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The map label for this gene is kipR [H]

Identifier: 152976048

GI number: 152976048

Start: 2418101

End: 2418853

Strand: Reverse

Name: kipR [H]

Synonym: Bcer98_2324

Alternate gene names: 152976048

Gene position: 2418853-2418101 (Counterclockwise)

Preceding gene: 152976051

Following gene: 152976047

Centisome position: 59.18

GC content: 35.86

Gene sequence:

>753_bases
ATGCCTGTGCAATCTATTGATCGAGCAATCAGTATTATAAAACTATTGTATTCAGAAAATGATAAGGAACATTGGGCTAT
TTCTGATATAGCTGATAGAACACATCTGCCAGTTAGTACAGTGCATAGAATATTAAATTCTTTAATGGAACATGGATTAG
TTACACAGATTCCGGAAACGAAGCATTATACAATCGGACCGATGTGGATGGAAGTAGGTCTACGGCAATTAGAAAAAGTA
GACTATCGATCTGTCGCAAGAGAAGTAATGAAACGCTTAGCATATGAAGTGGAAGAAAGCGTATACTTAAATATTCCAAA
TGGGACACATTCTATTATTATTGAGAGAATAGATAGTCCTTTAAAGATTCGTGTTATCGATAATTTAGGAGAACAAATTC
CACTTTCCATCGGTGCTGCTAATAAAACGATACTTGCGAATATGAAAACAAATGAGGTAGAACATATTGTAGATCAGCTA
TTGCCTTCTATATCAGAGCAAAAACAACGGCTATTTGATCAGCTTACTGTGATAAGAAGAGAAGGATATGCGGTAAGTTA
TGGTGAGAAGACAGAAGGAACCGCATCAATTGCTGCACCCATTATAGGTTTTAATCATAAAGTGGTAGGAGCAATCAGTA
TTGGATTAATTAGTGAACGGATTAATGAGGAGCGATTGGCTTTTCTTGTTAATCAGGTTATAAATGCTGCGAATGAAATA
TCAATAAAAATCGGCGGAACAGGAAAGGAATAG

Upstream 100 bases:

>100_bases
TTTTTTGAAAATTAAATAATTTGTTTGATTTCTTGAGAAGATTTTGTTAAATTGGTAGATAATTAAGGTTAGTTAGATAT
TATGAGTGAAGTTGAGGAGC

Downstream 100 bases:

>100_bases
GAGAATATTCTGTCGTTTTTTATTCATATATTGGAATTGATTTTCATAATACGGAAAACAGGGGGATATATATGGCAAAA
TGGCAGACAAAAGAAGAGTT

Product: regulatory protein IclR

Products: NA

Alternate protein names: Kip operon repressor protein [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MPVQSIDRAISIIKLLYSENDKEHWAISDIADRTHLPVSTVHRILNSLMEHGLVTQIPETKHYTIGPMWMEVGLRQLEKV
DYRSVAREVMKRLAYEVEESVYLNIPNGTHSIIIERIDSPLKIRVIDNLGEQIPLSIGAANKTILANMKTNEVEHIVDQL
LPSISEQKQRLFDQLTVIRREGYAVSYGEKTEGTASIAAPIIGFNHKVVGAISIGLISERINEERLAFLVNQVINAANEI
SIKIGGTGKE

Sequences:

>Translated_250_residues
MPVQSIDRAISIIKLLYSENDKEHWAISDIADRTHLPVSTVHRILNSLMEHGLVTQIPETKHYTIGPMWMEVGLRQLEKV
DYRSVAREVMKRLAYEVEESVYLNIPNGTHSIIIERIDSPLKIRVIDNLGEQIPLSIGAANKTILANMKTNEVEHIVDQL
LPSISEQKQRLFDQLTVIRREGYAVSYGEKTEGTASIAAPIIGFNHKVVGAISIGLISERINEERLAFLVNQVINAANEI
SIKIGGTGKE
>Mature_249_residues
PVQSIDRAISIIKLLYSENDKEHWAISDIADRTHLPVSTVHRILNSLMEHGLVTQIPETKHYTIGPMWMEVGLRQLEKVD
YRSVAREVMKRLAYEVEESVYLNIPNGTHSIIIERIDSPLKIRVIDNLGEQIPLSIGAANKTILANMKTNEVEHIVDQLL
PSISEQKQRLFDQLTVIRREGYAVSYGEKTEGTASIAAPIIGFNHKVVGAISIGLISERINEERLAFLVNQVINAANEIS
IKIGGTGKE

Specific function: Transcriptional repressor of the kip gene-containing operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=251, Percent_Identity=26.2948207171315, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788131, Length=246, Percent_Identity=26.8292682926829, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786715, Length=247, Percent_Identity=29.5546558704453, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI87082359, Length=251, Percent_Identity=25.0996015936255, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788581, Length=248, Percent_Identity=25, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1789999, Length=252, Percent_Identity=24.6031746031746, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27996; Mature: 27864

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVQSIDRAISIIKLLYSENDKEHWAISDIADRTHLPVSTVHRILNSLMEHGLVTQIPET
CCHHHHHHHHHHHHHHHCCCCCCCEEHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCCCC
KHYTIGPMWMEVGLRQLEKVDYRSVAREVMKRLAYEVEESVYLNIPNGTHSIIIERIDSP
CCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHCCCC
LKIRVIDNLGEQIPLSIGAANKTILANMKTNEVEHIVDQLLPSISEQKQRLFDQLTVIRR
EEEEEEHHCCCCCCEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGYAVSYGEKTEGTASIAAPIIGFNHKVVGAISIGLISERINEERLAFLVNQVINAANEI
CCCEEECCCCCCCCHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
SIKIGGTGKE
EEEECCCCCC
>Mature Secondary Structure 
PVQSIDRAISIIKLLYSENDKEHWAISDIADRTHLPVSTVHRILNSLMEHGLVTQIPET
CHHHHHHHHHHHHHHHCCCCCCCEEHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCCCC
KHYTIGPMWMEVGLRQLEKVDYRSVAREVMKRLAYEVEESVYLNIPNGTHSIIIERIDSP
CCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHCCCC
LKIRVIDNLGEQIPLSIGAANKTILANMKTNEVEHIVDQLLPSISEQKQRLFDQLTVIRR
EEEEEEHHCCCCCCEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGYAVSYGEKTEGTASIAAPIIGFNHKVVGAISIGLISERINEERLAFLVNQVINAANEI
CCCEEECCCCCCCCHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
SIKIGGTGKE
EEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]