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The map label for this gene is nagB [H]

Identifier: 152976464

GI number: 152976464

Start: 2837174

End: 2837962

Strand: Reverse

Name: nagB [H]

Synonym: Bcer98_2753

Alternate gene names: 152976464

Gene position: 2837962-2837174 (Counterclockwise)

Preceding gene: 152976465

Following gene: 152976463

Centisome position: 69.44

GC content: 38.53

Gene sequence:

>789_bases
ATGAATATTCTTGTTGTAGAATCTCAAGAAAAATTAGCCGAAGCAGGTTATAAATTAATCGAAAATGTTGTAAAATCAAA
GGGAAATCCAACTTTAGGAATGGCTACAGGAAGCTCTCCACTTGGAATTTATGCAGAAATAAGAAAAAATAAACTTGATA
CAAGCCATGTAACCACTGTAAACTTAGATGAGTACGTAAACTTACCACATGAAGATAAAAACAGCTATCATTATTTTATG
AAAGAACAGCTGTTTGATCATCTTCCATTTAAAGCAACTTATGTACCGAACGGGATGGCAAACGATTTAGAGGAAGAGTG
CAATCGTTATGAAGGCATTCTAGCAGCTAACCCAGTTGACTTACAGATTCTTGGAATCGGTGAAAACGGTCATATCGGAT
TTAATGAGCCAGGAACGCCATTTCATTCTCGAACTCATATTGTAGAATTAACAGAGTCTACACGCCAAGCGAACCGCCGC
TTTTTTGAAAAAGAAGAAGATGTACCAACGCATGCAATTACGATGGGAATTGGAAGCATCATGAAAGCAAAGCAAATTCT
ACTTGTTGCTATGGGACCGAAAAAGGCGGAAGCAGTTAAAGAATTATTGCAAGGAGAGTATAGCGAAGCGTGTCCTGCTA
CAGTTCTGCAACGTCATCCGAATGTAACCGTAATCGCTGATCAAGAAGCTCTATCTTTATGCAGTGAGGCGATTGCTGAT
GAACATCGACAAGTATTCACCATTTCCGATCTATTATCAGATTCAAGAGTGGGTGAAACAGCTAATTGA

Upstream 100 bases:

>100_bases
GCAGTAGGAAAAGATGCAGACTTCGTTGTAATGAATGAAGATTTACATGTATATGATACAGTTCGTTTAGGAATTCATAT
GAAGAAAGGGAAGGAATAAG

Downstream 100 bases:

>100_bases
GGACGGTGAATGGAAGCCGGGAGATAAAATTCCATCTGAAAATGAACTTTGTGATAAGTTTGAAGTAAGTCGTATGACAA
TTAGACAGGCAATTAATAAC

Product: glucosamine-6-phosphate deaminase

Products: NA

Alternate protein names: GlcN6P deaminase; GNPDA; Glucosamine-6-phosphate isomerase [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MNILVVESQEKLAEAGYKLIENVVKSKGNPTLGMATGSSPLGIYAEIRKNKLDTSHVTTVNLDEYVNLPHEDKNSYHYFM
KEQLFDHLPFKATYVPNGMANDLEEECNRYEGILAANPVDLQILGIGENGHIGFNEPGTPFHSRTHIVELTESTRQANRR
FFEKEEDVPTHAITMGIGSIMKAKQILLVAMGPKKAEAVKELLQGEYSEACPATVLQRHPNVTVIADQEALSLCSEAIAD
EHRQVFTISDLLSDSRVGETAN

Sequences:

>Translated_262_residues
MNILVVESQEKLAEAGYKLIENVVKSKGNPTLGMATGSSPLGIYAEIRKNKLDTSHVTTVNLDEYVNLPHEDKNSYHYFM
KEQLFDHLPFKATYVPNGMANDLEEECNRYEGILAANPVDLQILGIGENGHIGFNEPGTPFHSRTHIVELTESTRQANRR
FFEKEEDVPTHAITMGIGSIMKAKQILLVAMGPKKAEAVKELLQGEYSEACPATVLQRHPNVTVIADQEALSLCSEAIAD
EHRQVFTISDLLSDSRVGETAN
>Mature_262_residues
MNILVVESQEKLAEAGYKLIENVVKSKGNPTLGMATGSSPLGIYAEIRKNKLDTSHVTTVNLDEYVNLPHEDKNSYHYFM
KEQLFDHLPFKATYVPNGMANDLEEECNRYEGILAANPVDLQILGIGENGHIGFNEPGTPFHSRTHIVELTESTRQANRR
FFEKEEDVPTHAITMGIGSIMKAKQILLVAMGPKKAEAVKELLQGEYSEACPATVLQRHPNVTVIADQEALSLCSEAIAD
EHRQVFTISDLLSDSRVGETAN

Specific function: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily [H]

Homologues:

Organism=Homo sapiens, GI13027378, Length=243, Percent_Identity=35.3909465020576, Blast_Score=155, Evalue=3e-38,
Organism=Homo sapiens, GI19923881, Length=243, Percent_Identity=32.9218106995885, Blast_Score=143, Evalue=1e-34,
Organism=Escherichia coli, GI1786893, Length=242, Percent_Identity=33.0578512396694, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1789530, Length=228, Percent_Identity=30.2631578947368, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI48994958, Length=251, Percent_Identity=28.2868525896414, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17554876, Length=242, Percent_Identity=35.9504132231405, Blast_Score=152, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24581960, Length=243, Percent_Identity=34.156378600823, Blast_Score=155, Evalue=2e-38,
Organism=Drosophila melanogaster, GI19920764, Length=243, Percent_Identity=34.156378600823, Blast_Score=155, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006148
- InterPro:   IPR004547
- InterPro:   IPR018321 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.5.99.6 [H]

Molecular weight: Translated: 29022; Mature: 29022

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS01161 GLC_GALNAC_ISOMERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILVVESQEKLAEAGYKLIENVVKSKGNPTLGMATGSSPLGIYAEIRKNKLDTSHVTTV
CEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCEEEE
NLDEYVNLPHEDKNSYHYFMKEQLFDHLPFKATYVPNGMANDLEEECNRYEGILAANPVD
EHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCEEECCCCE
LQILGIGENGHIGFNEPGTPFHSRTHIVELTESTRQANRRFFEKEEDVPTHAITMGIGSI
EEEEEECCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
MKAKQILLVAMGPKKAEAVKELLQGEYSEACPATVLQRHPNVTVIADQEALSLCSEAIAD
HHHCEEEEEEECCHHHHHHHHHHCCCCCCCCHHHHHHCCCCEEEEECHHHHHHHHHHHHH
EHRQVFTISDLLSDSRVGETAN
HHHEEEEHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNILVVESQEKLAEAGYKLIENVVKSKGNPTLGMATGSSPLGIYAEIRKNKLDTSHVTTV
CEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCEEEE
NLDEYVNLPHEDKNSYHYFMKEQLFDHLPFKATYVPNGMANDLEEECNRYEGILAANPVD
EHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCEEECCCCE
LQILGIGENGHIGFNEPGTPFHSRTHIVELTESTRQANRRFFEKEEDVPTHAITMGIGSI
EEEEEECCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
MKAKQILLVAMGPKKAEAVKELLQGEYSEACPATVLQRHPNVTVIADQEALSLCSEAIAD
HHHCEEEEEEECCHHHHHHHHHHCCCCCCCCHHHHHHCCCCEEEEECHHHHHHHHHHHHH
EHRQVFTISDLLSDSRVGETAN
HHHEEEEHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA