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The map label for this gene is fruR [H]

Identifier: 152976112

GI number: 152976112

Start: 2483351

End: 2484100

Strand: Reverse

Name: fruR [H]

Synonym: Bcer98_2396

Alternate gene names: 152976112

Gene position: 2484100-2483351 (Counterclockwise)

Preceding gene: 152976113

Following gene: 152976111

Centisome position: 60.78

GC content: 34.93

Gene sequence:

>750_bases
ATGTTAACGCCTGAACGTCATCAGCTTATTTTAAAGCTTGTGAAGGAATATAATGTTGTGAAATTGCAGGAGTTAGTAGA
AAGGACAAAAAGTTCGGAATCAACTATTCGTCGTGATTTAGCACAGCTAGAAAAACAACGCTTATTAAAAAGAGTGCATG
GTGGAGCTTCCGTGTTATCGGGAAAAGGTCAAGAGCCTACAATGGTTGAAAAATCAACCAAAAACATTCAAGAAAAACGA
GCGATTGCTAGTTTGGCAGCTTCTTTAGTTGAAAAGGGTGATTGTATTTATTTAGATGCAGGGAGTACAACGTTTGAAAT
GATTCCATATTTAATAAATAAGGATGTGACAGTTGTCACAAATGGATTGATGCATATAGAGGCTTTAGTTGAAAATCATA
TTCGTGCATATTTGCTTGGTGGAATGATGAAAAGTCAAACAAAAGCTTTAATTGGTGCAATGGCACAAGAAAGTATGCAG
AAATATCGATTTGATAAATGTTTCTTAGGAGCAAATGGTGTGCATGAACAACTTGGATATACAACGCCAGATCCAGAGGA
AGCACTACTAAAAAAAATGGCATTAACATTAGCGAATGAAGGATATTTTTTAGTTGATGAAAGTAAGTTTTCCGAAGTTG
CGTTTGCTAAGATTGCTAATATTGAAGATGCGAAAATGATTACTAACGCACTAGAAGAGATAGAAGAATATAGGAAAAAA
ACGAATGTGATTGAGGTTGATAAATCATGA

Upstream 100 bases:

>100_bases
GATGTATTCCGAGAAGGTTGTTTTTGGATGAGTTTGAATGTTTTTGGTTGATTTGTGTGAGGGTTTTTATTATACTGTAA
TCAAAGAAGAGGTGAATGAT

Downstream 100 bases:

>100_bases
TCTATACAGTGACATTAAATCCATCTATTGATTATGTTGTTCAAGTAGAGCCCTTTATGTTAGGAACTGTGAACAGAGCG
GAAAAAGATATGAAATTCCC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MLTPERHQLILKLVKEYNVVKLQELVERTKSSESTIRRDLAQLEKQRLLKRVHGGASVLSGKGQEPTMVEKSTKNIQEKR
AIASLAASLVEKGDCIYLDAGSTTFEMIPYLINKDVTVVTNGLMHIEALVENHIRAYLLGGMMKSQTKALIGAMAQESMQ
KYRFDKCFLGANGVHEQLGYTTPDPEEALLKKMALTLANEGYFLVDESKFSEVAFAKIANIEDAKMITNALEEIEEYRKK
TNVIEVDKS

Sequences:

>Translated_249_residues
MLTPERHQLILKLVKEYNVVKLQELVERTKSSESTIRRDLAQLEKQRLLKRVHGGASVLSGKGQEPTMVEKSTKNIQEKR
AIASLAASLVEKGDCIYLDAGSTTFEMIPYLINKDVTVVTNGLMHIEALVENHIRAYLLGGMMKSQTKALIGAMAQESMQ
KYRFDKCFLGANGVHEQLGYTTPDPEEALLKKMALTLANEGYFLVDESKFSEVAFAKIANIEDAKMITNALEEIEEYRKK
TNVIEVDKS
>Mature_249_residues
MLTPERHQLILKLVKEYNVVKLQELVERTKSSESTIRRDLAQLEKQRLLKRVHGGASVLSGKGQEPTMVEKSTKNIQEKR
AIASLAASLVEKGDCIYLDAGSTTFEMIPYLINKDVTVVTNGLMHIEALVENHIRAYLLGGMMKSQTKALIGAMAQESMQ
KYRFDKCFLGANGVHEQLGYTTPDPEEALLKKMALTLANEGYFLVDESKFSEVAFAKIANIEDAKMITNALEEIEEYRKK
TNVIEVDKS

Specific function: Probable Repressor For The Aga Operon For N-Acetyl Galactosamine Transport And Metabolism. [C]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=230, Percent_Identity=33.4782608695652, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI226510968, Length=216, Percent_Identity=32.8703703703704, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1789059, Length=230, Percent_Identity=31.304347826087, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787540, Length=250, Percent_Identity=29.6, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789829, Length=219, Percent_Identity=31.5068493150685, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1787063, Length=238, Percent_Identity=29.4117647058824, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788069, Length=223, Percent_Identity=28.2511210762332, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790753, Length=229, Percent_Identity=25.3275109170306, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87082344, Length=223, Percent_Identity=25.5605381165919, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1790635, Length=240, Percent_Identity=29.1666666666667, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789170, Length=227, Percent_Identity=25.5506607929515, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27928; Mature: 27928

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTPERHQLILKLVKEYNVVKLQELVERTKSSESTIRRDLAQLEKQRLLKRVHGGASVLS
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHC
GKGQEPTMVEKSTKNIQEKRAIASLAASLVEKGDCIYLDAGSTTFEMIPYLINKDVTVVT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCHHHHH
NGLMHIEALVENHIRAYLLGGMMKSQTKALIGAMAQESMQKYRFDKCFLGANGVHEQLGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCC
TTPDPEEALLKKMALTLANEGYFLVDESKFSEVAFAKIANIEDAKMITNALEEIEEYRKK
CCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
TNVIEVDKS
CCCEEECCC
>Mature Secondary Structure
MLTPERHQLILKLVKEYNVVKLQELVERTKSSESTIRRDLAQLEKQRLLKRVHGGASVLS
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHC
GKGQEPTMVEKSTKNIQEKRAIASLAASLVEKGDCIYLDAGSTTFEMIPYLINKDVTVVT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCHHHHH
NGLMHIEALVENHIRAYLLGGMMKSQTKALIGAMAQESMQKYRFDKCFLGANGVHEQLGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCC
TTPDPEEALLKKMALTLANEGYFLVDESKFSEVAFAKIANIEDAKMITNALEEIEEYRKK
CCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
TNVIEVDKS
CCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]