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The map label for this gene is mraW [H]

Identifier: 152976280

GI number: 152976280

Start: 2670526

End: 2671458

Strand: Reverse

Name: mraW [H]

Synonym: Bcer98_2568

Alternate gene names: 152976280

Gene position: 2671458-2670526 (Counterclockwise)

Preceding gene: 152976281

Following gene: 152976279

Centisome position: 65.36

GC content: 37.19

Gene sequence:

>933_bases
ATGTTTAAACACGTAACAGTGCTTTTAGAGGAAACAGTAGATGGCTTGGATATAAAGCCAAATGGTACATATGTAGATTG
TACACTAGGTGGTGGAGGACATAGTTCCTATTTGTTATCTCAGCTAACGGAAGGAGGAAAGTTAATTGCATTTGATCAAG
ATGAAATTGCAATTCAAAATGCAAAAGACAAATTTTCTTCTTATGGTGAGCAATTTATAGCAGTAAAAAGTAATTTTCGT
TATTTATCAGAGAAACTACATGAGTTAGGGATTACAGAAGTAGATGGGATTTTATTTGACTTAGGTGTTTCTTCTCCACA
ATTAGATACACCAGAACGCGGTTTTAGCTATCATCATGATGCACCGTTAGATATGCGAATGGACCAAGAAGCTCCATTAA
CAGCATATGATGTTGTGAATAATTGGTCATATGAGCAACTTGTAAGGATTTTCTTTCAATATGGTGAAGAGAAATTTTCA
AAACAAATTGCAAGGAAAATTGAAGCGTATCGTGAAAAGAAGAAAATTGAAACGACTGGGGAATTAGTGGAGTTAATCAA
AGAAGGAATTCCTGCTCCTGCTCGTAGGACTGGCGGACATCCTGCAAAACGAGTGTTTCAAGCGATTCGCATTGCTGTAA
ATGATGAGTTGAAAGTATTTGAGGAAGCGTTGGAAGCGGCAATTGAAATAGTGAAACCTGGTGGAAGAATTAGCGTTATT
ACGTTCCATTCACTAGAAGATCGTATTTGCAAAACAACATTTAAACGAAATAGTACAACACCAGAGCTCCCTCCAGGATT
GCCGATTATTCCAGAGGAGTTTAAGCCGAAACTAAAGCTTATTACAAGAAAACCGATTTTACCATCTGACGTAGAGTTAG
AAGAAAATAATCGAGCGCGTTCGGCAAAGTTACGGATTGCTGAAAAACGATAA

Upstream 100 bases:

>100_bases
AAATGAGCTGCTTGCTTGTAGTGTTTTATTTCTTCACTAAATTTATAGGGGAAGAGAAAAAAGTTCAACATAATTATTTG
GAAAAAGAGTAGGTGCAACG

Downstream 100 bases:

>100_bases
AAAGGAGAGAGAGGTATGAGTAATTTAGCTGTAAAGTACAAACAACAAATGCAAGAACAAGTACAATCGCAAGCGCCACA
GCAGATGGTACAGCCAAAGA

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MFKHVTVLLEETVDGLDIKPNGTYVDCTLGGGGHSSYLLSQLTEGGKLIAFDQDEIAIQNAKDKFSSYGEQFIAVKSNFR
YLSEKLHELGITEVDGILFDLGVSSPQLDTPERGFSYHHDAPLDMRMDQEAPLTAYDVVNNWSYEQLVRIFFQYGEEKFS
KQIARKIEAYREKKKIETTGELVELIKEGIPAPARRTGGHPAKRVFQAIRIAVNDELKVFEEALEAAIEIVKPGGRISVI
TFHSLEDRICKTTFKRNSTTPELPPGLPIIPEEFKPKLKLITRKPILPSDVELEENNRARSAKLRIAEKR

Sequences:

>Translated_310_residues
MFKHVTVLLEETVDGLDIKPNGTYVDCTLGGGGHSSYLLSQLTEGGKLIAFDQDEIAIQNAKDKFSSYGEQFIAVKSNFR
YLSEKLHELGITEVDGILFDLGVSSPQLDTPERGFSYHHDAPLDMRMDQEAPLTAYDVVNNWSYEQLVRIFFQYGEEKFS
KQIARKIEAYREKKKIETTGELVELIKEGIPAPARRTGGHPAKRVFQAIRIAVNDELKVFEEALEAAIEIVKPGGRISVI
TFHSLEDRICKTTFKRNSTTPELPPGLPIIPEEFKPKLKLITRKPILPSDVELEENNRARSAKLRIAEKR
>Mature_310_residues
MFKHVTVLLEETVDGLDIKPNGTYVDCTLGGGGHSSYLLSQLTEGGKLIAFDQDEIAIQNAKDKFSSYGEQFIAVKSNFR
YLSEKLHELGITEVDGILFDLGVSSPQLDTPERGFSYHHDAPLDMRMDQEAPLTAYDVVNNWSYEQLVRIFFQYGEEKFS
KQIARKIEAYREKKKIETTGELVELIKEGIPAPARRTGGHPAKRVFQAIRIAVNDELKVFEEALEAAIEIVKPGGRISVI
TFHSLEDRICKTTFKRNSTTPELPPGLPIIPEEFKPKLKLITRKPILPSDVELEENNRARSAKLRIAEKR

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA [H]

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family [H]

Homologues:

Organism=Homo sapiens, GI165377209, Length=339, Percent_Identity=35.3982300884956, Blast_Score=168, Evalue=6e-42,
Organism=Homo sapiens, GI165377202, Length=191, Percent_Identity=38.2198952879581, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI1786270, Length=312, Percent_Identity=44.8717948717949, Blast_Score=252, Evalue=2e-68,
Organism=Drosophila melanogaster, GI62472493, Length=329, Percent_Identity=40.1215805471125, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI28571637, Length=329, Percent_Identity=40.1215805471125, Blast_Score=182, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002903 [H]

Pfam domain/function: PF01795 Methyltransf_5 [H]

EC number: NA

Molecular weight: Translated: 35003; Mature: 35003

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKHVTVLLEETVDGLDIKPNGTYVDCTLGGGGHSSYLLSQLTEGGKLIAFDQDEIAIQN
CCCHHEEHHHHCCCCCEECCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEECCCHHHHHH
AKDKFSSYGEQFIAVKSNFRYLSEKLHELGITEVDGILFDLGVSSPQLDTPERGFSYHHD
HHHHHHHHCHHEEEHHHHHHHHHHHHHHCCCCHHCCEEEECCCCCCCCCCCCCCCCCCCC
APLDMRMDQEAPLTAYDVVNNWSYEQLVRIFFQYGEEKFSKQIARKIEAYREKKKIETTG
CCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELVELIKEGIPAPARRTGGHPAKRVFQAIRIAVNDELKVFEEALEAAIEIVKPGGRISVI
HHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEE
TFHSLEDRICKTTFKRNSTTPELPPGLPIIPEEFKPKLKLITRKPILPSDVELEENNRAR
EECCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCHHEEEECCCCCCCCCCCCCCCCCC
SAKLRIAEKR
HHEEEEECCC
>Mature Secondary Structure
MFKHVTVLLEETVDGLDIKPNGTYVDCTLGGGGHSSYLLSQLTEGGKLIAFDQDEIAIQN
CCCHHEEHHHHCCCCCEECCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEECCCHHHHHH
AKDKFSSYGEQFIAVKSNFRYLSEKLHELGITEVDGILFDLGVSSPQLDTPERGFSYHHD
HHHHHHHHCHHEEEHHHHHHHHHHHHHHCCCCHHCCEEEECCCCCCCCCCCCCCCCCCCC
APLDMRMDQEAPLTAYDVVNNWSYEQLVRIFFQYGEEKFSKQIARKIEAYREKKKIETTG
CCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELVELIKEGIPAPARRTGGHPAKRVFQAIRIAVNDELKVFEEALEAAIEIVKPGGRISVI
HHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEE
TFHSLEDRICKTTFKRNSTTPELPPGLPIIPEEFKPKLKLITRKPILPSDVELEENNRAR
EECCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCHHEEEECCCCCCCCCCCCCCCCCC
SAKLRIAEKR
HHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA