHLLENGADLRAVQEMLGHADISTTQIYTHVSKTRLKDVYKQFHPRA
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEDQLKDFIHYMVVEKGLAKNTVVSYERDLKSYVKYLQKVEQMKTFHEVTRMQIVNFLQH
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRENGKSSKTLARHIASIRSFHQFLLRERAVEHDPSVHIETPQGERKLPKVLSVSEVEAL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHH
LQTPKTTSAYGIRDKAMLELLYATGLRVSELIALNLEDVHLTMGFVRCVGKGNKERIIPL
HHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCEEEH
GSLATEAIQRYIEKGRKELMGKKAVDALFLNHHGNRLSRQGFWKILKRLAKEANIEKELT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
PHTLRHSFATHLLENGADLRAVQEMLGHADISTTQIYTHVSKTRLKDVYKQFHPRA
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10537218; 10498718 [H]