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The map label for this gene is polC [H]

Identifier: 152975987

GI number: 152975987

Start: 2360126

End: 2361025

Strand: Reverse

Name: polC [H]

Synonym: Bcer98_2260

Alternate gene names: 152975987

Gene position: 2361025-2360126 (Counterclockwise)

Preceding gene: 152975988

Following gene: 152975986

Centisome position: 57.77

GC content: 34.78

Gene sequence:

>900_bases
GTGGGATATGTATCTTTACCAGCAAATTATGTTGTAATTGATTTTGAGACGACAGGTTTTCACCCATATAACGATCGGAT
CATTCAAGTAGCCGCAGTTCGATATCGCAATCATGAATTAGCAGACCAATTTGTTTCATTCGTAAATCCAGAAAGATCGA
TACCGAGTCGAATCACAAGCTTAACAGGAATTACGAACTATCGTGTTTCAGATGCACCAACTGTTCAAGAAGTGTTACCG
TTATTTTTAGCGTTTTTAGGTAACGATACAATTGTTGCCCACAACGCCTCTTTTGATATGCGTTTTTTAAAAAGTAATAT
GAGCAGATTTCAATTAGGAGAGCCGAACAATAAGGTGATTGACACAGTACTTTTAGCTAAAAAATATATGAAACACGCTC
CAAACTTTAAGCTGGAAACATTAAAAAGAATGCTGGGTATACGATTAAGTTCCCATAATGCACTGGATGATTGTATAACA
TGTGCAGCCGTTTATCAACAGTGTGCAAATATGCAAGGGGACGGGCGAAAGAGTCTGAAAAAAGAAGTAATGGAAGAAGA
GACTGTATATACGCTCATAAAAGAAATGCTAATAAAGAATAATCGTACAGTAGAGTATATTCGTTATGTAAGTACCGGTA
ATTATTTAGATATAAAAGCTTTTCAGTTAATTGCGAGAATGAAAGTGAAAGGGCGAAAAAAATATGTATTAACAGAAAAA
ACAGAACGAGAAATACAAGCAATCTGCGCGGATTTAAAATGTGAACCAGCTTTAAAAAATGAATTAGGTATAACGAGAAT
TATGGTTGAAAGTTTAGAGGATGTCATGAAATTAGAAAGTTATATTTTAGCTCGGTATGATTTCCTACTACAAGCTGCAC
AGGAGTACAATGAAATATAA

Upstream 100 bases:

>100_bases
CAGAATTGATATCAGATCGGTTCTGTCTTTTCTTTTTCAAGAAAAGATTTGTTCATGATATGATATAGGAAATAAAAATA
ATCAGTAAGGGGAGTATGTT

Downstream 100 bases:

>100_bases
GTAGATACAAAAAATCCATTCCGAGAATGGCTTTTTTGTATTATAAACTTTTCTGCGCTAAAACAAAAAATTTTCTTGCA
AATCTGATTAAAGAGATTTC

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: PolIII [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MGYVSLPANYVVIDFETTGFHPYNDRIIQVAAVRYRNHELADQFVSFVNPERSIPSRITSLTGITNYRVSDAPTVQEVLP
LFLAFLGNDTIVAHNASFDMRFLKSNMSRFQLGEPNNKVIDTVLLAKKYMKHAPNFKLETLKRMLGIRLSSHNALDDCIT
CAAVYQQCANMQGDGRKSLKKEVMEEETVYTLIKEMLIKNNRTVEYIRYVSTGNYLDIKAFQLIARMKVKGRKKYVLTEK
TEREIQAICADLKCEPALKNELGITRIMVESLEDVMKLESYILARYDFLLQAAQEYNEI

Sequences:

>Translated_299_residues
MGYVSLPANYVVIDFETTGFHPYNDRIIQVAAVRYRNHELADQFVSFVNPERSIPSRITSLTGITNYRVSDAPTVQEVLP
LFLAFLGNDTIVAHNASFDMRFLKSNMSRFQLGEPNNKVIDTVLLAKKYMKHAPNFKLETLKRMLGIRLSSHNALDDCIT
CAAVYQQCANMQGDGRKSLKKEVMEEETVYTLIKEMLIKNNRTVEYIRYVSTGNYLDIKAFQLIARMKVKGRKKYVLTEK
TEREIQAICADLKCEPALKNELGITRIMVESLEDVMKLESYILARYDFLLQAAQEYNEI
>Mature_298_residues
GYVSLPANYVVIDFETTGFHPYNDRIIQVAAVRYRNHELADQFVSFVNPERSIPSRITSLTGITNYRVSDAPTVQEVLPL
FLAFLGNDTIVAHNASFDMRFLKSNMSRFQLGEPNNKVIDTVLLAKKYMKHAPNFKLETLKRMLGIRLSSHNALDDCITC
AAVYQQCANMQGDGRKSLKKEVMEEETVYTLIKEMLIKNNRTVEYIRYVSTGNYLDIKAFQLIARMKVKGRKKYVLTEKT
EREIQAICADLKCEPALKNELGITRIMVESLEDVMKLESYILARYDFLLQAAQEYNEI

Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG2176

COG function: function code L; DNA polymerase III, alpha subunit (gram-positive type)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

Organism=Escherichia coli, GI1786409, Length=200, Percent_Identity=26, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011708
- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR006308
- InterPro:   IPR012337 [H]

Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP; PF01336 tRNA_anti [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 34337; Mature: 34206

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYVSLPANYVVIDFETTGFHPYNDRIIQVAAVRYRNHELADQFVSFVNPERSIPSRITS
CCEEECCCCEEEEEEECCCCCCCCCHHEEHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHH
LTGITNYRVSDAPTVQEVLPLFLAFLGNDTIVAHNASFDMRFLKSNMSRFQLGEPNNKVI
HHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCHHHEECCCCCHHHH
DTVLLAKKYMKHAPNFKLETLKRMLGIRLSSHNALDDCITCAAVYQQCANMQGDGRKSLK
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHH
KEVMEEETVYTLIKEMLIKNNRTVEYIRYVSTGNYLDIKAFQLIARMKVKGRKKYVLTEK
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEHHHHHHHHHHHHCCCCEEEECCH
TEREIQAICADLKCEPALKNELGITRIMVESLEDVMKLESYILARYDFLLQAAQEYNEI
HHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GYVSLPANYVVIDFETTGFHPYNDRIIQVAAVRYRNHELADQFVSFVNPERSIPSRITS
CEEECCCCEEEEEEECCCCCCCCCHHEEHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHH
LTGITNYRVSDAPTVQEVLPLFLAFLGNDTIVAHNASFDMRFLKSNMSRFQLGEPNNKVI
HHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCHHHEECCCCCHHHH
DTVLLAKKYMKHAPNFKLETLKRMLGIRLSSHNALDDCITCAAVYQQCANMQGDGRKSLK
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHH
KEVMEEETVYTLIKEMLIKNNRTVEYIRYVSTGNYLDIKAFQLIARMKVKGRKKYVLTEK
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEHHHHHHHHHHHHCCCCEEEECCH
TEREIQAICADLKCEPALKNELGITRIMVESLEDVMKLESYILARYDFLLQAAQEYNEI
HHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]