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The map label for this gene is malL [H]

Identifier: 152976428

GI number: 152976428

Start: 2802740

End: 2804419

Strand: Reverse

Name: malL [H]

Synonym: Bcer98_2716

Alternate gene names: 152976428

Gene position: 2804419-2802740 (Counterclockwise)

Preceding gene: 152976430

Following gene: 152976426

Centisome position: 68.62

GC content: 33.81

Gene sequence:

>1680_bases
ATGACAAAGCAATGGTGGAAAGAAAGTGTTGTCTATCAAATTTATCCACGTAGTTTTATGGATAGCAATGGTGATGGAAT
TGGTGATCTTCGAGGGATTATTTCAAAGTTAGATTATTTACAGAAATTAGGGATAGATGTTGTTTGGTTATCTCCAGTCT
ATGAATCTCCCAATGATGATAATGGTTATGATATTAGTGACTATCGTAAAATTATGACTGAGTTTGGGACAATGGAAGAT
TGGGAAGAGTTATTACATGAAATGCATAAGCGTAATATAAAATTAATGATGGATTTAGTGGTTAATCATACTTCTGATGA
ACATAATTGGTTTATAGAGTCACGTAAGTCCAAAGATAATCCATATCGGGATTACTATATTTGGCGATCAGGAAAAGAGG
GGAAAGAGCCAAATAATTGGGAATCAGCTTTTAGCGGATCTGCTTGGCAATATGATGAAACAACGGATGAATATTATTTG
CATTTATTTTCTAAAAAGCAACCGGATTTAAATTGGGATAATGAACAAGTACGAAAAGATGTTTATGATATGATGAAATT
TTGGTTTGAAAAAGGGATAGATGGTTTTCGTATGGATGTCATTAACTTTATCTCCAAAGAAGAAGGATTACCAACTGTGG
AAACAGAGGAAAAGGGGTATGTATCTGGGCATCAATATTTTATGAATGGGCCGAATATTCATACGTATTTGCATGAAATG
AATCGAGAAGTATTATCAAAATATGATATTATGACCGTTGGTGAAATGCCTGGTGTCACAACAGAAGAAGCTAAACTTTA
TACAGCGGAAGAACGTCAAGAATTACAGATGGTATTTCAATTTGAACACATGGACTTAGATTCTGGAGAAGGTGGAAAAT
GGGATATAAAGCCATATTCTCTTCTTACGCTAAAACAAAATTTAACAAAATGGCAAAAAGCTCTTGAATATACAGGATGG
AACAGCTTGTATTGGAATAATCATGACCAACCTCGCGTTGTCTCTCGCTTTGGCAATGATACAACCTATCGCATAGAAGC
AGCGAAAATGTTGGCGACGGTACTTCATATGATGAAAGGTACTCCTTACATTTATCAAGGAGAGGAAATTGGAATGACAA
ATGTTCGTTTTGATTCCATTAATGAATATCGTGATATTGAAACATTAAATATGTATCGTGAAAAAGTAATTGAGCGCGGT
GAAAATGAAGAACAAGTGATGCAATCTATTTATGTAAAAGGGCGAGATAATGCACGTACTCCAATGCAGTGGAATCAGGA
TAAGCACGCTGGATTTACGACTGGGGAACCATGGATTAGAGTCAATCCTAATTATAAAGAGATTAATGTAGAACAAGCAT
TACAAGATTCAGAATCAATTTTTTATTACTATAAAAAATTGATTGAGCTTCGTAAAAAACATGAAATCATTGTGTATGGT
ACATATGATTTAATATTAGAGAACCATCCATCAATTTTTGCTTATGTAAGAACATGGAAAGATGAACAATTACTTGTCAT
TGCGAATTTTACTGAGAATGAGTGTTTGTTTGAACTCCCGAAAGAGATAACTTATTATCTTTCAGAATTAGTCATTCACA
ATTATGATGTGCAAGATGGAACGCTTGAAAGTTTTGTTTTACAGCCGTATGAAGCAAGAGTGTATAAATTAAAATCATAA

Upstream 100 bases:

>100_bases
AAATAAAACGTTTTCATTTTTTCTGGAATTTGATATCATTCATTAATGAAAACGCTTGCGTTAAAAAATCATTTTATTAA
AGAGAAATGGAGGTAGCAAG

Downstream 100 bases:

>100_bases
AAAGTCTTGAGGTAGCAAAAAAACTTATTTTTTAATTTTAAAATTGGTCAAATGAATAAAGAGTTAGATGAAATGTAGAA
TCATTGGATAAATAAAGAGC

Product: alpha amylase catalytic region

Products: NA

Alternate protein names: Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase [H]

Number of amino acids: Translated: 559; Mature: 558

Protein sequence:

>559_residues
MTKQWWKESVVYQIYPRSFMDSNGDGIGDLRGIISKLDYLQKLGIDVVWLSPVYESPNDDNGYDISDYRKIMTEFGTMED
WEELLHEMHKRNIKLMMDLVVNHTSDEHNWFIESRKSKDNPYRDYYIWRSGKEGKEPNNWESAFSGSAWQYDETTDEYYL
HLFSKKQPDLNWDNEQVRKDVYDMMKFWFEKGIDGFRMDVINFISKEEGLPTVETEEKGYVSGHQYFMNGPNIHTYLHEM
NREVLSKYDIMTVGEMPGVTTEEAKLYTAEERQELQMVFQFEHMDLDSGEGGKWDIKPYSLLTLKQNLTKWQKALEYTGW
NSLYWNNHDQPRVVSRFGNDTTYRIEAAKMLATVLHMMKGTPYIYQGEEIGMTNVRFDSINEYRDIETLNMYREKVIERG
ENEEQVMQSIYVKGRDNARTPMQWNQDKHAGFTTGEPWIRVNPNYKEINVEQALQDSESIFYYYKKLIELRKKHEIIVYG
TYDLILENHPSIFAYVRTWKDEQLLVIANFTENECLFELPKEITYYLSELVIHNYDVQDGTLESFVLQPYEARVYKLKS

Sequences:

>Translated_559_residues
MTKQWWKESVVYQIYPRSFMDSNGDGIGDLRGIISKLDYLQKLGIDVVWLSPVYESPNDDNGYDISDYRKIMTEFGTMED
WEELLHEMHKRNIKLMMDLVVNHTSDEHNWFIESRKSKDNPYRDYYIWRSGKEGKEPNNWESAFSGSAWQYDETTDEYYL
HLFSKKQPDLNWDNEQVRKDVYDMMKFWFEKGIDGFRMDVINFISKEEGLPTVETEEKGYVSGHQYFMNGPNIHTYLHEM
NREVLSKYDIMTVGEMPGVTTEEAKLYTAEERQELQMVFQFEHMDLDSGEGGKWDIKPYSLLTLKQNLTKWQKALEYTGW
NSLYWNNHDQPRVVSRFGNDTTYRIEAAKMLATVLHMMKGTPYIYQGEEIGMTNVRFDSINEYRDIETLNMYREKVIERG
ENEEQVMQSIYVKGRDNARTPMQWNQDKHAGFTTGEPWIRVNPNYKEINVEQALQDSESIFYYYKKLIELRKKHEIIVYG
TYDLILENHPSIFAYVRTWKDEQLLVIANFTENECLFELPKEITYYLSELVIHNYDVQDGTLESFVLQPYEARVYKLKS
>Mature_558_residues
TKQWWKESVVYQIYPRSFMDSNGDGIGDLRGIISKLDYLQKLGIDVVWLSPVYESPNDDNGYDISDYRKIMTEFGTMEDW
EELLHEMHKRNIKLMMDLVVNHTSDEHNWFIESRKSKDNPYRDYYIWRSGKEGKEPNNWESAFSGSAWQYDETTDEYYLH
LFSKKQPDLNWDNEQVRKDVYDMMKFWFEKGIDGFRMDVINFISKEEGLPTVETEEKGYVSGHQYFMNGPNIHTYLHEMN
REVLSKYDIMTVGEMPGVTTEEAKLYTAEERQELQMVFQFEHMDLDSGEGGKWDIKPYSLLTLKQNLTKWQKALEYTGWN
SLYWNNHDQPRVVSRFGNDTTYRIEAAKMLATVLHMMKGTPYIYQGEEIGMTNVRFDSINEYRDIETLNMYREKVIERGE
NEEQVMQSIYVKGRDNARTPMQWNQDKHAGFTTGEPWIRVNPNYKEINVEQALQDSESIFYYYKKLIELRKKHEIIVYGT
YDLILENHPSIFAYVRTWKDEQLLVIANFTENECLFELPKEITYYLSELVIHNYDVQDGTLESFVLQPYEARVYKLKS

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=537, Percent_Identity=30.3538175046555, Blast_Score=247, Evalue=2e-65,
Organism=Escherichia coli, GI1790687, Length=556, Percent_Identity=46.2230215827338, Blast_Score=546, Evalue=1e-157,
Organism=Escherichia coli, GI1786604, Length=246, Percent_Identity=26.0162601626016, Blast_Score=82, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI32565753, Length=564, Percent_Identity=22.6950354609929, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI25147709, Length=206, Percent_Identity=29.6116504854369, Blast_Score=100, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6322245, Length=578, Percent_Identity=40.8304498269896, Blast_Score=447, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6321726, Length=576, Percent_Identity=40.2777777777778, Blast_Score=444, Evalue=1e-125,
Organism=Saccharomyces cerevisiae, GI6324416, Length=576, Percent_Identity=40.4513888888889, Blast_Score=430, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6322241, Length=576, Percent_Identity=40.4513888888889, Blast_Score=429, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6322021, Length=576, Percent_Identity=40.4513888888889, Blast_Score=429, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6319776, Length=579, Percent_Identity=40.2417962003454, Blast_Score=417, Evalue=1e-117,
Organism=Saccharomyces cerevisiae, GI6321731, Length=579, Percent_Identity=40.0690846286701, Blast_Score=416, Evalue=1e-117,
Organism=Drosophila melanogaster, GI24583749, Length=540, Percent_Identity=36.1111111111111, Blast_Score=301, Evalue=1e-81,
Organism=Drosophila melanogaster, GI24583747, Length=540, Percent_Identity=36.1111111111111, Blast_Score=301, Evalue=1e-81,
Organism=Drosophila melanogaster, GI24583745, Length=537, Percent_Identity=36.1266294227188, Blast_Score=300, Evalue=2e-81,
Organism=Drosophila melanogaster, GI221330053, Length=590, Percent_Identity=33.2203389830508, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24586593, Length=503, Percent_Identity=34.9900596421471, Blast_Score=277, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24586587, Length=587, Percent_Identity=32.0272572402044, Blast_Score=269, Evalue=5e-72,
Organism=Drosophila melanogaster, GI24586599, Length=593, Percent_Identity=32.0404721753794, Blast_Score=268, Evalue=9e-72,
Organism=Drosophila melanogaster, GI24586597, Length=561, Percent_Identity=32.2638146167558, Blast_Score=267, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24586591, Length=587, Percent_Identity=32.7086882453152, Blast_Score=266, Evalue=3e-71,
Organism=Drosophila melanogaster, GI45549022, Length=506, Percent_Identity=31.6205533596838, Blast_Score=256, Evalue=3e-68,
Organism=Drosophila melanogaster, GI24586589, Length=587, Percent_Identity=32.7086882453152, Blast_Score=256, Evalue=3e-68,
Organism=Drosophila melanogaster, GI281360393, Length=455, Percent_Identity=32.7472527472527, Blast_Score=201, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.10 [H]

Molecular weight: Translated: 66621; Mature: 66489

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKQWWKESVVYQIYPRSFMDSNGDGIGDLRGIISKLDYLQKLGIDVVWLSPVYESPNDD
CCHHHHHHCCEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCC
NGYDISDYRKIMTEFGTMEDWEELLHEMHKRNIKLMMDLVVNHTSDEHNWFIESRKSKDN
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEECCCCCCC
PYRDYYIWRSGKEGKEPNNWESAFSGSAWQYDETTDEYYLHLFSKKQPDLNWDNEQVRKD
CCCEEEEEECCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHEECCCCCCCCCCCHHHHHHH
VYDMMKFWFEKGIDGFRMDVINFISKEEGLPTVETEEKGYVSGHQYFMNGPNIHTYLHEM
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHH
NREVLSKYDIMTVGEMPGVTTEEAKLYTAEERQELQMVFQFEHMDLDSGEGGKWDIKPYS
HHHHHHHCCEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCEECCCCEE
LLTLKQNLTKWQKALEYTGWNSLYWNNHDQPRVVSRFGNDTTYRIEAAKMLATVLHMMKG
EEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCEEEEHHHHHHHHHHHHHCC
TPYIYQGEEIGMTNVRFDSINEYRDIETLNMYREKVIERGENEEQVMQSIYVKGRDNART
CCEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCC
PMQWNQDKHAGFTTGEPWIRVNPNYKEINVEQALQDSESIFYYYKKLIELRKKHEIIVYG
CCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCEEEEE
TYDLILENHPSIFAYVRTWKDEQLLVIANFTENECLFELPKEITYYLSELVIHNYDVQDG
EEEEEECCCCCEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
TLESFVLQPYEARVYKLKS
CHHHHHHCCCCCEEEEECC
>Mature Secondary Structure 
TKQWWKESVVYQIYPRSFMDSNGDGIGDLRGIISKLDYLQKLGIDVVWLSPVYESPNDD
CHHHHHHCCEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCC
NGYDISDYRKIMTEFGTMEDWEELLHEMHKRNIKLMMDLVVNHTSDEHNWFIESRKSKDN
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEECCCCCCC
PYRDYYIWRSGKEGKEPNNWESAFSGSAWQYDETTDEYYLHLFSKKQPDLNWDNEQVRKD
CCCEEEEEECCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHEECCCCCCCCCCCHHHHHHH
VYDMMKFWFEKGIDGFRMDVINFISKEEGLPTVETEEKGYVSGHQYFMNGPNIHTYLHEM
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHH
NREVLSKYDIMTVGEMPGVTTEEAKLYTAEERQELQMVFQFEHMDLDSGEGGKWDIKPYS
HHHHHHHCCEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCEECCCCEE
LLTLKQNLTKWQKALEYTGWNSLYWNNHDQPRVVSRFGNDTTYRIEAAKMLATVLHMMKG
EEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCEEEEHHHHHHHHHHHHHCC
TPYIYQGEEIGMTNVRFDSINEYRDIETLNMYREKVIERGENEEQVMQSIYVKGRDNART
CCEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCC
PMQWNQDKHAGFTTGEPWIRVNPNYKEINVEQALQDSESIFYYYKKLIELRKKHEIIVYG
CCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCEEEEE
TYDLILENHPSIFAYVRTWKDEQLLVIANFTENECLFELPKEITYYLSELVIHNYDVQDG
EEEEEECCCCCEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
TLESFVLQPYEARVYKLKS
CHHHHHHCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2120057; 8370659; 9193006 [H]