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The map label for this gene is ffh [H]

Identifier: 152976211

GI number: 152976211

Start: 2593508

End: 2594857

Strand: Reverse

Name: ffh [H]

Synonym: Bcer98_2497

Alternate gene names: 152976211

Gene position: 2594857-2593508 (Counterclockwise)

Preceding gene: 152976212

Following gene: 152976210

Centisome position: 63.49

GC content: 40.74

Gene sequence:

>1350_bases
ATGGCATTTGAAGGATTAGCCGACCGACTTCAACAGACGATGCAAAAAATCCGCGGCAAAGGAAAAGTTTCCGAAGCCGA
TGTGAAAGAAATGATGAGAGAAGTTCGTCTAGCTCTTTTAGAAGCAGATGTTAACTTTAAGGTTGTAAAAGATTTTGTAA
AGCGTGTGTCTGAGCGTGCTGTCGGACAAGATGTAATGAAAAGTTTAACACCTGGCCAACAAGTCATTAAGGTAGTACAG
GAAGAACTGACAGGGCTTATGGGTGGAGAGCAAAGTAAAATTGCTGTCGCAAATAAGCCACCTACTGTCATTATGATGGT
CGGTTTACAAGGTGCAGGGAAAACAACAACAACAGGGAAACTTGCGAATTTGCTTCGAAAAAAGCATAATCGTAAACCAA
TGCTTGTTGCGGCAGATATTTATCGTCCAGCAGCGATTAAACAGCTTGAAACATTAGGAAAACAATTGGACATGCCTGTA
TTCTCGCTAGGGGATCAAGTGAGTCCAGTAGAAATCGCAAAACAAGCGATTGCTAAGGCGAAAGAAGAACATCATGATTA
TGTTTTAATTGATACGGCAGGTCGTCTGCATATTGATGAAGAACTCATGGATGAATTAGCAAAAGTTAAAGAAGTTGCGA
ATCCTGATGAAATTTTCCTTGTTGTAGATGCAATGACAGGACAAGATGCGGTAAATGTTGCGAAAAGCTTCCATGAACAG
TTAGGTTTAACTGGTGTTGTGTTGACGAAACTAGATGGTGATACGCGCGGTGGTGCAGCGCTATCTATTAAAGCGGTAAC
GAATACACCAATTAAATTTGCAGGTATGGGCGAAAAGCTAGATGCCATTGAACCGTTTCATCCAGAACGTATGGCCTCTC
GTATTTTAGGGATGGGTGACGTTCTGACATTAATTGAAAAGGCGCAAGCTACAGTTGATGAAGAAAAGGCAAAAGAGCTT
GAGCAAAAAATGCGTACGCTCTCGTTTACACTGGATGATTTCCTGGAACAACTTGGACAAGTGCGTCAACTTGGACCGCT
TGATGAGTTATTAGGAATGCTTCCTGGTGCGAATAAAATAAAAGGGCTCAAAAATGCAAAAGTTGATGACAAGCAAATTG
GGCATATTGAAGCAATTATTCGTTCTATGACAAAACTAGAGCGAGAACAACCGGAAATAATCAATGCTAGTCGAAAAAAA
CGTATCGCCAAAGGCAGTGGTACAACTGTACAAGAAATTAATCGTCTCCTCAAACAGTTTGAAGACATGAAAAAAATGAT
GAAGACGCTGACAGGCATGCAAAAAGGGAAGAAAAAAGGACTAGGTGGATTGAAGTTTCCATTTATGTAA

Upstream 100 bases:

>100_bases
TGCAGAGCTAAAACAGCTTATCAATGAAGAAGAGCATGTGAATGACAAGATGAAACAAGTTGTTGAAGATATCGAAAAAC
TAGATTAGGAGGGCGGCAAT

Downstream 100 bases:

>100_bases
GAGAAAAAAGATAGCTCTGTTAAGAAAAAATACTTTACAAAGCAATAGTCTTTTTGCTAATATAATTATCTGTGTGAAAT
AAATTCGGAGGTGCTTTATA

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MAFEGLADRLQQTMQKIRGKGKVSEADVKEMMREVRLALLEADVNFKVVKDFVKRVSERAVGQDVMKSLTPGQQVIKVVQ
EELTGLMGGEQSKIAVANKPPTVIMMVGLQGAGKTTTTGKLANLLRKKHNRKPMLVAADIYRPAAIKQLETLGKQLDMPV
FSLGDQVSPVEIAKQAIAKAKEEHHDYVLIDTAGRLHIDEELMDELAKVKEVANPDEIFLVVDAMTGQDAVNVAKSFHEQ
LGLTGVVLTKLDGDTRGGAALSIKAVTNTPIKFAGMGEKLDAIEPFHPERMASRILGMGDVLTLIEKAQATVDEEKAKEL
EQKMRTLSFTLDDFLEQLGQVRQLGPLDELLGMLPGANKIKGLKNAKVDDKQIGHIEAIIRSMTKLEREQPEIINASRKK
RIAKGSGTTVQEINRLLKQFEDMKKMMKTLTGMQKGKKKGLGGLKFPFM

Sequences:

>Translated_449_residues
MAFEGLADRLQQTMQKIRGKGKVSEADVKEMMREVRLALLEADVNFKVVKDFVKRVSERAVGQDVMKSLTPGQQVIKVVQ
EELTGLMGGEQSKIAVANKPPTVIMMVGLQGAGKTTTTGKLANLLRKKHNRKPMLVAADIYRPAAIKQLETLGKQLDMPV
FSLGDQVSPVEIAKQAIAKAKEEHHDYVLIDTAGRLHIDEELMDELAKVKEVANPDEIFLVVDAMTGQDAVNVAKSFHEQ
LGLTGVVLTKLDGDTRGGAALSIKAVTNTPIKFAGMGEKLDAIEPFHPERMASRILGMGDVLTLIEKAQATVDEEKAKEL
EQKMRTLSFTLDDFLEQLGQVRQLGPLDELLGMLPGANKIKGLKNAKVDDKQIGHIEAIIRSMTKLEREQPEIINASRKK
RIAKGSGTTVQEINRLLKQFEDMKKMMKTLTGMQKGKKKGLGGLKFPFM
>Mature_448_residues
AFEGLADRLQQTMQKIRGKGKVSEADVKEMMREVRLALLEADVNFKVVKDFVKRVSERAVGQDVMKSLTPGQQVIKVVQE
ELTGLMGGEQSKIAVANKPPTVIMMVGLQGAGKTTTTGKLANLLRKKHNRKPMLVAADIYRPAAIKQLETLGKQLDMPVF
SLGDQVSPVEIAKQAIAKAKEEHHDYVLIDTAGRLHIDEELMDELAKVKEVANPDEIFLVVDAMTGQDAVNVAKSFHEQL
GLTGVVLTKLDGDTRGGAALSIKAVTNTPIKFAGMGEKLDAIEPFHPERMASRILGMGDVLTLIEKAQATVDEEKAKELE
QKMRTLSFTLDDFLEQLGQVRQLGPLDELLGMLPGANKIKGLKNAKVDDKQIGHIEAIIRSMTKLEREQPEIINASRKKR
IAKGSGTTVQEINRLLKQFEDMKKMMKTLTGMQKGKKKGLGGLKFPFM

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=452, Percent_Identity=32.3008849557522, Blast_Score=225, Evalue=5e-59,
Organism=Homo sapiens, GI226371618, Length=351, Percent_Identity=35.042735042735, Blast_Score=205, Evalue=8e-53,
Organism=Homo sapiens, GI89061728, Length=144, Percent_Identity=39.5833333333333, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI23308697, Length=293, Percent_Identity=27.6450511945392, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI295424842, Length=293, Percent_Identity=27.6450511945392, Blast_Score=99, Evalue=9e-21,
Organism=Escherichia coli, GI1788963, Length=424, Percent_Identity=54.4811320754717, Blast_Score=467, Evalue=1e-133,
Organism=Escherichia coli, GI1789874, Length=251, Percent_Identity=36.2549800796813, Blast_Score=155, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17539958, Length=448, Percent_Identity=29.9107142857143, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI193206261, Length=285, Percent_Identity=30.5263157894737, Blast_Score=102, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6325345, Length=420, Percent_Identity=33.8095238095238, Blast_Score=233, Evalue=4e-62,
Organism=Saccharomyces cerevisiae, GI6320498, Length=306, Percent_Identity=29.0849673202614, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI17647949, Length=454, Percent_Identity=30.8370044052863, Blast_Score=208, Evalue=6e-54,
Organism=Drosophila melanogaster, GI24641198, Length=301, Percent_Identity=26.9102990033223, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 49454; Mature: 49323

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFEGLADRLQQTMQKIRGKGKVSEADVKEMMREVRLALLEADVNFKVVKDFVKRVSERA
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
VGQDVMKSLTPGQQVIKVVQEELTGLMGGEQSKIAVANKPPTVIMMVGLQGAGKTTTTGK
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEEECCCCCCCCCHHH
LANLLRKKHNRKPMLVAADIYRPAAIKQLETLGKQLDMPVFSLGDQVSPVEIAKQAIAKA
HHHHHHHHHCCCCEEEEHHHHCHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHH
KEEHHDYVLIDTAGRLHIDEELMDELAKVKEVANPDEIFLVVDAMTGQDAVNVAKSFHEQ
HHHCCCEEEEECCCCEEECHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHH
LGLTGVVLTKLDGDTRGGAALSIKAVTNTPIKFAGMGEKLDAIEPFHPERMASRILGMGD
HCCCEEEEEEECCCCCCCCEEEEEEECCCCEEECCCCCCCCCCCCCCHHHHHHHHHCCHH
VLTLIEKAQATVDEEKAKELEQKMRTLSFTLDDFLEQLGQVRQLGPLDELLGMLPGANKI
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHH
KGLKNAKVDDKQIGHIEAIIRSMTKLEREQPEIINASRKKRIAKGSGTTVQEINRLLKQF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHHHHHCCCCCCHHHHHHHHHHH
EDMKKMMKTLTGMQKGKKKGLGGLKFPFM
HHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AFEGLADRLQQTMQKIRGKGKVSEADVKEMMREVRLALLEADVNFKVVKDFVKRVSERA
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
VGQDVMKSLTPGQQVIKVVQEELTGLMGGEQSKIAVANKPPTVIMMVGLQGAGKTTTTGK
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEEECCCCCCCCCHHH
LANLLRKKHNRKPMLVAADIYRPAAIKQLETLGKQLDMPVFSLGDQVSPVEIAKQAIAKA
HHHHHHHHHCCCCEEEEHHHHCHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHH
KEEHHDYVLIDTAGRLHIDEELMDELAKVKEVANPDEIFLVVDAMTGQDAVNVAKSFHEQ
HHHCCCEEEEECCCCEEECHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHH
LGLTGVVLTKLDGDTRGGAALSIKAVTNTPIKFAGMGEKLDAIEPFHPERMASRILGMGD
HCCCEEEEEEECCCCCCCCEEEEEEECCCCEEECCCCCCCCCCCCCCHHHHHHHHHCCHH
VLTLIEKAQATVDEEKAKELEQKMRTLSFTLDDFLEQLGQVRQLGPLDELLGMLPGANKI
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHH
KGLKNAKVDDKQIGHIEAIIRSMTKLEREQPEIINASRKKRIAKGSGTTVQEINRLLKQF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHHHHHCCCCCCHHHHHHHHHHH
EDMKKMMKTLTGMQKGKKKGLGGLKFPFM
HHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8335643; 9384377; 7511896 [H]