Click here to switch to the map view.

The map label for this gene is panE [H]

Identifier: 152976282

GI number: 152976282

Start: 2673518

End: 2674408

Strand: Reverse

Name: panE [H]

Synonym: Bcer98_2570

Alternate gene names: 152976282

Gene position: 2674408-2673518 (Counterclockwise)

Preceding gene: 152976284

Following gene: 152976281

Centisome position: 65.44

GC content: 33.22

Gene sequence:

>891_bases
ATGTCCATAAATATGAAAATTGGAATTGTTGGCCCTGGAGCTATTGGTTTGTTATATGCGTTTTATTTTAAAAAAAGTAA
TCAAGATGTTACATTGTTTACAAGAACTGTTGAGCAAGCGAAACAATTAGAAAAAACAGGGGTAACTTGTATTCAGGATG
AAATATCAGAAACGGTGTTTCCGAAAGTATTACCAGTAGAAAGCGTTGAAAAGGAGAACTGGGACTATATATTTATTGCT
GTCAAGCAATATCATGTAAATCATATACTCCCTTTTCTAAGTAAGCAGCGAGTCGTATTTTTACAAAATGGGATGTCTCA
TCTTCAGCTTATAAAAGAATTACAGTGTGAAAATATAGCTGTAGGTATTGTCGAACATGGAGCCAAAAAAGAAAATTTTC
ATACGGTATGTCATACGGGAGTAGGAATCACAAAATTTGGTGTTGTTAAAGGTGATGTGCTTCAATTTGAACCGATATTT
GAGTGTTTTGCTTCGCAACGTTTTTCTATGCAATTTGAAGATGACTGGAAACAGATGATGTACAATAAATTAATCGTAAA
TGTTTGTATTAATCCATTAACAGCTTTATTTGGAGTTTGTAATGGAGAGTTGATATCCAACCCTTTCTTTTATCAATCGA
TGAAGCAAGTATTTCAAGAAGTTACATTTCTTATTGAAAAAGAGAAAGAAGAAGAGTTATGGAATATGGTGTGTCAAGTG
TGTCAAAAAACATCTTGTAATACTTCTTCTATGTTAGCTGATATACGAGAGAAGCGAAAAACAGAAATTGAAGCGATCGT
TGGGTATGTTTTAGATGAAGCGAAAGCACGGCAGAAACAAGTACATATACTTCCATTCTTATACAATGCGATAAGAGGTT
TAGAAACATAA

Upstream 100 bases:

>100_bases
ATTTTAAAATAGAGATCAAATATATGAATGGAGAGGAGTTAAGGAGCTTTAAAGGGATAGCAACGTAATCTGTACAACTT
GTTATTGATACAAAGCTCTT

Downstream 100 bases:

>100_bases
GTTATATTCTTTGCTTTTGGGCGAAACATTGACTACAATTTGGAATGGTGAAAGAACAGGATATGAAAGGAAGAATTATA
TGGAGATAAAAGAAATCTCT

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSINMKIGIVGPGAIGLLYAFYFKKSNQDVTLFTRTVEQAKQLEKTGVTCIQDEISETVFPKVLPVESVEKENWDYIFIA
VKQYHVNHILPFLSKQRVVFLQNGMSHLQLIKELQCENIAVGIVEHGAKKENFHTVCHTGVGITKFGVVKGDVLQFEPIF
ECFASQRFSMQFEDDWKQMMYNKLIVNVCINPLTALFGVCNGELISNPFFYQSMKQVFQEVTFLIEKEKEEELWNMVCQV
CQKTSCNTSSMLADIREKRKTEIEAIVGYVLDEAKARQKQVHILPFLYNAIRGLET

Sequences:

>Translated_296_residues
MSINMKIGIVGPGAIGLLYAFYFKKSNQDVTLFTRTVEQAKQLEKTGVTCIQDEISETVFPKVLPVESVEKENWDYIFIA
VKQYHVNHILPFLSKQRVVFLQNGMSHLQLIKELQCENIAVGIVEHGAKKENFHTVCHTGVGITKFGVVKGDVLQFEPIF
ECFASQRFSMQFEDDWKQMMYNKLIVNVCINPLTALFGVCNGELISNPFFYQSMKQVFQEVTFLIEKEKEEELWNMVCQV
CQKTSCNTSSMLADIREKRKTEIEAIVGYVLDEAKARQKQVHILPFLYNAIRGLET
>Mature_295_residues
SINMKIGIVGPGAIGLLYAFYFKKSNQDVTLFTRTVEQAKQLEKTGVTCIQDEISETVFPKVLPVESVEKENWDYIFIAV
KQYHVNHILPFLSKQRVVFLQNGMSHLQLIKELQCENIAVGIVEHGAKKENFHTVCHTGVGITKFGVVKGDVLQFEPIFE
CFASQRFSMQFEDDWKQMMYNKLIVNVCINPLTALFGVCNGELISNPFFYQSMKQVFQEVTFLIEKEKEEELWNMVCQVC
QKTSCNTSSMLADIREKRKTEIEAIVGYVLDEAKARQKQVHILPFLYNAIRGLET

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786627, Length=283, Percent_Identity=26.8551236749117, Blast_Score=101, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 33959; Mature: 33828

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS00065 D_2_HYDROXYACID_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSINMKIGIVGPGAIGLLYAFYFKKSNQDVTLFTRTVEQAKQLEKTGVTCIQDEISETVF
CCEEEEEEEECCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHC
PKVLPVESVEKENWDYIFIAVKQYHVNHILPFLSKQRVVFLQNGMSHLQLIKELQCENIA
CCCCCCHHHCCCCCCEEEEEEEHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCCEE
VGIVEHGAKKENFHTVCHTGVGITKFGVVKGDVLQFEPIFECFASQRFSMQFEDDWKQMM
EEHHHCCCCCCCCHHHHHCCCCCHHCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHH
YNKLIVNVCINPLTALFGVCNGELISNPFFYQSMKQVFQEVTFLIEKEKEEELWNMVCQV
HHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CQKTSCNTSSMLADIREKRKTEIEAIVGYVLDEAKARQKQVHILPFLYNAIRGLET
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SINMKIGIVGPGAIGLLYAFYFKKSNQDVTLFTRTVEQAKQLEKTGVTCIQDEISETVF
CEEEEEEEECCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHC
PKVLPVESVEKENWDYIFIAVKQYHVNHILPFLSKQRVVFLQNGMSHLQLIKELQCENIA
CCCCCCHHHCCCCCCEEEEEEEHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCCEE
VGIVEHGAKKENFHTVCHTGVGITKFGVVKGDVLQFEPIFECFASQRFSMQFEDDWKQMM
EEHHHCCCCCCCCHHHHHCCCCCHHCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHH
YNKLIVNVCINPLTALFGVCNGELISNPFFYQSMKQVFQEVTFLIEKEKEEELWNMVCQV
HHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CQKTSCNTSSMLADIREKRKTEIEAIVGYVLDEAKARQKQVHILPFLYNAIRGLET
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]